2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. CMP-Sialic acid sodium salt

CMP-Sialic acid sodium salt  (Synonyms: CMP-Neu5Ac sodium salt)

Cat. No.: HY-112942A Purity: 92.51%
COA Handling Instructions

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CMP-Sialic acid (CMP-Neu5Ac) sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid sodium salt provides a substrate for Golgi sialyltransferases. CMP-Sialic acid sodium salt is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates.

For research use only. We do not sell to patients.

CMP-Sialic acid sodium salt Chemical Structure

CMP-Sialic acid sodium salt Chemical Structure

CAS No. : 1007117-62-5

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1 mg USD 55 In-stock
5 mg USD 160 In-stock
10 mg USD 275 In-stock
25 mg USD 576 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of CMP-Sialic acid sodium salt:

CMP-Sialic acid sodium salt Related Antibodies

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Description

CMP-Sialic acid (CMP-Neu5Ac) sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid sodium salt provides a substrate for Golgi sialyltransferases. CMP-Sialic acid sodium salt is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates[1].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

CMP-Sialic acid sodium salt (22.5 μM, 45 min) can be used as a CMAH substrate to detect the formation of Neu5Gc in platelet lysates[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CMP-Sialic acid sodium salt Related Antibodies
Molecular Weight

636.43

Formula

C20H30N4NaO16P
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@@H]1[C@H](O[C@@H](N2C(N=C(N)C=C2)=O)[C@@H]1O)COP(O[C@@]3(O[C@@]([C@H](NC(C)=O)[C@@H](O)C3)([H])[C@H](O)[C@H](O)CO)C(O)=O)(O[Na])=O
Structure Classification
Initial Source
Shipping

Shipping with dry ice.
Storage

-80°C
Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (196.41 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5713 mL 7.8563 mL 15.7126 mL
5 mM 0.3143 mL 1.5713 mL 3.1425 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 92.51%

COA (253 KB) HNMR (298 KB) RP-HPLC (264 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months. When stored at -80°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.5713 mL 7.8563 mL 15.7126 mL 39.2816 mL
5 mM 0.3143 mL 1.5713 mL 3.1425 mL 7.8563 mL
10 mM 0.1571 mL 0.7856 mL 1.5713 mL 3.9282 mL
15 mM 0.1048 mL 0.5238 mL 1.0475 mL 2.6188 mL
20 mM 0.0786 mL 0.3928 mL 0.7856 mL 1.9641 mL
25 mM 0.0629 mL 0.3143 mL 0.6285 mL 1.5713 mL
30 mM 0.0524 mL 0.2619 mL 0.5238 mL 1.3094 mL
40 mM 0.0393 mL 0.1964 mL 0.3928 mL 0.9820 mL
50 mM 0.0314 mL 0.1571 mL 0.3143 mL 0.7856 mL
60 mM 0.0262 mL 0.1309 mL 0.2619 mL 0.6547 mL
80 mM 0.0196 mL 0.0982 mL 0.1964 mL 0.4910 mL
100 mM 0.0157 mL 0.0786 mL 0.1571 mL 0.3928 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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CMP-Sialic acid sodium salt Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CMP-Sialic acid1007117-62-5CMP-Neu5AcEndogenous MetaboliteUDP-GlcNAc 2-epimerasesialicacidGolgisialyltransferasessugardonornucleotidesubstrateInhibitorinhibitorinhibit

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