Search Result
Results for "
chromogenic pNA substrate
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-P0021A
-
Spectrozyme PCa; Chromozym Pca diacetate
|
Fluorescent Dye
|
Others
|
D-Lys(Z)-Pro-Arg-pNA diacetate (Spectrozyme PCa) is a chromogenic substrate.
|
-
-
- HY-P10083
-
-
-
- HY-P10094
-
|
Fluorescent Dye
|
Others
|
β-Ala-Gly-Arg-pNA is a chromogenic substrate of thrombin with pNA a strong absorbance at 405 nm .
|
-
-
- HY-P10448
-
-
-
- HY-P3936
-
|
Fluorescent Dye
|
Others
|
Endotoxin Substrate (Boc-LGR-pNA) is a chromogenic substrate can be used in quantitative assays of endotoxin .
|
-
-
- HY-P4458
-
|
Ser/Thr Protease
|
Cancer
|
Boc-QAR-pNA is a chromogenic substrate of trypsin. Boc-QAR-pNA can be used to test trypsin activity .
|
-
-
- HY-P4460
-
|
Ser/Thr Protease
|
Cancer
|
AAA-pNA is a chromogenic substrate of Tripeptidyl-peptidase II. AAA-pNA can be used to test Tripeptidyl-peptidase II activity .
|
-
-
- HY-P4482
-
|
Bacterial
|
Infection
|
Suc-AAPE-pNA is a chromogenic substrate of glutamyl endopeptidase. Suc-AAPE-pNA can be used to test glutamyl endopeptidase activity .
|
-
-
- HY-138152
-
Benzyl-D-Arg-Gly-Arg-pNA dihydrochloride
|
Fluorescent Dye
|
Others
|
Z-D-Arg-Gly-Arg-pNA dihydrochloride is a hydrolytic chromogenic plasmin substrate .
|
-
-
- HY-P4464
-
|
Ser/Thr Protease
|
Cancer
|
Ala-Phe-Pro-pNA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA can be used to test tripeptidyl peptidase activity .
|
-
-
- HY-P4470
-
|
Ser/Thr Protease
|
Cancer
|
Phe-Pro-Ala-pNA is a chromogenic substrate of tripeptidyl peptidase. Phe-Pro-Ala-pNA can be used to test tripeptidyl peptidase activity .
|
-
-
- HY-P4518
-
|
Ser/Thr Protease
|
Others
|
Z-Val-Gly-Arg-pNA is a chromogenic substrate for urokinase. Z-Val-Gly-Arg-pNA can be used for determination of urokinase activity .
|
-
-
- HY-122142
-
|
Fluorescent Dye
|
Others
|
Pyr-Pro-Arg-pNA is a chromogenic substrate, which can be used for protein C determination .
|
-
-
- HY-P4475
-
-
-
- HY-P3126
-
|
Factor Xa
|
Others
|
Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a factor Xa specific chromogenic substrate .
|
-
-
- HY-P4453
-
|
Caspase
|
Cancer
|
Boc-Ala-Ala-Asp-pNA is a chromogenic substrate of granzyme B. Boc-Ala-Ala-Asp-pNA can be used to test functional activity of granzyme B .
|
-
-
- HY-P6027A
-
|
Fluorescent Dye
|
Others
|
H-D-CHA-Ala-Arg-pNA (diacetate) is the diacetate form of H-D-CHA-Ala-Arg-pNA (HY-150523). H-D-CHA-Ala-Arg-pNA (diacetate) is a chromogenic substrate for the amidolytic assay .
|
-
-
- HY-P2685
-
|
Fluorescent Dye
|
Others
|
MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive chromogenic substrate for human leukocyte and porcine pancreatic elastase .
|
-
-
- HY-137895
-
H-Arg-pNA 2HCl, 98%
|
Biochemical Assay Reagents
|
Others
|
L-Arginine p-nitroanilide dihydrochloride, 98% (H-Arg-pNA 2HCl, 98%) is a chromogenic substrate for cathepsin H and aminopeptidases.
|
-
-
- HY-119244
-
|
Dipeptidyl Peptidase
|
Others
|
Gly-Pro-pNA hydrochloride is a chromogenic substrate that can be cleaved by the circulating enzyme, dipeptidyl peptidase IV (DPP IV). Gly-Pro-pNA can be used to screen for DPP IV inhibitors .
