Search Result
Results for "
dTTP
" in MedChemExpress (MCE) Product Catalog:
6
Biochemical Assay Reagents
8
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W013715A
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- HY-138615S1
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- HY-138615S2
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- HY-158715
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Biochemical Assay Reagents
DNA/RNA Synthesis
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Others
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3'-ONH2-dTTP sodium solution (100mM) is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
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- HY-138615
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- HY-138615A
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- HY-138615S3
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- HY-138615S4
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- HY-158707
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- HY-158676
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- HY-158672
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Biochemical Assay Reagents
DNA/RNA Synthesis
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Others
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3′-O-Azidomethyl-dTTP sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
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- HY-158716
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Biochemical Assay Reagents
DNA/RNA Synthesis
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Others
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3'-O-Methylthiomethyl-dTTP sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
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- HY-D1811
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VF 555-dUTP
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Fluorescent Dye
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Others
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Vari Fluor 555-dUTP (VF 555-dUTP) can be used to produce biotinylated DNA probes in a variety of assay applications by enzymatic incorporation into DNA/cDNA, replacing its natural counterpart, dTTP .
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- HY-D1810
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Fluorescent Dye
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Others
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Sulfo-Cy3-E-dUTP is enzymatically incorporated into DNA/cDNA as a substitute for its natural counterpart, dTTP. Sulfo-Cy3-E-dUTP can be used to produce biotinylated DNA probes for various detection applications .
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- HY-D1812
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VF 488-dUTP
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Fluorescent Dye
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Others
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Vari Fluor 488-dUTP (VF 488-dUTP) can replace its natural counterpart, dTTP, by enzymatic incorporation into DNA/cDNA. Vari Fluor 555-dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
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- HY-D1813
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VF 594-dUTP
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Fluorescent Dye
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Others
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Vari Fluor 594-dUTP (VF 594-dUTP) can replace its natural counterpart, dTTP, by enzymatic incorporation into DNA/cDNA. Vari Fluor 555-dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
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- HY-D1814
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VF 640-dUTP
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Fluorescent Dye
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Others
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Vari Fluor 640-dUTP (VF 640-dUTP) is enzymatically incorporated into DNA/cDNA and can replace its natural counterpart, dTTP. Vari Fluor 555-dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
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- HY-D1022
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Biotin-16-deoxyuridine-5'-triphosphate
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Fluorescent Dye
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Others
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Biotin-16-dUTP (Biotin-16-deoxyuridine-5'-triphosphate) can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
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- HY-D1022A
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Biotin-16-deoxyuridine-5'-triphosphate trisodium
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DNA Stain
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Others
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Biotin-16- dUTP (Biotin-16-deoxyuridine-5'-triphosphate) trisodium can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP trisodium can be used to produce biotinylated DNA probes in a variety of assay applications .
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- HY-D1029
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- HY-D1029A
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- HY-D1818
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Fluorescent Dye
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Others
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Vari Fluor 680-Phalloidin is a fluorescent derivative of Phalloidin that specifically labels myofilament proteins and exhibits red fluorescence when labeled at 680/700 nm .
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- HY-D1819
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Fluorescent Dye
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Others
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Vari Fluor 633-Phalloidin is a fluorescent derivative of Phalloidin that specifically labels myofilament proteins and exhibits red fluorescence at 630/650 nm when labeled .
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- HY-D1820
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Fluorescent Dye
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Others
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Vari Fluor 594-Phalloidin is a fluorescent derivative of Phalloidin that specifically labels myofilament proteins and exhibits red fluorescence at 585/609 nm when labeled .
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- HY-D1816
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Fluorescent Dye
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Others
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Vari Fluor 555-Phalloidin is a fluorescent derivative of Phalloidin that specifically labels myofilament proteins and exhibits red fluorescence when labeled, allowing for fluorescence imaging using the PE channel (Ex/Em=550 nm/561 nm) .
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- HY-D1817
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Fluorescent Dye
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Others
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Vari Fluor 488-Phalloidin is a fluorescent derivative of Phalloidin that specifically labels myofilament proteins and exhibits green fluorescence when labeled, allowing for fluorescence imaging using FITC channels (Ex/Em=488 nm/513 nm) .
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- HY-15353
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MKC-442
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HIV
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Infection
Inflammation/Immunology
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Emivirine (MKC-442) is a non-nucleoside reverse transcriptase inhibitors (NNRTIs) with Ki values of 0.20 and 0.01 μM for dTTP- and dGTP-dependent DNA or RNA polymerase activity, respectively. Emivirine displays potent and selective anti-human immunodeficiency virus type 1 (HIV-1) activity .
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- HY-90006
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5-FU
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Nucleoside Antimetabolite/Analog
HIV
Apoptosis
Endogenous Metabolite
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Cancer
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5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .
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- HY-131576
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dTDP
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Endogenous Metabolite
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Infection
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Thymidine 5′-diphosphate (dTDP) is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg 2+. Thymidine 5′-diphosphate is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate .
