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  4. Suc-Ala-Glu-Pro-Phe-pNA

Suc-Ala-Glu-Pro-Phe-pNA  (Synonyms: Suc-AEPF-pNA)

Cat. No.: HY-P4202 Purity: 98.52%
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Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Suc-Ala-Glu-Pro-Phe-pNA Chemical Structure

Suc-Ala-Glu-Pro-Phe-pNA Chemical Structure

CAS No. : 128802-76-6

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1 mg USD 50 In-stock
5 mg USD 110 In-stock
10 mg USD 180 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Suc-Ala-Glu-Pro-Phe-pNA:

Suc-Ala-Glu-Pro-Phe-pNA Related Antibodies

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Description

Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc[1][2].

Molecular Weight

682.68

Formula

C32H38N6O11
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

{Suc}-Ala-Glu-Pro-Phe-{pNA}
Sequence Shortening

{Suc}-AEPF-{pNA}
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (183.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4648 mL 7.3241 mL 14.6482 mL
5 mM 0.2930 mL 1.4648 mL 2.9296 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4648 mL 7.3241 mL 14.6482 mL 36.6204 mL
5 mM 0.2930 mL 1.4648 mL 2.9296 mL 7.3241 mL
10 mM 0.1465 mL 0.7324 mL 1.4648 mL 3.6620 mL
15 mM 0.0977 mL 0.4883 mL 0.9765 mL 2.4414 mL
20 mM 0.0732 mL 0.3662 mL 0.7324 mL 1.8310 mL
25 mM 0.0586 mL 0.2930 mL 0.5859 mL 1.4648 mL
30 mM 0.0488 mL 0.2441 mL 0.4883 mL 1.2207 mL
40 mM 0.0366 mL 0.1831 mL 0.3662 mL 0.9155 mL
50 mM 0.0293 mL 0.1465 mL 0.2930 mL 0.7324 mL
60 mM 0.0244 mL 0.1221 mL 0.2441 mL 0.6103 mL
80 mM 0.0183 mL 0.0916 mL 0.1831 mL 0.4578 mL
100 mM 0.0146 mL 0.0732 mL 0.1465 mL 0.3662 mL
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Suc-Ala-Glu-Pro-Phe-pNA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Suc-Ala-Glu-Pro-Phe-pNA128802-76-6Suc-AEPF-pNABiochemical Assay ReagentsChromogenicsubstratepeptidylprolyl isomeraseInhibitorinhibitorinhibit

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