|
-
-
- HY-153829
-
-
-
- HY-P4202
-
Suc-AEPF-pNA
|
Biochemical Assay Reagents
|
Others
|
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
|
-
-
- HY-138143
-
Chromozym-TH
|
Fluorescent Dye
|
Others
|
N-(p-Tosyl)-GPR-pNA acetate (Chromozym-TH) is a chromogenic substrate targeting the synthetic peptides Hirunorm IV and Hirunorm V and can be used to detect the dissociation constants (KI) of both peptides. Hirunorm IV and Hirunorm V are reversible inhibitors of amidolytic thrombin activity. By varying the peptide concentration at a fixed concentration of the chromogenic substrate N-(p-Tosyl)-GPR-pNA acetate, the dissociation constants determined were 0.134 nM (Hirunorm IV) and 0.245 nM (Hirunorm V) .
|
-
-
- HY-P4202A
-
Suc-AEPF-pNA TFA
|
Biochemical Assay Reagents
|
Others
|
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA ) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
|
-
-
- HY-123275A
-
S-2238 hydrochloride
|
Fluorescent Dye
|
Others
|
H-D-Phe-Pip-Arg-pNA (S-2238) hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform .
|
-
-
- HY-123275
-
S-2238
|
Fluorescent Dye
|
Others
|
H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform .
|
-
-
- HY-123275C
-
S-2238 dihydrochloride
|
Fluorescent Dye
|
Others
|
H-D-Phe-Pip-Arg-pNA (S-2238) dihydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA dihydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA dihydrochloride is sensitive, accurate, and easy to perform .
|
-
-
- HY-123275B
-
S-2238 acetate
|
Fluorescent Dye
|
Others
|
H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform .
|
-
-
- HY-P4039
-
|
HCV Protease
|
Infection
|
Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein .
|
-
-
- HY-P10668
-
|
Dengue virus
Flavivirus
|
Infection
|
Ac-EVKKQR-pNA is a competitive chromogenic para-nitroanilide substrate corresponding to the P6-P1 segment amino-terminal to the NS2B-NS3 cleavage site but with a more reactive, hydrolytically cleavable, para-nitroanilide at the P1’ position. Ac-EVKKQR-pNA is promising for research of dengue 2 virus and flavivirus virus infection .
|
-
-
- HY-P3480
-
|
Fluorescent Dye
|
Others
|
H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA is a chromogenic substrate for Pin1. Pin1 is an essential and conserved mitotic peptidyl-prolyl isomerase, and can recognize the phosphoserine-proline bonds present in mitotic phosphoproteins .
|
-
-
- HY-137798
-
|
Fluorescent Dye
|
Others
|
Chromozym PL is a chromogenic substrate for plasmin, and the enzymatic reaction can be carried out in 0.1mL Tris-HCl buffer (50 mM, pH 7.8). 100 μM Chromozym PL was dissolved and prepared. After adding the hydrolase, the generation of p-nitroaniline (pNA) at 405 nm was continuously observed, and the hydrolysis products were calculated .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-P0021A
-
Spectrozyme PCa; Chromozym Pca diacetate
|
Chromogenic Substrates
|
D-Lys(Z)-Pro-Arg-pNA diacetate (Spectrozyme PCa) is a chromogenic substrate.
|
-
- HY-P2685
-
|
Chromogenic Substrates
|
MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive chromogenic substrate for human leukocyte and porcine pancreatic elastase .
|
-
- HY-P4202
-
Suc-AEPF-pNA
|
Chromogenic Substrates
|
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
|
-
- HY-P4202A
-
Suc-AEPF-pNA TFA
|
Chromogenic Substrates
|
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA ) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
|
-
- HY-P4039
-
|
Chromogenic Substrates
|
Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein .
|
Cat. No. |
Product Name |
Type |
-
- HY-137895
-
H-Arg-pNA 2HCl, 98%
|
Enzyme Substrates
|
L-Arginine p-nitroanilide dihydrochloride, 98% (H-Arg-pNA 2HCl, 98%) is a chromogenic substrate for cathepsin H and aminopeptidases.
