1. Cell Cycle/DNA Damage Anti-infection Apoptosis Metabolic Enzyme/Protease
  2. Nucleoside Antimetabolite/Analog HIV Apoptosis Endogenous Metabolite
  3. 5-Fluorouracil

5-Fluorouracil  (Synonyms: 5-FU)

Cat. No.: HY-90006 Purity: 99.99%
SDS COA Handling Instructions

5-fluorouracile (5-FU) est un analogue de l'uracile et un agentpuissant antitumoral. 5-fluorouracile affecte la synthèse de pyrimidine en inhibant la thymidylate synthétase épuisant ainsi les pools de dTTP intracellulaires. 5-fluorouracile induit l'apoptose et peut être utilisé comme sensibilisateur chimique. 5-fluorouracile inhibe également HIV.

5-Fluorouracil (5-FU) ist ein Analogon von Uracil und ein wirksames Antitumormittel. 5-Fluorouracil beeinflusst die pyrimidine synthesis, indem es die Thymidylatsynthetase hemmt und somit die intrazellulären dTTP-Pools verarmt. 5-Fluorouracil induziert apoptosis und kann als chemischer Sensibilisator verwendet werden. 5-Fluorouracil hemmt auch HIV. 5-Fluorouracil (5-FU) could disrupt the exosome specific rRNA processing.

5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer. 5-Fluorouracil also inhibits HIV.

For research use only. We do not sell to patients.

5-Fluorouracil Chemical Structure

5-Fluorouracil Chemical Structure

CAS No. : 51-21-8

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Customer Review

Based on 223 publication(s) in Google Scholar

Other Forms of 5-Fluorouracil:

Top Publications Citing Use of Products

204 Publications Citing Use of MCE 5-Fluorouracil

IF
WB
Proliferation Assay
IHC
RT-PCR

    5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2022 Oct;9(30):e2200717.  [Abstract]

    A transient upregulation and subsequent downregulation of RSK2 phosphorylation at Thr577 by 5-Fluorouracil (5-FU), which is accompanied by the accumulation of γ‐H2AX phosphorylation in a time‐dependent manner.

    5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2022 Oct;9(30):e2200717.  [Abstract]

    In Hct116 cells, the inhibitory effects of 5-Fluorouracil (5-FU on cell growth at 2-10 μM are significantly enhanced by RSK2 or PAK4 inhibitors in short‐term and long‐term assays.

    5-Fluorouracil purchased from MedChemExpress. Usage Cited in: J Immunother Cancer. 2022 Aug;10(8):e004006.  [Abstract]

    Hep3B and Huh7 cells are treated with 5-Fluorouracil for 24 h, then the cellular protein expression of p-IRF3 and pP65 is detected by immunoblotting.

    5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Int J Biol Sci. 2022 Apr 11;18(7):2882-2897.  [Abstract]

    Representative immunoblots assessing apoptosis induced by 5-Fluorouracil (5-FU) in immortalized human ventricular myocytes (AC16).

    5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2021 Nov;8(21):e2101936.  [Abstract]

    ER stress pathways in HCT116/5-FU cells treated with 5-Fluorouracil (5-FU; 60 μM) with SR140333 or Aprepitant either as single agents or in combination at 24 h.

    5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2021 Nov;8(21):e2101936.  [Abstract]

    Cell viability upon treatment with 5-Fluorouracil (5-FU; 60 μM), SR140333, or Aprepitant either as single agents or in combination at 24 h in HCT116 cells.

    5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2021 Nov;8(21):e2101936.  [Abstract]

    Western blotting of drug-resistant proteins in HCT116/5-FU cells treated with 5-Fluorouracil (5-FU; 80 μM) at 48 h.

    5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2021 Nov;8(21):e2101936.  [Abstract]

    The combination of SR140333 or aprepitant and 5-Fluorouracil (5-FU; mg/kg) decreases the expression levels of ABCC1, ABCG2, p-ERK1/2, and c-Myc and increased those of p-PERK, ATF4, and CHOP compared with 5-FU treatment alone.

    5-Fluorouracil purchased from MedChemExpress. Usage Cited in: J Exp Clin Cancer Res. 2021 Apr 30;40(1):150.  [Abstract]

    Inhibition rate of proliferation in pcDNA3.1 or ZBTB28 transfected cells treated with gradient concentration of 5-FU for 72 hours.

    5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Proc Natl Acad Sci U S A. 2021 Jul 20;118(29):e2026813118.  [Abstract]

    Overexpression of RMRP impairs 5-FU–induced p53 activation determined by RT-qPCR.

    5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Proc Natl Acad Sci U S A. 2021 Jul 20;118(29):e2026813118.  [Abstract]

    Overexpression of RMRP impairs 5-FU-induced p53 activation determined by IB.

    5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2021 Apr 1;12(4):338.  [Abstract]

    SW620, CACO2, and HCT15 cells are treated with different concentrations of UTD1 and 5-Fluorouracil (5-FU), and cell viability is measured by CCK-8.

    5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Int J Biochem Cell Biol. 2018 Mar;96:9-19.  [Abstract]

    Hep3B cells are treated with 2 μmol Shikonin, 5-FU, BSNQ or OSNQ for different times (3, 6, 12 and 24 h), and stained with Annexin V and PI. The apoptotic cells are detected by fluorescence microscopy and quantified as percentages.

    5-Fluorouracil purchased from MedChemExpress. Usage Cited in: J Cell Biochem. 2018 Nov 28.  [Abstract]

    The expressions of apoptotic-related proteins, cleaved-PARP, caspase-3-active are detected in control, STAT5A, STAT5A+5-Fu, DEC2+5-Fu, DEC2/STAT5A+5-Fu of MKN45 and MKN28 cell lines using Western blot analysis.

    5-Fluorouracil purchased from MedChemExpress. Usage Cited in: J Cell Biochem. 2018 Nov 28.  [Abstract]

    MKN45 and MKN28 cells transfected with empty and DEC2 vectors are incubated in control medium or 5-Fu of 10 μM for 48 hours, then proliferation ratio of these cells is figured by EdU incorporation assay.

    5-Fluorouracil purchased from MedChemExpress. Usage Cited in: J Cell Biochem. 2018 Nov 28.  [Abstract]

    The expressions of apoptotic-related proteins, cleaved-PARP, caspase-3-active and survivin are detected in MKN45, MKN45+5-Fu, MKN45-EV, MKN45-DEC2, MKN45-DEC2+5-Fu, MKN28, MKN28+5-Fu, MKN28-EV, MKN28-DEC2, MKN28-DEC2+5-Fu cells using Western blot analysis.

    5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Biochem Biophys Res Commun. 2018 Jun 27;501(3):636-642.  [Abstract]

    Immunoblot analysis of the expression levels of BCL-2 and BAX after treatment of HCT116 TP53-/- cells with 20 μM 5-FU and 1.25 μM DHA alone or in combination for 48 h. Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) served as a loading control.

    5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Med Sci Monit. 2018 Sep 21;24:6666-6672.  [Abstract]

    Expression of protein of OPA1, Mfn1, Mfn2, Drp1 and Fis1 in heart mitochondria of rats treated with different 5-FU concentrations. The control group is intraperitonealled injection with same amount of physiological saline.

    5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Tumour Biol. 2016 Jul;37(7):8811-24.  [Abstract]

    Assays for autophagy activity. Immunoblot analysis for LC3B. Compared with the Lenti-NC cells, the Lenti-CD44v6 cells display a higher intensity of autophagy flux but not steady-state levels when treated with 5-FU (*P<0.001).

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    Description

    5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[1][2]. 5-Fluorouracil also inhibits HIV[3].

    IC50 & Target[1][6]

    HIV

     

