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UDP-GlcNAc

" in MedChemExpress (MCE) Product Catalog:

By Targets:	OGT (3) Bacterial (1) Biochemical Assay Reagents (2) Endogenous Metabolite (3) Glycosyltransferase (1) Isotope-Labeled Compounds (1) Potassium Channel (1) Ser/Thr Protease (1)
By Research Areas:	Cancer (1) Endocrinology (1) Infection (1) Inflammation/Immunology (1) Metabolic Disease (7)
Click Chemistry:	Azide (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

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Recombinant Proteins

Isotope-Labeled Compounds

Click Chemistry

Targets Recommended: UGT OGA OGT

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-112174

UDP-GlcNAc disodium 4 Publications Verification UDP-α-D-N-Acetylglucosamine disodium	OGT	Metabolic Disease
UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a donor substrate of O-GlcNAc transferase (OGT).

HY-112174S

UDP-GlcNAc-13C disodium UDP-α-D-N-Acetylglucosamine-¹³C disodium	Isotope-Labeled Compounds	Metabolic Disease
UDP-GlcNAc- ¹³C (disodium) is the ¹³C labeled UDP-GlcNAc Disodium Salt. UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a donor substrate of O-GlcNAc transferase (O[1][2].

HY-112942A

CMP-Sialic acid sodium salt 1 Publications Verification CMP-Neu5Ac sodium salt	Endogenous Metabolite	Metabolic Disease
CMP-Sialic acid (CMP-Neu5Ac) sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid sodium salt provides a substrate for Golgi sialyltransferases. CMP-Sialic acid sodium salt is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .

HY-E70025

N-Acetylglucosamine-1-P uridyltransferase, Homo sapien GlcNAc1pUT	Others	Others
N-acetylglucosamine-1-P uridyltransferase (AGX1) (EC 2.3.1.157) (GlcNAc1pUT) is a bifunctional acetyltransferase/uridyltransferase. N-acetylglucosamine-1-P uridyltransferase (AGX1) binds GlcNAc-1-P and UTP, and catalyzes an uridyltransfer reaction to synthesize UDP-GlcNAc. N-acetylglucosamine-1-P uridyltransferase (AGX1) is a bifunctional enzyme exclusive to prokaryotes .

HY-139793

UDP-glucosamine disodium	OGT Endogenous Metabolite	Metabolic Disease
UDP-glucosamine (UDP-GlcNAc) disodium is a substrate for O-GlcNAc transferase, which catalyzes the attachment of O-GlcNAc to proteins. O-GlcNAcase catalyzes the removal of O-GlcNAc from proteins. UDP-glucosamine (UDP-GlcNAc) disodium is the end product of the hexosamine biosynthesis pathway, which is regulated primarily by glucose-6-phosphate-Glutamine:fructose-6-phosphate amidotransferase (GFAT) .

HY-E70286

N-Acetylglucosaminyltransferase V MGAT4B	Biochemical Assay Reagents	Cancer
N-Acetylglucosaminyltransferase V (MGAT4B) is the enzyme that catalyzes the formation of the β1,6-GlcNAc branch of N-glycans in the Golgi apparatus using UDP-GlcNAc as the donor substrate. N-Acetylglucosaminyltransferase V is involved in cancer malignancy and autoimmune disease etiology .

HY-112942

CMP-Sialic acid CMP-Neu5Ac	Endogenous Metabolite	Metabolic Disease
CMP-Sialic acid (CMP-Neu5Ac) is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid provides a substrate for Golgi sialyltransferases. CMP-Sialic acid is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .

HY-E70067

GlcNAc 1-P uridyltransferase (PmGlmU)	Others	Others
GlcNAc 1-P uridyltransferase (PmGlmU) catalyzes high efficient synthesis of UDP-GlcNAc from GlcNAc-1-P and UTP. GlcNAc 1-P uridyltransferase (PmGlmU) is used to break down the pyrophosphate formed in the PmGlmU reaction to inorganic phosphate to shift the equilibrium of the coupled enzymatic reactions towards the formation of UDP-GlcNA .

HY-E70044

beta-1, 3-N-Acetylhexaminyltransferase (LgtA)	Glycosyltransferase	Metabolic Disease
beta-1, 3-N-Acetylhexaminyltransferase (LgtA) is a glycosyltransferase, is often used in biochemical studies. beta-1, 3-N-Acetylhexaminyltransferase (LgtA) catalyzes the transfer of N-acetylglucosamine from UDP-GlcNAc to N-acetyllactosamine and lactose .

HY-E70030

GlcNAc 1-P uridyltransferase (CjGlmU)	Bacterial	Infection
GlcNAc 1-P uridyltransferase (CjGlmU) is a sugar nucleotidyltransferase (SNT). GlcNAc 1-P uridyltransferase (CjGlmU) utilizes UTP and GlcNAc-1-P as its natural substrates, synthesizes UDP-GlcNAc. GlcNAc 1-P uridyltransferase (CjGlmU) has the potential for the research of antimicrobial agents .

