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Pathways Recommended: PROTAC
Results for "

PROTAC SMARCA2/4-degrader-8

" in MedChemExpress (MCE) Product Catalog:

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-159460
    PROTAC SMARCA2/4-degrader-8

    		PROTACs Epigenetic Reader Domain Cancer
    PROTAC SMARCA2/4-degrader-8 (Compound I-502) is a PROTAC degrader for catalytic subunit of the SWI/SNF complex SMARCA2. PROTAC SMARCA2/4-degrader-8 degrades SMARCA2 with DC50 <100 nM in A549 and in MV411, degrades SMARCA4 with DC50<100 nM in MV411(Pink: Ligand for target protein (HY-159545); Black: Linker (HY-W063924); Blue: Ligand for E3 ligase (S,R,S)-AHPC (HY-125845))
    PROTAC SMARCA2/4-degrader-8
  • HY-W063924
    Bpin-Cyclohexene-C-COOEt

    Ethyl-2-(4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3- enyl)acetate

    		 PROTAC Linkers Cancer
    Bpin-Cyclohexene-C-COOEt is a PROTAC linker. Bpin-Cyclohexene-C-COOEt can be used in synthesis PROTAC SMARCA2/4-degrader-8 (HY-159460) .
    Bpin-Cyclohexene-C-COOEt

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