    Cellular Effect
    Cell Line Type Value Description References
    143B IC50
    13.01 μM
    Compound: FUra
    Cytotoxicity against human 143B cells after 72 hrs by SRB assay
    Cytotoxicity against human 143B cells after 72 hrs by SRB assay
    [PMID: 27073055]
    143B IC50
    16.31 μM
    Compound: FUra
    Cytotoxicity against human thymidine kinase deficient 143B cells after 72 hrs by SRB assay
    Cytotoxicity against human thymidine kinase deficient 143B cells after 72 hrs by SRB assay
    [PMID: 27073055]
    143B IC50
    25.216 μM
    Compound: 5-FU
    Antiproliferative activity against human 143B cells after 48 hrs by MTT assay
    Antiproliferative activity against human 143B cells after 48 hrs by MTT assay
    [PMID: 29223717]
    2008 IC50
    4.2 μM
    Compound: 1, 5-FU
    Growth inhibition of human 2008 cells by crystal violet assay
    Growth inhibition of human 2008 cells by crystal violet assay
    [PMID: 23075414]
    4T1 IC50
    23 μM
    Compound: 5 Fluorouracil
    Cytotoxicity against mouse 4T1 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    Cytotoxicity against mouse 4T1 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    [PMID: 27496212]
    4T1 IC50
    28.12 μM
    Compound: 5-Fu
    Anticancer activity against mouse 4T1 cells expressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay
    Anticancer activity against mouse 4T1 cells expressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 31509699]
    786-0 IC50
    > 10 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human 786-0 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
    Antiproliferative activity against human 786-0 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
    [PMID: 27295506]
    786-0 GI50
    0.72 μM
    Compound: 5-FU
    Anticancer activity against human 786-0 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human 786-0 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    786-0 GI50
    0.72 μM
    Compound: 5-FU
    Growth inhibition of human 786-0 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human 786-0 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    A2780 IC50
    0.2 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human A2780 after 24 hrs by MTT assay
    Cytotoxicity against human A2780 after 24 hrs by MTT assay
    [PMID: 19338315]
    A2780 IC50
    0.65 μg/mL
    Compound: 5-FU, 5-fluorouracil
    Cytotoxicity against human A2780 cells by MTT assay
    Cytotoxicity against human A2780 cells by MTT assay
    [PMID: 18205316]
    A2780 IC50
    14 μM
    Compound: 5-FU
    Antiproliferative activity against human A2780 cells expressing p53 after 72 hrs by celltiter-glo assay
    Antiproliferative activity against human A2780 cells expressing p53 after 72 hrs by celltiter-glo assay
    [PMID: 20873740]
    A2780 GI50
    3.5 μM
    Compound: 5FU
    Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay
    [PMID: 21489802]
    A2780 GI50
    4.4 μM
    Compound: 5-FU
    Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay
    [PMID: 19664930]
    A2780 IC50
    5 μM
    Compound: 5-Fu
    Cytotoxicity against human A2780 cells after 96 hrs by MTT assay
    Cytotoxicity against human A2780 cells after 96 hrs by MTT assay
    [PMID: 16499317]
    A2780 IC50
    5.1 μM
    Compound: 1, 5-FU
    Growth inhibition of human A2780 cells by crystal violet assay
    Growth inhibition of human A2780 cells by crystal violet assay
    [PMID: 23075414]
    A2780 IC50
    5.4 μM
    Compound: 5-Fu
    Cytotoxicity against human A2780 cells by MTT method
    Cytotoxicity against human A2780 cells by MTT method
    [PMID: 23164710]
    A2780 IC50
    7.21 μM
    Compound: 5-FU
    Antiproliferative activity against human A2780 cells expressing p53 gene after 72 hrs by proliferative assay
    Antiproliferative activity against human A2780 cells expressing p53 gene after 72 hrs by proliferative assay
    [PMID: 18469809]
    A-375 IC50
    21.09 μM
    Compound: 5-Fu
    Anticancer activity against human A375 cells expressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay
    Anticancer activity against human A375 cells expressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 31509699]
    A-375 IC50
    3.52 μM
    Compound: 5-FU
    Cytotoxicity against human A-375 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    Cytotoxicity against human A-375 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    [PMID: 36331508]
    A-375 IC50
    46.55 μM
    Compound: 5-FU
    Cytotoxicity against human A375 cells after 48 hrs by MTT assay
    Cytotoxicity against human A375 cells after 48 hrs by MTT assay
    [PMID: 22483608]
    A-375 IC50
    5.98 μM
    Compound: 5-Fu
    Antiproliferative activity against human A-375 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay
    Antiproliferative activity against human A-375 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay
    [PMID: 35797896]
    A-431 IC50
    0.018 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human A431 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A431 cells after 48 hrs by MTT assay
    [PMID: 19423198]
    A-431 IC50
    2.17 μg/mL
    Compound: 5-Fluorouracil
    Cytotoxicity against human A431 cells after 48 hrs by MTT assay
    Cytotoxicity against human A431 cells after 48 hrs by MTT assay
    [PMID: 20800480]
    A-431 ED50
    44 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human A431 cells by MTT assay
    Cytotoxicity against human A431 cells by MTT assay
    [PMID: 12027771]
    A498 GI50
    0.35 μM
    Compound: 5-FU
    Anticancer activity against human A498 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human A498 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    A498 GI50
    0.35 μM
    Compound: 5-FU
    Growth inhibition of human A498 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human A498 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    A498 IC50
    8.83 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human A498 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
    Antiproliferative activity against human A498 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
    [PMID: 27295506]
    A549 IC50
    > 10 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay
    [PMID: 32659087]
    A549 IC50
    > 100 μM
    Compound: 5-Fu
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    [PMID: 31057737]
    A549 IC50
    > 100 μM
    Compound: 5-FU
    Antitumor activity against Homo sapiens (human) A549 cells assessed as inhibition of cell viability after 72 hr by MTT assay
    Antitumor activity against Homo sapiens (human) A549 cells assessed as inhibition of cell viability after 72 hr by MTT assay
    10.1007/s00044-012-0283-8
    A549 IC50
    > 20 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
    [PMID: 21381696]
    A549 IC50
    > 30 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    [PMID: 33248852]
    A549 IC50
    > 50 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 33538581]
    A549 IC50
    > 50 μM
    Compound: 5-Fu
    Antiproliferative activity against human A549 cells assessed as cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as cell viability after 72 hrs by MTT assay
    [PMID: 26922223]
    A549 IC50
    0.01 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human A549 cells after 48 hrs by SRB assay
    Cytotoxicity against human A549 cells after 48 hrs by SRB assay
    [PMID: 25259515]
    A549 IC50
    0.18 μg/mL
    Compound: 5-FU, 5-fluorouracil
    Cytotoxicity against human A549 cells by MTT assay
    Cytotoxicity against human A549 cells by MTT assay
    [PMID: 18205316]
    A549 GI50
    0.18 μM
    Compound: 5-FU
    Anticancer activity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    A549 GI50
    0.18 μM
    Compound: 5-FU
    Growth inhibition of human A549/ATCC cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human A549/ATCC cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    A549 IC50
    0.2 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human A549 after 24 hrs by MTT assay
    Cytotoxicity against human A549 after 24 hrs by MTT assay
    [PMID: 19338315]
    A549 ED50
    0.4 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human A549 cells by MTT assay
    Cytotoxicity against human A549 cells by MTT assay
    [PMID: 16309328]
    A549 IC50
    0.42 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells after 3 days by MTT assay
    Cytotoxicity against human A549 cells after 3 days by MTT assay
    [PMID: 22000925]
    A549 IC50
    0.43 μM
    Compound: 5-Fu
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    [PMID: 29254641]
    A549 IC50
    0.5 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human A549 cells assessed as inhibition of cell growth after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human A549 cells assessed as inhibition of cell growth after 48 hrs by sulforhodamine B assay
    10.1039/C5MD00289C
    A549 IC50
    0.69 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
    [PMID: 32485532]
    A549 IC50
    0.98 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as growth inhibition measured at 48 hrs by SRB assay
    Cytotoxicity against human A549 cells assessed as growth inhibition measured at 48 hrs by SRB assay
    [PMID: 24727462]
    A549 IC50
    1.1 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human A549 cells after 24 hrs by MTT assay
    Cytotoxicity against human A549 cells after 24 hrs by MTT assay
    [PMID: 24060486]
    A549 IC50
    1.1 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human A549 cells assessed as cell growth inhibition by MTT assay
    Cytotoxicity against human A549 cells assessed as cell growth inhibition by MTT assay
    [PMID: 26629861]
    A549 IC50
    1.16 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    [PMID: 27987485]
    A549 IC50
    1.2 μM
    Compound: 5-F
    Cytotoxicity against human A549 cells after 24 hrs by MTT assay
    Cytotoxicity against human A549 cells after 24 hrs by MTT assay
    [PMID: 28254697]
    A549 IC50
    1.3 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells after 24 hrs by MTT assay
    Cytotoxicity against human A549 cells after 24 hrs by MTT assay
    [PMID: 24835633]
    A549 IC50
    1.4 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    [PMID: 26854375]
    A549 IC50
    1.4 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells after 96 hrs by MTT assay
    Cytotoxicity against human A549 cells after 96 hrs by MTT assay
    [PMID: 16499317]
    A549 IC50
    1.54 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells by MTT method
    Cytotoxicity against human A549 cells by MTT method
    [PMID: 23164710]
    A549 IC50
    1.6 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    [PMID: 28431881]
    A549 IC50
    1.65 μM
    Compound: 5-Fu
    Antiproliferative activity against human A549 cells assessed as reduction in cell growth by CCK8 assay
    Antiproliferative activity against human A549 cells assessed as reduction in cell growth by CCK8 assay
    [PMID: 33964443]
    A549 IC50
    1.65 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as growth inhibition after 24 to 48 hrs by sulforhodamine B assay
    Cytotoxicity against human A549 cells assessed as growth inhibition after 24 to 48 hrs by sulforhodamine B assay
    [PMID: 24996138]
    A549 IC50
    1.7 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    [PMID: 27528432]
    A549 IC50
    1.9 μM
    Compound: 5-Fluoro uracilc
    Cytotoxicity against human A549 cells assessed as growth inhibition after 24 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as growth inhibition after 24 hrs by MTT assay
    [PMID: 24641975]
    A549 IC50
    10.32 μM
    Compound: 5-FU
    Antiproliferative activity in human A549 cells after 72 hrs by MTT assay
    Antiproliferative activity in human A549 cells after 72 hrs by MTT assay
    10.1039/C6MD00252H
    A549 IC50
    10.5 μg/mL
    Compound: 5-Fu
    Cytotoxicity against human A549 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    [PMID: 27262600]
    A549 IC50
    10.5 μM
    Compound: 5-Fu
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    [PMID: 28073676]
    A549 IC50
    10.55 μM
    Compound: 5-FU
    Cytotoxicity against human A549 assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human A549 assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 30709651]
    A549 IC50
    10.65 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells incubated for 48 to 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells incubated for 48 to 72 hrs by MTT assay
    [PMID: 28395218]
    A549 GI50
    10.7 μM
    Compound: 5-Fu
    Antiproliferative activity against human A549 cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells incubated for 48 hrs by MTT assay
    [PMID: 32832031]
    A549 IC50
    10.85 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells by MTT assay
    Cytotoxicity against human A549 cells by MTT assay
    [PMID: 18644718]
    A549 EC50
    100 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    [PMID: 20409617]
    A549 IC50
    100.02 μM
    Compound: 5-FU
    Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 35085721]
    A549 IC50
    104.5 μM
    Compound: 5-FU
    Cytotoxicity in human A549 cells assessed as growth inhibition incubated for 24 hrs by MTT assay
    Cytotoxicity in human A549 cells assessed as growth inhibition incubated for 24 hrs by MTT assay
    [PMID: 31128448]
    A549 IC50
    108.7 μM
    Compound: 5-FU
    Anticancer activity against human A549 cells assessed as inhibition of cell proliferation by MTT assay
    Anticancer activity against human A549 cells assessed as inhibition of cell proliferation by MTT assay
    [PMID: 36439975]
    A549 IC50
    11.2 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay
    [PMID: 29133037]
    A549 IC50
    11.3 μM
    Compound: 5-fluorouracil
    Cytotoxicity in human A549 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity in human A549 cells assessed as cell viability after 48 hrs by MTT assay
    [PMID: 21250700]
    A549 IC50
    11.4 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 29133037]
    A549 IC50
    11.42 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
    [PMID: 35635947]
    A549 IC50
    12.8 μM
    Compound: 5-Fu
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    [PMID: 22840493]
    A549 IC50
    12.92 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    [PMID: 28863355]
    A549 IC50
    13.18 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    [PMID: 30388465]
    A549 IC50
    13.18 μM
    Compound: 5-Fu
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    [PMID: 29635165]
    A549 IC50
    13.95 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as growth inhibition by MTT assay
    Cytotoxicity against human A549 cells assessed as growth inhibition by MTT assay
    [PMID: 27769034]
    A549 IC50
    14.15 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    [PMID: 26227777]
    A549 IC50
    14.53 μM
    Compound: 5-Fu
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition incubated for 4 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition incubated for 4 hrs by MTT assay
    [PMID: 32992255]
    A549 IC50
    14.96 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTS assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTS assay
    [PMID: 30472605]
    A549 IC50
    15.1 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    [PMID: 28400238]
    A549 IC50
    15.14 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    [PMID: 34624825]
    A549 IC50
    15.3 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    [PMID: 33740546]
    A549 IC50
    15.93 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human A549 cells in presence of ubenimex after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells in presence of ubenimex after 48 hrs by MTT assay
    [PMID: 29202398]
    A549 IC50
    16.1 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 28117202]
    A549 IC50
    16.63 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human A549 cells assessed as cell growth inhibition by MTT assay
    Cytotoxicity against human A549 cells assessed as cell growth inhibition by MTT assay
    [PMID: 27913179]
    A549 IC50
    16.96 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    [PMID: 27322756]
    A549 IC50
    17.02 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    [PMID: 29202398]
    A549 IC50
    17.3 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    [PMID: 32987314]
    A549 IC50
    19.52 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    [PMID: 29486954]
    A549 GI50
    19.76 μM
    Compound: 4; 5-FU
    Antiproliferative activity against human A549 cells measured after 48 hrs by SRB assay
    Antiproliferative activity against human A549 cells measured after 48 hrs by SRB assay
    [PMID: 32683166]
    A549 IC50
    2 μg/mL
    Compound: 5-Fluorouracil
    Cytotoxicity against human A549 cells by SRB assay
    Cytotoxicity against human A549 cells by SRB assay
    [PMID: 19700322]
    A549 IC50
    2.05 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 30921757]
    A549 IC50
    2.05 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    [PMID: 30243153]
    A549 GI50
    2.09 μM
    Compound: 5-FU
    Growth inhibition of human A549 cells after 48 hrs by SRB assay
    Growth inhibition of human A549 cells after 48 hrs by SRB assay
    [PMID: 28400235]
    A549 IC50
    2.13 μM
    Compound: 5-Fluorouracil
    Anticancer activity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay
    Anticancer activity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay
    [PMID: 26231080]
    A549 IC50
    2.33 μM
    Compound: 5-Fu
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 31202992]
    A549 IC50
    2.36 μM
    Compound: 5-Fluorouracil
    Cytotoxicity activity against human A549 cells incubated for 48 hrs by SRB assay
    Cytotoxicity activity against human A549 cells incubated for 48 hrs by SRB assay
    [PMID: 34119830]
    A549 IC50
    2.4 μM
    Compound: 5-fluorouracil
    Anticancer activity against human A549 cells assessed as cell viability after 48 hrs by SRB assay
    Anticancer activity against human A549 cells assessed as cell viability after 48 hrs by SRB assay
    [PMID: 21074444]
    A549 GI50
    2.4 μM
    Compound: 5FU
    Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay
    [PMID: 21489802]
    A549 IC50
    2.42 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 31546197]
    A549 IC50
    2.53 μM
    Compound: 5-Fu
    Antiproliferation activity against human A549 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    Antiproliferation activity against human A549 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    [PMID: 34186178]
    A549 IC50
    2.65 μM
    Compound: 5-FU
    Antitumor activity against human A549 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay
    Antitumor activity against human A549 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay
    [PMID: 36324491]
    A549 IC50
    2.8 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    [PMID: 29133046]
    A549 IC50
    2.8 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    [PMID: 27875779]
    A549 IC50
    2.8 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human A549 cells after 72 hrs by WST8 assay
    Antiproliferative activity against human A549 cells after 72 hrs by WST8 assay
    [PMID: 25919052]
    A549 IC50
    2.8 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by WST-8 assay
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by WST-8 assay
    [PMID: 27311895]
    A549 IC50
    2.9 mM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    [PMID: 27847140]
    A549 IC50
    20.13 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    [PMID: 24211021]
    A549 IC50
    20.8 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human A549 cells by SRB method
    Cytotoxicity against human A549 cells by SRB method
    [PMID: 19422203]
    A549 IC50
    21.58 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    [PMID: 27133593]
    A549 IC50
    22.28 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    [PMID: 26363869]
    A549 IC50
    22.5 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    [PMID: 32987314]
    A549 IC50
    22.62 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    10.1039/C6MD00061D
    A549 IC50
    23.5 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    [PMID: 30108895]
    A549 IC50
    23.57 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    [PMID: 30568759]
    A549 IC50
    24.66 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay
    [PMID: 27400887]
    A549 IC50
    24.87 μg/mL
    Compound: 5-F
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    [PMID: 24342667]
    A549 IC50
    25.3 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
    [PMID: 32987314]
    A549 IC50
    26 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    10.1039/C6MD00234J
    A549 IC50
    27.08 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay
    [PMID: 37122546]
    A549 IC50
    28.64 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    [PMID: 30677614]
    A549 IC50
    29.17 μM
    Compound: 5-Fu
    Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation by MTT assay
    Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation by MTT assay
    [PMID: 36336316]
    A549 IC50
    3.1 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human A549 cells after 4 days by MTT assay
    Cytotoxicity against human A549 cells after 4 days by MTT assay
    [PMID: 24359303]
    A549 IC50
    3.1 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells by MTT assay
    Cytotoxicity against human A549 cells by MTT assay
    [PMID: 18606546]
    A549 IC50
    3.1 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells by MTT microassay
    Cytotoxicity against human A549 cells by MTT microassay
    [PMID: 17320246]
    A549 IC50
    3.2 x 10-1 μg/mL
    Compound: fluorouracil
    Cytotoxicity against human A549 cells by MTT assay
    Cytotoxicity against human A549 cells by MTT assay
    [PMID: 22011319]
    A549 IC50
    3.47 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay
    [PMID: 26735909]
    A549 IC50
    3.52 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells after 72 hrs by MTS assay
    Antiproliferative activity against human A549 cells after 72 hrs by MTS assay
    [PMID: 27575478]
    A549 IC50
    3.52 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells after 72 hrs by MTS assay
    Antiproliferative activity against human A549 cells after 72 hrs by MTS assay
    [PMID: 26703795]
    A549 IC50
    3.52 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells by MTS assay
    Cytotoxicity against human A549 cells by MTS assay
    [PMID: 29843103]
    A549 IC50
    3.52 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    [PMID: 23665106]
    A549 GI50
    3.6 μM
    Compound: fluorouracil
    Cytotoxicity against human A549 cells after 72 hrs by SRB assay
    Cytotoxicity against human A549 cells after 72 hrs by SRB assay
    [PMID: 23964677]
    A549 EC50
    3.61 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    [PMID: 12027739]
    A549 IC50
    3.85 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay
    [PMID: 35290844]
    A549 IC50
    3.98 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    [PMID: 27092413]
    A549 IC50
    30.47 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 27614408]
    A549 IC50
    31.33 μM
    Compound: 5-FU
    Cytotoxic activity against human A549 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
    Cytotoxic activity against human A549 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
    [PMID: 26706349]
    A549 IC50
    31.52 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells by MTT assay
    Cytotoxicity against human A549 cells by MTT assay
    [PMID: 22801644]
    A549 IC50
    32.15 μM
    Compound: 5-Fu
    Cytotoxic activity against human A549 cells assessed as reduction in cell viability after 72 hrs by SRB assay
    Cytotoxic activity against human A549 cells assessed as reduction in cell viability after 72 hrs by SRB assay
    [PMID: 28011223]
    A549 IC50
    32.4 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human A549 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay
    Cytotoxicity against human A549 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay
    [PMID: 36970146]
    A549 IC50
    33.68 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition by MTT assay
    Antiproliferative activity against human A549 cells assessed as cell growth inhibition by MTT assay
    [PMID: 31945642]
    A549 IC50
    34.27 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    [PMID: 26883148]
    A549 IC50
    34.27 μM
    Compound: 5FU
    Cytotoxicity against human A549 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay
    Cytotoxicity against human A549 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay
    [PMID: 28038327]
    A549 IC50
    34.33 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells after 3 days by MTT assay
    Cytotoxicity against human A549 cells after 3 days by MTT assay
    [PMID: 24095745]
    A549 IC50
    34.33 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    [PMID: 23988357]
    A549 IC50
    34.34 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    [PMID: 24953029]
    A549 IC50
    34.47 μM
    Compound: 5-FU
    Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 28754470]
    A549 IC50
    34.47 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells by MTT assay
    Antiproliferative activity against human A549 cells by MTT assay
    [PMID: 33109400]
    A549 IC50
    35.05 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    [PMID: 22483608]
    A549 IC50
    35.41 μM
    Compound: Fluorouracil
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    [PMID: 27128180]
    A549 IC50
    35.41 μM
    Compound: Fluorouracil
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    [PMID: 25016234]
    A549 IC50
    35.41 μM
    Compound: Fluorouracil
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    [PMID: 22809558]
    A549 IC50
    36.34 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay
    [PMID: 25841199]
    A549 IC50
    36.8 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells assessed as decrease in cell viability by MTT assay
    Cytotoxicity against human A549 cells assessed as decrease in cell viability by MTT assay
    [PMID: 29489361]
    A549 IC50
    38.2 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells by MTT assay
    Cytotoxicity against human A549 cells by MTT assay
    [PMID: 28371676]
    A549 IC50
    38.23 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells after 2 days by MTT assay
    Cytotoxicity against human A549 cells after 2 days by MTT assay
    [PMID: 25841196]
    A549 IC50
    38.7 μM
    Compound: 5-Fu
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    [PMID: 30737134]
    A549 IC50
    39.86 μM
    Compound: 5-FU
    Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 29657100]
    A549 IC50
    39.86 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 27448774]
    A549 IC50
    4.1 μg/mL
    Compound: 5-Fu
