UDP-GlcNAz disodium

Name: UDP-GlcNAz disodium
Brand: MedChemExpress
SKU: HY-145934A
Rating: 4.5 (1 reviews)

Cat. No.: HY-145934A Purity: 98.93%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

UDP-GlcNAz disodium is a substrate for UDP-GlcNAc:polypeptidyltransferase. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

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UDP-GlcNAz disodium Chemical Structure

CAS No. : 1611490-64-2

Size	Price	Stock	Quantity
5 mg	USD 380	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 680	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of UDP-GlcNAz disodium:

UDP-GalNAz disodium Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

UDP-GlcNAz disodium is a substrate for UDP-GlcNAc:polypeptidyltransferase^[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

Molecular Weight

692.33

Formula

C₁₇H₂₄N₆Na₂O₁₇P₂

CAS No.

1611490-64-2

Appearance

Solid

Color

White to off-white

SMILES

O=C(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3NC(CN=[N+]=[N-])=O)(O[Na])=O)(O[Na])=O)O2)NC1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

H₂O : 125 mg/mL (180.55 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.4444 mL	7.2220 mL	14.4440 mL
5 mM	0.2889 mL	1.4444 mL	2.8888 mL
10 mM	0.1444 mL	0.7222 mL	1.4444 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.93%

Select Batch:

Data Sheet (275 KB) SDS (252 KB)

COA (254 KB) HNMR (305 KB) RP-HPLC (247 KB) MS (68 KB)

Handling Instructions (2659 KB)

References

[1]. Vocadlo DJ, et, al. A chemical approach for identifying O-GlcNAc-modified proteins in cells. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9116-21. [Content Brief]

[2]. Kim EJ, et al. Versatile O-GlcNAc transferase assay for high-throughput identification of enzyme variants, substrates, and inhibitors. Bioconjug Chem. 2014 Jun 18;25(6):1025-30. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.4444 mL	7.2220 mL	14.4440 mL	36.1099 mL
	5 mM	0.2889 mL	1.4444 mL	2.8888 mL	7.2220 mL
	10 mM	0.1444 mL	0.7222 mL	1.4444 mL	3.6110 mL
	15 mM	0.0963 mL	0.4815 mL	0.9629 mL	2.4073 mL
	20 mM	0.0722 mL	0.3611 mL	0.7222 mL	1.8055 mL
	25 mM	0.0578 mL	0.2889 mL	0.5778 mL	1.4444 mL
	30 mM	0.0481 mL	0.2407 mL	0.4815 mL	1.2037 mL
	40 mM	0.0361 mL	0.1805 mL	0.3611 mL	0.9027 mL
	50 mM	0.0289 mL	0.1444 mL	0.2889 mL	0.7222 mL
	60 mM	0.0241 mL	0.1204 mL	0.2407 mL	0.6018 mL
	80 mM	0.0181 mL	0.0903 mL	0.1805 mL	0.4514 mL
	100 mM	0.0144 mL	0.0722 mL	0.1444 mL	0.3611 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.