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Results for "

PKMYT1 inhibitor

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-147312
    GSK-1520489A

    		Others Cancer
    GSK-1520489A is a PKMYT1 (active protein kinase) inhibitor (IC50=115 nM, Ki=10.94 nM) .
    GSK-1520489A
  • HY-145817A
    lunresertib
    1 Publications Verification

    RP-6306

    		 Wee1 Cancer
    lunresertib (RP-6306) is a potent, selective and orally active PKMYT1 inhibitor with an IC50 of 14 nM. lunresertib shows a high degree of selectivity over other kinases in cellular binding assays. lunresertib shows anticancer effects .
    lunresertib
  • HY-163491
    PKMYT1-IN-2

    		Wee1 Cancer
    PKMYT1-IN-2 (compound 2) is a potent PKMYT1 inhibitor with an IC50 of 5.7 nM. PKMYT1-IN-2 inhibits the growth of HCC1569 cells with an IC50 of 22 nM .
    PKMYT1-IN-2
  • HY-162849
    PKMYT1-IN-3

    		Wee1 Cancer
    PKMYT1-IN-3 (compound 8ma) is a potent and selective PKMYT1 inhibitor with an IC50 value of 16.5 nM. PKMYT1-IN-3 has antitumor activity .
    PKMYT1-IN-3
  • HY-162987
    PKMYT1-IN-6

    		Wee1 Cancer
    PKMYT1-IN-6 (compund 98) is a PKMYT1 inhibitor with IC50 less than 50 nM .
    PKMYT1-IN-6
  • HY-162986
    PKMYT1-IN-4

    		Wee1 Cancer
    PKMYT1-IN-4 (compund 27) is a PKMYT1 inhibitor with IC50 less than 50 nM .
    PKMYT1-IN-4
  • HY-163490
    PKMYT1-IN-1

    		Others Cancer
    PKMYT1-IN-1 (Compound 1) is an inhibitor for membrane-associated tyrosine and threonine kinase (PKMYT1), with an IC50 of 8.8 nM. PKMYT1-IN-1 inhibits proliferation of tumor cell HCC1569 with IC50 of 42 nM .
    PKMYT1-IN-1
  • HY-169946
    WEE1/PKMYT1-IN-1

    		Wee1 Cancer
    WEE1/PKMYT1-IN-1 (compound 75) is a potent and orally active WEE1 and PKMYT1 inhibitor. WEE1/PKMYT1-IN-1 shows antiproliferation activity .
    WEE1/PKMYT1-IN-1
  • HY-170517
    PKMYT1-IN-8

    		Wee1 Ephrin Receptor Cancer
    PKMYT1-IN-8 (Compound 137) is the inhibitor for PKMYT1 with an IC50 of 9 nM. PKMYT1-IN-8 inhibits EPHB3, EPHA1, KIT, EPHB1, EPHA2, EPHA3, and EPHB2with IC50s of 1.79, 3.17, 4.29, 6.32, 6.83, 8.10, and 10.9 μM, respectively. PKMYT1-IN-8 inhibits the proliferation of cancer cell OVCAR3 with GI50 of 2.02 μM .
    PKMYT1-IN-8

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