    Anticancer activity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
    Anticancer activity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
    [PMID: 25017036]
    A549 GI50
    4.2 μM
    Compound: 5-Fluorouracil
    Growth inhibition of human A549 cells after 48 hrs by SRB assay
    Growth inhibition of human A549 cells after 48 hrs by SRB assay
    [PMID: 28898082]
    A549 IC50
    4.21 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed cell viability after 48 hrs by SRB assay
    Cytotoxicity against human A549 cells assessed cell viability after 48 hrs by SRB assay
    [PMID: 23044370]
    A549 IC50
    4.21 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human A549 cells after 48 hrs by sulforhodamine B assay
    [PMID: 24956552]
    A549 IC50
    4.3 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    [PMID: 30318440]
    A549 IC50
    4.3 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human A549 cells by MTT assay
    Antiproliferative activity against human A549 cells by MTT assay
    [PMID: 31546197]
    A549 IC50
    4.52 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    [PMID: 36331508]
    A549 GI50
    4.55 μM
    Compound: 5-fluorouracil
    Growth inhibition of human A549 cells after 48 hrs by SRB assay
    Growth inhibition of human A549 cells after 48 hrs by SRB assay
    [PMID: 24797798]
    A549 IC50
    4.7 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as decrease in cell viability after 72 hrs by WST8 assay
    Cytotoxicity against human A549 cells assessed as decrease in cell viability after 72 hrs by WST8 assay
    [PMID: 28558970]
    A549 IC50
    4.9 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human A549 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23501113]
    A549 IC50
    4.9 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay
    Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay
    [PMID: 26222449]
    A549 IC50
    40.38 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
    Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
    [PMID: 25959813]
    A549 IC50
    44.05 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells assessed as induction of cell death incubated for 2 days by MTT assay
    Cytotoxicity against human A549 cells assessed as induction of cell death incubated for 2 days by MTT assay
    [PMID: 26259802]
    A549 IC50
    44.05 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells after 2 days by MTT assay
    Cytotoxicity against human A549 cells after 2 days by MTT assay
    [PMID: 24767839]
    A549 IC50
    44.05 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
    [PMID: 27189676]
    A549 IC50
    44.05 μM
    Compound: 5-Fu
    Growth inhibition against human A549 cells after 48 hrs by MTT assay
    Growth inhibition against human A549 cells after 48 hrs by MTT assay
    [PMID: 23999046]
    A549 IC50
    44.05 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    [PMID: 23558238]
    A549 IC50
    5.4 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells after 24 hrs by trypan blue exclusion assay
    Antiproliferative activity against human A549 cells after 24 hrs by trypan blue exclusion assay
    [PMID: 20403701]
    A549 IC50
    5.6 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells by MTT assay
    Cytotoxicity against human A549 cells by MTT assay
    [PMID: 21515044]
    A549 IC50
    5.62 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    [PMID: 23920246]
    A549 IC50
    5.64 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells after 24 hrs by MTT assay
    Cytotoxicity against human A549 cells after 24 hrs by MTT assay
    [PMID: 22182926]
    A549 IC50
    5.64 μM
    Compound: 5-Fu
    Growth inhibition of human A549 cells after 48 hrs by MTT assay
    Growth inhibition of human A549 cells after 48 hrs by MTT assay
    [PMID: 23353737]
    A549 IC50
    5.64 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells by after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells by after 48 hrs by MTT assay
    [PMID: 22579780]
    A549 IC50
    5.91 μM
    Compound: 5-Fluoro uracil
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    [PMID: 19689125]
    A549 IC50
    50.43 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 31673307]
    A549 IC50
    50.5 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells after 72 hrs by SRB method
    Cytotoxicity against human A549 cells after 72 hrs by SRB method
    [PMID: 19324555]
    A549 IC50
    50.5 μM
    Compound: 5-FU
    In vitro inhibitory concentration required against human lung carcinoma A-549 cell line was determined after 72 hrs of drug exposure using SRB method
    In vitro inhibitory concentration required against human lung carcinoma A-549 cell line was determined after 72 hrs of drug exposure using SRB method
    [PMID: 15380199]
    A549 IC50
    51.64 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    [PMID: 25164762]
    A549 IC50
    54.8 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    [PMID: 22244588]
    A549 IC50
    54.82 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay
    [PMID: 26873416]
    A549 IC50
    55.7 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    [PMID: 29305189]
    A549 IC50
    55.73 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    [PMID: 30007564]
    A549 IC50
    56 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    [PMID: 23356786]
    A549 IC50
    6.6 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 34883453]
    A549 IC50
    6.69 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as growth inhibition rate after 96 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as growth inhibition rate after 96 hrs by MTT assay
    [PMID: 25203783]
    A549 IC50
    6.76 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    [PMID: 26595184]
    A549 IC50
    6.8 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells measured after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells measured after 72 hrs by MTT assay
    [PMID: 27537924]
    A549 IC50
    6.8 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured for 24 hrs
    Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured for 24 hrs
    [PMID: 31945642]
    A549 IC50
    66 μg/mL
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    [PMID: 29207336]
    A549 IC50
    69.07 μM
    Compound: 5-Fu
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    [PMID: 29958763]
    A549 IC50
    7.1 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells assessed as reduction in viability after 48 hrs by SRB assay
    Cytotoxicity against human A549 cells assessed as reduction in viability after 48 hrs by SRB assay
    [PMID: 31103402]
    A549 IC50
    7.1 μM
    Compound: 5-Fu
    Antiproliferative activity against human A549 cells after 3 days by sulforhodamine B assay
    Antiproliferative activity against human A549 cells after 3 days by sulforhodamine B assay
    [PMID: 30248657]
    A549 IC50
    7.244 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    [PMID: 26301558]
    A549 IC50
    7.51 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    [PMID: 25870131]
    A549 IC50
    7.62 μM
    Compound: 5-Fu
    Antiproliferative activity against human A549 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
    [PMID: 25113877]
    A549 IC50
    71.09 μM
    Compound: 5-Fu
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    [PMID: 30142612]
    A549 IC50
    78 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells after 48 hrs by XTT method
    Cytotoxicity against human A549 cells after 48 hrs by XTT method
    [PMID: 20151671]
    A549 IC50
    8.12 μM
    Compound: 5-Fu
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
    [PMID: 35609396]
    A549 IC50
    8.13 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells after 48 hrs by CCK-8 assay
    Antiproliferative activity against human A549 cells after 48 hrs by CCK-8 assay
    [PMID: 27542307]
    A549 IC50
    8.13 μM
    Compound: 5-Fu
    Antiproliferative activity against human A549 cells after 48 hrs by CCK8 assay
    Antiproliferative activity against human A549 cells after 48 hrs by CCK8 assay
    [PMID: 26786698]
    A549 IC50
    8.13 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation by CCK8 assay
    Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation by CCK8 assay
    [PMID: 25442303]
    A549 IC50
    8.48 μM
    Compound: 5-FU
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    Antiproliferative activity against human A549 cells after 48 hrs by MTT assay
    [PMID: 29133051]
    A549 IC50
    8.5 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay
    [PMID: 31829592]
    A549 IC50
    8.71 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    [PMID: 23685571]
    A549 IC50
    8.83 μM
    Compound: 5-Fu
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    [PMID: 22687745]
    A549 IC50
    8.9 μM
    Compound: 5-Fu
    Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    [PMID: 28987604]
    A549 IC50
    8.92 μM
    Compound: 5-Fu
    Antiproliferative activity against human A549 cells by MTT assay
    Antiproliferative activity against human A549 cells by MTT assay
    [PMID: 24095094]
    A549 IC50
    88.9 μM
    Compound: 5-FU
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    Cytotoxicity against human A549 cells after 48 hrs by MTT assay
    [PMID: 23067549]
    A549 IC50
    9 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human A549 cells after 72 hrs by WST-8 assay
    Antiproliferative activity against human A549 cells after 72 hrs by WST-8 assay
    [PMID: 26606140]
    A549 IC50
    9.19 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    Cytotoxicity against human A549 cells after 72 hrs by MTT assay
    [PMID: 18440233]
    A549 IC50
    9.2 μM
    Compound: 5-FU
    Cytotoxicity against A549 cells after 48 hrs by MTT assay
    Cytotoxicity against A549 cells after 48 hrs by MTT assay
    [PMID: 17604394]
    A549/TR IC50
    112.23 μM
    Compound: 5-FU
    Cytotoxicity against human A549/TAX cells after 72 hrs by MTT assay
    Cytotoxicity against human A549/TAX cells after 72 hrs by MTT assay
    [PMID: 30677614]
    A549/TR IC50
    84.28 μM
    Compound: 5-FU
    Cytotoxicity against human A549/T cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human A549/T cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 31673307]
    ACHN GI50
    0.27 μM
    Compound: 5-FU
    Anticancer activity against human ACHN cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human ACHN cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    ACHN GI50
    0.29 μM
    Compound: 5-FU
    Growth inhibition of human ACHN cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human ACHN cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    ACHN IC50
    2.73 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human ACHN cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
    Antiproliferative activity against human ACHN cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
    [PMID: 27295506]
    ACHN IC50
    9.874 μg/mL
    Compound: 5-FU
    Cytotoxicity against human ACHN cells after 24 hrs by MTT assay
    Cytotoxicity against human ACHN cells after 24 hrs by MTT assay
    [PMID: 23548704]
    AGS IC50
    > 100 μM
    Compound: 5-FU
    Cytotoxicity against human AGS cells after 72 hrs by SRB method
    Cytotoxicity against human AGS cells after 72 hrs by SRB method
    [PMID: 19324555]
    AGS IC50
    11.04 μM
    Compound: 5-FU
    Antiproliferative activity against human AGS cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Antiproliferative activity against human AGS cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    [PMID: 33248852]
    AGS IC50
    23.24 μM
    Compound: 5-Fu
    Cytotoxicity against human AGS cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity against human AGS cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    [PMID: 34628244]
    AGS GI50
    24.6 μM
    Compound: 5-FU
    Antiproliferative activity against human AGS cells after 48 hrs by MTT assay
    Antiproliferative activity against human AGS cells after 48 hrs by MTT assay
    [PMID: 29040954]
    AGS GI50
    25 μM
    Compound: 5-Fu
    Antiproliferative activity against human AGS cells after 48 hrs by MTT assay
    Antiproliferative activity against human AGS cells after 48 hrs by MTT assay
    [PMID: 28763647]
    AGS IC50
    29.6 μM
    Compound: 5-FU
    Anti-proliferative activity against human AGS cells after 48 hrs by MTT assay
    Anti-proliferative activity against human AGS cells after 48 hrs by MTT assay
    [PMID: 28947149]
    AGS IC50
    370 μM
    Compound: 5-FU
    Cytotoxicity against AGS cells after 48 hrs by MTT assay
    Cytotoxicity against AGS cells after 48 hrs by MTT assay
    [PMID: 17604394]
    AGS IC50
    58 μM
    Compound: 5-Fu
    Cytotoxicity against human AGS cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    Cytotoxicity against human AGS cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    [PMID: 35191714]
    AGS EC50
    7.25 μM
    Compound: 5FU
    Cytotoxicity against human AGS cells assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay
    Cytotoxicity against human AGS cells assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay
    [PMID: 35939803]
    ASPC1 IC50
    2.97 μM
    Compound: 5-FU
    Cytotoxicity against human Aspc-1 cells by crystal violet staining
    Cytotoxicity against human Aspc-1 cells by crystal violet staining
    [PMID: 20930123]
    ASPC1 IC50
    98 μM
    Compound: 5-FU
    Cytotoxicity against human AsPC1 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human AsPC1 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 27448774]
    AZ-521 cell line IC50
    > 100 μM
    Compound: 5-fluorouracil
    Cytotoxicity in human AZ-521 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity in human AZ-521 cells assessed as cell viability after 48 hrs by MTT assay
    [PMID: 21250700]
    AZ-521 cell line IC50
    > 20 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human AZ-521 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity against human AZ-521 cells assessed as cell viability after 48 hrs by MTT assay
    [PMID: 21381696]
    B16 IC50
    1.19 μM
    Compound: 5-Fu
    Cytotoxicity in mouse B16 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Cytotoxicity in mouse B16 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    [PMID: 28987604]
    B16 IC50
    10.52 μM
    Compound: 5-FU
    Antiproliferative activity against mouse B16 cells after 72 hrs by MTT assay
    Antiproliferative activity against mouse B16 cells after 72 hrs by MTT assay
    [PMID: 25529742]
    B16 IC50
    12.62 μM
    Compound: 5-Fu
    Antiproliferative activity against mouse B16 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against mouse B16 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 31877536]
    B16 IC50
    17.85 μM
    Compound: 5-FU
    Antiproliferative activity against mouse B16 cells after 48 hrs by MTT assay
    Antiproliferative activity against mouse B16 cells after 48 hrs by MTT assay
    [PMID: 25164762]
    B16 IC50
    33 μM
    Compound: 5-fu
    Cytotoxicity against mouse B16 cells after 48 hrs by MTT assay
    Cytotoxicity against mouse B16 cells after 48 hrs by MTT assay
    [PMID: 22304344]
    B16 IC50
    4.2 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against mouse B16 cells after 48 hrs by MTT assay
    Cytotoxicity against mouse B16 cells after 48 hrs by MTT assay
    [PMID: 24332497]
    B16 IC50
    7.64 μM
    Compound: 5-fluorouracil
    Cytotoxicity against mouse B16 cells assessed as cell survival after 48 hrs by MTT assay
    Cytotoxicity against mouse B16 cells assessed as cell survival after 48 hrs by MTT assay
    [PMID: 25506718]
    B16 IC50
    8.73 μM
    Compound: 5-FU
    Cytotoxicity against mouse B16 cells by MTT assay
    Cytotoxicity against mouse B16 cells by MTT assay
    [PMID: 18644718]
    B16-BL6 IC50
    0.6 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against mouse B16-BL6 cells assessed as cell viability after 72 hrs by MTT assay
    Antiproliferative activity against mouse B16-BL6 cells assessed as cell viability after 72 hrs by MTT assay
    [PMID: 11575942]
    B16-BL6 EC50
    1.23 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against mouse B16-BL6 cells after 72 hrs by MTT assay
    Antiproliferative activity against mouse B16-BL6 cells after 72 hrs by MTT assay
    [PMID: 12027739]
    B16-BL6 IC50
    5.78 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay
    Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay
    [PMID: 18440233]
    B16-BL6 IC50
    7.39 μM
    Compound: 5-Fluoro uracil
    Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay
    Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay
    [PMID: 19689125]
    B16-F10 IC50
    0.87 μM
    Compound: 5-Fu
    Cytotoxicity against mouse B16F10 cells assessed as inhibition of proliferation after 72 hrs by MTT assay
    Cytotoxicity against mouse B16F10 cells assessed as inhibition of proliferation after 72 hrs by MTT assay
    [PMID: 25180925]
    B16-F10 IC50
    1.43 μM
    Compound: 5-Fu
    Anticancer activity against mouse B16F10 cells assessed as inhibition of proliferation after 72 hrs by MTT assay
    Anticancer activity against mouse B16F10 cells assessed as inhibition of proliferation after 72 hrs by MTT assay
    [PMID: 25655718]
    B16-F10 IC50
    21.41 μM
    Compound: 5-Fluorouracil
    Anticancer activity against mouse B16F10 cells assessed as cell survival measured after 48 hrs by MTT assay
    Anticancer activity against mouse B16F10 cells assessed as cell survival measured after 48 hrs by MTT assay
    [PMID: 23312949]
    B16-F10 IC50
    4 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against mouse B16-F10 cells by MTT assay
    Cytotoxicity against mouse B16-F10 cells by MTT assay
    [PMID: 29280630]
    B16-F10 IC50
    6.29 μM
    Compound: 5-Fu
    Antiproliferative activity against mouse B16/F10 cells after 72 hrs by MTT assay
    Antiproliferative activity against mouse B16/F10 cells after 72 hrs by MTT assay
    [PMID: 29254641]
    BALB/3T3 IC50
    3.23 μM
    Compound: FUra
    Antiproliferative activity against mouse BALB/3T3 cells assessed as growth inhibition after 72 hrs by SRB method
    Antiproliferative activity against mouse BALB/3T3 cells assessed as growth inhibition after 72 hrs by SRB method
    [PMID: 25644674]
    Bcap37 IC50
    15.47 μM
    Compound: 5-Fu
    Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay
    Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay
    [PMID: 27133593]
    Bcap37 IC50
    37.09 μM
    Compound: 5-Fu
    Cytotoxicity against human Bcap37 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay
    Cytotoxicity against human Bcap37 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay
    [PMID: 27400887]
    Bcap37 IC50
    47.09 μM
    Compound: 5-Fu
    Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay
    Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay
    [PMID: 26883148]
    Bcap37 IC50
    47.1 μM
    Compound: 5FU
    Cytotoxicity against human Bcap37 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay
    Cytotoxicity against human Bcap37 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay
    [PMID: 28038327]
    Bcap37 IC50
    5.18 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human Bcap37 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human Bcap37 cells assessed as growth inhibition after 48 hrs by MTT assay
    [PMID: 27189676]
    Bcap37 IC50
    5.18 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay
    Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay
    [PMID: 25554922]
    Bcap37 IC50
    5.33 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay
    Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay
    [PMID: 22405648]
    Bcap37 IC50
    5.58 μM
    Compound: 5-Fu
    Cytotoxicity against human Bcap37 cells assessed as induction of cell death incubated for 2 days by MTT assay
    Cytotoxicity against human Bcap37 cells assessed as induction of cell death incubated for 2 days by MTT assay
    [PMID: 26259802]
    Bcap37 IC50
    5.58 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay
    Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay
    [PMID: 24119869]
    Bel-7402 IC50
    > 500 μM
    Compound: 5-FU
    Cytotoxicity against human Bel7402 cells assessed as growth inhibition by MTT assay
    Cytotoxicity against human Bel7402 cells assessed as growth inhibition by MTT assay
    [PMID: 24684840]
    Bel-7402 IC50
    > 700 μM
    Compound: 5-FU
    Cytotoxicity against 5-fluorouracil-resistant human Bel7402 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against 5-fluorouracil-resistant human Bel7402 cells assessed as growth inhibition after 72 hrs by MTT assay
    [PMID: 26320625]
    Bel-7402 IC50
    0.54 μg/mL
    Compound: 5-FU, 5-fluorouracil
    Cytotoxicity against human Bel 7402 cells by MTT assay
    Cytotoxicity against human Bel 7402 cells by MTT assay
    [PMID: 18205316]
    Bel-7402 IC50
    10.07 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human Bel7402 cells after 72 hrs by MTT assay
    Cytotoxicity against human Bel7402 cells after 72 hrs by MTT assay
    [PMID: 26227777]
    Bel-7402 IC50
    11.12 μM
    Compound: 5-FU
    Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
    Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
    [PMID: 24819956]
    Bel-7402 IC50
    11.78 μM
    Compound: 5-FU
    Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
    Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
    [PMID: 25529742]
    Bel-7402 IC50
    14.41 μM
    Compound: 5-FU
    Cytotoxicity against human BEL-7402 cells by MTT assay
    Cytotoxicity against human BEL-7402 cells by MTT assay
    [PMID: 18644718]
    Bel-7402 IC50
    14.91 μM
    Compound: 5-FU
    Antiproliferative activity against human Bel-7402 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay
    Antiproliferative activity against human Bel-7402 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay
    [PMID: 35290844]
    Bel-7402 IC50
    15.6 μM
    Compound: 5-FU
    Antiproliferative activity against human Bel7402 cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human Bel7402 cells incubated for 48 hrs by MTT assay
    [PMID: 30851694]
    Bel-7402 IC50
    17.59 μM
    Compound: 5-Fu
    Antiproliferative activity against human Bel7402 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human Bel7402 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 31202992]
    Bel-7402 IC50
    18.49 μM
    Compound: 5-FU
    Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
    Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
    [PMID: 29524728]
    Bel-7402 IC50
    18.49 μM
    Compound: 5-FU
    Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
    Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
    [PMID: 29407983]
    Bel-7402 IC50
    18.65 μM
    Compound: 5-FU
    Antiproliferative activity against human Bel7402 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human Bel7402 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 30921757]
    Bel-7402 IC50
    18.65 μM
    Compound: 5-FU
    Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
    Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
    [PMID: 30243153]
    Bel-7402 IC50
    18.97 μM
    Compound: 5-FU
    Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
    Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
    [PMID: 29635169]
    Bel-7402 IC50
    19.84 μM
    Compound: 5-Fu
    Antiproliferative activity against human Bel7402 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human Bel7402 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
    [PMID: 25113877]
    Bel-7402 IC50
    19.91 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human Bel7402 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
    Antiproliferative activity against human Bel7402 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
    [PMID: 25959813]
    Bel-7402 IC50
    2.23 μM
    Compound: 5-FU
    Cytotoxicity against human Bel7402 cells assessed as growth inhibition rate after 96 hrs by MTT assay
    Cytotoxicity against human Bel7402 cells assessed as growth inhibition rate after 96 hrs by MTT assay
    [PMID: 25203783]
    Bel-7402 IC50
    2.25 μM
    Compound: 5-Fu
    Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
    Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
    [PMID: 28165738]
    Bel-7402 IC50
    20.93 μM
    Compound: 5-Fu
    Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay
    Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay
    [PMID: 29174813]
    Bel-7402 IC50
    21.3 μM
    Compound: 5-Fu
    Antiproliferative activity against human Bel7402 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Antiproliferative activity against human Bel7402 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 30981113]
    Bel-7402 IC50
    214.33 μM
    Compound: 5-FU
    Antiproliferative activity in 5-FU resistant human Bel7402 cells after 72 hrs by MTT assay
    Antiproliferative activity in 5-FU resistant human Bel7402 cells after 72 hrs by MTT assay
    10.1039/C6MD00252H
    Bel-7402 IC50
    23.21 μM
    Compound: fluorouracil
    Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay
    Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay
    [PMID: 17291040]
    Bel-7402 IC50
    4.2 μM
    Compound: 5-Fu
    Cytotoxicity against human BEL-7402 cells after 96 hrs by MTT assay
    Cytotoxicity against human BEL-7402 cells after 96 hrs by MTT assay
    [PMID: 16499317]
    Bel-7402 IC50
    4.3 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human Bel7402 after 72 hrs by MTT assay
    Cytotoxicity against human Bel7402 after 72 hrs by MTT assay
    [PMID: 19233650]
    Bel-7402 IC50
    4.7 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human Bel7402 cells after 24 hrs by MTT assay
    Antiproliferative activity against human Bel7402 cells after 24 hrs by MTT assay
    [PMID: 19560842]
    Bel-7402 IC50
    5.5 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human Bel7402 cells after 4 days by MTT assay
    Cytotoxicity against human Bel7402 cells after 4 days by MTT assay
    [PMID: 24359303]
    Bel-7402 IC50
    5.94 μM
    Compound: 5-FU
    Antiproliferative activity against human Bel7402 cells after 72 hrs by CCK-8 assay
    Antiproliferative activity against human Bel7402 cells after 72 hrs by CCK-8 assay
    [PMID: 28301815]
    Bel-7402 IC50
    53.33 μM
    Compound: 5-FU
    Cytotoxicity against human Bel7402 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human Bel7402 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 31673307]
    Bel-7402 IC50
    7.36 μM
    Compound: 5-FU
    Antiproliferative activity against human Bel7402 incubated for 72 hrs by MTT assay
    Antiproliferative activity against human Bel7402 incubated for 72 hrs by MTT assay
    [PMID: 31553932]
    Bel-7402 IC50
    7.57 μM
    Compound: 5-FU
    Antiproliferative activity in human Bel7402 cells after 72 hrs by MTT assay
    Antiproliferative activity in human Bel7402 cells after 72 hrs by MTT assay
    10.1039/C6MD00252H
    Bel-7402 IC50
    8.3 μM
    Compound: 5-Fu
