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Results for "

Ser396

" in MedChemExpress (MCE) Product Catalog:

By Targets:	GSK-3 (1) OGA (1)
By Research Areas:	Neurological Disease (2)

2

Inhibitors & Agonists

1

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

GSK-3β inhibitor 2 1 Publications Verification	GSK-3	Neurological Disease
GSK-3β inhibitor 2 (Compound 3) is a potent, selective and orally active GSK-3β inhibitor with an IC₅₀ of 1.1 nM. GSK-3β inhibitor 2 can cross the blood-brain barrier. GSK-3β inhibitor 2 has the potential for Alzheimer's disease .

O-GlcNAcase-IN-2	OGA	Neurological Disease
O-GlcNAcase-IN-2 (compound 81) is an orally effective, blood-brain barrier-permeable OGA inhibitor (IC₅₀=4.93 nM). O-GlcNAcase-IN-2 can increase the O-GlcNAcylation level of proteins and phosphorylation of tau (p-Ser199, p-Thr205 and p-Ser396) in the OA-damaged SH-SY5Y cell model. O-GlcNAcase-IN-2 can also improve cognitive impairment in APP/PS1 mice and has potential anti-Alzheimer's disease (AD) effects .

Cat. No.	Compare	Product Name	Application	Reactivity

	*Phospho-Tau (Ser396) Antibody*	WB, ICC/IF, IHC-P	Mouse, Rat, Human
	Phospho-Tau (Ser396) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 79 kDa, targeting to Phospho-Tau(S396). It can be used for WB,ICC/IF,IHC-P assays with tag free, in the background of Mouse, Rat, Human.

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