Suc-Ala-Glu-Pro-Phe-pNA (Synonyms: Suc-AEPF-pNA)

Cat. No.: HY-P4202 Purity: 98.52%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Suc-Ala-Glu-Pro-Phe-pNA Chemical Structure

CAS No. : 128802-76-6

Size	Price	Stock	Quantity
5 mg	USD 110	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 180	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Suc-Ala-Glu-Pro-Phe-pNA:

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Description

Molecular Weight

682.68

Formula

C₃₂H₃₈N₆O₁₁

CAS No.

128802-76-6

Appearance

Solid

Color

White to off-white

Sequence

{Suc}-Ala-Glu-Pro-Phe-{pNA}

Sequence Shortening

{Suc}-AEPF-{pNA}

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (183.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.4648 mL	7.3241 mL	14.6482 mL
5 mM	0.2930 mL	1.4648 mL	2.9296 mL
10 mM	0.1465 mL	0.7324 mL	1.4648 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.52%

Select Batch:

Data Sheet (274 KB) SDS (252 KB)

COA (253 KB) RP-HPLC (111 KB) MS (203 KB) Elemental Analysis Report (113 KB)

Handling Instructions (2659 KB)

References

[1]. Subedi A, et al. Discovery of novel selenium derivatives as Pin1 inhibitors by high-throughput screening. Biochem Biophys Res Commun. 2016 Jun 3;474(3):528-533. [Content Brief]

[2]. Liu C, et al. Imazamethabenz inhibits human breast cancer cell proliferation, migration and invasion via combination with Pin1. Mol Med Rep. 2017 May;15(5):3210-3214. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.4648 mL	7.3241 mL	14.6482 mL	36.6204 mL
	5 mM	0.2930 mL	1.4648 mL	2.9296 mL	7.3241 mL
	10 mM	0.1465 mL	0.7324 mL	1.4648 mL	3.6620 mL
	15 mM	0.0977 mL	0.4883 mL	0.9765 mL	2.4414 mL
	20 mM	0.0732 mL	0.3662 mL	0.7324 mL	1.8310 mL
	25 mM	0.0586 mL	0.2930 mL	0.5859 mL	1.4648 mL
	30 mM	0.0488 mL	0.2441 mL	0.4883 mL	1.2207 mL
	40 mM	0.0366 mL	0.1831 mL	0.3662 mL	0.9155 mL
	50 mM	0.0293 mL	0.1465 mL	0.2930 mL	0.7324 mL
	60 mM	0.0244 mL	0.1221 mL	0.2441 mL	0.6103 mL
	80 mM	0.0183 mL	0.0916 mL	0.1831 mL	0.4578 mL
	100 mM	0.0146 mL	0.0732 mL	0.1465 mL	0.3662 mL

Suc-Ala-Glu-Pro-Phe-pNA Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Suc-Ala-Glu-Pro-Phe-pNA128802-76-6Suc-AEPF-pNABiochemical Assay ReagentsChromogenicsubstratepeptidylprolyl isomeraseInhibitorinhibitorinhibit

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Suc-Ala-Glu-Pro-Phe-pNA (Synonyms: Suc-AEPF-pNA)

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Other Forms of Suc-Ala-Glu-Pro-Phe-pNA:

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References

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Complete Stock Solution Preparation Table

Suc-Ala-Glu-Pro-Phe-pNA Related Classifications

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