    Antiproliferative activity against human Bel7402 cells by MTT assay
    Antiproliferative activity against human Bel7402 cells by MTT assay
    [PMID: 24095094]
    Bel7402/5-FU IC50
    > 100 μM
    Compound: 5-FU
    Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by CCK-8 assay
    Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by CCK-8 assay
    [PMID: 28301815]
    Bel7402/5-FU IC50
    > 400 μM
    Compound: 5-FU
    Antiproliferative activity against human Bel7402/5-FU incubated for 72 hrs by MTT assay
    Antiproliferative activity against human Bel7402/5-FU incubated for 72 hrs by MTT assay
    [PMID: 31553932]
    Bel7402/5-FU IC50
    > 80 μM
    Compound: 5-FU
    Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by MTT assay
    Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by MTT assay
    [PMID: 29524728]
    Bel7402/5-FU IC50
    > 80 μM
    Compound: 5-FU
    Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by MTT assay
    Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by MTT assay
    [PMID: 29407983]
    Bel7402/5-FU IC50
    38.24 μM
    Compound: 5-FU
    Cytotoxicity against human Bel7402/5-FU cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human Bel7402/5-FU cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 31673307]
    Bel7402/5-FU IC50
    61.7 μM
    Compound: 5-FU
    Antiproliferative activity against human Bel7402/5-FU cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human Bel7402/5-FU cells incubated for 48 hrs by MTT assay
    [PMID: 30851694]
    Bel7402/5-FU IC50
    935.78 μM
    Compound: 5-FU
    Cytotoxicity against human Bel7402/5-FU cells after 72 hrs by MTT assay
    Cytotoxicity against human Bel7402/5-FU cells after 72 hrs by MTT assay
    [PMID: 30677614]
    BEL-7404 tumor cell line IC50
    0.2 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human Bel7404 after 24 hrs by MTT assay
    Cytotoxicity against human Bel7404 after 24 hrs by MTT assay
    [PMID: 19338315]
    BEL-7404 tumor cell line IC50
    26.8 μM
    Compound: 5-FU
    Cytotoxicity against human Bel7404 cells after 48 hrs by MTT assay
    Cytotoxicity against human Bel7404 cells after 48 hrs by MTT assay
    [PMID: 24565905]
    BEL-7404 tumor cell line IC50
    30.23 μM
    Compound: 5-FU
    Cytotoxic activity against human Bel7404 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
    Cytotoxic activity against human Bel7404 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
    [PMID: 26706349]
    BEL-7404 tumor cell line IC50
    40.21 μM
    Compound: 5-FU
    Cytotoxicity against human Bel7404 cells after 48 hrs by MTT assay
    Cytotoxicity against human Bel7404 cells after 48 hrs by MTT assay
    [PMID: 30092368]
    BGC-823 IC50
    0.2 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human BGC823 after 24 hrs by MTT assay
    Cytotoxicity against human BGC823 after 24 hrs by MTT assay
    [PMID: 19338315]
    BGC-823 IC50
    0.7 μg/mL
    Compound: 5-FU, 5-fluorouracil
    Cytotoxicity against human BGC 823 cells by MTT assay
    Cytotoxicity against human BGC 823 cells by MTT assay
    [PMID: 18205316]
    BGC-823 IC50
    1.52 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human BGC823 cells after 48 hrs by MTT method
    Antiproliferative activity against human BGC823 cells after 48 hrs by MTT method
    [PMID: 23018096]
    BGC-823 IC50
    100.02 μM
    Compound: 5-FU
    Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay
    Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay
    [PMID: 21962523]
    BGC-823 IC50
    14.02 μM
    Compound: 5-Fu
    Cytotoxicity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    [PMID: 34628244]
    BGC-823 IC50
    15.4 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human BGC-823 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay
    Cytotoxicity against human BGC-823 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay
    [PMID: 33799070]
    BGC-823 IC50
    15.65 μM
    Compound: 5-Fu
    Cytotoxicity against human BGC823 cells by MTT assay
    Cytotoxicity against human BGC823 cells by MTT assay
    [PMID: 22801644]
    BGC-823 EC50
    17.37 μg/mL
    Compound: 5-Fluorouracil
    Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay
    Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay
    [PMID: 21889345]
    BGC-823 IC50
    17.37 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay
    Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay
    [PMID: 28363444]
    BGC-823 IC50
    24.8 μM
    Compound: 5-Fu
    Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay
    Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay
    [PMID: 30527868]
    BGC-823 IC50
    3.84 μM
    Compound: 5-Fu
    Cytotoxicity against human BGC823 cells by MTT method
    Cytotoxicity against human BGC823 cells by MTT method
    [PMID: 23164710]
    BGC-823 IC50
    31.16 μM
    Compound: fluorouracil
    Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay
    Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay
    [PMID: 17291040]
    BGC-823 IC50
    34.8 μM
    Compound: 5-FU
    Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay
    Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay
    [PMID: 30108895]
    BGC-823 IC50
    34.8 μM
    Compound: 5-Fu
    Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay
    Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay
    [PMID: 28073676]
    BGC-823 IC50
    35.6 μM
    Compound: 5-Fu
    Antiproliferative activity against human BGC823 cells assessed as cell-growth inhibition after 48 hrs by MTT assay
    Antiproliferative activity against human BGC823 cells assessed as cell-growth inhibition after 48 hrs by MTT assay
    [PMID: 25453794]
    BGC-823 IC50
    37 μM
    Compound: 5-Fu
    Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay
    Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay
    10.1039/C5MD00382B
    BGC-823 IC50
    4.5 μM
    Compound: 5-FU
    Cytotoxicity against human BGC823 cells after 72 hrs by MTT assay
    Cytotoxicity against human BGC823 cells after 72 hrs by MTT assay
    [PMID: 22727445]
    BGC-823 IC50
    5.4 μM
    Compound: 5-Fu
    Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay
    Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay
    [PMID: 16499317]
    BGC-823 IC50
    5.89 μM
    Compound: 5-Fu
    Antiproliferative activity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Antiproliferative activity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    [PMID: 32682202]
    BGC-823 IC50
    7.48 μM
    Compound: 5-FU
    Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay
    Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay
    [PMID: 24286761]
    BGC-823 IC50
    8.2 μg/mL
    Compound: 5-FU
    Cytotoxicity against human BGC823 cells after 72 hrs by MTT assay
    Cytotoxicity against human BGC823 cells after 72 hrs by MTT assay
    [PMID: 22647218]
    BGC-823 IC50
    8.82 μM
    Compound: 5-FU
    Cytotoxicity against human BGC823 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    Cytotoxicity against human BGC823 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    10.1039/C6MD00061D
    BT-20 IC50
    47.3 μM
    Compound: 5FU
    Cytotoxicity against human BT20 cells incubated for 72 hrs by SRB assay
    Cytotoxicity against human BT20 cells incubated for 72 hrs by SRB assay
    [PMID: 22867707]
    BT-474 IC50
    72.9 μM
    Compound: 5-Fu
    Cytotoxicity against human BT474 cells after 3 days by MTT assay
    Cytotoxicity against human BT474 cells after 3 days by MTT assay
    [PMID: 22000925]
    BT-549 GI50
    10.6 μM
    Compound: 5-FU
    Anticancer activity against human BT-549 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human BT-549 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    BT-549 GI50
    10.6 μM
    Compound: 5-FU
    Growth inhibition of human BT549 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human BT549 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    BT-549 IC50
    19.82 μM
    Compound: 5-FU
    Cytotoxicity against human BT549 cells after 48 hrs by MTT assay
    Cytotoxicity against human BT549 cells after 48 hrs by MTT assay
    [PMID: 27397498]
    BT-549 IC50
    19.82 μM
    Compound: 5-FU
    Anticancer activity against human BT549 cells after 48 hrs by MTT assay
    Anticancer activity against human BT549 cells after 48 hrs by MTT assay
    [PMID: 26413726]
    BT-549 IC50
    98.24 μM
    Compound: Fluorouracil
    Cytotoxicity against human BT549 cells after 48 hrs by MTT assay
    Cytotoxicity against human BT549 cells after 48 hrs by MTT assay
    [PMID: 28789892]
    BXPC-3 EC50
    0.14 μM
    Compound: 1; 5-FU
    Antiproliferative activity against human BxPC-3 cells assessed as reduction in cell viability measured after 5 days by PrestoBlue reagent based assay
    Antiproliferative activity against human BxPC-3 cells assessed as reduction in cell viability measured after 5 days by PrestoBlue reagent based assay
    [PMID: 34979089]
    BXPC-3 GI50
    2.9 nM
    Compound: 5FU
    Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay
    Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay
    [PMID: 23094992]
    BXPC-3 GI50
    8.2 μM
    Compound: 5-Fu
    Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay
    Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay
    [PMID: 22512908]
    C13 IC50
    12.1 μM
    Compound: 5FU
    Cytotoxicity against human C13 cells after 72 hrs
    Cytotoxicity against human C13 cells after 72 hrs
    [PMID: 30035541]
    C13 IC50
    8.5 μM
    Compound: 1, 5-FU
    Growth inhibition of cDDP-resistant human C13 cells by crystal violet assay
    Growth inhibition of cDDP-resistant human C13 cells by crystal violet assay
    [PMID: 23075414]
    C170 IC50
    0.3 μg/mL
    Compound: 5-FU
    Tested for cytotoxicity against C170 colorectal carcinoma cell line by [75Se]selenomethionine uptake assay, in vitro
    Tested for cytotoxicity against C170 colorectal carcinoma cell line by [75Se]selenomethionine uptake assay, in vitro
    [PMID: 8496926]
    C170 IC50
    2 μM
    Compound: 5-FU
    Tested for cytotoxicity against C170 colorectal carcinoma cell line by [75Se]selenomethionine uptake assay, in vitro
    Tested for cytotoxicity against C170 colorectal carcinoma cell line by [75Se]selenomethionine uptake assay, in vitro
    [PMID: 8496926]
    C-33-A IC50
    4.61 μM
    Compound: 5-FU
    Cytotoxicity against human C33A cells assessed as growth inhibition rate after 96 hrs by MTT assay
    Cytotoxicity against human C33A cells assessed as growth inhibition rate after 96 hrs by MTT assay
    [PMID: 25203783]
    Ca9-22 CC50
    13 μM
    Compound: 5-FU
    Cytotoxicity against human Ca9-22 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human Ca9-22 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 32795767]
    Ca9-22 CC50
    262 μM
    Compound: 5-FU
    Cytotoxicity against human Ca9-22 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human Ca9-22 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 31532650]
    Caco-2 IC50
    1.5 μM
    Compound: 5-Fu
    Growth inhibition of human Caco-2 cells after 10 days
    Growth inhibition of human Caco-2 cells after 10 days
    [PMID: 18037195]
    Caco-2 IC50
    1.5 μM
    Compound: 5FU
    Growth inhibition of human Caco-2 cells after 10 days
    Growth inhibition of human Caco-2 cells after 10 days
    [PMID: 17555969]
    Caco-2 IC50
    1.5 μM
    Compound: 5-FU
    Growth inhibition of human Caco-2 cells after 10 days
    Growth inhibition of human Caco-2 cells after 10 days
    [PMID: 17337193]
    Caco-2 GI50
    2.2 μM
    Compound: 5-FU
    Antiproliferative activity against human Caco2 cells after 72 hrs by MTT-based Mosmann assay relative to control
    Antiproliferative activity against human Caco2 cells after 72 hrs by MTT-based Mosmann assay relative to control
    [PMID: 26539626]
    Caco-2 IC50
    21 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against Homo sapiens (human) Caco2 cells after 48 hr by SRB assay
    Cytotoxicity against Homo sapiens (human) Caco2 cells after 48 hr by SRB assay
    10.1007/s00044-012-0424-0
    Caco-2 IC50
    21 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human Caco2 cells assessed as inhibition of cell proliferation after 48 hrs by sulforhodamine-B assay
    Cytotoxicity against human Caco2 cells assessed as inhibition of cell proliferation after 48 hrs by sulforhodamine-B assay
    10.1039/C3MD00055A
    Caco-2 GI50
    3.3 μM
    Compound: 5-FU
    Growth inhibition of human Caco2 cells measured after 72 hrs by MTT assay
    Growth inhibition of human Caco2 cells measured after 72 hrs by MTT assay
    [PMID: 27504537]
    Caco-2 IC50
    31 μM
    Compound: 5-FU
    Cytotoxicity against human Caco2 cells assessed as cell viability after 24 hrs by MTT assay
    Cytotoxicity against human Caco2 cells assessed as cell viability after 24 hrs by MTT assay
    [PMID: 28463785]
    Caco-2 IC50
    38.77 μM
    Compound: 5-FU
    Antiproliferative activity against human Caco2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human Caco2 cells after 72 hrs by MTT assay
    [PMID: 29635169]
    Caco-2 CC50
    384.4 μM
    Compound: 5-Fu
    Cytotoxicity against human Caco-2 cells after 72 hrs
    Cytotoxicity against human Caco-2 cells after 72 hrs
    [PMID: 18037195]
    Caco-2 CC50
    384.4 μM
    Compound: 5FU
    Cytotoxicity against human Caco-2 cells after 72 hrs
    Cytotoxicity against human Caco-2 cells after 72 hrs
    [PMID: 17555969]
    Caco-2 CC50
    384.4 μM
    Compound: 5FU
    Cytotoxicity against human Caco-2 cells after 72 hrs
    Cytotoxicity against human Caco-2 cells after 72 hrs
    [PMID: 17548129]
    Caco-2 CC50
    384.4 μM
    Compound: 5-FU
    Cytotoxicity against human Caco-2 cells after 72 hrs
    Cytotoxicity against human Caco-2 cells after 72 hrs
    [PMID: 17337193]
    Caco-2 IC50
    60 μM
    Compound: 5-Fluorouracil
    Cytotoxicity in human Caco2 cells after 72 hrs by MTT assay
    Cytotoxicity in human Caco2 cells after 72 hrs by MTT assay
    [PMID: 28793973]
    Caco-2 IC50
    7.77 μM
    Compound: 5-FU
    Cytotoxicity against human Caco-2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    Cytotoxicity against human Caco-2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    [PMID: 34170142]
    Caco-2 IC50
    7.8 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human Caco2 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay
    Cytotoxicity against human Caco2 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay
    [PMID: 33799070]
    CAKI-1 GI50
    0.07 μM
    Compound: 5-FU
    Anticancer activity against human CAKI-1 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human CAKI-1 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    CAKI-1 GI50
    0.07 μM
    Compound: 5-FU
    Growth inhibition of human CAKI-1 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human CAKI-1 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    CAL-27 IC50
    0.5 μg/mL
    Compound: 5-FU
    Antiproliferative activity against human CAL-27 cells assessed as cell viability measured after 72 hrs by MTT assay
    Antiproliferative activity against human CAL-27 cells assessed as cell viability measured after 72 hrs by MTT assay
    [PMID: 34463097]
    CAMA-1 IC50
    1.28 μM
    Compound: 5FU
    Cytotoxicity against human CAMA1 cells incubated for 72 hrs by SRB assay
    Cytotoxicity against human CAMA1 cells incubated for 72 hrs by SRB assay
    [PMID: 22867707]
    Cancer cell lines GI50
    > 100 μM
    Compound: 5-FU
    Cytotoxicity against human non-small cell lung cancer cells after 48 hrs by coulter counter analysis
    Cytotoxicity against human non-small cell lung cancer cells after 48 hrs by coulter counter analysis
    [PMID: 23683592]
    Cancer cell lines GI50
    > 100 μM
    Compound: 5-FU
    Growth inhibition of human non-small cell lung cancer cells after 48 hrs by SRB assay
    Growth inhibition of human non-small cell lung cancer cells after 48 hrs by SRB assay
    [PMID: 27554444]
    Cancer cell lines GI50
    > 100 μM
    Compound: 5-FU
    Cytotoxicity against human non-small cell lung cancer cells after 48 hrs by SRB assay
    Cytotoxicity against human non-small cell lung cancer cells after 48 hrs by SRB assay
    [PMID: 23994328]
    Cancer cell lines GI50
    > 100 μM
    Compound: 5-fu
    Antitumor activity against human non small cell lung cancer cells after 48 hrs by SRB assay
    Antitumor activity against human non small cell lung cancer cells after 48 hrs by SRB assay
    [PMID: 20350811]
    Cancer cell lines GI50
    > 100 μM
    Compound: 5-FU
    Cytotoxicity against human non-small cell lung cancer cells at 10 uM after 48 hrs
    Cytotoxicity against human non-small cell lung cancer cells at 10 uM after 48 hrs
    [PMID: 24469112]
    Cancer cell lines GI50
    > 100 μM
    Compound: 5-FU
    Cytotoxicity against human non-small cell lung cancer cells after 48 hrs by sulphorhodamine B assay
    Cytotoxicity against human non-small cell lung cancer cells after 48 hrs by sulphorhodamine B assay
    [PMID: 23474899]
    Cancer cell lines GI50
    > 100 μM
    Compound: 5-fu
    Antiproliferative activity against human non-small cell lung cancer cells after 48 hrs by cell counting analysis
    Antiproliferative activity against human non-small cell lung cancer cells after 48 hrs by cell counting analysis
    [PMID: 22995621]
    Cancer cell lines IC50
    2.3 μM
    Compound: 5-Florouracil
    Anticancer activity against Homo sapiens (human) NCI lung cancer cell assessed as inhibition of cell proliferation after 24 hr by MTT assay
    Anticancer activity against Homo sapiens (human) NCI lung cancer cell assessed as inhibition of cell proliferation after 24 hr by MTT assay
    10.1007/s00044-012-0260-2
    Cancer cell lines GI50
    22.7 μM
    Compound: 5-FU
    Cytotoxicity against human prostate cancer cells after 48 hrs by coulter counter analysis
    Cytotoxicity against human prostate cancer cells after 48 hrs by coulter counter analysis
    [PMID: 23683592]
    Cancer cell lines GI50
    22.7 μM
    Compound: 5-FU
    Growth inhibition of human prostate cancer cells after 48 hrs by coulter counter method
    Growth inhibition of human prostate cancer cells after 48 hrs by coulter counter method
    [PMID: 22119151]
    Cancer cell lines GI50
    22.7 μM
    Compound: 5-FU
    Cytotoxicity against human prostate cancer cells after 48 hrs by coulter counting
    Cytotoxicity against human prostate cancer cells after 48 hrs by coulter counting
    [PMID: 22056277]
    Cancer cell lines GI50
    22.7 μM
    Compound: 5-FU
    Growth inhibition of human prostate cancer cells after 48 hrs by SRB assay
    Growth inhibition of human prostate cancer cells after 48 hrs by SRB assay
    [PMID: 27554444]
    Cancer cell lines GI50
    22.7 μM
    Compound: 5-FU
    Cytotoxicity against human prostate cancer cells after 48 hrs by SRB assay
    Cytotoxicity against human prostate cancer cells after 48 hrs by SRB assay
    [PMID: 23994328]
    Cancer cell lines GI50
    22.7 μM
    Compound: 5-fu
    Antitumor activity against human prostate cancer cells after 48 hrs by SRB assay
    Antitumor activity against human prostate cancer cells after 48 hrs by SRB assay
    [PMID: 20350811]
    Cancer cell lines GI50
    22.7 μM
    Compound: 5-FU
    Cytotoxicity against human prostate cancer cells at 10 uM after 48 hrs
    Cytotoxicity against human prostate cancer cells at 10 uM after 48 hrs
    [PMID: 24469112]
    Cancer cell lines GI50
    22.7 μM
    Compound: 5-FU
    Cytotoxicity against human prostate cancer cells after 48 hrs by sulphorhodamine B assay
    Cytotoxicity against human prostate cancer cells after 48 hrs by sulphorhodamine B assay
    [PMID: 23474899]
    Cancer cell lines GI50
    22.7 μM
    Compound: 5-fu
    Antiproliferative activity against human prostate cancer cells after 48 hrs by cell counting analysis
    Antiproliferative activity against human prostate cancer cells after 48 hrs by cell counting analysis
    [PMID: 22995621]
    Cancer cell lines GI50
    22.7 μM
    Compound: 5-FU
    Growth inhibition of human prostate cancer cells after 48 hrs
    Growth inhibition of human prostate cancer cells after 48 hrs
    [PMID: 18950904]
    Cancer cell lines IC50
    3.6 μM
    Compound: 5-FU
    Antiproliferative activity was evaluated against human prostate TSU cancer cell lines using the sulforhodamine B (STB) assay
    Antiproliferative activity was evaluated against human prostate TSU cancer cell lines using the sulforhodamine B (STB) assay
    [PMID: 15454213]
    Cancer cell lines GI50
    45.6 μM
    Compound: 5-FU
    Cytotoxicity against human renal cancer cells after 48 hrs by coulter counter analysis
    Cytotoxicity against human renal cancer cells after 48 hrs by coulter counter analysis
    [PMID: 23683592]
    Cancer cell lines GI50
    45.6 μM
    Compound: 5-FU
    Growth inhibition of human renal cancer cells after 48 hrs by coulter counter method
    Growth inhibition of human renal cancer cells after 48 hrs by coulter counter method
    [PMID: 22119151]
    Cancer cell lines GI50
    45.6 μM
    Compound: 5-FU
    Cytotoxicity against human renal cancer cells after 48 hrs by coulter counting
    Cytotoxicity against human renal cancer cells after 48 hrs by coulter counting
    [PMID: 22056277]
    Cancer cell lines GI50
    45.6 μM
    Compound: 5-FU
    Growth inhibition of human renal cancer cells after 48 hrs by SRB assay
    Growth inhibition of human renal cancer cells after 48 hrs by SRB assay
    [PMID: 27554444]
    Cancer cell lines GI50
    45.6 μM
    Compound: 5-FU
    Cytotoxicity against human renal cancer cells after 48 hrs by SRB assay
    Cytotoxicity against human renal cancer cells after 48 hrs by SRB assay
    [PMID: 23994328]
    Cancer cell lines GI50
    45.6 μM
    Compound: 5-fu
    Antitumor activity against human renal cancer cells after 48 hrs by SRB assay
    Antitumor activity against human renal cancer cells after 48 hrs by SRB assay
    [PMID: 20350811]
    Cancer cell lines GI50
    45.6 μM
    Compound: 5-FU
    Cytotoxicity against human renal cancer cells at 10 uM after 48 hrs
    Cytotoxicity against human renal cancer cells at 10 uM after 48 hrs
    [PMID: 24469112]
    Cancer cell lines GI50
    45.6 μM
    Compound: 5-FU
    Cytotoxicity against human renal cancer cells after 48 hrs by sulphorhodamine B assay
    Cytotoxicity against human renal cancer cells after 48 hrs by sulphorhodamine B assay
    [PMID: 23474899]
    Cancer cell lines GI50
    45.6 μM
    Compound: 5-fu
    Antiproliferative activity against human renal cancer cells after 48 hrs by cell counting analysis
    Antiproliferative activity against human renal cancer cells after 48 hrs by cell counting analysis
    [PMID: 22995621]
    Cancer cell lines GI50
    45.6 μM
    Compound: 5-FU
    Growth inhibition of human renal cancer cells after 48 hrs
    Growth inhibition of human renal cancer cells after 48 hrs
    [PMID: 18950904]
    Cancer cell lines IC50
    6.4 μM
    Compound: 5-FU
    Antiproliferative activity was evaluated against human prostate PPC-1 cancer cell lines using the sulforhodamine B (STB) assay
    Antiproliferative activity was evaluated against human prostate PPC-1 cancer cell lines using the sulforhodamine B (STB) assay
    [PMID: 15454213]
    Cancer cell lines GI50
    61.4 μM
    Compound: 5-FU
    Cytotoxicity against human ovarian cancer cells after 48 hrs by coulter counter analysis
    Cytotoxicity against human ovarian cancer cells after 48 hrs by coulter counter analysis
    [PMID: 23683592]
    Cancer cell lines GI50
    61.4 μM
    Compound: 5-FU
    Growth inhibition of human ovarian cancer cells after 48 hrs by coulter counter method
    Growth inhibition of human ovarian cancer cells after 48 hrs by coulter counter method
    [PMID: 22119151]
    Cancer cell lines GI50
    61.4 μM
    Compound: 5-FU
    Cytotoxicity against human ovarian cancer cells after 48 hrs by coulter counting
    Cytotoxicity against human ovarian cancer cells after 48 hrs by coulter counting
    [PMID: 22056277]
    Cancer cell lines GI50
    61.4 μM
    Compound: 5-FU
    Growth inhibition of human ovarian cancer cells after 48 hrs by SRB assay
    Growth inhibition of human ovarian cancer cells after 48 hrs by SRB assay
    [PMID: 27554444]
    Cancer cell lines GI50
    61.4 μM
    Compound: 5-FU
    Cytotoxicity against human ovarian cancer cells after 48 hrs by SRB assay
    Cytotoxicity against human ovarian cancer cells after 48 hrs by SRB assay
    [PMID: 23994328]
    Cancer cell lines GI50
    61.4 μM
    Compound: 5-fu
    Antitumor activity against human ovarian cancer cells after 48 hrs by SRB assay
    Antitumor activity against human ovarian cancer cells after 48 hrs by SRB assay
    [PMID: 20350811]
    Cancer cell lines GI50
    61.4 μM
    Compound: 5-FU
    Cytotoxicity against human ovarian cancer cells at 10 uM after 48 hrs
    Cytotoxicity against human ovarian cancer cells at 10 uM after 48 hrs
    [PMID: 24469112]
    Cancer cell lines GI50
    61.4 μM
    Compound: 5-FU
    Cytotoxicity against human ovarian cancer cells after 48 hrs by sulphorhodamine B assay
    Cytotoxicity against human ovarian cancer cells after 48 hrs by sulphorhodamine B assay
    [PMID: 23474899]
    Cancer cell lines GI50
    61.4 μM
    Compound: 5-fu
    Antiproliferative activity against human ovarian cancer cells after 48 hrs by cell counting analysis
    Antiproliferative activity against human ovarian cancer cells after 48 hrs by cell counting analysis
    [PMID: 22995621]
    Cancer cell lines GI50
    61.4 μM
    Compound: 5-FU
    Growth inhibition of human ovarian cancer cells after 48 hrs
    Growth inhibition of human ovarian cancer cells after 48 hrs
    [PMID: 18950904]
    Cancer cell lines GI50
    72.07 μM
    Compound: 5-FU
    Growth inhibition of human CNS cancer cells after 48 hrs
    Growth inhibition of human CNS cancer cells after 48 hrs
    [PMID: 18950904]
    Cancer cell lines GI50
    72.1 μM
    Compound: 5-FU
    Cytotoxicity against human CNS cancer cells after 48 hrs by coulter counter analysis
    Cytotoxicity against human CNS cancer cells after 48 hrs by coulter counter analysis
    [PMID: 23683592]
    Cancer cell lines GI50
    72.1 μM
    Compound: 5-FU
    Growth inhibition of human CNS cancer cells after 48 hrs by coulter counter method
    Growth inhibition of human CNS cancer cells after 48 hrs by coulter counter method
    [PMID: 22119151]
    Cancer cell lines GI50
    72.1 μM
    Compound: 5-FU
    Cytotoxicity against human CNS cancer cells after 48 hrs by coulter counting
    Cytotoxicity against human CNS cancer cells after 48 hrs by coulter counting
    [PMID: 22056277]
    Cancer cell lines GI50
    72.1 μM
    Compound: 5-FU
    Growth inhibition of human CNS cancer cells after 48 hrs by SRB assay
    Growth inhibition of human CNS cancer cells after 48 hrs by SRB assay
    [PMID: 27554444]
    Cancer cell lines GI50
    72.1 μM
    Compound: 5-FU
    Cytotoxicity against human CNS cancer cells after 48 hrs by SRB assay
    Cytotoxicity against human CNS cancer cells after 48 hrs by SRB assay
    [PMID: 23994328]
    Cancer cell lines GI50
    72.1 μM
    Compound: 5-fu
    Antitumor activity against human CNS cancer cells after 48 hrs by SRB assay