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P2573
-
Suc-Ala-Ala-Pro-Phe-pNA
|
Peptides
|
Others
|
Suc-AAPF-pNA (Suc-Ala-Ala-Pro-Phe-pNA) is a chromogenic p-nitroanilide (pNA) substrate with the Km of 1.7 mM. Cleavage of Suc-AAPF-pNA releases 4-nitroaniline, which is yellow in colour and can be measured spectrophotometrically. Suc-AAPF-pNA can be used for the measurement of free and membrane-bound cathepsin G in human neutrophils .
|
-
- HY-P0021A
-
Spectrozyme PCa; Chromozym Pca diacetate
|
Fluorescent Dye
|
Others
|
D-Lys(Z)-Pro-Arg-pNA diacetate (Spectrozyme PCa) is a chromogenic substrate.
|
-
- HY-P10083
-
-
- HY-P10094
-
|
Fluorescent Dye
|
Others
|
β-Ala-Gly-Arg-pNA is a chromogenic substrate of thrombin with pNA a strong absorbance at 405 nm .
|
-
- HY-P10448
-
-
- HY-P3936
-
|
Fluorescent Dye
|
Others
|
Endotoxin Substrate (Boc-LGR-pNA) is a chromogenic substrate can be used in quantitative assays of endotoxin .
|
-
- HY-P4458
-
|
Ser/Thr Protease
|
Cancer
|
Boc-QAR-pNA is a chromogenic substrate of trypsin. Boc-QAR-pNA can be used to test trypsin activity .
|
-
- HY-P4460
-
|
Ser/Thr Protease
|
Cancer
|
AAA-pNA is a chromogenic substrate of Tripeptidyl-peptidase II. AAA-pNA can be used to test Tripeptidyl-peptidase II activity .
|
-
- HY-P4482
-
|
Bacterial
|
Infection
|
Suc-AAPE-pNA is a chromogenic substrate of glutamyl endopeptidase. Suc-AAPE-pNA can be used to test glutamyl endopeptidase activity .
|
-
- HY-P6027
-
|
Peptides
|
Others
|
H-D-CHA-Ala-Arg-pNA is a chromogenic substrate for the amidolytic assay .
|
-
- HY-138152
-
Benzyl-D-Arg-Gly-Arg-pNA dihydrochloride
|
Fluorescent Dye
|
Others
|
Z-D-Arg-Gly-Arg-pNA dihydrochloride is a hydrolytic chromogenic plasmin substrate .
|
-
- HY-P4464
-
|
Ser/Thr Protease
|
Cancer
|
Ala-Phe-Pro-pNA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA can be used to test tripeptidyl peptidase activity .
|
-
- HY-P4470
-
|
Ser/Thr Protease
|
Cancer
|
Phe-Pro-Ala-pNA is a chromogenic substrate of tripeptidyl peptidase. Phe-Pro-Ala-pNA can be used to test tripeptidyl peptidase activity .
|
-
- HY-P4518
-
|
Ser/Thr Protease
|
Others
|
Z-Val-Gly-Arg-pNA is a chromogenic substrate for urokinase. Z-Val-Gly-Arg-pNA can be used for determination of urokinase activity .
|
-
- HY-P4475
-
-
- HY-P4484
-
|
Peptides
|
Others
|
Suc-AAPK-pNA is a chromogenic substrate for the determination of serine/threonine kinase activity and enzyme kinetic parameters .
|
-
- HY-P3126
-
|
Factor Xa
|
Others
|
Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a factor Xa specific chromogenic substrate .
|
-
- HY-P4453
-
|
Caspase
|
Cancer
|
Boc-Ala-Ala-Asp-pNA is a chromogenic substrate of granzyme B. Boc-Ala-Ala-Asp-pNA can be used to test functional activity of granzyme B .
|
-
- HY-P4517
-
|
Peptides
|
Others
|
Z-Tyr-Lys-Arg-pNA is a chromogenic substrate. Z-Tyr-Lys-Arg-pNA can be used to detect the activity of subtilisin-type and yapsin-like proteases .
