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Results for "

Thalidomide-4-NH-PEG2-COO(t-Bu)

" in MedChemExpress (MCE) Product Catalog:

2

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1

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W584524

    Ligands for E3 Ligase Cancer
    Thalidomide-4-NH-PEG2-COO(t-Bu) is a t-Bu modified Thalidomide (HY-14658), which acts as a Cereblon ligand to recruit CRBN protein. The t-Bu protecting group at the end of Thalidomide-4-NH-PEG2-COO(t-Bu) can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-4-NH-PEG2-COO(t-Bu) is a key intermediate in the synthesis of CRBN-based PROTAC molecules.
    Thalidomide-4-NH-PEG2-COO(t-Bu)
  • HY-169232

    PROTACs Cancer
    PCC16 chloride is a CRBN-based cp-PCC with an IC50 value of 102 nM for the degradation of DHHC3. PCC16 chloride has antitumor activity. (Target protein ligand: HY-169235, linker: HY-169236, E3 ligase ligand: HY-10984) .
    PCC16 chloride

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