Results for "

Type 1 kinase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	AMPK (1) Apoptosis (1) DNA/RNA Synthesis (1) Hippo (MST) (2) HSV (2)
By Research Areas:	Infection (2) Metabolic Disease (2)

Inhibitors & Agonists

Screening Libraries

Recombinant Proteins

Antibodies

Targets Recommended: C-type Lectin-like Receptors (CTLRs) Scavenger Receptor Class B type I (SR-BI） PCSK9

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-151257

IHMT-MST1-58	Hippo (MST)	Metabolic Disease
IHMT-MST1-58 is a potent, selective mammalian and orally active *STE20-like protein 1 kinase* (MST1) inhibitor with IC₅₀** value of 23 nM. IHMT-MST1-58 can be used for the research of Type 1/2 diabetes .

HY-W747737A

BVDU 5′-Triphosphate ammonium (E)-5-(2-Bromovinyl)-dUTP ammonium; BVdUTP ammonium	HSV	Infection
BVDU 5′-Triphosphate ammonium is an antivirus agent with 5′-Triphosphate label, targeting viral DNA polymerase. BVDU 5′-Triphosphate ammonium shows excellent selectivity against varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1), due to a specific phosphorylation by the virus-encoded thymidine kinase.

HY-W747737

BVDU 5′-Triphosphate (E)-5-(2-Bromovinyl)-dUTP; BVdUTP	DNA/RNA Synthesis HSV	Infection
BVDU 5′-Triphosphate is an antivirus agent with 5′-Triphosphate label, targeting viral DNA polymerase. BVDU 5′-Triphosphate shows excellent selectivity against varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1), due to a specific phosphorylation by the virus-encoded thymidine kinase.

HY-164595

IHMT-MST1-39	Hippo (MST) Apoptosis AMPK	Metabolic Disease
IHMT-MST1-39 is an orally active inhibitor for MST kinase, with IC₅₀ of 42 nM and 109 nM, for MST1 and MST2. IHMT-MST1-39 activates the AMPK signaling pathway in liver cells, reduces apoptosis of pancreatic β-cells. IHMT-MST1-39 ameliorates diabetes in Streptozotocin (HY-13753)-induced type 1 diabetes (T1D) mouse models .

Cat. No.	Product Name

HY-L165

Dopamine Receptor Compound Library	216 compounds
Dopamine receptor (DAR), widely distributed in the brain, plays a key role in regulating motor function, motivation, driving force and cognition. The role of DA is mediated by D1-type (D1, D5) and D2-type receptors (D2S, D2L, D3, D4), which are distributed in presynaptic, postsynaptic and extrasynaptic, projection neurons and interneurons. Each receptor has a different function. D1 and D5 receptors couple with G stimulation sites and activate Adenylyl cyclase. The activation of Adenylyl cyclase leads to the production of the second messenger cAMP, which leads to the production of protein kinase A (PKA), which leads to further transcription in the nucleus. D2 to D4 receptors are coupled to G inhibitory sites to inhibit adenylyl cyclase and activate potassium Ion channel. These receptors utilize phosphorylation cascades or direct membrane interactions to affect the functions of voltage-gated and neurotransmitter-gated channels, cytoplasmic enzymes, and transcription factors. Dopamine receptor plays an important role in daily life. MCE designs a unique collection of 216 small molecules related to dopamine receptor. It is a good tool for screening drugs from nervous system disease.

Dopamine Receptor Compound Library

216 compounds

Dopamine receptor (DAR), widely distributed in the brain, plays a key role in regulating motor function, motivation, driving force and cognition. The role of DA is mediated by D1-type (D1, D5) and D2-type receptors (D2S, D2L, D3, D4), which are distributed in presynaptic, postsynaptic and extrasynaptic, projection neurons and interneurons. Each receptor has a different function. D1 and D5 receptors couple with G stimulation sites and activate Adenylyl cyclase. The activation of Adenylyl cyclase leads to the production of the second messenger cAMP, which leads to the production of protein kinase A (PKA), which leads to further transcription in the nucleus. D2 to D4 receptors are coupled to G inhibitory sites to inhibit adenylyl cyclase and activate potassium Ion channel. These receptors utilize phosphorylation cascades or direct membrane interactions to affect the functions of voltage-gated and neurotransmitter-gated channels, cytoplasmic enzymes, and transcription factors. Dopamine receptor plays an important role in daily life.

MCE designs a unique collection of 216 small molecules related to dopamine receptor. It is a good tool for screening drugs from nervous system disease.

Species:	Human (8)
Tag:	His (4) Avi (1) GST (6) Flag (1)
Source:	HEK293 (1) Sf9 insect cells (6) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P7714

	CAMKI alpha/CAMK1 Protein, Human (HEK293, His) rHuCAMK1, His; Calcium/Calmodulin-Dependent Protein kinase Type 1; CaM kinase I; CaMKI-Alpha; CAMK1	Human	HEK293
	CAMKI alpha/CAMK1 Protein, Human (HEK293, His), a recombinant human CAMK1 produced in HEK293 cells, has a His tag at the N-terminus. CAMK1 is involved in multiple cell functions, including calmodulin binding, ATP binding, signal transduction, development and cell differentiation.

HY-P7715

	CAMKI delta/CAMK1D Protein, Human (GST) rHuCAMK1D, N-GST; Calcium/calmodulin-dependent protein kinase Type 1D; CaMKI-like protein kinase; CAMK1D;	Human	E. coli
	CAMKI delta/CAMK1D Protein, Human (GST), a recombinant human CAMK1D expressed in E. coli, has a GST tag at the N-terminus. CAMK1D acts as a key modulator of tumor-intrinsic immune resistance.

