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  6. Z-Phe-Leu-Glu-pNA

Z-Phe-Leu-Glu-pNA is a chromogenic substrate for glutamyl endopeptidases. Z-Phe-Leu-Glu-pNA has been used as a synthetic substrate in the study of proteolytic enzymes, including trypsin treatment, subtilisin and chymotrypsin. Z-Phe-Leu-Glu-pNA plays an important role in hormone disorders such as prostate cancer and breast cancer.

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Custom Peptide Synthesis

Z-Phe-Leu-Glu-pNA Chemical Structure

Z-Phe-Leu-Glu-pNA Chemical Structure

CAS No. : 104634-10-8

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Z-Phe-Leu-Glu-pNA Related Antibodies

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Description

Z-Phe-Leu-Glu-pNA is a chromogenic substrate for glutamyl endopeptidases. Z-Phe-Leu-Glu-pNA has been used as a synthetic substrate in the study of proteolytic enzymes, including trypsin treatment, subtilisin and chymotrypsin. Z-Phe-Leu-Glu-pNA plays an important role in hormone disorders such as prostate cancer and breast cancer[1][2].

IC50 & Target

others
Molecular Weight

661.70

Formula

C34H39N5O9
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Z-Phe-Leu-{Glu-pNA}
Sequence Shortening

Z-FL-{Glu-pNA}
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (75.56 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5113 mL 7.5563 mL 15.1126 mL
5 mM 0.3023 mL 1.5113 mL 3.0225 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5113 mL 7.5563 mL 15.1126 mL 37.7815 mL
5 mM 0.3023 mL 1.5113 mL 3.0225 mL 7.5563 mL
10 mM 0.1511 mL 0.7556 mL 1.5113 mL 3.7781 mL
15 mM 0.1008 mL 0.5038 mL 1.0075 mL 2.5188 mL
20 mM 0.0756 mL 0.3778 mL 0.7556 mL 1.8891 mL
25 mM 0.0605 mL 0.3023 mL 0.6045 mL 1.5113 mL
30 mM 0.0504 mL 0.2519 mL 0.5038 mL 1.2594 mL
40 mM 0.0378 mL 0.1889 mL 0.3778 mL 0.9445 mL
50 mM 0.0302 mL 0.1511 mL 0.3023 mL 0.7556 mL
60 mM 0.0252 mL 0.1259 mL 0.2519 mL 0.6297 mL
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Z-Phe-Leu-Glu-pNA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Z-Phe-Leu-Glu-pNA104634-10-8OthersGlutamyl EndopeptidasesCancerInhibitorinhibitorinhibit

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