|
-
- HY-P6027A
-
|
Fluorescent Dye
|
Others
|
H-D-CHA-Ala-Arg-pNA (diacetate) is the diacetate form of H-D-CHA-Ala-Arg-pNA (HY-150523). H-D-CHA-Ala-Arg-pNA (diacetate) is a chromogenic substrate for the amidolytic assay .
|
-
- HY-P2685
-
|
Fluorescent Dye
|
Others
|
MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive chromogenic substrate for human leukocyte and porcine pancreatic elastase .
|
-
- HY-P10145
-
|
Peptides
|
Others
|
Ac-LEVD-pNA is a chromogenic substrate for caspase-4 and can be used to detect caspase-4 activity .
|
-
- HY-P4491
-
|
Peptides
|
Others
|
Suc-Leu-Leu-Val-Tyr-pNA is a chymotrypsin-like chromogenic substrate that can be used to detect chymotrypsin enzymatic activity .
|
-
- HY-P10005
-
|
Peptides
|
Cardiovascular Disease
|
D-Val-Gly-Arg-pNA is a chromogenic substrate of TPA (tissue plasminogen activator). D-Val-Gly-Arg-pNA can be used to detect the amidolytic activity of TPA I and TPA II .
|
-
- HY-P4516
-
|
Peptides
|
Cancer
|
Z-Phe-Leu-Glu-pNA is a chromogenic substrate for glutamyl endopeptidases. Z-Phe-Leu-Glu-pNA has been used as a synthetic substrate in the study of proteolytic enzymes, including trypsin treatment, subtilisin and chymotrypsin. Z-Phe-Leu-Glu-pNA plays an important role in hormone disorders such as prostate cancer and breast cancer .
|
-
- HY-P4202
-
Suc-AEPF-pNA
|
Biochemical Assay Reagents
|
Others
|
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
|
-
- HY-P4202A
-
Suc-AEPF-pNA TFA
|
Biochemical Assay Reagents
|
Others
|
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA ) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .
|
-
- HY-123275A
-
S-2238 hydrochloride
|
Fluorescent Dye
|
Others
|
H-D-Phe-Pip-Arg-pNA (S-2238) hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform .
|
-
- HY-123275
-
S-2238
|
Fluorescent Dye
|
Others
|
H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform .
|
-
- HY-123275C
-
S-2238 dihydrochloride
|
Fluorescent Dye
|
Others
|
H-D-Phe-Pip-Arg-pNA (S-2238) dihydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA dihydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA dihydrochloride is sensitive, accurate, and easy to perform .
|
-
- HY-123275B
-
S-2238 acetate
|
Fluorescent Dye
|
Others
|
H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform .
|
-
- HY-P4039
-
|
HCV Protease
|
Infection
|
Ac-EEVVAC-pNA is a chromogenic substrate for a continuous spectrophotometric assay of HCV NS3 protease. The sequence EEVVAC is derived from the 5A-5B cleavage junction of the HCV polyprotein .
|
-
- HY-P10668
-
|
Dengue virus
Flavivirus
|
Infection
|
Ac-EVKKQR-pNA is a competitive chromogenic para-nitroanilide substrate corresponding to the P6-P1 segment amino-terminal to the NS2B-NS3 cleavage site but with a more reactive, hydrolytically cleavable, para-nitroanilide at the P1’ position. Ac-EVKKQR-pNA is promising for research of dengue 2 virus and flavivirus virus infection .
|
-
- HY-P3480
-
|
Fluorescent Dye
|
Others
|
H-Trp-Phe-Tyr-Ser(PO3H2)-Pro-Arg-pNA is a chromogenic substrate for Pin1. Pin1 is an essential and conserved mitotic peptidyl-prolyl isomerase, and can recognize the phosphoserine-proline bonds present in mitotic phosphoproteins .
|
-
- HY-137798
-
|
Fluorescent Dye
|
Others
|
Chromozym PL is a chromogenic substrate for plasmin, and the enzymatic reaction can be carried out in 0.1mL Tris-HCl buffer (50 mM, pH 7.8). 100 μM Chromozym PL was dissolved and prepared. After adding the hydrolase, the generation of p-nitroaniline (pNA) at 405 nm was continuously observed, and the hydrolysis products were calculated .
|
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