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- HY-131576A
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dTDP sodium
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Endogenous Metabolite
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Infection
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Thymidine 5′-diphosphate (dTDP) sodium is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate sodium is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg 2+. Thymidine 5′-diphosphate sodium is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate .
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- HY-90006S
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5-FU-d1
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Nucleoside Antimetabolite/Analog
HIV
Apoptosis
Endogenous Metabolite
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Cancer
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5-Fluorouracil-d is the deuterium labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[1][2]. 5-Fluorouracil also inhibits HIV[3].
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- HY-90006S2
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Nucleoside Antimetabolite/Analog
HIV
Apoptosis
Endogenous Metabolite
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Cancer
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5-Fluorouracil- 15N2 is the 15N-labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[1][2]. 5-Fluorouracil also inhibits HIV[3].
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- HY-90006R
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Nucleoside Antimetabolite/Analog
HIV
Apoptosis
Endogenous Metabolite
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Cancer
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5-Fluorouracil (Standard) is the analytical standard of 5-Fluorouracil. This product is intended for research and analytical applications. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer . 5-Fluorouracil also inhibits HIV .
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- HY-90006S1
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5-FU-13C,15N2
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Apoptosis
Nucleoside Antimetabolite/Analog
HIV
Endogenous Metabolite
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Cancer
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5-Fluorouracil- 13C, 15N2 is the 13C and 15N labeled 5-Fluorouracil[1]. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[2][3]. 5-Fluorouracil also inhibits HIV[4].
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- HY-90006S3
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5-FU-13C4,15N2
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Apoptosis
Nucleoside Antimetabolite/Analog
HIV
Endogenous Metabolite
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Cancer
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5-Fluorouracil- 13C4, 15N2 is the 13C and 15N labeled 5-Fluorouracil[1]. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[2][3]. 5-Fluorouracil also inhibits HIV[4].
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- HY-116973
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HIV
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Infection
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L-738372 is a non-competitive reversible inhibitor of HIV-1 reverse transcriptase (RT) with an inhibition constant (Ki) of 140 nM against dTTP. When combined with any nucleoside analogs (such as azidothymidine triphosphate, didexoyinosine triphosphate, or didexoycytidine triphosphate), L-738372 exhibits synergistic inhibition of RT activity. L-738372 has 2-3 times more inhibitory potency against the azidothymidine-resistant RT (D67N, K70R, T215Y, K219Q) compared to the wild-type RT. L-738372 holds promise for research in the field of HIV virus treatment .
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- HY-16638
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PDDF
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Thymidylate Synthase
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Metabolic Disease
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CB 3717 is a potent inhibitor of human thymidylate synthetase, competitively binding with 5,10-methylenetetrahydrofolate (Ki = 4.9 X 10(-9) M). It also competitively inhibits human dihydrofolate reductase with dihydrofolate (Ki = 2.3 X 10(-8) M). In WI-L2 human lymphoblastoid cells, CB 3717 treatment led to a significant decrease in cellular dTTP levels and a notable increase in dUMP levels, indicating a disruption in nucleotide metabolism. The growth-inhibitory effect of CB 3717 was reversed by thymidine supplementation, demonstrating that thymidylate synthetase became rate-limiting in the presence of this compound. Delayed thymidine supplementation beyond 8 hours resulted in severe cytotoxicity, underscoring the critical timing of nucleotide rescue strategies in CB 3717-treated cells .
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Cat. No. |
Product Name |
Type |
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- HY-D1811
-
VF 555-dUTP
|
Dyes
|
Vari Fluor 555-dUTP (VF 555-dUTP) can be used to produce biotinylated DNA probes in a variety of assay applications by enzymatic incorporation into DNA/cDNA, replacing its natural counterpart, dTTP .
|
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- HY-D1812
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VF 488-dUTP
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Dyes
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Vari Fluor 488-dUTP (VF 488-dUTP) can replace its natural counterpart, dTTP, by enzymatic incorporation into DNA/cDNA. Vari Fluor 555-dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
|
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- HY-D1813
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VF 594-dUTP
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Dyes
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Vari Fluor 594-dUTP (VF 594-dUTP) can replace its natural counterpart, dTTP, by enzymatic incorporation into DNA/cDNA. Vari Fluor 555-dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
|
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- HY-D1814
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VF 640-dUTP
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Dyes
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Vari Fluor 640-dUTP (VF 640-dUTP) is enzymatically incorporated into DNA/cDNA and can replace its natural counterpart, dTTP. Vari Fluor 555-dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
|
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- HY-D1022A
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Biotin-16-deoxyuridine-5'-triphosphate trisodium
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Fluorescent Dyes/Probes
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Biotin-16- dUTP (Biotin-16-deoxyuridine-5'-triphosphate) trisodium can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP trisodium can be used to produce biotinylated DNA probes in a variety of assay applications .
