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Probe,pH insensitive

" in MedChemExpress (MCE) Product Catalog:

31

Inhibitors & Agonists

21

Fluorescent Dye

2

Peptides

8

Recombinant Proteins

3

Antibodies

2

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-33350

    Potassium Channel Apoptosis Cardiovascular Disease Cancer
    Clofilium tosylate, a potassium channel blocker, induces apoptosis of human promyelocytic leukemia (HL-60) cells via Bcl-2-insensitive activation of caspase-3. Antiarrhythmic agent .
    Clofilium tosylate
  • HY-101620
    MRZ 2-514
    1 Publications Verification

    iGluR Neurological Disease
    MRZ 2-514 is an antagonist of the strychnine-insensitive modulatory site of the NMDA receptor (glycineB), with Ki of 33 μM.
    MRZ 2-514
  • HY-15942
    5-TAMRA
    2 Publications Verification

    Fluorescent Dye Others
    5-TAMRA can produce bright, pH-insensitive orange-red fluorescence (excitation and emission extremes of 546/579) and has good photostability.
    5-TAMRA
  • HY-D0048
    5-TAMRA-SE
    2 Publications Verification

    5-TAMRA-NHS ester; 5-Carboxytetramethylrhodamine succinimidyl ester

    Fluorescent Dye Others
    5-TAMRA-SE is an amine-reactive fluorescent agent, and its conjugate produces bright, pH-insensitive orange-red fluorescence with good photostability.
    5-TAMRA-SE
  • HY-D1591

    Fluorescent Dye Others
    BODIPY R6G methyl ester (compound 5′-1) is a BODIPY-like fluorescent dye with good light stability and insensitive to pH value. BODIPY R6G methyl ester shows good photostability, high sensitivity and insensitive to pH value. BODIPY R6G methyl ester can be used in research areas such as photodynamic research, PH probes, ion recognition, photocatalysis, protein labeling, cell imaging, and proteomic analysis .
    BODIPY R6G methyl ester
  • HY-100798

    GABA Receptor Neurological Disease
    Phaclofen is a selective GABAB receptor antagonist. Phaclofen is a peripheral and central baclofen antagonist. Phaclofen maybe a potential compound in determining the physiological significance of central and peripheral bicuculline-insensitive receptors with which GABA and (-)-baclofen interact .
    Phaclofen
  • HY-149680

    Others Others
    CatD-P1is a pH insensitive CatD (Cathepsin D) probe .
    CatD-P1
  • HY-159687

    WCK 4873

    Antibiotic Bacterial Infection
    Nafithromycin (WCK 4873) is an orally available antibiotic that inhibits community-acquired pneumonia caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Methicillin (HY-121544)-susceptible Staphylococcus aureus. The MIC90 of nafithromycin against macrolide-resistant and telithromycin (HY-A0062)-insensitive Streptococcus pneumoniae is 0.12 mg/liter .
    Nafithromycin
  • HY-148649

    Antibiotic Others
    Demethyl bleomycin A2 is a Bleomycin (HY-108345) congener. The DNA cleavage of demethyl bleomycin A2 is insensitive to the presence of 5-Methylcytidine (HY-113135) .
    Demethyl bleomycin A2
  • HY-D1111

    AFDye 568 NHS Ester

    Fluorescent Dye Others
    TFAX 568, SE is an orange fluorescent dye and exhibits pH-insensitivity over a very broad range (pH in the 4-10). TFAX 568, SE yields exceptionally bright, photostable conjugates with proteins or antibodies (such as goat anti-mouse IgG) .
    TFAX 568, SE
  • HY-D1610

    Fluorescent Dye Others
    BODIPY FL C5 is a green fluorescent fatty acid. BODIPY FL C5 can be used as a precursor for the synthesis of various fluorescent phospholipids. BODIPY FL C5 is relatively insensitive to the environment and fluoresces in both water-soluble and lipid environments .
    BODIPY FL C5
  • HY-D1110

    Fluorescent Dye Others
    TFAX 594,SE is a red fluorescent dye and exhibits pH-insensitivity over a very broad range (pH in the 4-10). TFAX 594,SE yields exceptionally bright, photostable conjugates with proteins or antibodies (such as goat anti-mouse IgG) .
    TFAX 594,SE
  • HY-108905

    Human IGF-I; FK 780

    IGF-1R Metabolic Disease
    Mecasermin (Human IGF-I; FK 780) is a recombinant human insulin-like growth factor I (IGF-I). Mecasermin has the potential for the study of the growth failure of growth hormone (GH) insensitivity caused by GH receptor defects or GH-inhibiting antibodies .
    Mecasermin
  • HY-D1113

    Fluorescent Dye Others
    TFAX 488,TFP is a green fluorescent dye and exhibits pH-insensitivity over a very broad range (pH in the 4-10). TFAX 488,TFP yields exceptionally bright, photostable conjugates with proteins or antibodies (such as goat anti-mouse IgG, streptavidin) .
    TFAX 488,TFP
  • HY-110257

    Fluorescent Dye Others
    BODIPY FL-X,SE is a fluorescent greendye for the labeling of amine, shows a high fluorescence quantum yield and is relatively insensitive to pH change. BODIPY FL-X,SE can be used as an alternative for FAM, Cy2 or FITC. λabs: 504 nm; λem:510 nm .
    BDY FL-X, SE
  • HY-114352