    Antitumor activity against human CNS cancer cells after 48 hrs by SRB assay
    [PMID: 20350811]
    Cancer cell lines GI50
    72.1 μM
    Compound: 5-FU
    Cytotoxicity against human CNS cancer cells at 10 uM after 48 hrs
    Cytotoxicity against human CNS cancer cells at 10 uM after 48 hrs
    [PMID: 24469112]
    Cancer cell lines GI50
    72.1 μM
    Compound: 5-FU
    Cytotoxicity against human CNS cancer cells after 48 hrs by sulphorhodamine B assay
    Cytotoxicity against human CNS cancer cells after 48 hrs by sulphorhodamine B assay
    [PMID: 23474899]
    Cancer cell lines GI50
    72.1 μM
    Compound: 5-fu
    Antiproliferative activity against human CNS cancer cells after 48 hrs by cell counting analysis
    Antiproliferative activity against human CNS cancer cells after 48 hrs by cell counting analysis
    [PMID: 22995621]
    Cancer cell lines GI50
    76.4 μM
    Compound: 5-FU
    Cytotoxicity against human breast cancer cells after 48 hrs by coulter counter analysis
    Cytotoxicity against human breast cancer cells after 48 hrs by coulter counter analysis
    [PMID: 23683592]
    Cancer cell lines GI50
    76.4 μM
    Compound: 5-FU
    Growth inhibition of human breast cancer cells after 48 hrs by coulter counter method
    Growth inhibition of human breast cancer cells after 48 hrs by coulter counter method
    [PMID: 22119151]
    Cancer cell lines GI50
    76.4 μM
    Compound: 5-FU
    Cytotoxicity against human breast cancer cells after 48 hrs by coulter counting
    Cytotoxicity against human breast cancer cells after 48 hrs by coulter counting
    [PMID: 22056277]
    Cancer cell lines GI50
    76.4 μM
    Compound: 5-FU
    Growth inhibition of human breast cancer cells after 48 hrs by SRB assay
    Growth inhibition of human breast cancer cells after 48 hrs by SRB assay
    [PMID: 27554444]
    Cancer cell lines GI50
    76.4 μM
    Compound: 5-FU
    Cytotoxicity against human breast cancer cells after 48 hrs by SRB assay
    Cytotoxicity against human breast cancer cells after 48 hrs by SRB assay
    [PMID: 23994328]
    Cancer cell lines GI50
    76.4 μM
    Compound: 5-fu
    Antitumor activity against human breast cancer cells after 48 hrs by SRB assay
    Antitumor activity against human breast cancer cells after 48 hrs by SRB assay
    [PMID: 20350811]
    Cancer cell lines GI50
    76.4 μM
    Compound: 5-FU
    Cytotoxicity against human breast cancer cells at 10 uM after 48 hrs
    Cytotoxicity against human breast cancer cells at 10 uM after 48 hrs
    [PMID: 24469112]
    Cancer cell lines GI50
    76.4 μM
    Compound: 5-FU
    Cytotoxicity against human breast cancer cells after 48 hrs by sulphorhodamine B assay
    Cytotoxicity against human breast cancer cells after 48 hrs by sulphorhodamine B assay
    [PMID: 23474899]
    Cancer cell lines GI50
    76.4 μM
    Compound: 5-fu
    Antiproliferative activity against human breast cancer cells after 48 hrs by cell counting analysis
    Antiproliferative activity against human breast cancer cells after 48 hrs by cell counting analysis
    [PMID: 22995621]
    Cancer cell lines GI50
    76.4 μM
    Compound: 5-FU
    Growth inhibition of human breast cancer cells after 48 hrs
    Growth inhibition of human breast cancer cells after 48 hrs
    [PMID: 18950904]
    Cancer cell lines GI50
    8.37 μM
    Compound: 5-FU
    Growth inhibition of human Colon cancer cells after 48 hrs
    Growth inhibition of human Colon cancer cells after 48 hrs
    [PMID: 18950904]
    Cancer cell lines GI50
    8.4 μM
    Compound: 5-FU
    Cytotoxicity against human colon cancer cells after 48 hrs by coulter counter analysis
    Cytotoxicity against human colon cancer cells after 48 hrs by coulter counter analysis
    [PMID: 23683592]
    Cancer cell lines GI50
    8.4 μM
    Compound: 5-FU
    Growth inhibition of human colon cancer cells after 48 hrs by coulter counter method
    Growth inhibition of human colon cancer cells after 48 hrs by coulter counter method
    [PMID: 22119151]
    Cancer cell lines GI50
    8.4 μM
    Compound: 5-FU
    Cytotoxicity against human colon cancer cells after 48 hrs by coulter counting
    Cytotoxicity against human colon cancer cells after 48 hrs by coulter counting
    [PMID: 22056277]
    Cancer cell lines GI50
    8.4 μM
    Compound: 5-FU
    Growth inhibition of human colon cancer cells after 48 hrs by SRB assay
    Growth inhibition of human colon cancer cells after 48 hrs by SRB assay
    [PMID: 27554444]
    Cancer cell lines GI50
    8.4 μM
    Compound: 5-FU
    Cytotoxicity against human colon cancer cells after 48 hrs by SRB assay
    Cytotoxicity against human colon cancer cells after 48 hrs by SRB assay
    [PMID: 23994328]
    Cancer cell lines GI50
    8.4 μM
    Compound: 5-fu
    Antitumor activity against human colon cancer cells after 48 hrs by SRB assay
    Antitumor activity against human colon cancer cells after 48 hrs by SRB assay
    [PMID: 20350811]
    Cancer cell lines GI50
    8.4 μM
    Compound: 5-FU
    Cytotoxicity against human colon cancer cells at 10 uM after 48 hrs
    Cytotoxicity against human colon cancer cells at 10 uM after 48 hrs
    [PMID: 24469112]
    Cancer cell lines GI50
    8.4 μM
    Compound: 5-FU
    Cytotoxicity against human colon cancer cells after 48 hrs by sulphorhodamine B assay
    Cytotoxicity against human colon cancer cells after 48 hrs by sulphorhodamine B assay
    [PMID: 23474899]
    Cancer cell lines GI50
    8.4 μM
    Compound: 5-fu
    Antiproliferative activity against human colon cancer cells after 48 hrs by cell counting analysis
    Antiproliferative activity against human colon cancer cells after 48 hrs by cell counting analysis
    [PMID: 22995621]
    CAPAN-1 IC50
    0.47 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human Capan-1 cells assessed as reduction in cell growth incubated for 72 hrs by SRB assay
    Antiproliferative activity against human Capan-1 cells assessed as reduction in cell growth incubated for 72 hrs by SRB assay
    [PMID: 32007666]
    Capan-2 IC50
    54.247 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human Capan2 cells incubated for 24 hrs by MTT assay
    Cytotoxicity against human Capan2 cells incubated for 24 hrs by MTT assay
    [PMID: 30904782]
    CCD-18Co IC50
    > 200 μM
    Compound: 5-FU
    Cytotoxicity against human CCD-18Co cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human CCD-18Co cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 32203786]
    CCD-18Co IC50
    9.26 μM
    Compound: 5-Fu
    Cytotoxicity against human CCD-18Co cells after 3 days by SRB assay
    Cytotoxicity against human CCD-18Co cells after 3 days by SRB assay
    [PMID: 24704691]
    CCD-841CoN IC50
    > 25 μM
    Compound: 5-FU
    Antiproliferative activity against human CRL1790 cells assessed as inhibition cell proliferation after 48 hrs by Sulforhodamine B assay
    Antiproliferative activity against human CRL1790 cells assessed as inhibition cell proliferation after 48 hrs by Sulforhodamine B assay
    [PMID: 23305919]
    CCD-841CoN GI50
    10.3 μM
    Compound: 5-FU
    Cytotoxicity against human CRL1790 cells assessed as reduction in cell viability after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human CRL1790 cells assessed as reduction in cell viability after 48 hrs by sulforhodamine B assay
    [PMID: 28716495]
    CCD-841CoN EC50
    218 μM
    Compound: 5FU
    Cytotoxicity against human CCD-841CoN cells assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay
    Cytotoxicity against human CCD-841CoN cells assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay
    [PMID: 35939803]
    CCD-841CoN IC50
    35.7 μM
    Compound: 5-FU
    Antiproliferative activity against human CCD-841-CoN cells after 72 hrs by MTT assay
    Antiproliferative activity against human CCD-841-CoN cells after 72 hrs by MTT assay
    [PMID: 30037494]
    CCRF-CEM IC50
    12 μM
    Compound: 1, 5-FU
    Cytostatic activity against thymidine-kinase deficient human CEM cells after 72 hrs by cell counting
    Cytostatic activity against thymidine-kinase deficient human CEM cells after 72 hrs by cell counting
    [PMID: 21892829]
    CCRF-CEM IC50
    125 μM
    Compound: 5-FU
    Antiproliferative activity against human CEM cells after 72 hrs by MTT assay
    Antiproliferative activity against human CEM cells after 72 hrs by MTT assay
    [PMID: 19743863]
    CCRF-CEM IC50
    14 μM
    Compound: 5-FU
    Cytostatic activity against human CEM cells after 3 days by coulter counting analysis
    Cytostatic activity against human CEM cells after 3 days by coulter counting analysis
    [PMID: 21330014]
    CCRF-CEM IC50
    14 μM
    Compound: 5-FU
    Cytotoxicity against human CEM cells after 3 days by coulter counter analysis
    Cytotoxicity against human CEM cells after 3 days by coulter counter analysis
    [PMID: 21232828]
    CCRF-CEM IC50
    15 μM
    Compound: 5-FU
    Cytotoxicity against human CEM cells after 48 hrs by trypan blue assay
    Cytotoxicity against human CEM cells after 48 hrs by trypan blue assay
    [PMID: 21439690]
    CCRF-CEM IC50
    18 μM
    Compound: 5-Fluorouracil
    Cytostatic activity against human CEM cells after 3 days by coulter counter analysis
    Cytostatic activity against human CEM cells after 3 days by coulter counter analysis
    [PMID: 22405290]
    CCRF-CEM IC50
    18 μM
    Compound: 5-Fluorouracil
    Anti-proliferative activity against human CEM cells measured after 72 hrs by coulter counter method
    Anti-proliferative activity against human CEM cells measured after 72 hrs by coulter counter method
    [PMID: 27750154]
    CCRF-CEM IC50
    18 μM
    Compound: 5-FU
    Cytostatic activity against human CEM cells after 72 hrs by Coulter counting
    Cytostatic activity against human CEM cells after 72 hrs by Coulter counting
    [PMID: 25435471]
    CCRF-CEM IC50
    18 μM
    Compound: 5-Fluorouracil
    Cytostatic activity against human CEM cells assessed as inhibition of proliferation after 72 hrs by Coulter cell counting method
    Cytostatic activity against human CEM cells assessed as inhibition of proliferation after 72 hrs by Coulter cell counting method
    [PMID: 24906510]
    CCRF-CEM IC50
    18 μM
    Compound: 5FU
    Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell number after 72 hrs by cell counting assay
    Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell number after 72 hrs by cell counting assay
    [PMID: 24631358]
    CCRF-CEM IC50
    18 μM
    Compound: 1, 5-FU
    Cytostatic activity against human CEM/0 cells after 72 hrs by cell counting
    Cytostatic activity against human CEM/0 cells after 72 hrs by cell counting
    [PMID: 21892829]
    CCRF-CEM IC50
    30 μM
    Compound: 5-FU
    Cytotoxicity against human CEM cells after 72 hrs by MTT assay
    Cytotoxicity against human CEM cells after 72 hrs by MTT assay
    [PMID: 21439690]
    CCRF-CEM IC50
    32 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human CEM cells after 72 hrs by MTT assay
    Cytotoxicity against human CEM cells after 72 hrs by MTT assay
    [PMID: 23535322]
    CCRF-CEM IC50
    4 μg/mL
    Compound: 5-FU
    The compound was evaluated for antitumoral activity against human leukemia cell line CCRF CEM after 72 hr of incubation
    The compound was evaluated for antitumoral activity against human leukemia cell line CCRF CEM after 72 hr of incubation
    10.1016/S0960-894X(01)80742-3
    CCRF-CEM IC50
    40 μM
    Compound: 5-FU
    Cytotoxicity against human CEM cells after 48 hrs by MTT assay
    Cytotoxicity against human CEM cells after 48 hrs by MTT assay
    [PMID: 21439690]
    CCRF-CEM IC50
    8 μM
    Compound: 5-FU
    Cytotoxicity against human CEM cells after 72 hrs by trypan blue assay
    Cytotoxicity against human CEM cells after 72 hrs by trypan blue assay
    [PMID: 21439690]
    CCRF-CEM IC50
    9.23 μM
    Compound: 5-FU
    Antiproliferative activity against human CEM cells after 3 days by MTT assay
    Antiproliferative activity against human CEM cells after 3 days by MTT assay
    [PMID: 18424155]
    CCRF-CEM GI50
    9.79 μM
    Compound: 5-FU
    Growth inhibition of human CCRF-CEM cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human CCRF-CEM cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    CCRF-CEM GI50
    9.97 μM
    Compound: 5-FU
    Anticancer activity against human CCRF-CEM cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human CCRF-CEM cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    CFPAC-1 IC50
    0.14 μM
    Compound: 5-FU
    Antiproliferative activity against human CFPAC-1 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human CFPAC-1 cells incubated for 72 hrs by MTT assay
    [PMID: 31734024]
    CFPAC-1 IC50
    0.14 μM
    Compound: 5-FU
    Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay
    Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay
    [PMID: 29133046]
    CFPAC-1 IC50
    0.14 μM
    Compound: 5-FU
    Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay
    Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay
    [PMID: 28525845]
    CFPAC-1 IC50
    0.14 μM
    Compound: 5-FU
    Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay
    Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay
    [PMID: 27875779]
    CFPAC-1 IC50
    41.221 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human CFPAC-1 cells incubated for 24 hrs by MTT assay
    Cytotoxicity against human CFPAC-1 cells incubated for 24 hrs by MTT assay
    [PMID: 30904782]
    CHO IC50
    12 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against CHO cells by MTT assay
    Cytotoxicity against CHO cells by MTT assay
    [PMID: 29280630]
    CNE IC50
    15.07 μM
    Compound: 5-Fu
    Antiproliferative activity against human CNE cells assessed as inhibition of cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human CNE cells assessed as inhibition of cell viability after 48 hrs by MTT assay
    [PMID: 25113877]
    CNE IC50
    40.21 μM
    Compound: 5-FU
    Cytotoxicity against human CNE cells after 48 hrs by MTT assay
    Cytotoxicity against human CNE cells after 48 hrs by MTT assay
    [PMID: 24378217]
    CNE IC50
    45.1 μM
    Compound: 5-Fu
    Cytotoxicity against human CNE cells after 48 hrs by MTT assay
    Cytotoxicity against human CNE cells after 48 hrs by MTT assay
    [PMID: 24953029]
    CNE-2 IC50
    13.1 μM
    Compound: 5-FU
    Cytotoxicity against human CNE2 cells after 3 days by MTT assay
    Cytotoxicity against human CNE2 cells after 3 days by MTT assay
    [PMID: 21144621]
    CNE-2 IC50
    13.5 μM
    Compound: Fluorouracil
    Cytotoxicity against human CNE2 cells after 72 hrs ny MTT assay
    Cytotoxicity against human CNE2 cells after 72 hrs ny MTT assay
    [PMID: 22200404]
    CNE-2 IC50
    15.1 μM
    Compound: 5-FU
    Cytotoxicity against human CNE2 cells after 72 hrs by MTT assay
    Cytotoxicity against human CNE2 cells after 72 hrs by MTT assay
    [PMID: 22749192]
    CNE-2 IC50
    17.2 μM
    Compound: 5-FU
    Antiproliferative activity against human CNE2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human CNE2 cells after 72 hrs by MTT assay
    [PMID: 22079378]
    COLO 205 CC50
    > 2512 μM
    Compound: 5-Fu
    Cytotoxicity against human COLO205 cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human COLO205 cells after 48 hrs by sulforhodamine B assay
    [PMID: 26727215]
    COLO 205 GI50
    0.15 μM
    Compound: 5-FU
    Anticancer activity against human COLO 205 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human COLO 205 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    COLO 205 GI50
    0.15 μM
    Compound: 5-FU
    Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    COLO 205 IC50
    1.8 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human COLO205 cells assessed as cell growth inhibition by MTT assay
    Cytotoxicity against human COLO205 cells assessed as cell growth inhibition by MTT assay
    [PMID: 26629861]
    COLO 205 IC50
    1.9 μM
    Compound: 5-F
    Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay
    Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay
    [PMID: 28254697]
    COLO 205 IC50
    1.9 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human COLO205 cells by MTT assay
    Antiproliferative activity against human COLO205 cells by MTT assay
    [PMID: 29798826]
    COLO 205 IC50
    11.63 μM
    Compound: 5-FU
    Antiproliferative activity against p53 deficient human COLO205 cells after 72 hrs
    Antiproliferative activity against p53 deficient human COLO205 cells after 72 hrs
    [PMID: 18469809]
    COLO 205 IC50
    14.8 μM
    Compound: 5-Fu
    Cytotoxicity against human COLO205 cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human COLO205 cells after 48 hrs by sulforhodamine B assay
    [PMID: 26727215]
    COLO 205 GI50
    2.8 μM
    Compound: 5FU
    Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay
    [PMID: 21489802]
    COLO 205 IC50
    2.9 μM
    Compound: 5-Fu
    Cytotoxicity against Homo sapiens (human) COLO205 cells by SRB assay
    Cytotoxicity against Homo sapiens (human) COLO205 cells by SRB assay
    10.1007/s00044-010-9500-5
    COLO 205 IC50
    21 μM
    Compound: 5-FU
    Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay
    [PMID: 19939522]
    COLO 205 IC50
    27.7 μM
    Compound: 5-FU
    Cytotoxicity against human COLO 205 cells assessed as inhibition of cell growth incubated for 30 mins by SRB assay
    Cytotoxicity against human COLO 205 cells assessed as inhibition of cell growth incubated for 30 mins by SRB assay
    [PMID: 30114660]
    COLO 205 IC50
    3.39 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human COLO205 cells assessed as inhibition of tumor growth after 24 hrs
    Cytotoxicity against human COLO205 cells assessed as inhibition of tumor growth after 24 hrs
    [PMID: 24657568]
    COLO 205 EC50
    38.06 μM
    Compound: 5-FU
    Antiproliferative activity against human COLO205 cells after 24 hrs by MTT assay
    Antiproliferative activity against human COLO205 cells after 24 hrs by MTT assay
    [PMID: 25198997]
    COLO 205 IC50
    4.03 μg/mL
    Compound: 5-Fluorouracil
    Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay
    Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay
    [PMID: 23352638]
    COLO 205 IC50
    4.562 μg/mL
    Compound: 5-FU
    Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay
    Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay
    [PMID: 23548704]
    COLO 205 IC50
    5.29 μM
    Compound: 5-FU
    Cytotoxicity against human COLO 205 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    Cytotoxicity against human COLO 205 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    [PMID: 34170142]
    COLO 205 IC50
    90 μM
    Compound: 5-FU
    Antiproliferative activity against human p53 deficient COLO205 cells after 72 hrs by celltiter-glo assay
    Antiproliferative activity against human p53 deficient COLO205 cells after 72 hrs by celltiter-glo assay
    [PMID: 20873740]
    COLO 320 IC50
    10 μM
    Compound: 5-FU
    Antiproliferative activity against human COLO320 cells after 48 hrs
    Antiproliferative activity against human COLO320 cells after 48 hrs
    [PMID: 21458113]
    COLO 320 IC50
    12.5 μM
    Compound: 5-FU
    Cytotoxicity against human COLO320 cells assessed as cell viability after 72 hrs by WST-1 assay
    Cytotoxicity against human COLO320 cells assessed as cell viability after 72 hrs by WST-1 assay
    [PMID: 22955095]
    COLO 320 IC50
    8.7 μM
    Compound: 5-FU
    Antiproliferative activity against human COLO320 cells after 72 hrs
    Antiproliferative activity against human COLO320 cells after 72 hrs
    [PMID: 21458113]
    COLO 320DM IC50
    2 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human COLO320DM cells after 48 hrs by MTT assay
    Cytotoxicity against human COLO320DM cells after 48 hrs by MTT assay
    [PMID: 23792352]
    COLO357 IC50
    2.05 μM
    Compound: 5-FU
    Cytotoxicity against human Colo-357 cells by crystal violet staining
    Cytotoxicity against human Colo-357 cells by crystal violet staining
    [PMID: 20930123]
    Colon 26 IC50
    3.87 μM
    Compound: 5-Fluorouracil
    Dark toxicity against human Colon 26 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
    Dark toxicity against human Colon 26 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
    [PMID: 36561065]
    Colon 26 IC50
    4.1 μM
    Compound: 5-Fluorouracil
    Phototoxicity against human Colon 26 cells assessed as inhibition of cell growth preincubated for 24 hrs followed by compound washout with replacement of fresh medium and irradiation with 50 W LED light by MTT assay
    Phototoxicity against human Colon 26 cells assessed as inhibition of cell growth preincubated for 24 hrs followed by compound washout with replacement of fresh medium and irradiation with 50 W LED light by MTT assay
    [PMID: 36561065]
    COS-1 IC50
    110 μM
    Compound: 5-FU
    Cytotoxicity against african green monkey COS1 cells after 24 hrs by MTT assay
    Cytotoxicity against african green monkey COS1 cells after 24 hrs by MTT assay
    [PMID: 23202484]
    CT26.WT IC50
    5 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against mouse CT26.WT cells by MTT assay
    Cytotoxicity against mouse CT26.WT cells by MTT assay
    [PMID: 29280630]
    CWR22R IC50
    18.31 μM
    Compound: 5-FU
    Antiproliferative activity against human 22Rv1 cells assessed as cell growth inhibition by MTT assay
    Antiproliferative activity against human 22Rv1 cells assessed as cell growth inhibition by MTT assay
    [PMID: 34000484]
    CWR22R IC50
    3.83 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human 22Rv1 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
    Antiproliferative activity against human 22Rv1 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
    [PMID: 27295506]
    DAN-G IC50
    4.38 μM
    Compound: 5-FU
    Cytotoxicity against human DAN-G cells by crystal violet staining
    Cytotoxicity against human DAN-G cells by crystal violet staining
    [PMID: 20930123]
    DLD-1 IC50
    11.4 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human DLD-1 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay
    Antiproliferative activity against human DLD-1 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay
    [PMID: 32387836]
    DLD-1 EC50
    16.3 μM
    Compound: 5-FU
    Antiproliferative activity against human DLD1 cells after 24 hrs by MTT assay
    Antiproliferative activity against human DLD1 cells after 24 hrs by MTT assay
    [PMID: 25198997]
    DLD-1 IC50
    29.14 μM
    Compound: 5-Fu
    Cytotoxicity against human DLD1 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay
    Cytotoxicity against human DLD1 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay
    [PMID: 24583355]
    DLD-1 IC50
    33 μM
    Compound: 5-FU
    Antiproliferative activity against human DLD1 cells after 72 hrs by MTT assay
    Antiproliferative activity against human DLD1 cells after 72 hrs by MTT assay
    [PMID: 30429977]
    DLD-1 IC50
    33 μM
    Compound: 5-FU
    Antiproliferative activity against human DLD1 cells after 72 hrs by MTT assay
    Antiproliferative activity against human DLD1 cells after 72 hrs by MTT assay
    [PMID: 30037494]
    DLD-1 IC50
    7.38 μM
    Compound: 5-FU
    Cytotoxicity against human DLD1 cells after 96 hrs by MTT assay
    Cytotoxicity against human DLD1 cells after 96 hrs by MTT assay
    [PMID: 15387639]
    DMS-114 GI50
    100 μM
    Compound: 5-Fu
    Growth inhibition of human DMS114 cells after 48 hrs by SRB assay
    Growth inhibition of human DMS114 cells after 48 hrs by SRB assay
    [PMID: 22512908]
    DU-145 IC50
    > 100 μM
    Compound: 5-fluorouracil
    Cytotoxicity in human DU145 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity in human DU145 cells assessed as cell viability after 48 hrs by MTT assay
    [PMID: 21250700]
    DU-145 IC50
    > 100 μM
    Compound: 5-FU
    Cytotoxicity against human DU145 cells by MTT assay
    Cytotoxicity against human DU145 cells by MTT assay
    [PMID: 21689869]
    DU-145 GI50
    0.36 μM
    Compound: 5-FU
    Anticancer activity against human DU-145 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human DU-145 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    DU-145 GI50
    0.36 μM
    Compound: 5-FU
    Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    DU-145 GI50
    1 μg/mL
    Compound: 5FU
    Cytotoxicity against human DU145 cells assessed as growth inhibition after 48 hrs by SRB assay method
    Cytotoxicity against human DU145 cells assessed as growth inhibition after 48 hrs by SRB assay method
    [PMID: 26383125]
    DU-145 IC50
    1.3 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human DU145 cells after 24 hrs by MTT assay
    Cytotoxicity against human DU145 cells after 24 hrs by MTT assay
    [PMID: 24060486]
    DU-145 IC50
    1.5 μM
    Compound: 5-FU
    Cytotoxicity against human DU145 cells after 24 hrs by MTT assay
    Cytotoxicity against human DU145 cells after 24 hrs by MTT assay
    [PMID: 24835633]
    DU-145 IC50
    1.6 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human DU145 cells assessed as cell growth inhibition by MTT assay
    Cytotoxicity against human DU145 cells assessed as cell growth inhibition by MTT assay
    [PMID: 27561719]
    DU-145 IC50
    1.7 μM
    Compound: 5-FU
    Cytotoxicity against human DU145 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    Cytotoxicity against human DU145 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    [PMID: 27528432]
    DU-145 IC50
    1.9 μM
    Compound: 5-Fluoro uracilc
    Cytotoxicity against human DU145 cells assessed as growth inhibition after 24 hrs by MTT assay
    Cytotoxicity against human DU145 cells assessed as growth inhibition after 24 hrs by MTT assay
    [PMID: 24641975]
    DU-145 IC50
    11.9 μM
    Compound: 5-FU
    Antiproliferative activity against prostate cancer DU-145 cell line using sulforhodamine B(SRB) assay
    Antiproliferative activity against prostate cancer DU-145 cell line using sulforhodamine B(SRB) assay
    [PMID: 15801848]
    DU-145 IC50
    11.9 μM
    Compound: 5-FU
    Antiproliferative activity against human prostate cancer DU-145 cell line by sulforhodamine B assay
    Antiproliferative activity against human prostate cancer DU-145 cell line by sulforhodamine B assay
    [PMID: 16005217]
    DU-145 IC50
    11.9 μM
    Compound: 5-FU
    Antiproliferative activity was evaluated against human prostate DU-145 cancer cell lines using the sulforhodamine B (STB) assay
    Antiproliferative activity was evaluated against human prostate DU-145 cancer cell lines using the sulforhodamine B (STB) assay
    [PMID: 15454213]
    DU-145 IC50
    12.32 μM
    Compound: 5-Fu
    Cytotoxicity against human DU145 cells after 72 hrs by MTT assay
    Cytotoxicity against human DU145 cells after 72 hrs by MTT assay
    [PMID: 22687745]
    DU-145 GI50
    15.4 μM
    Compound: 5FU
    Cytotoxicity against human DU145 cells after 48 hrs
    Cytotoxicity against human DU145 cells after 48 hrs
    [PMID: 18798609]
    DU-145 IC50
    2.18 μM
    Compound: 5-FU
    Cytotoxicity in human DU145 cells incubated for 48 hrs by MTT assay
    Cytotoxicity in human DU145 cells incubated for 48 hrs by MTT assay