HY-145934A

UDP-GlcNAz disodium	OGT Biochemical Assay Reagents	Metabolic Disease
UDP-GlcNAz disodium is a substrate for UDP-GlcNAc:polypeptidyltransferase . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-P10572

HG1 Toxin	Ser/Thr Protease Potassium Channel	Inflammation/Immunology Endocrinology
HG1 Toxin is a peptide found in the venom of the scorpion Heterometrus fulvipes, which has the activity of inhibiting potassium channel Kv1.3. HG1 Toxin also has the activity of inhibiting trypsin (K_i=107 nM) and can be used in the study of autoimmune diseases .

Cat. No.	Product Name	Type

HY-145934A

UDP-GlcNAz disodium	Gene Sequencing and Synthesis
UDP-GlcNAz disodium is a substrate for UDP-GlcNAc:polypeptidyltransferase . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Cat. No.	Product Name	Target	Research Area

HY-P5375

*O-Linked GlcNAc* transferase substrate**	Peptides	Others
O-Linked GlcNAc transferase substrate is a biological active peptide. (A peptide substrate of O-linked GlcNAc transferase (OGT), a eukaryotic glycosyltransferase that uses UDP-GlcNAc as a glycosyl donor.)

HY-P5747

Glycocin F	Peptides	Others
Glycocin F is a antimicrobial peptide with activity against L. plantarum .

HY-P4752

*KWKHGAEIVYKSPVV-{S(GlcNAc-β-D)}-GDTSPRHLSNVK-{K(biotinyl)}-NH2*	Peptides	Others
KWKHGAEIVYKSPVV-{S(GlcNAc-β-D)}-GDTSPRHLSNVK-{K(biotinyl)}-NH2 is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P10572

HG1 Toxin	Ser/Thr Protease Potassium Channel	Inflammation/Immunology Endocrinology
HG1 Toxin is a peptide found in the venom of the scorpion Heterometrus fulvipes, which has the activity of inhibiting potassium channel Kv1.3. HG1 Toxin also has the activity of inhibiting trypsin (K_i=107 nM) and can be used in the study of autoimmune diseases .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-112942A

CMP-Sialic acid sodium salt 1 Publications Verification CMP-Neu5Ac sodium salt	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
CMP-Sialic acid (CMP-Neu5Ac) sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid sodium salt provides a substrate for Golgi sialyltransferases. CMP-Sialic acid sodium salt is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .

HY-139793

UDP-glucosamine disodium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	OGT Endogenous Metabolite
UDP-glucosamine (UDP-GlcNAc) disodium is a substrate for O-GlcNAc transferase, which catalyzes the attachment of O-GlcNAc to proteins. O-GlcNAcase catalyzes the removal of O-GlcNAc from proteins. UDP-glucosamine (UDP-GlcNAc) disodium is the end product of the hexosamine biosynthesis pathway, which is regulated primarily by glucose-6-phosphate-Glutamine:fructose-6-phosphate amidotransferase (GFAT) .

HY-112942

CMP-Sialic acid CMP-Neu5Ac	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
CMP-Sialic acid (CMP-Neu5Ac) is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid provides a substrate for Golgi sialyltransferases. CMP-Sialic acid is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .

Cat. No.	Compare	Product Name	Species	Source

HY-P71221

	POMGNT1 Protein, Human (HEK293, His) Protein O-Linked-Mannose Beta-1; 2-N-Acetylglucosaminyltransferase 1; POMGnT1; UDP-GlcNAc:Alpha-D-Mannoside Beta-1; 2-N-Acetylglucosaminyltransferase I.2; POMGNT1; MGAT1.2	Human	HEK293
	The POMGNT1 protein crucially directs O-mannosyl glycosylation, which adds N-acetylglucosamine to O-linked mannose residues on glycoproteins. It catalyzes GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr on α-dystroglycan and other O-mannosylated proteins, laying the foundation for subsequent carbohydrate addition. POMGNT1 Protein, Human (HEK293, His) is the recombinant human-derived POMGNT1 protein, expressed by HEK293 , with C-6*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-112174S

UDP-GlcNAc-13C disodium
UDP-GlcNAc- ¹³C (disodium) is the ¹³C labeled UDP-GlcNAc Disodium Salt. UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a donor substrate of O-GlcNAc transferase (O[1][2].

Cat. No.	Product Name		Classification

HY-145934A

UDP-GlcNAz disodium		Azide
UDP-GlcNAz disodium is a substrate for UDP-GlcNAc:polypeptidyltransferase . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

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UDP-GlcNAc

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Click Chemistry

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