    Fluorescent Dye Others
    BODIPY FL-X is a green-fluorescent dye. BODIPY FL-X has the succinimidyl ester covalently coupled to proteins. BODIPY FL-X has high fluorescence quantum yield and is relatively insensitive to pH change. (λex=504 nm, λem=510 nm) .
    BODIPY FL-X
  • HY-D1114

    Fluorescent Dye Others
    TFAX 488,SE dilithium is a green fluorescent dye and exhibits pH-insensitivity over a very broad range (pH in the 4-10). TFAX 488,SE dilithium yields exceptionally bright, photostable conjugates with proteins or antibodies (such as goat anti-mouse IgG, streptavidin) .
    TFAX 488,SE dilithium
  • HY-D2083

    Fluorescent Dye Cancer
    BODIPY 540 (purity>98%) is a BODIPY dye.BODIPY dye is a small molecule dye with strong UV absorption ability.Its fluorescence peak is relatively sharp, its quantum yield is high, and it is relatively insensitive to the polarity and pH value of the environment.BODIPY 540 (purity>98%) has a purity higher than 98% and is suitable for cell experiments .
    BODIPY 540 (purity 99%)
  • HY-P10180

    APP (319-335)

    Amyloid-β Neurological Disease
    β-Amyloid/A4 Protein Precusor (319-335) (APP (319-335)) is a peptide fragment of β-Amyloid/A4 protein precursor (APP). β-Amyloid/A4 Protein Precusor (319-335) can recognize the heparinase-insensitive site that contains the neuritotropic activity of APP .
    β-Amyloid/A4 Protein Precusor (319-335)
  • HY-163110

    HIV Reverse Transcriptase Infection
    NNRT-IN-2 (compound 7w) is an orally available non-nucleoside reverse transcriptase inhibitor (NNRTI) with broad inhibitory effects on wild-type HIV-1 and mutant strains. NNRT-IN-2 inhibits HIV-1 reverse transcriptase with an EC50 of 22 nM. NNRT-IN-2 is insensitive to CYP and hERG and has good safety and pharmacokinetic characteristics .
    NNRT-IN-2
  • HY-D1755

    Fluorescent Dye Others
    Fluo-3FF AM is a low affinity (Kd = 42 μM) fluorescent Ca 2+ sensitive indicator (Abs/Em = 462 nm/526 nm). Fluo-3FF AM is Mg 2+ insensitive and relatively photostable. Fluo-3FF AM is an analog of Fluo-3FF AM. Fluo-3FF AM is essentially non-fluorescent, but exhibits a strong fluorescence enhancement upon entry into cells and binding to calcium.
    Fluo-3FF AM
  • HY-D1069

    DBCO-Sulfo-Cy3

    Fluorescent Dye Others
    DBCO-Cy3 (DBCO-Sulfo-Cy3) is the derivative of Cyanine3 fluorophore, a pH insensitive from pH (4-10) orange fluorescent dyewith excitation maximum 555 nm and emission maximum of 580nm. DBCO-Cy3 has fast reaction kinetics and good stability, and is productive to use in many standard fluorescent instrumentations. DBCO-Cy3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-Cy3
  • HY-D1106

    Fluorescent Dye Cancer
    BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions . Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells .
    Py-BODIPY-NHS ester
  • HY-D1482

    Fluorescent Dye Others
    Cy5 Tetrazine is a water-soluble, pH-insensitive from pH 4 to pH 10, far-red-fluorescent probe with excitation ideally suited for the 633 nm or 647 nm laser lines. Its absorption and emission spactra are almost identical to those of Alexa Fluor 647, CF 647 Dye, or any other Cyanine5 based fluorescent dyes. Sulfo-Cy5-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Sulfo-Cy5-tetrazine
  • HY-D1447

    Fluorescent Dye Others
    Fluo-3FF pentapotassium is a cell-permeable acetoxy-methyl ester of Fluo-3FF, a fluorescent calcium indicator. Fluo-3FF is a di-fluorinated analog of Fluo-3 with a 100-fold lower affinity than Fluo-3 for calcium (Kds = 42 and 0.4 碌M, respectively). For its low affinity, Fluo-3FF is used for studying compartments with high concentrations of calcium, such as endoplasmic reticulum, where high affinity dyes will be insensitive to luminal fluctuations.
    Fluo-3FF pentapotassium
  • HY-D1237
    BODIPY 505/515
    1 Publications Verification

    Fluorescent Dye Metabolic Disease
    BODIPY505/515 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 505/515 nm .
    BODIPY 505/515
  • HY-D1570

    Fluorescent Dye Others
    BODIPYFL C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 480/508 nm .
    BODIPY FL C12
  • HY-W090090
    BODIPY 493/503
    Maximum Cited Publications
    21 Publications Verification

    Pyrromethene 546; BDP 493/503 lipid stain

    Fluorescent Dye Others
    BODIPY493/503 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 493/503 nm .
    BODIPY 493/503
  • HY-138226

    Fluorescent Dye Others
    BODIPY 558/568 C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 558/568 nm .
    BODIPY 558/568 C12
  • HY-D1614
    BODIPY 493/503 methyl bromide
    5 Publications Verification

    Fluorescent Dye Others
    BODIPY493/503 methyl bromide is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 493/503 nm .
    BODIPY 493/503 methyl bromide
  • HY-D1617

    Fluorescent Dye Others
    BODIPY 500/510 C1, C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 500/510 nm . Protect from light, stored at -20℃.
    BODIPY 500/510 C1, C12

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