    [PMID: 28923381]
    DU-145 IC50
    2.18 μM
    Compound: 5-FU
    Cytotoxicity against human DU145 cells after 48 hrs by MTT assay
    Cytotoxicity against human DU145 cells after 48 hrs by MTT assay
    [PMID: 28431881]
    DU-145 IC50
    2.19 μM
    Compound: 5-FU
    Cytotoxicity against human DU145 cells after 72 hrs by MTT assay
    Cytotoxicity against human DU145 cells after 72 hrs by MTT assay
    [PMID: 20494492]
    DU-145 IC50
    2.5 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human DU145 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human DU145 cells incubated for 72 hrs by MTT assay
    [PMID: 31829592]
    DU-145 IC50
    2.95 μM
    Compound: 5-FU
    Antitumor activity against Homo sapiens (human) DU145 cells assessed as inhibition of cell viability after 72 hr by MTT assay
    Antitumor activity against Homo sapiens (human) DU145 cells assessed as inhibition of cell viability after 72 hr by MTT assay
    10.1007/s00044-012-0283-8
    DU-145 IC50
    2.95 μM
    Compound: 5-FU
    Cytotoxicity against Homo sapiens (human) DU145 cells by MTT assay
    Cytotoxicity against Homo sapiens (human) DU145 cells by MTT assay
    10.1007/s00044-010-9395-1
    DU-145 GI50
    20 nM
    Compound: 5FU
    Growth inhibition of human DU145 cells after 48 hrs by SRB assay
    Growth inhibition of human DU145 cells after 48 hrs by SRB assay
    [PMID: 23094992]
    DU-145 IC50
    24.2 μM
    Compound: 5 Fluorouracil
    Cytotoxicity against human DU145 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human DU145 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    [PMID: 27496212]
    DU-145 IC50
    25.3 μM
    Compound: 5-Fu
    Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay
    Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay
    [PMID: 30527868]
    DU-145 IC50
    26.1 μM
    Compound: 5-Fu
    Cytotoxicity against human DU145 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human DU145 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 27561718]
    DU-145 IC50
    38 μM
    Compound: 5-Fu
    Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay
    Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay
    10.1039/C5MD00382B
    DU-145 IC50
    39.17 μM
    Compound: 5-FU
    Cytotoxicity in human DU145 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity in human DU145 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 29657100]
    DU-145 IC50
    39.17 μM
    Compound: 5-FU
    Cytotoxicity against human DU145 cells after 48 hrs by MTT assay
    Cytotoxicity against human DU145 cells after 48 hrs by MTT assay
    [PMID: 27397498]
    DU-145 IC50
    39.17 μM
    Compound: 5-FU
    Anticancer activity against human DU145 cells after 48 hrs by MTT assay
    Anticancer activity against human DU145 cells after 48 hrs by MTT assay
    [PMID: 26413726]
    DU-145 IC50
    4.8 μM
    Compound: 5-fluorouracil
    Anticancer activity against human DU145 cells assessed as cell viability after 48 hrs by SRB assay
    Anticancer activity against human DU145 cells assessed as cell viability after 48 hrs by SRB assay
    [PMID: 21074444]
    DU-145 IC50
    40.58 μM
    Compound: 5-FU
    Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 27614408]
    DU-145 GI50
    5.82 μM
    Compound: 5-FU
    Growth inhibition of human DU145 cells after 48 hrs by SRB assay
    Growth inhibition of human DU145 cells after 48 hrs by SRB assay
    [PMID: 28400235]
    DU-145 IC50
    6.072 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay
    Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay
    [PMID: 26301558]
    DU-145 IC50
    6.37 μM
    Compound: 5-FU
    Cytotoxicity against human DU145 cells after 48 hrs by MTT assay
    Cytotoxicity against human DU145 cells after 48 hrs by MTT assay
    [PMID: 25870131]
    DU-145 GI50
    9.37 μM
    Compound: 5-Fu
    Growth inhibition of human DU145 cells after 48 hrs by SRB assay
    Growth inhibition of human DU145 cells after 48 hrs by SRB assay
    [PMID: 22512908]
    E0771 IC50
    0.28 μM
    Compound: 5-Fu
    Cytotoxicity against mouse E0771 cells after 3 days by SRB assay
    Cytotoxicity against mouse E0771 cells after 3 days by SRB assay
    [PMID: 24704691]
    EC9706 IC50
    0.32 μM
    Compound: 5-Fu
    Cytotoxicity against human EC9706 cells after 72 hrs by MTT assay
    Cytotoxicity against human EC9706 cells after 72 hrs by MTT assay
    [PMID: 23644193]
    EC9706 IC50
    15.67 μM
    Compound: 5-Fu
    Cytotoxicity against human EC9706 cells after 72 hrs by MTT assay
    Cytotoxicity against human EC9706 cells after 72 hrs by MTT assay
    [PMID: 25707012]
    EC9706 IC50
    20.3 μM
    Compound: 5-Fu
    Antitumor activity against human EC9706 cells after 72 hrs by MTT assay
    Antitumor activity against human EC9706 cells after 72 hrs by MTT assay
    [PMID: 21486694]
    EC9706 IC50
    23.26 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human EC9706 cells after 48 hrs by MTT assay
    Antiproliferative activity against human EC9706 cells after 48 hrs by MTT assay
    [PMID: 28119200]
    EC9706 IC50
    4.7 μM
    Compound: 5-Fu
    Anticancer activity against human EC9706 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    Anticancer activity against human EC9706 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    [PMID: 25086915]
    EC9706 IC50
    5.13 μM
    Compound: 5-Fu
    Antiproliferative activity against human EC9706 cells after 72 hrs by MTT assay
    Antiproliferative activity against human EC9706 cells after 72 hrs by MTT assay
    [PMID: 29475156]
    EC9706 IC50
    8.07 μM
    Compound: 5-Fu
    Anticancer activity against human EC9706 cells after 72 hrs by MTT assay
    Anticancer activity against human EC9706 cells after 72 hrs by MTT assay
    [PMID: 25001482]
    EC9706 IC50
    9.45 μM
    Compound: 5-Fu
    Antiproliferative activity against human EC9706 cells after 48 hrs by MTT assay
    Antiproliferative activity against human EC9706 cells after 48 hrs by MTT assay
    [PMID: 24835817]
    ECa-109 cell line IC50
    10.3 μM
    Compound: 5-FU
    Cytotoxicity against human EC109 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
    Cytotoxicity against human EC109 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
    [PMID: 28038329]
    ECa-109 cell line IC50
    10.3 μM
    Compound: 5-FU
    Cytotoxicity against human EC109 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human EC109 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    [PMID: 27423479]
    ECa-109 cell line IC50
    10.59 μM
    Compound: 5-Fu
    Antiproliferative activity against human EC109 cells after 72 hrs by MTT assay
    Antiproliferative activity against human EC109 cells after 72 hrs by MTT assay
    [PMID: 27771599]
    ECa-109 cell line IC50
    10.61 μM
    Compound: 5-Fu
    Cytotoxicity against human EC109 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human EC109 cells assessed as growth inhibition after 72 hrs by MTT assay
    [PMID: 24077182]
    ECa-109 cell line IC50
    10.61 μM
    Compound: 5-Fu
    Cytotoxicity against human EC109 cells after 72 hrs by MTT assay
    Cytotoxicity against human EC109 cells after 72 hrs by MTT assay
    [PMID: 23792764]
    ECa-109 cell line IC50
    10.81 μM
    Compound: 5-Fu
    Cytotoxicity against human EC109 cells assessed as inhibition of proliferation after 72 hrs by MTT assay
    Cytotoxicity against human EC109 cells assessed as inhibition of proliferation after 72 hrs by MTT assay
    [PMID: 25180925]
    ECa-109 cell line IC50
    11.1 μM
    Compound: 5-Fu
    Antiproliferative activity against human EC109 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
    Antiproliferative activity against human EC109 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
    [PMID: 34455358]
    ECa-109 cell line IC50
    11.37 μM
    Compound: 5-FU
    Antiproliferative activity against human EC109 cells assessed as inhibition of cell growth by SRB assay
    Antiproliferative activity against human EC109 cells assessed as inhibition of cell growth by SRB assay
    [PMID: 35594653]
    ECa-109 cell line IC50
    11.61 μM
    Compound: 5-Fu
    Anticancer activity against human EC109 cells assessed as inhibition of proliferation after 72 hrs by MTT assay
    Anticancer activity against human EC109 cells assessed as inhibition of proliferation after 72 hrs by MTT assay
    [PMID: 25655718]
    ECa-109 cell line IC50
    15.9 μM
    Compound: 5-Fu
    Cytotoxicity against human EC109 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human EC109 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    10.1039/C5MD00240K
    ECa-109 cell line IC50
    21.21 μM
    Compound: 5-FU
    Antiproliferative activity against human EC109 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
    Antiproliferative activity against human EC109 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
    [PMID: 31740251]
    ECa-109 cell line IC50
    24.14 μM
    Compound: 5-Fu
    Cytotoxicity against human EC109 cells after 72 hrs by MTT assay
    Cytotoxicity against human EC109 cells after 72 hrs by MTT assay
    [PMID: 24798098]
    ECa-109 cell line IC50
    25.99 μM
    Compound: 5-FU
    Cytotoxicity against human EC109 cells assessed as growth inhibition by MTT assay
    Cytotoxicity against human EC109 cells assessed as growth inhibition by MTT assay
    [PMID: 27769034]
    ECa-109 cell line IC50
    3.17 μM
    Compound: 5-Fu
    Antiproliferative activity against human EC109 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Antiproliferative activity against human EC109 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    [PMID: 27105028]
    ECa-109 cell line IC50
    3.34 μM
    Compound: 5-Fu
    Cytotoxicity against human EC109 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human EC109 cells assessed as growth inhibition after 72 hrs by MTT assay
    [PMID: 23353743]
    ECa-109 cell line IC50
    30.25 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human ECA109 cells after 48 hrs by MTT assay
    Antiproliferative activity against human ECA109 cells after 48 hrs by MTT assay
    [PMID: 28119200]
    ECa-109 cell line IC50
    5.01 μM
    Compound: 5-FU
    Antiproliferative activity against human EC109 cells after 72 hrs by MTT assay
    Antiproliferative activity against human EC109 cells after 72 hrs by MTT assay
    [PMID: 28759876]
    ECa-109 cell line IC50
    56.2 μM
    Compound: 5-FU
    Antiproliferative activity against human EC109 cells after 48 hrs by MTT assay
    Antiproliferative activity against human EC109 cells after 48 hrs by MTT assay
    [PMID: 28763643]
    ECa-109 cell line IC50
    6.02 μM
    Compound: 5-Fu
    Antiproliferative activity against human EC109 cells after 72 hrs by MTT assay
    Antiproliferative activity against human EC109 cells after 72 hrs by MTT assay
    [PMID: 29475156]
    ECa-109 cell line IC50
    6.21 μM
    Compound: 5-Fu
    Antiproliferative activity against human EC109 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human EC109 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    [PMID: 29113745]
    ECa-109 cell line IC50
    6.21 μM
    Compound: 5-FU
    Antiproliferative activity against human EC109 cells after 48 hrs by MTT assay
    Antiproliferative activity against human EC109 cells after 48 hrs by MTT assay
    [PMID: 28863355]
    ECa-109 cell line IC50
    6.21 μM
    Compound: 5-FU
    Antiproliferative activity against human EC109 cells after 48 hrs by MTT assay
    Antiproliferative activity against human EC109 cells after 48 hrs by MTT assay
    [PMID: 28838695]
    ECa-109 cell line IC50
    6.5 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human EC109 cells by MTT assay
    Antiproliferative activity against human EC109 cells by MTT assay
    [PMID: 31546197]
    Ehrlich IC50
    0.38 μM
    Compound: 5-FU
    Antitumor activity against mouse EAC cells by trypan blue exclusion assay
    Antitumor activity against mouse EAC cells by trypan blue exclusion assay
    10.1007/s00044-013-0859-y
    Ehrlich IC50
    1.5 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against mouse EAC cells assessed as cell viability using trypan blue staining after 2 hrs by hemocytometer analysis
    Cytotoxicity against mouse EAC cells assessed as cell viability using trypan blue staining after 2 hrs by hemocytometer analysis
    [PMID: 21353349]
    Ehrlich IC50
    14.3 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against mouse EAC cells after 48 hrs by MTT assay
    Cytotoxicity against mouse EAC cells after 48 hrs by MTT assay
    [PMID: 24534537]
    Ehrlich IC50
    14.6 μM
    Compound: 5-fluorouracil
    Cytotoxicity against mouse EAC cells after 48 hrs by trypan blue dye exclusion method
    Cytotoxicity against mouse EAC cells after 48 hrs by trypan blue dye exclusion method
    [PMID: 25261825]
    Ehrlich IC50
    15.4 μM
    Compound: 5-fluorouracil
    Cytotoxicity against mouse EAC cells after 48 hrs by LDH release assay
    Cytotoxicity against mouse EAC cells after 48 hrs by LDH release assay
    [PMID: 25261825]
    Ehrlich IC50
    16.3 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against mouse EAC cells after 48 hrs by LDH release assay
    Cytotoxicity against mouse EAC cells after 48 hrs by LDH release assay
    [PMID: 24534537]
    Ehrlich IC50
    16.3 μM
    Compound: 5-fluorouracil
    Cytotoxicity against mouse EAC cells after 48 hrs by MTT method
    Cytotoxicity against mouse EAC cells after 48 hrs by MTT method
    [PMID: 25261825]
    Ehrlich IC50
    16.4 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against mouse EAC cells after 48 hrs by trypan blue exclusion assay
    Cytotoxicity against mouse EAC cells after 48 hrs by trypan blue exclusion assay
    [PMID: 24534537]
    Ehrlich CC50
    37.36 μM
    Compound: 5-FU
    Cytotoxicity against mouse EAC cell assessed as reduction in cell viability incubated for 3 hrs by tryphan blue dye based assay
    Cytotoxicity against mouse EAC cell assessed as reduction in cell viability incubated for 3 hrs by tryphan blue dye based assay
    [PMID: 33540356]
    Ehrlich ED50
    38.6 ug
    Compound: 5-FU
    Cytotoxicity against mouse EAC after 2 hrs by trypan blue staining based hemocytometer analysis
    Cytotoxicity against mouse EAC after 2 hrs by trypan blue staining based hemocytometer analysis
    [PMID: 23022735]
    Ehrlich ED50
    58 uL
    Compound: 5FU
    Antitumor activity against mouse EAC cells tansplanted in Swiss albino mouse assessed as dead cells at 50 to 250 mg/kg/day, ip by tyrpan blue assay
    Antitumor activity against mouse EAC cells tansplanted in Swiss albino mouse assessed as dead cells at 50 to 250 mg/kg/day, ip by tyrpan blue assay
    [PMID: 19527933]
    Ehrlich ED50
    63 μg/cm3
    Compound: 5-FU
    In vitro antitumor activity against Mus musculus (mouse) Ehrlich ascites cell assessed as dead tumor cells by trypan blue exclusion test
    In vitro antitumor activity against Mus musculus (mouse) Ehrlich ascites cell assessed as dead tumor cells by trypan blue exclusion test
    10.1007/s00044-012-0336-z
    Ehrlich IC50
    9.2 μM
    Compound: 5-fluorouracil
    Cytotoxicity against mouse EAC cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against mouse EAC cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 29133037]
    Ehrlich IC50
    9.6 μM
    Compound: 5-fluorouracil
    Cytotoxicity against mouse EAC cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay
    Cytotoxicity against mouse EAC cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay
    [PMID: 29133037]
    Ehrlich CC50
    90.55 μM
    Compound: 5-FU
    Growth inhibition of EAC cells after 3 hrs
    Growth inhibition of EAC cells after 3 hrs
    [PMID: 17239491]
    Ehrlich ED50
    96.3 mM
    Compound: 5-flu
    Cytotoxicity against Mus musculus (mouse) EAC assessed as cell viability by trypan blue exclusion assay
    Cytotoxicity against Mus musculus (mouse) EAC assessed as cell viability by trypan blue exclusion assay
    10.1007/s00044-009-9199-3
    Ehrlich IC50
    97.3 ug
    Compound: 5-FU
    Cytotoxicity against mouse EAC after 2 hrs by trypan blue staining based hemocytometer analysis
    Cytotoxicity against mouse EAC after 2 hrs by trypan blue staining based hemocytometer analysis
    [PMID: 23022735]
    EKVX GI50
    61.8 μM
    Compound: 5-FU
    Growth inhibition of human EKVX cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human EKVX cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    Fibroblast IC50
    > 50 μM
    Compound: 5-FU
    Cytotoxicity against human skin fibroblast cells incubated for 72 hrs by MTT assay
    Cytotoxicity against human skin fibroblast cells incubated for 72 hrs by MTT assay
    [PMID: 35367708]
    Fibroblast IC50
    11 μM
    Compound: 5-FU
    Antiproliferative activity against human fibroblasts after 48 hrs by resazurin reduction test
    Antiproliferative activity against human fibroblasts after 48 hrs by resazurin reduction test
    [PMID: 21530016]
    FM3A IC50
    0.18 μM
    Compound: 5-FU
    Cytostatic activity against mouse FM3A cells after 2 days by coulter counting analysis
    Cytostatic activity against mouse FM3A cells after 2 days by coulter counting analysis
    [PMID: 21330014]
    GES1 IC50
    > 100 μM
    Compound: 5-Fu
    Cytotoxicity against human GES1 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    Cytotoxicity against human GES1 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    [PMID: 35191714]
    GES1 IC50
    10.21 μM
    Compound: 5-FU
    Cytotoxicity against human GES1 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human GES1 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    [PMID: 31577977]
    GES1 IC50
    12.51 μM
    Compound: 5-Fu
    Cytotoxicity against human GES-1 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    Cytotoxicity against human GES-1 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    [PMID: 30388465]
    GES1 IC50
    12.51 μM
    Compound: 5-Fu
    Antiproliferative activity against human GES-1 cells after 72 hrs by MTT assay
    Antiproliferative activity against human GES-1 cells after 72 hrs by MTT assay
    [PMID: 29635165]
    GES1 IC50
    13.75 μM
    Compound: 5-FU
    Cytotoxicity against human GES-1 cells assessed as growth inhibition after 72 hrs by CCK8 assay
    Cytotoxicity against human GES-1 cells assessed as growth inhibition after 72 hrs by CCK8 assay
    [PMID: 27597411]
    GES1 IC50
    19.27 μM
    Compound: 5-FU
    Cytotoxicity against human GES1 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Cytotoxicity against human GES1 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    [PMID: 34302974]
    GES1 IC50
    2.37 μM
    Compound: 5-Fu
    Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    [PMID: 32682202]
    GES1 IC50
    2.45 μM
    Compound: 5-Fu
    Antiproliferative activity against human GES1 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Antiproliferative activity against human GES1 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    [PMID: 33385852]
    GES1 IC50
    3.69 μM
    Compound: 5-FU
    Antiproliferative activity against human GES-1 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human GES-1 cells incubated for 72 hrs by MTT assay
    [PMID: 31404863]
    GES1 IC50
    30.9 μM
    Compound: 5-Fu
    Cytotoxicity against human GES-1 cells after 48 hrs by MTT assay
    Cytotoxicity against human GES-1 cells after 48 hrs by MTT assay
    [PMID: 25462264]
    GES1 IC50
    38.5 μM
    Compound: 5-Fu
    Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    [PMID: 34628244]
    GES1 IC50
    49.6 μM
    Compound: 5-FU
    Antiproliferative activity against human GES1 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Antiproliferative activity against human GES1 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    [PMID: 35286954]
    GES1 IC50
    7.22 μM
    Compound: 5-Fu
    Cytotoxicity against human GES-1 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human GES-1 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    10.1039/C6MD00169F
    GES1 IC50
    78.4 μM
    Compound: 5-FU
    Toxicity in human GES1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Toxicity in human GES1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 35085721]
    GES1 IC50
    8.59 μM
    Compound: 5-FU
    Cytotoxicity against human GES-1 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human GES-1 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 28759876]
    GES1 IC50
    9.02 μM
    Compound: 5-FU
    Antiproliferative activity against human GES-1 cells after 48 hrs by MTT assay
    Antiproliferative activity against human GES-1 cells after 48 hrs by MTT assay
    [PMID: 28863355]
    GTL 16 cell line IC50
    0.84 μM
    Compound: 5-FU
    Antitumor activity against human GTL 16 cell line assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay
    Antitumor activity against human GTL 16 cell line assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay
    [PMID: 36324491]
    H4 CC50
    3843.8 μM
    Compound: 5-Fu
    Cytotoxicity against human H4 cells after 72 hrs
    Cytotoxicity against human H4 cells after 72 hrs
    [PMID: 18037195]
    H4 CC50
    3843.8 μM
    Compound: 5FU
    Cytotoxicity against human H4 cells after 72 hrs
    Cytotoxicity against human H4 cells after 72 hrs
    [PMID: 17555969]
    H4 CC50
    3843.8 μM
    Compound: 5FU
    Cytotoxicity against human H4 cells after 72 hrs
    Cytotoxicity against human H4 cells after 72 hrs
    [PMID: 17548129]
    H4 CC50
    3843.8 μM
    Compound: 5-FU
    Cytotoxicity against human H4 cells after 72 hrs
    Cytotoxicity against human H4 cells after 72 hrs
    [PMID: 17337193]
    H69AR GI50
    100 μM
    Compound: 5-Fu
    Growth inhibition of human H69AR cells after 48 hrs by SRB assay
    Growth inhibition of human H69AR cells after 48 hrs by SRB assay
    [PMID: 22512908]
    HaCaT IC50
    0.3 μM
    Compound: 5-Fluorouracil
    Cytostatic activity against human HaCaT cells after 72 hrs by MTT assay
    Cytostatic activity against human HaCaT cells after 72 hrs by MTT assay
    [PMID: 22405290]
    HaCaT IC50
    0.4 μM
    Compound: 5-FU
    Growth inhibition of human HaCaT cells after 72 hrs by MTT assay
    Growth inhibition of human HaCaT cells after 72 hrs by MTT assay
    [PMID: 18640746]
    HaCaT IC50
    15.26 μM
    Compound: 5-Fluorouracil
    Cytotoxic activity against human HaCaT cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay
    Cytotoxic activity against human HaCaT cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay
    [PMID: 26231080]
    HaCaT IC50
    16.15 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HaCaT cells after 48 hrs by MTT assay
    Antiproliferative activity against human HaCaT cells after 48 hrs by MTT assay
    [PMID: 27092413]
    HBL-100 IC50
    4.3 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HBL100 cells by MTT assay
    Antiproliferative activity against human HBL100 cells by MTT assay
    [PMID: 31546197]
    HBL-100 GI50
    5.5 μM
    Compound: 5-FU
    Antiproliferative activity against human HBL100 cells assessed as growth inhibition after 48 hrs by SRB assay
    Antiproliferative activity against human HBL100 cells assessed as growth inhibition after 48 hrs by SRB assay
    [PMID: 31376562]
    HBL-100 GI50
    5.5 μM
    Compound: 5-FU
    Antiproliferative activity against human HBL100 cells after 48 hrs by SRB assay
    Antiproliferative activity against human HBL100 cells after 48 hrs by SRB assay
    [PMID: 28728108]
    HBL-100 GI50
    5.5 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HBL100 cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human HBL100 cells after 48 hrs by sulforhodamine B assay
    [PMID: 25752525]
    HBL-100 GI50
    5.5 μM
    Compound: 5-FU
    Growth inhibition of human HBL100 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human HBL100 cells after 48 hrs by sulforhodamine B assay
    [PMID: 19664930]
    HCC 2998 CC50
    > 2512 μM
    Compound: 5-Fu
    Cytotoxicity against human HCC2998 cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human HCC2998 cells after 48 hrs by sulforhodamine B assay
    [PMID: 26727215]
    HCC 2998 GI50
    0.05 μM
    Compound: 5-FU
    Anticancer activity against human HCC 2998 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human HCC 2998 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    HCC 2998 GI50
    0.05 μM
    Compound: 5-FU
    Growth inhibition of human HCC2998 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human HCC2998 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    HCC 2998 IC50
    12.6 μM
    Compound: 5-FU
    Cytotoxicity against human HCC 2998 cells assessed as inhibition of cell viability incubated for 72 hrs under hypoxia condition by MTT assay
    Cytotoxicity against human HCC 2998 cells assessed as inhibition of cell viability incubated for 72 hrs under hypoxia condition by MTT assay
    [PMID: 35182815]
    HCC 2998 IC50
    14.8 μM
    Compound: 5-Fu
    Cytotoxicity against human HCC2998 cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human HCC2998 cells after 48 hrs by sulforhodamine B assay
    [PMID: 26727215]
    HCC 2998 IC50
    5.75 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HCC2998 cells assessed as inhibition of tumor growth after 24 hrs
    Cytotoxicity against human HCC2998 cells assessed as inhibition of tumor growth after 24 hrs
    [PMID: 24657568]
    HCC1937 IC50
    25.94 μM
    Compound: 5-FU
    Antitumor activity against human HCC1937 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay
    Antitumor activity against human HCC1937 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay
    [PMID: 36324491]
    HCCLM3 IC50
    1.84 mM
    Compound: 5-FU
    Antiproliferative activity against human HCCLM3 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay
    Antiproliferative activity against human HCCLM3 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay
    [PMID: 28073674]
    HCT-116 GI50
    > 10 μM
    Compound: 4; 5-FU
    Antiproliferative activity against human HCT-116 cells measured after 48 hrs by SRB assay
    Antiproliferative activity against human HCT-116 cells measured after 48 hrs by SRB assay
    [PMID: 32683166]
    HCT-116 EC50
    > 1000 μM
    Compound: 5-FU
    Antiproliferative activity against 5-FU resistant DPD expressed human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Antiproliferative activity against 5-FU resistant DPD expressed human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 34688013]
    HCT-116 EC50
    > 1000 μM
    Compound: 5-FU
    Reversal of 5-FU resistance against human HCT-116 cells overexpressing DPD assessed as inhibition of cell proliferation measured after 72 hrs in presence of 5-FU by MTT assay
    Reversal of 5-FU resistance against human HCT-116 cells overexpressing DPD assessed as inhibition of cell proliferation measured after 72 hrs in presence of 5-FU by MTT assay
    [PMID: 34411894]
    HCT-116 CC50
    > 2512 μM
    Compound: 5-Fu
    Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay
    [PMID: 26727215]
    HCT-116 IC50
    > 50 μM
    Compound: 5-FU
    Anticancer activity against human HCT116 cells assessed as inhibition of cell growth after 24 hrs by MTT assay