|
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- HY-D1029A
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-
- HY-D1818
-
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Dyes
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Vari Fluor 680-Phalloidin is a fluorescent derivative of Phalloidin that specifically labels myofilament proteins and exhibits red fluorescence when labeled at 680/700 nm .
|
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- HY-D1810
-
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Dyes
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Sulfo-Cy3-E-dUTP is enzymatically incorporated into DNA/cDNA as a substitute for its natural counterpart, dTTP. Sulfo-Cy3-E-dUTP can be used to produce biotinylated DNA probes for various detection applications .
|
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- HY-D1022
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Biotin-16-deoxyuridine-5'-triphosphate
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Fluorescent Dyes/Probes
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Biotin-16-dUTP (Biotin-16-deoxyuridine-5'-triphosphate) can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .
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- HY-D1029
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- HY-D1819
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Dyes
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Vari Fluor 633-Phalloidin is a fluorescent derivative of Phalloidin that specifically labels myofilament proteins and exhibits red fluorescence at 630/650 nm when labeled .
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- HY-D1820
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Dyes
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Vari Fluor 594-Phalloidin is a fluorescent derivative of Phalloidin that specifically labels myofilament proteins and exhibits red fluorescence at 585/609 nm when labeled .
|
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- HY-D1816
-
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Dyes
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Vari Fluor 555-Phalloidin is a fluorescent derivative of Phalloidin that specifically labels myofilament proteins and exhibits red fluorescence when labeled, allowing for fluorescence imaging using the PE channel (Ex/Em=550 nm/561 nm) .
|
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- HY-D1817
-
|
Dyes
|
Vari Fluor 488-Phalloidin is a fluorescent derivative of Phalloidin that specifically labels myofilament proteins and exhibits green fluorescence when labeled, allowing for fluorescence imaging using FITC channels (Ex/Em=488 nm/513 nm) .
|
Cat. No. |
Product Name |
Type |
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- HY-W013715A
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dTTP trisodium
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Gene Sequencing and Synthesis
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Deoxythymidine-5'-triphosphate (dTTP) trisodium is one of the four nucleoside triphosphates used in the synthesis of DNA .
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- HY-158715
-
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Gene Sequencing and Synthesis
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3'-ONH2-dTTP sodium solution (100mM) is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
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- HY-158707
-
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Gene Sequencing and Synthesis
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dTTPαS sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
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- HY-158676
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Gene Sequencing and Synthesis
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3'-P-dTTP sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
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- HY-158672
-
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Gene Sequencing and Synthesis
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3′-O-Azidomethyl-dTTP sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
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- HY-158716
-
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Gene Sequencing and Synthesis
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3'-O-Methylthiomethyl-dTTP sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-138615S1
-
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Deoxythymidine-5'-triphosphate- 15N2 (dTTP- 15N2) dilithium is 15N labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.
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- HY-138615S2
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Deoxythymidine-5'-triphosphate- 13C10 (dTTP- 13C10) dilithium is 13C-labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.
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- HY-90006S
-
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5-Fluorouracil-d is the deuterium labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[1][2]. 5-Fluorouracil also inhibits HIV[3].
|
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- HY-90006S2
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5-Fluorouracil- 15N2 is the 15N-labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[1][2]. 5-Fluorouracil also inhibits HIV[3].
|
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- HY-90006S1
-
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5-Fluorouracil- 13C, 15N2 is the 13C and 15N labeled 5-Fluorouracil[1]. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[2][3]. 5-Fluorouracil also inhibits HIV[4].
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- HY-138615S3
-
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Deoxythymidine-5'-triphosphate- 15N2,d15 (dTTP- 15N2,d15) dilithium is deuterium and 15N labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.
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- HY-138615S4
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Deoxythymidine-5'-triphosphate- 13C10, 15N2 (dTTP- 13C10, 15N2) dilithium is 13C and 15N-labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.
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- HY-90006S3
-
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5-Fluorouracil- 13C4, 15N2 is the 13C and 15N labeled 5-Fluorouracil[1]. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[2][3]. 5-Fluorouracil also inhibits HIV[4].
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Cat. No. |
Product Name |
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Classification |
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- HY-158672
-
|
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Azide
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3′-O-Azidomethyl-dTTP sodium is a labeled modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence and has special applications in gene synthesis and sequencing .
|
Cat. No. |
Product Name |
|
Classification |
-
- HY-W013715A
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dTTP trisodium
|
|
Nucleotides and their Analogs
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Deoxythymidine-5'-triphosphate (dTTP) trisodium is one of the four nucleoside triphosphates used in the synthesis of DNA .
|
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- HY-138615
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dTTP
|
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Nucleotides and their Analogs
|
Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA .
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- HY-138615A
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dTTP sodium hydrate
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Nucleotides and their Analogs
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Deoxythymidine-5'-triphosphate (dTTP) sodium hydrate is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate trisodium salt is used in the synthesis of DNA .
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