HY-P702654

	CAMK1 alpha Protein, Human (sf9, His, GST) CAMK1; calcium/calmodulin-dependent protein kinase I; calcium/calmodulin-dependent protein kinase Type 1; CaMKI; caM-KI; caMKI-alpha; caM kinase I alpha; CAMKI; MGC120317; MGC120318	Human	Sf9 insect cells
	CAMK1 alpha Protein, Human (sf9, His, GST) is the recombinant human-derived CAMK1 alpha, expressed by Sf9 insect cells , with His, GST labeled tag. The total length of CAMK1 alpha Protein, Human (sf9, His, GST) is 370 a.a.,

HY-P702762

	NTRK1/TrkA-I Protein, Human (Biotinylated, sf9, Flag, Avi) High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor Type 1; NTRK-1; NTRK1; Slow nerve growth factor receptor; p140-TrkA; Trk-A; Trk; Trka; TRK1-transforming tyrosine kinase protein; TRKAOncogene TRK; TRKTRK1; tyrosine kinase receptor A	Human	Sf9 insect cells
	TrkA protein is an important receptor tyrosine kinase that regulates the development of the central and peripheral nervous systems and affects the proliferation, differentiation, and survival of neurons. As a high-affinity receptor for NGF, TrkA is activated upon NGF binding through homodimerization and autophosphorylation. NTRK1/TrkA-I Protein, Human (Biotinylated, sf9, Flag, Avi) is the recombinant human-derived NTRK1/TrkA-I, expressed by Sf9 insect cells , with Avi, Flag labeled tag. ,

HY-P702653

	CAMK1 delta Protein, Human (sf9, GST) Calcium/calmodulin-dependent protein kinase Type 1D; CaM kinase I delta; CaM kinase ID; CaM-KI delta; CaMKI delta; CaMKID	Human	Sf9 insect cells
	CAMK1 delta Protein, Human (sf9, GST) is the recombinant human-derived CAMK1 delta, expressed by Sf9 insect cells , with GST labeled tag. The total length of CAMK1 delta Protein, Human (sf9, GST) is 384 a.a.,

HY-P701756

	PNCK Protein, Human (Sf9, GST) PNCK; Calcium/calmodulin-dependent protein kinase Type 1B; CaM kinase I beta; CaM kinase IB; CaM-KI beta; CaMKI-beta; Pregnancy up-regulated non-ubiquitously-expressed CaM kinase	Human	Sf9 insect cells
	The PNCK protein is a calcium/calmodulin-dependent protein kinase and a key component of the calcium-triggered signaling cascade. In vitro, PNCK exhibits the ability to phosphorylate CREB1 and SYN1/synapsin I, emphasizing its involvement in regulating cellular processes associated with these substrates. PNCK Protein, Human (Sf9, GST) is the recombinant human-derived PNCK protein, expressed by Sf9 insect cells , with GST tagged. The total length of PNCK Protein, Human (Sf9, GST) is 342 a.a., .

HY-P701757

	PNCK Protein, Human (Sf9, His, GST) PNCK; Calcium/calmodulin-dependent protein kinase Type 1B; CaM kinase I beta; CaM kinase IB; CaM-KI beta; CaMKI-beta; Pregnancy up-regulated non-ubiquitously-expressed CaM kinase	Human	Sf9 insect cells
	The PNCK protein is a calcium/calmodulin-dependent protein kinase and a key component of the calcium-triggered signaling cascade. In vitro, PNCK exhibits the ability to phosphorylate CREB1 and SYN1/synapsin I, emphasizing its involvement in regulating cellular processes associated with these substrates. PNCK Protein, Human (Sf9, His, GST) is the recombinant human-derived PNCK protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of PNCK Protein, Human (Sf9, His, GST) is 342 a.a., .

HY-P76191

	CAMKI gamma/CAMK1G Protein, Human (sf9, His, GST) Calcium/calmodulin-dependent protein kinase Type 1G; CaMKI gamma; CLICK III; CLICK3; VWS1	Human	Sf9 insect cells
	The CAMK1G protein is a calcium/calmodulin-dependent protein kinase and a key component of the proposed calcium-triggered signaling cascade. This kinase exhibits the ability to phosphorylate the transcription factor CREB1 in vitro, suggesting its involvement in regulating cellular processes related to gene expression and transcriptional control. CAMKI gamma/CAMK1G Protein, Human (sf9, His, GST) is the recombinant human-derived CAMKI gamma/CAMK1G protein, expressed by Sf9 insect cells , with His, GST labeled tag.

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HY-P81744

	Trk A Antibody (YA1489) NTRK1; MTC; TRK; TRKA; High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor Type 1; TRK1-transforming tyrosine kinase protein; Tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	Trk A Antibody (YA1489) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1489), targeting Trk A, with a predicted molecular weight of 87 kDa. Trk A Antibody (YA1489) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

HY-P82244

	Activin A Receptor Type IB Antibody (YA1989) ACVR1B; ACVRLK4; ALK4; Activin receptor Type-1B; Activin receptor Type IB; ACTR-IB; Activin receptor-like kinase 4; ALK-4; Serine/threonine-protein kinase receptor R2; SKR2	WB	Human, Mouse, Rat
	Activin A Receptor Type IB Antibody (YA1989) is a biotin-conjugated non-conjugated IgG antibody, targeting Activin A Receptor Type IB, with a predicted molecular weight of 57 kDa (observed band size: 57 kDa). Activin A Receptor Type IB Antibody (YA1989) can be used for WB experiment in human, mouse, rat background.

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