    Anticancer activity against human HCT116 cells assessed as inhibition of cell growth after 24 hrs by MTT assay
    [PMID: 26922233]
    HCT-116 EC50
    > 50 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT116 cells after 24 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 24 hrs by MTT assay
    [PMID: 25198997]
    HCT-116 IC50
    > 50 μM
    Compound: 5-FU
    Anticancer activity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
    Anticancer activity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
    [PMID: 26922233]
    HCT-116 IC50
    0.041 mM
    Compound: 5-Fluorouracil
    Cytotoxicity in human HCT116 cells assessed as reduction in cell viability by MTT assay
    Cytotoxicity in human HCT116 cells assessed as reduction in cell viability by MTT assay
    [PMID: 28334654]
    HCT-116 IC50
    0.0462 mM
    Compound: 5-FU
    Cytotoxicity against Homo sapiens (human) HCT116 cells assessed as growth inhibition after 72 hr by MTT assay
    Cytotoxicity against Homo sapiens (human) HCT116 cells assessed as growth inhibition after 72 hr by MTT assay
    10.1007/s00044-012-0181-0
    HCT-116 GI50
    0.22 μM
    Compound: 5-FU
    Anticancer activity against human HCT-116 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human HCT-116 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    HCT-116 GI50
    0.22 μM
    Compound: 5-FU
    Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    HCT-116 ED50
    0.48 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human HCT116 cells by MTT assay
    Cytotoxicity against human HCT116 cells by MTT assay
    [PMID: 11908984]
    HCT-116 IC50
    0.5 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay
    Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay
    [PMID: 25066282]
    HCT-116 EC50
    0.5 μM
    Compound: 1; 5-FU
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability measured after 5 days by PrestoBlue reagent based assay
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability measured after 5 days by PrestoBlue reagent based assay
    [PMID: 34979089]
    HCT-116 IC50
    0.54 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HCT116 cells assessed as reduction in cell viability by SRB assay
    Cytotoxicity against human HCT116 cells assessed as reduction in cell viability by SRB assay
    [PMID: 30660827]
    HCT-116 IC50
    1.7 μM
    Compound: 5-FU
    Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
    Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
    [PMID: 33321421]
    HCT-116 IC50
    1.93 μM
    Compound: 5-FU
    Antitumor activity against Homo sapiens (human) HCT116 cells assessed as inhibition of cell viability after 72 hr by MTT assay
    Antitumor activity against Homo sapiens (human) HCT116 cells assessed as inhibition of cell viability after 72 hr by MTT assay
    10.1007/s00044-012-0283-8
    HCT-116 IC50
    1.93 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
    Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
    [PMID: 20494492]
    HCT-116 IC50
    1.93 μM
    Compound: 5-FU
    Cytotoxicity against Homo sapiens (human) HCT116 cells by MTT assay
    Cytotoxicity against Homo sapiens (human) HCT116 cells by MTT assay
    10.1007/s00044-010-9395-1
    HCT-116 IC50
    10.05 μM
    Compound: 5-Fu
    Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
    [PMID: 24953029]
    HCT-116 IC50
    10.54 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    [PMID: 24819956]
    HCT-116 IC50
    10.81 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 33538581]
    HCT-116 IC50
    11.29 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    [PMID: 29316536]
    HCT-116 IC50
    11.56 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
    Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
    [PMID: 30318440]
    HCT-116 IC50
    12 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT116 cells expressing p53 after 72 hrs by celltiter-glo assay
    Antiproliferative activity against human HCT116 cells expressing p53 after 72 hrs by celltiter-glo assay
    [PMID: 20873740]
    HCT-116 IC50
    12.31 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay
    Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay
    [PMID: 32387836]
    HCT-116 IC50
    13 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HCT116 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells incubated for 72 hrs by MTT assay
    [PMID: 31829592]
    HCT-116 IC50
    13.8 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 32682200]
    HCT-116 IC50
    13.9 μM
    Compound: 1; 5-FU
    Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs in presence of 5 mM GSH by SRB assay
    Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs in presence of 5 mM GSH by SRB assay
    [PMID: 33819035]
    HCT-116 IC50
    14.8 μM
    Compound: 5-Fu
    Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay
    [PMID: 26727215]
    HCT-116 IC50
    14.9 μM
    Compound: 1; 5-FU
    Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
    Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
    [PMID: 33819035]
    HCT-116 IC50
    15.38 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 27448774]
    HCT-116 IC50
    15.52 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 30709651]
    HCT-116 IC50
    17.25 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    [PMID: 29486954]
    HCT-116 IC50
    18.4 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay
    Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay
    [PMID: 30108969]
    HCT-116 IC50
    18.4 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by SRB assay
    Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by SRB assay
    [PMID: 28219046]
    HCT-116 IC50
    18.7 μM
    Compound: 5FU
    Cytotoxicity against human HCT116 cells incubated for 72 hrs by SRB assay
    Cytotoxicity against human HCT116 cells incubated for 72 hrs by SRB assay
    [PMID: 22867707]
    HCT-116 IC50
    19.2 μM
    Compound: 5-FU
    Cytotoxicity against Homo sapiens (human) HCT116 cells assessed as growth inhibition after 48 hr by MTT assay
    Cytotoxicity against Homo sapiens (human) HCT116 cells assessed as growth inhibition after 48 hr by MTT assay
    10.1007/s00044-012-0461-8
    HCT-116 IC50
    19.2 μM
    Compound: 5-FU
    Anticancer activity against Homo sapiens (human) HCT116 cells assessed as inhibition of cell proliferation after 72 hr by MTT assay
    Anticancer activity against Homo sapiens (human) HCT116 cells assessed as inhibition of cell proliferation after 72 hr by MTT assay
    10.1007/s00044-012-0240-6
    HCT-116 IC50
    19.27 μM
    Compound: 5-Fu
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability by MTT assay
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability by MTT assay
    [PMID: 34715305]
    HCT-116 IC50
    2 mM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    [PMID: 27847140]
    HCT-116 IC50
    2.3 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
    [PMID: 26854375]
    HCT-116 IC50
    2.5 μM
    Compound: 5-FU
    Growth inhibition of human HCT116 cells after 72 hrs by MTS assay
    Growth inhibition of human HCT116 cells after 72 hrs by MTS assay
    [PMID: 27704811]
    HCT-116 IC50
    2.6 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    [PMID: 19743863]
    HCT-116 IC50
    2.8 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT116 cells after 72 hrs
    Antiproliferative activity against human HCT116 cells after 72 hrs
    [PMID: 17548198]
    HCT-116 IC50
    20.4 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
    [PMID: 31471102]
    HCT-116 IC50
    201 μg/mL
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    [PMID: 29207336]
    HCT-116 IC50
    21.54 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 36269639]
    HCT-116 IC50
    24.43 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
    [PMID: 24565905]
    HCT-116 IC50
    24.58 μM
    Compound: 5-FU
    Cytotoxic activity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
    Cytotoxic activity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
    [PMID: 26706349]
    HCT-116 IC50
    24.8 μM
    Compound: 5-Fu
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 30981113]
    HCT-116 IC50
    26.14 μM
    Compound: 5-Fu
    Anticancer activity against human HCT116 cells expressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay
    Anticancer activity against human HCT116 cells expressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 31509699]
    HCT-116 IC50
    26.2 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    [PMID: 28400238]
    HCT-116 IC50
    26042.5 nM
    Compound: 5-FU
    Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 32203786]
    HCT-116 IC50
    27.76 μM
    Compound: 5-Fu
    Growth inhibition against human HCT116 cells after 48 hrs by MTT assay
    Growth inhibition against human HCT116 cells after 48 hrs by MTT assay
    [PMID: 23999046]
    HCT-116 IC50
    27.76 μM
    Compound: 5-Fu
    Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
    [PMID: 23558238]
    HCT-116 IC50
    27.8 μM
    Compound: 5-FU
    Anticancer activity against human HCT116 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
    Anticancer activity against human HCT116 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
    [PMID: 26922233]
    HCT-116 IC50
    29.2 μM
    Compound: 5-Fu
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    [PMID: 28073676]
    HCT-116 IC50
    29.5 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
    [PMID: 27503679]
    HCT-116 IC50
    29.5 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    [PMID: 29232583]
    HCT-116 IC50
    29.58 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells assessed as cell viability after 48 hrs by MTT assay
    [PMID: 25841199]
    HCT-116 IC50
    3.03 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HCT116 cells after 24 hrs by trypan blue exclusion assay
    Cytotoxicity against human HCT116 cells after 24 hrs by trypan blue exclusion assay
    [PMID: 20163895]
    HCT-116 IC50
    3.24 μM
    Compound: 5-Fu
    Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
    Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
    [PMID: 23685571]
    HCT-116 IC50
    3.56 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT116 cells assessed as inhibition cell proliferation after 48 hrs by Sulforhodamine B assay
    Antiproliferative activity against human HCT116 cells assessed as inhibition cell proliferation after 48 hrs by Sulforhodamine B assay
    [PMID: 23305919]
    HCT-116 IC50
    31.72 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
    [PMID: 22483608]
    HCT-116 IC50
    32.26 μM
    Compound: 5-FU
    Anticancer activity against human HCT-116 cells assessed as inhibition of cell proliferation by MTT assay
    Anticancer activity against human HCT-116 cells assessed as inhibition of cell proliferation by MTT assay
    [PMID: 36439975]
    HCT-116 IC50
    36.2 μM
    Compound: 5-Fu
    Antiproliferative activity against human HCT116 cells assessed as cell-growth inhibition after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells assessed as cell-growth inhibition after 48 hrs by MTT assay
    [PMID: 25453794]
    HCT-116 IC50
    36.4 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
    [PMID: 23067549]
    HCT-116 IC50
    37.22 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability by MTT assay
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability by MTT assay
    [PMID: 34157389]
    HCT-116 IC50
    37.6 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    [PMID: 30108895]
    HCT-116 IC50
    38.3 μM
    Compound: 5-Fu
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    [PMID: 28110871]
    HCT-116 IC50
    38.3 μM
    Compound: 5-Fu
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    [PMID: 30142612]
    HCT-116 IC50
    38.3 μM
    Compound: 5-Fu
    Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by MTT assay
    [PMID: 26922223]
    HCT-116 IC50
    4 μM
    Compound: 5-FU
    Antitumor activity against human HCT116 cells after 24 hrs by MTT assay
    Antitumor activity against human HCT116 cells after 24 hrs by MTT assay
    [PMID: 20211564]
    HCT-116 IC50
    4 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    [PMID: 28623814]
    HCT-116 IC50
    4 μM
    Compound: 5-Fluorouracil
    Cytostatic activity against human HCT116 cells after 72 hrs by MTT assay
    Cytostatic activity against human HCT116 cells after 72 hrs by MTT assay
    [PMID: 22405290]
    HCT-116 IC50
    4 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
    Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
    [PMID: 22130132]
    HCT-116 IC50
    4 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT116 cells after 72 hrs by SRB assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by SRB assay
    [PMID: 29326016]
    HCT-116 IC50
    4.16 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    [PMID: 28458133]
    HCT-116 IC50
    4.3 μM
    Compound: 5-FU
    Antiproliferative activity in human HCT116 cells after 72 hrs by MTT assay
    Antiproliferative activity in human HCT116 cells after 72 hrs by MTT assay
    10.1039/C6MD00252H
    HCT-116 IC50
    4.3 μM
    Compound: 5-FU
    Cytotoxicity against human HCT-116 cells harboring p53 knock out gene assessed as reduction in cell viability incubated for 72 hrs by SRB assay
    Cytotoxicity against human HCT-116 cells harboring p53 knock out gene assessed as reduction in cell viability incubated for 72 hrs by SRB assay
    [PMID: 33321421]
    HCT-116 IC50
    4.42 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HCT116 cells expressing wild type p53 incubated for 72 hrs by MTS assay
    Cytotoxicity against human HCT116 cells expressing wild type p53 incubated for 72 hrs by MTS assay
    [PMID: 31158748]
    HCT-116 IC50
    4.5 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay
    Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay
    [PMID: 26222449]
    HCT-116 IC50
    4.52 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23644215]
    HCT-116 IC50
    4.6 μM
    Compound: 5-FU
    Anticancer activity against human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Anticancer activity against human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    [PMID: 33940466]
    HCT-116 IC50
    4.69 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HCT116 cells deficient in p53 incubated for 72 hrs by MTS assay
    Cytotoxicity against human HCT116 cells deficient in p53 incubated for 72 hrs by MTS assay
    [PMID: 31158748]
    HCT-116 IC50
    4.8 μg/mL
    Compound: 5-Fu
    Anticancer activity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay
    Anticancer activity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay
    [PMID: 25017036]
    HCT-116 IC50
    4.89 μM
    Compound: 5-FU
    Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    [PMID: 36331508]
    HCT-116 IC50
    4.9 μM
    Compound: 5-Fu
    Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
    Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
    10.1039/C4MD00209A
    HCT-116 IC50
    4.93 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells after 96 hrs by MTT assay
    Cytotoxicity against human HCT116 cells after 96 hrs by MTT assay
    [PMID: 15387639]
    HCT-116 IC50
    41.9 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 28532669]
    HCT-116 IC50
    44.06 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human HCT116 cells in presence of ubenimex after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells in presence of ubenimex after 48 hrs by MTT assay
    [PMID: 29202398]
    HCT-116 GI50
    5.47 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT116 cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by sulforhodamine B assay
    [PMID: 28716495]
    HCT-116 IC50
    5.53 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by MTS assay
    Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by MTS assay
    [PMID: 30472605]
    HCT-116 IC50
    5.53 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay
    [PMID: 27575478]
    HCT-116 IC50
    5.53 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay
    [PMID: 26703795]
    HCT-116 IC50
    5.53 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells by MTS assay
    Cytotoxicity against human HCT116 cells by MTS assay
    [PMID: 29843103]
    HCT-116 IC50
    5.53 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
    [PMID: 23665106]
    HCT-116 IC50
    5.78 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
    Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
    [PMID: 24378217]
    HCT-116 IC50
    5.78 μM
    Compound: 5-Fu
    Antiproliferative activity against human HCT-116 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HCT-116 cells after 72 hrs by MTT assay
    [PMID: 35609396]
    HCT-116 IC50
    53.84 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    [PMID: 29202398]
    HCT-116 IC50
    56.96 μM
    Compound: 5-Fuorouracil
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    [PMID: 27017265]
    HCT-116 IC50
    6 μg/mL
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
    Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
    [PMID: 22154835]
    HCT-116 IC50
    6 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay
    Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay
    [PMID: 25462277]
    HCT-116 IC50
    6 μM
    Compound: 5-Fu
    Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay
    Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay
    [PMID: 22409771]
    HCT-116 IC50
    6.1 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    [PMID: 33248852]
    HCT-116 IC50
    6.36 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT116 cells expressing p53 gene after 72 hrs by proliferative assay
    Antiproliferative activity against human HCT116 cells expressing p53 gene after 72 hrs by proliferative assay
    [PMID: 18469809]
    HCT-116 IC50
    6.5 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HCT116 cells after 48 hrs by CellTiter-Glo assay
    Cytotoxicity against human HCT116 cells after 48 hrs by CellTiter-Glo assay
    [PMID: 31999116]
    HCT-116 IC50
    6.86 μM
    Compound: 5-Fu
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 31877536]
    HCT-116 IC50
    6.86 μM
    Compound: 5-Fu
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell growth after 72 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells assessed as reduction in cell growth after 72 hrs by MTT assay
    [PMID: 31883693]
    HCT-116 IC50
    63.9 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay
    Cytotoxicity against human HCT116 cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay
    [PMID: 31416740]
    HCT-116 IC50
    68.71 μM
    Compound: 5-Fu
    Antiproliferative activity against human HCT116 cells measured after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells measured after 48 hrs by MTT assay
    [PMID: 27287368]
    HCT-116 IC50
    7.38 μM
    Compound: 5-FU
    Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    [PMID: 34170142]
    HCT-116 IC50
    7.77 μM
    Compound: 5-FU
    Antitumor activity against human HCT-116 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    Antitumor activity against human HCT-116 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    [PMID: 35777102]
    HCT-116 IC50
    8.32 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
    Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay
    [PMID: 24211021]
    HCT-116 IC50
    8.62 μM
    Compound: 5-FU
    Cytotoxicity in human HCT116 cells incubated for 48 hrs by MTT assay
    Cytotoxicity in human HCT116 cells incubated for 48 hrs by MTT assay
    [PMID: 28923381]
    HCT-116 IC50
    8.638 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay
    [PMID: 29223717]
    HCT-116 GI50
    8.8 nM
    Compound: 5FU
    Growth inhibition of human HCT116 cells after 48 hrs by SRB assay
    Growth inhibition of human HCT116 cells after 48 hrs by SRB assay
    [PMID: 23094992]
    HCT-116 IC50
    84.9 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human HCT-116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HCT-116 cells after 48 hrs by MTT assay
    [PMID: 27322756]
    HCT-116 GI50
    9.51 μM
    Compound: 5-FU
    Cytotoxicity against human HCT116 cells after 48 hrs by SRB assay
    Cytotoxicity against human HCT116 cells after 48 hrs by SRB assay
    10.1007/s00044-013-0798-7
    HCT-116 IC50
    9.88 μM
    Compound: 5-FU
    Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
    Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
    [PMID: 35635947]
    HCT-116 GI50
    9.9 μM
    Compound: 5-Fu
    Growth inhibition of human HCT116 cells after 48 hrs by SRB assay
    Growth inhibition of human HCT116 cells after 48 hrs by SRB assay
    [PMID: 22512908]
    HCT-116 IC50
    91.73 μM
    Compound: 5-FU
    Cytotoxicity in human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity in human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 35085721]
    HCT-15 CC50
    > 2512 μM
    Compound: 5-Fu
    Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay
    [PMID: 26727215]
    HCT-15 GI50
    0.11 μM
    Compound: 5-FU
    Anticancer activity against human HCT-15 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human HCT-15 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    HCT-15 GI50
    0.11 μM
    Compound: 5-FU
    Growth inhibition of human HCT15 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human HCT15 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    HCT-15 IC50
    10.86 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HCT-15 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay
    Antiproliferative activity against human HCT-15 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay
    [PMID: 32387836]
    HCT-15 IC50
    11.87 μM
    Compound: 5-FU
    Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay
    Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay
    [PMID: 30318440]
    HCT-15 IC50
    14.8 μM
    Compound: 5-Fu
    Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay
    [PMID: 26727215]
    HCT-15 IC50
    18.24 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT15 cells expressing p53 gene after 72 hrs by proliferative assay
    Antiproliferative activity against human HCT15 cells expressing p53 gene after 72 hrs by proliferative assay
    [PMID: 18469809]
    HCT-15 GI50
    21 μM
    Compound: 5-Fu
    Growth inhibition of human HCT15 cells after 48 hrs by SRB assay
    Growth inhibition of human HCT15 cells after 48 hrs by SRB assay
    [PMID: 22512908]
    HCT-15 GI50
    21.1 nM
    Compound: 5FU
    Growth inhibition of human HCT15 cells after 48 hrs by SRB assay
    Growth inhibition of human HCT15 cells after 48 hrs by SRB assay
    [PMID: 23094992]
    HCT-15 IC50
    3.6 μM
    Compound: 5-fluorouracil
    Anticancer activity against human HCT15 cells assessed as cell viability after 48 hrs by SRB assay
    Anticancer activity against human HCT15 cells assessed as cell viability after 48 hrs by SRB assay
    [PMID: 21074444]
    HCT-15 IC50
    33.68 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human HCT-15 cells assessed as cell growth inhibition by MTT assay
    Antiproliferative activity against human HCT-15 cells assessed as cell growth inhibition by MTT assay
    [PMID: 31945642]
    HCT-15 IC50
    4.5 μM
    Compound: 5-FU
    Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay
    [PMID: 24910974]
    HCT-15 IC50
    45.01 μM
    Compound: 5-FU
    Growth inhibition of human HCT15 cells after 24 hrs by MTT assay
    Growth inhibition of human HCT15 cells after 24 hrs by MTT assay
    [PMID: 28011220]
    HCT-15 IC50
    45.01 μM
    Compound: 5-FU
    Cytotoxicity against human HCT15 cells after 24 hrs by MTT assay
    Cytotoxicity against human HCT15 cells after 24 hrs by MTT assay
    [PMID: 23202484]
    HCT-15 IC50
    48 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT15 cells expressing p53 after 72 hrs by celltiter-glo assay
    Antiproliferative activity against human HCT15 cells expressing p53 after 72 hrs by celltiter-glo assay
    [PMID: 20873740]
    HCT-15 IC50
    6.61 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HCT15 cells assessed as inhibition of tumor growth after 24 hrs
    Cytotoxicity against human HCT15 cells assessed as inhibition of tumor growth after 24 hrs
    [PMID: 24657568]
    HCT-15 IC50
    7.53 μM
    Compound: 5-Fu
    Cytotoxicity against human HCT15 cells after 48 hrs by MTT assay
    Cytotoxicity against human HCT15 cells after 48 hrs by MTT assay
    [PMID: 29174813]
    HCT-15 IC50
    7.53 μM
    Compound: 5-FU
    Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay
    Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay
    [PMID: 30677614]
    HCT-15 IC50
    8.24 μM
    Compound: 5-FU
    Anticancer activity against human HCT-15 cells incubated for 72 hrs by MTT assay
    Anticancer activity against human HCT-15 cells incubated for 72 hrs by MTT assay
    [PMID: 35367708]
    HCT-8 IC50
    0.2 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human HCT8 after 24 hrs by MTT assay
    Cytotoxicity against human HCT8 after 24 hrs by MTT assay
    [PMID: 19338315]
    HCT-8 IC50
    0.54 μg/mL
    Compound: 5-FU, 5-fluorouracil
    Cytotoxicity against human HCT8 cells by MTT assay
    Cytotoxicity against human HCT8 cells by MTT assay
    [PMID: 18205316]
    HCT-8 IC50
    0.91 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT8 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    Antiproliferative activity against human HCT8 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    [PMID: 25675144]
    HCT-8 IC50
    2.2 μM
    Compound: 5-FU
    Cytotoxicity against human HCT-8 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
    Cytotoxicity against human HCT-8 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
    [PMID: 33321421]
    HCT-8 IC50
    28.9 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay
    [PMID: 30429977]
    HCT-8 IC50
    28.9 μM
    Compound: 5-FU
    Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay
    [PMID: 30037494]
    HCT-8 IC50
    3.54 μM
    Compound: 5-FU
    Cytotoxicity against human HCT8 cells assessed as growth inhibition rate after 96 hrs by MTT assay
    Cytotoxicity against human HCT8 cells assessed as growth inhibition rate after 96 hrs by MTT assay
    [PMID: 25203783]
    HCT-8 IC50
    32.31 μM
    Compound: 5-FU
    Cytotoxicity against human HCT8 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human HCT8 cells assessed as growth inhibition after 48 hrs by MTT assay
    [PMID: 26873416]
    HCT-8 IC50
    36.638 μM
    Compound: 5-FU
    Antiproliferative activity against 5-FU resistant human HCT8 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    Antiproliferative activity against 5-FU resistant human HCT8 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    [PMID: 25675144]
    HCT-8 IC50
    4.2 μM
    Compound: 5-Fu
    Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay
    Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay
    [PMID: 16499317]
    HCT-8 IC50
    47 μM
    Compound: 5-FU
    Cytotoxicity against 5-FU resistant human HCT-8 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
    Cytotoxicity against 5-FU resistant human HCT-8 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
    [PMID: 33321421]
    HCT-8 IC50
    5.38 μM
    Compound: 5-Fu
    Cytotoxicity against human HCT8 cells by MTT method
    Cytotoxicity against human HCT8 cells by MTT method
    [PMID: 23164710]
    HCT-8 IC50
    6.3 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HCT8 cells after 72 hrs by MTT assay
    Cytotoxicity against human HCT8 cells after 72 hrs by MTT assay
    [PMID: 26227777]
    HCT-8 IC50
    6.92 μM
    Compound: 5-Fu
    Antiproliferative activity against human HCT8 cells by MTT assay
    Antiproliferative activity against human HCT8 cells by MTT assay
    [PMID: 24095094]
    HEK293 IC50
    19.6 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HEK293 cells by MTT assay
    Antiproliferative activity against human HEK293 cells by MTT assay
    [PMID: 29798826]
    HEK293 IC50
    2.15 μM
    Compound: 5-Florouracil
    Cytotoxicity against Homo sapiens (human) HEK293 cells assessed as inhibition of cell proliferation after 24 hr by MTT assay
    Cytotoxicity against Homo sapiens (human) HEK293 cells assessed as inhibition of cell proliferation after 24 hr by MTT assay
    10.1007/s00044-012-0260-2
    HEK293 IC50
    40 μM
    Compound: 5 Fluorouracil
    Cytotoxicity against human HEK293 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human HEK293 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    [PMID: 27496212]
    HEK293 IC50
    41.01 μM
    Compound: 5-Fu
    Antiproliferative activity against human HEK293 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HEK293 cells after 72 hrs by MTT assay
    [PMID: 35609396]
    HEK293 IC50
    42.9 μM
    Compound: 5-FU
    Cytotoxicity against human HEK293 cells after 2 days by alamar blue assay
    Cytotoxicity against human HEK293 cells after 2 days by alamar blue assay
    [PMID: 22093761]
    HEK293 IC50
    48.7 μM
    Compound: 5-FU
    Antiproliferative activity against HEK293 cells after 24 hrs by MTT assay
    Antiproliferative activity against HEK293 cells after 24 hrs by MTT assay
    [PMID: 25198997]
    HEK293 IC50
    79.32 μM
    Compound: 5-FU
    Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 32203786]
    HEK-293T IC50
    > 100 μM
    Compound: 5-FU
    Growth inhibition of HEK293T cells after 24 hrs by MTT assay
    Growth inhibition of HEK293T cells after 24 hrs by MTT assay
    [PMID: 28011220]
    HEL IC50
    15.98 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HEL cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HEL cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 29133049]
    HEL IC50
    32.27 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
    Antiproliferative activity against human HEL cells after 48 hrs by MTT assay
    [PMID: 27322756]
    HeLa IC50
    > 100 μM
    Compound: 5-FU
    Antiproliferative activity against human p53 deficient HeLa cells after 72 hrs by celltiter-glo assay
    Antiproliferative activity against human p53 deficient HeLa cells after 72 hrs by celltiter-glo assay
    [PMID: 20873740]
    HeLa IC50
    > 100 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    [PMID: 26617970]
    HeLa IC50
    > 100 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells by MTT assay
    Cytotoxicity against human HeLa cells by MTT assay
    [PMID: 21689869]
    HeLa IC50
    > 100 μM
    Compound: 5-FU
    Antiproliferative activity against p53 deficient human HeLa cells after 72 hrs
    Antiproliferative activity against p53 deficient human HeLa cells after 72 hrs
    [PMID: 18469809]
    HeLa IC50
    > 20 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    [PMID: 36331508]
    HeLa IC50
    > 20 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTS assay
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTS assay
    [PMID: 30472605]
    HeLa IC50
    > 50 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 33538581]
    HeLa IC50
    0.04 mg/mL
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells after 3 days MTT assay
    Cytotoxicity against human HeLa cells after 3 days MTT assay
    [PMID: 22796042]
    HeLa EC50
    0.23 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    [PMID: 12027739]
    HeLa IC50
    0.23 μM
    Compound: 1, 5-FU
    Cytostatic activity against thymidine-kinase deficient human HeLa cells after 72 hrs by cell counting
    Cytostatic activity against thymidine-kinase deficient human HeLa cells after 72 hrs by cell counting
    [PMID: 21892829]
    HeLa IC50
    0.28 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
    [PMID: 22959518]
    HeLa IC50
    0.44 μM
    Compound: 5-Fluoro uracil
    Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
    [PMID: 19689125]
    HeLa IC50
    0.45 μM
    Compound: 5-FU
    Cytostatic activity against human HeLa cells after 3 days by coulter counting analysis
    Cytostatic activity against human HeLa cells after 3 days by coulter counting analysis
    [PMID: 21330014]
    HeLa IC50
    0.54 μM
    Compound: 5-Fluorouracil
    Cytostatic activity against human HeLa cells after 3 days by coulter counter analysis
    Cytostatic activity against human HeLa cells after 3 days by coulter counter analysis
    [PMID: 22405290]
    HeLa IC50
    0.54 μM
    Compound: 5-Fluorouracil
    Anti-proliferative activity against human HeLa cells measured after 4 days by coulter counter method
    Anti-proliferative activity against human HeLa cells measured after 4 days by coulter counter method
    [PMID: 27750154]
    HeLa IC50
    0.54 μM
    Compound: 5-Fluorouracil
    Cytostatic activity against human HeLa cells assessed as inhibition of proliferation after 72 hrs by Coulter cell counting method
    Cytostatic activity against human HeLa cells assessed as inhibition of proliferation after 72 hrs by Coulter cell counting method
    [PMID: 24906510]
    HeLa IC50
    0.54 μM
    Compound: 5FU
    Cytotoxicity against human HeLa cells assessed as reduction in cell number after 72 hrs by cell counting assay
    Cytotoxicity against human HeLa cells assessed as reduction in cell number after 72 hrs by cell counting assay
    [PMID: 24631358]
    HeLa IC50
    0.54 μM
    Compound: 1, 5-FU
    Cytostatic activity against human HeLa cells after 72 hrs by cell counting
    Cytostatic activity against human HeLa cells after 72 hrs by cell counting
    [PMID: 21892829]
    HeLa IC50
    0.57 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells after 4 days by coulter counter analysis
    Cytotoxicity against human HeLa cells after 4 days by coulter counter analysis
    [PMID: 21232828]
    HeLa IC50
    0.77 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
    [PMID: 18440233]
    HeLa IC50
    0.8 μg/mL
    Compound: 5-FU
    Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
    [PMID: 23994872]
    HeLa IC50
    0.887 μg/mL
    Compound: 5-Fluorouracil
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 24021891]
    HeLa IC50
    1.01 μg/mL
    Compound: 5-FU
    Cytotoxicity against human HeLa cells after 48 hrs by SRB assay
    Cytotoxicity against human HeLa cells after 48 hrs by SRB assay
    [PMID: 19932530]
    HeLa IC50
    1.1 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HeLa cells after 24 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 24 hrs by MTT assay
    [PMID: 24060486]
    HeLa IC50
    1.28 μg/mL
    Compound: 5-Fluorouracil
    Cytotoxicity against human HeLa cells after 24 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 24 hrs by MTT assay
    [PMID: 23352638]
    HeLa IC50
    1.3 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells after 24 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 24 hrs by MTT assay
    [PMID: 24835633]
    HeLa IC50
    1.4 x 10-1 μg/mL
    Compound: fluorouracil
    Cytotoxicity against human HeLa cells by MTT assay
    Cytotoxicity against human HeLa cells by MTT assay
    [PMID: 22011319]
    HeLa IC50
    1.4 μM
    Compound: 5-F
    Cytotoxicity against human HeLa cells after 24 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 24 hrs by MTT assay
    [PMID: 28254697]
    HeLa IC50
    1.5 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay
    Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay
    [PMID: 26629861]
    HeLa IC50
    1.6 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay
    [PMID: 31546197]
    HeLa IC50
    1.6 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay
    Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay
    [PMID: 27720296]
    HeLa IC50
    1.8 μM
    Compound: 5-Fluoro uracilc
    Cytotoxicity against human HeLa cells assessed as growth inhibition after 24 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as growth inhibition after 24 hrs by MTT assay
    [PMID: 24641975]
    HeLa IC50
    1.8 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    [PMID: 27528432]
    HeLa IC50
    1.8 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HeLa cells by MTT assay
    Antiproliferative activity against human HeLa cells by MTT assay
    [PMID: 29798826]
    HeLa IC50
    1.86 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 28431881]
    HeLa IC50
    1.9 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay
    Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay
    [PMID: 27561719]
    HeLa IC50
    1.94 μM
    Compound: 5-FU
    Antitumor activity against human HeLa cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay
    Antitumor activity against human HeLa cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay
    [PMID: 36324491]
    HeLa IC50
    10 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 20405881]
    HeLa IC50
    10 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 19919065]
    HeLa IC50
    10 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 19795843]
    HeLa IC50
    10 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 19618920]
    HeLa GI50
    10 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 19572613]
    HeLa IC50
    10.31 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    [PMID: 21524829]
    HeLa IC50
    10.36 μM
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells by MTT assay
    Cytotoxicity against human HeLa cells by MTT assay
    [PMID: 22801644]
    HeLa IC50
    10.72 μg/mL
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as cell growth inhibition after 72 hrs by MTT assay
    [PMID: 27262600]
    HeLa IC50
    10.72 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HeLa assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 30709651]
    HeLa IC50
    10.75 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
    [PMID: 30318440]
    HeLa IC50
    110.16 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 21962523]
    HeLa IC50
    12 μM
    Compound: 5-Fu
    Anticancer activity against human HeLa cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    Anticancer activity against human HeLa cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    [PMID: 25086915]
    HeLa IC50
    12.3 μM
    Compound: 5-FU
    Anticancer activity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Anticancer activity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    [PMID: 33940466]
    HeLa IC50
    12.7 μM
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    [PMID: 32987314]
    HeLa IC50
    120.4 μM
    Compound: 5-FU
    Cytotoxicity in human HeLa cells assessed as growth inhibition incubated for 24 hrs by MTT assay
    Cytotoxicity in human HeLa cells assessed as growth inhibition incubated for 24 hrs by MTT assay
    [PMID: 31128448]
    HeLa IC50
    13.45 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HeLa cells assessed as cell survival after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as cell survival after 48 hrs by MTT assay
    [PMID: 25506718]
    HeLa IC50
    13.9 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by WST8 assay
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by WST8 assay
    [PMID: 28488862]
    HeLa IC50
    13.9 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HeLa cells assessed as decrease in cell viability measured after 72 hrs by WST-8 assay
    Cytotoxicity against human HeLa cells assessed as decrease in cell viability measured after 72 hrs by WST-8 assay
    [PMID: 33383442]
    HeLa IC50
    13.9 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HeLa cells incubated for 72 hrs by WST-8 assay
    Cytotoxicity against human HeLa cells incubated for 72 hrs by WST-8 assay
    [PMID: 32125158]
    HeLa IC50
    132.99 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 27322756]
    HeLa IC50
    14.78 μM
    Compound: 5-FU
    Antitumor activity against human HeLa cells assessed as growth inhibition measured after 48 hrs by MTT assay
    Antitumor activity against human HeLa cells assessed as growth inhibition measured after 48 hrs by MTT assay
    [PMID: 23313635]
    HeLa IC50
    14.93 μM
    Compound: 5-Fluoruracil
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    [PMID: 22555152]
    HeLa IC50
    142.6 μM
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 23356786]
    HeLa GI50
    15 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells assessed as growth inhibition after 48 hrs by SRB assay
    Antiproliferative activity against human HeLa cells assessed as growth inhibition after 48 hrs by SRB assay
    [PMID: 31376562]
    HeLa GI50
    15 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay
    Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay
    [PMID: 28728108]
    HeLa GI50
    15 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HeLa cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human HeLa cells after 48 hrs by sulforhodamine B assay
    [PMID: 25752525]
    HeLa IC50
    15.02 μM
    Compound: 5-FLU
    Cytotoxicity against human HeLa cells assessed as growth inhibition by MTT assay
    Cytotoxicity against human HeLa cells assessed as growth inhibition by MTT assay
    [PMID: 32331934]
    HeLa IC50
    15.5 μM
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    [PMID: 32987314]
    HeLa IC50
    15.99 μM
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
    [PMID: 22687745]
    HeLa IC50
    16 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells after 3 days by MTT assay
    Antiproliferative activity against human HeLa cells after 3 days by MTT assay
    [PMID: 18424155]
    HeLa IC50
    16.1 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells by MTT assay
    Cytotoxicity against human HeLa cells by MTT assay
    [PMID: 21515044]
    HeLa IC50
    16.32 μM
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells after 24 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 24 hrs by MTT assay
    [PMID: 22182926]
    HeLa IC50
    16.32 μM
    Compound: 5-Fu
    Growth inhibition of human HeLa cells after 48 hrs by MTT assay
    Growth inhibition of human HeLa cells after 48 hrs by MTT assay
    [PMID: 23353737]
    HeLa IC50
    16.32 μM
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells by after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells by after 48 hrs by MTT assay
    [PMID: 22579780]
    HeLa IC50
    16.52 μM
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 23920246]
    HeLa IC50
    17.21 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells after 48 hrs by CCK-8 assay
    Antiproliferative activity against human HeLa cells after 48 hrs by CCK-8 assay
    [PMID: 27542307]
    HeLa IC50
    17.21 μM
    Compound: 5-Fu
    Antiproliferative activity against human HeLa cells after 48 hrs by CCK8 assay
    Antiproliferative activity against human HeLa cells after 48 hrs by CCK8 assay
    [PMID: 26786698]
    HeLa IC50
    18.1 μM
    Compound: 5-Fu
    Antiproliferative activity against human HeLa cells assessed as cell-growth inhibition after 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells assessed as cell-growth inhibition after 48 hrs by MTT assay
    [PMID: 25453794]
    HeLa GI50
    19 μM
    Compound: 5-FU
    Growth inhibition of human HeLa cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human HeLa cells after 48 hrs by sulforhodamine B assay
    [PMID: 19664930]
    HeLa IC50
    2.3 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 24547794]
    HeLa IC50
    2.6 μM
    Compound: 5-FU
    Cytostatic activity against human HeLa cells after 72 hrs by Coulter counting
    Cytostatic activity against human HeLa cells after 72 hrs by Coulter counting
    [PMID: 25435471]
    HeLa IC50
    2.78 μM
    Compound: FU
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 24941129]
    HeLa IC50
    2.9 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay
    [PMID: 28838694]
    HeLa IC50
    20.4 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay
    Cytotoxicity against human HeLa cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay
    [PMID: 31416740]
    HeLa IC50
    20.6 μM
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
    [PMID: 32987314]
    HeLa IC50
    23.33 μM
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 24953029]
    HeLa IC50
    24.34 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth by SRB assay
    Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth by SRB assay
    [PMID: 35594653]
    HeLa IC50
    26.18 μM
    Compound: 5-Fu
    Antiproliferative activity against human HeLa cells assessed as cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells assessed as cell viability after 72 hrs by MTT assay
    [PMID: 26922223]
    HeLa IC50
    28 μM
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells assessed as decrease in cell viability by MTT assay
    Cytotoxicity against human HeLa cells assessed as decrease in cell viability by MTT assay
    [PMID: 29489361]
    HeLa IC50
    28.2 μM
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 27561718]
    HeLa IC50
    28.22 μM
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    [PMID: 30568759]
    HeLa IC50
    3.2 μg/mL
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 96 hrs
    Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 96 hrs
    [PMID: 29673982]
    HeLa IC50
    3.25 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT method
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT method
    [PMID: 23018096]
    HeLa IC50
    3.4 μM
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
    [PMID: 23792763]
    HeLa IC50
    3.82 μg/mL
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    [PMID: 29100732]
    HeLa IC50
    30.2 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 29305189]
    HeLa GI50
    30.21 μM
    Compound: 5-Fu
    Antiproliferative activity against human HeLa cells after 24 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 24 hrs by MTT assay
    [PMID: 24934992]
    HeLa IC50
    30.21 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 30007564]
    HeLa IC50
    30.71 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth by MTT assay
    Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth by MTT assay
    [PMID: 36089111]
    HeLa EC50
    31.02 μg/mL
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 21889345]
    HeLa IC50
    32.1 μM
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 34883453]
    HeLa IC50
    35.34 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 25151580]
    HeLa IC50
    35.34 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 24378217]
    HeLa IC50
    36.53 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 25462253]
    HeLa IC50
    4 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells after 3 days by MTT assay
    Cytotoxicity against human HeLa cells after 3 days by MTT assay
    [PMID: 21612935]
    HeLa IC50
    4 μM
    Compound: 5-FU
    Growth inhibition of human HeLa cells after 72 hrs by MTT assay
    Growth inhibition of human HeLa cells after 72 hrs by MTT assay
    [PMID: 18640746]
    HeLa IC50
    4.3 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HeLa cells by MTT assay
    Antiproliferative activity against human HeLa cells by MTT assay
    [PMID: 31546197]
    HeLa IC50
    4.6 μM
    Compound: 5-Fluorouracil
    Anticancer activity against human HeLa cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay
    Anticancer activity against human HeLa cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay
    [PMID: 26231080]
    HeLa IC50
    4.71 μM
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
    10.1039/C4MD00209A
    HeLa IC50
    4.9 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human HeLa cells after 48 hrs by sulforhodamine B assay
    [PMID: 24910974]
    HeLa IC50
    41.46 μM
    Compound: 5-Fu
    Antitumor activity against human HeLa cells after 72 hrs by MTT assay
    Antitumor activity against human HeLa cells after 72 hrs by MTT assay
    [PMID: 21486694]
    HeLa IC50
    42.74 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells assessed as reduction in cell viability by MTT assay
    Antiproliferative activity against human HeLa cells assessed as reduction in cell viability by MTT assay
    [PMID: 34157389]
    HeLa IC50
    43 μM
    Compound: 5-fu
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 22304344]
    HeLa IC50
    43.71 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells after 72 hrs by MTS assay
    Antiproliferative activity against human HeLa cells after 72 hrs by MTS assay
    [PMID: 26703795]
    HeLa IC50
    43.71 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    [PMID: 23665106]
    HeLa IC50
    5.3 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by WST8 assay
    Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by WST8 assay
    [PMID: 28558970]
    HeLa IC50
    5.7 μg/mL
    Compound: 5-Fu
    Anticancer activity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay
    Anticancer activity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay
    [PMID: 25017036]
    HeLa IC50
    5.78 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    [PMID: 36242987]
    HeLa IC50
    5.8 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human HeLa cells after 72 hrs by WST8 assay
    Antiproliferative activity against human HeLa cells after 72 hrs by WST8 assay
    [PMID: 25919052]
    HeLa IC50
    5.8 μM
    Compound: 5-FU
    Antiproliferation activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by WST-8 assay
    Antiproliferation activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by WST-8 assay
    [PMID: 27311895]
    HeLa IC50
    50 μM
    Compound: 5-Fu
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 31057737]
    HeLa IC50
    56.5 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay
    10.1039/C6MD00234J
    HeLa IC50
    57.17 μM
    Compound: 5-Fu
    Antiproliferative activity against human HeLa cells measured after 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells measured after 48 hrs by MTT assay
    [PMID: 27287368]
    HeLa IC50
    6.23 μM
    Compound: FUra
    Cytotoxicity against human HeLa cells after 72 hrs by SRB assay
    Cytotoxicity against human HeLa cells after 72 hrs by SRB assay
    [PMID: 27073055]
    HeLa IC50
    6.23 μM
    Compound: FUra
    Cytotoxicity against human HeLa cells after 72 hrs by SRB assay
    Cytotoxicity against human HeLa cells after 72 hrs by SRB assay
    [PMID: 23867603]
    HeLa IC50
    6.23 μM
    Compound: FUra
    Cytotoxicity against human HeLa cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay
    Cytotoxicity against human HeLa cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay
    [PMID: 27501415]
    HeLa IC50
    6.4 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HeLa cells after 72 hrs by WST-8 assay
    Antiproliferative activity against human HeLa cells after 72 hrs by WST-8 assay
    [PMID: 26606140]
    HeLa IC50
    62.2 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells after 48 hrs by MTS assay
    Antiproliferative activity against human HeLa cells after 48 hrs by MTS assay
    [PMID: 28152430]
    HeLa IC50
    63.4 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 23067549]
    HeLa IC50
    64.2 μM
    Compound: 5-Fu
    Antitumor activity against human HeLa cells by MTT assay
    Antitumor activity against human HeLa cells by MTT assay
    [PMID: 20171096]
    HeLa IC50
    66.5 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay
    [PMID: 26291038]
    HeLa IC50
    7 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by MTT assay
    [PMID: 29908443]
    HeLa IC50
    7.34 μM
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells after 2 days by MTT assay
    Cytotoxicity against human HeLa cells after 2 days by MTT assay
    [PMID: 24767839]
    HeLa IC50
    7.34 μM
    Compound: 5-Fu
    Growth inhibition against human HeLa cells after 48 hrs by MTT assay
    Growth inhibition against human HeLa cells after 48 hrs by MTT assay
    [PMID: 23999046]
    HeLa IC50
    7.34 μM
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 23558238]
    HeLa EC50
    79.79 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
    [PMID: 20409617]
    HeLa IC50
    8.317 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 26301558]
    HeLa IC50
    8.81 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay
    [PMID: 31734024]
    HeLa IC50
    8.81 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    [PMID: 29133046]
    HeLa IC50
    8.81 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    [PMID: 28525845]
    HeLa IC50
    8.81 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    [PMID: 27875779]
    HeLa IC50
    8.93 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
    Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
    [PMID: 25959813]
    HeLa IC50
    80.48 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 24565905]
    HeLa IC50
    82.2 μM
    Compound: 5-Fu
    Cytotoxicity against human HeLa cells after 48 hrs by CCK-8 assay
    Cytotoxicity against human HeLa cells after 48 hrs by CCK-8 assay
    [PMID: 22244588]
    HeLa IC50
    82.27 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay
    [PMID: 26873416]
    HeLa IC50
    9.02 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 28363444]
    HeLa IC50
    9.09 μM
    Compound: 5-FU
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay
    [PMID: 25529742]
    HeLa IC50
    9.5 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 48 hrs by MTT assay
    [PMID: 23002924]
    HeLa IC50
    9.7 μM
    Compound: 5-FU
    Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
    Cytotoxicity against human HeLa cells after 72 hrs by MTT assay
    [PMID: 20494492]
    HeLa IC50
    9.7 μM
    Compound: 5-FU
    Cytotoxicity against Homo sapiens (human) HeLa cells by MTT assay
    Cytotoxicity against Homo sapiens (human) HeLa cells by MTT assay
    10.1007/s00044-010-9395-1
    HeLa S3 ED50
    2.47 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human HeLaS3 cells after 3 days by trypan blue exclusion technique
    Cytotoxicity against human HeLaS3 cells after 3 days by trypan blue exclusion technique
    [PMID: 1800632]
    HeLa S3 IC50
    5.4 μM
    Compound: Fluorouracil
    Cytotoxicity against human HeLaS3 cells after 72 hrs by WST1 assay
    Cytotoxicity against human HeLaS3 cells after 72 hrs by WST1 assay
    [PMID: 15387656]
    HeLa S3 IC50
    5.4 μM
    Compound: fluorouracil
    Cytotoxicity against human HeLaS3 cells by WST1 assay
    Cytotoxicity against human HeLaS3 cells by WST1 assay
    [PMID: 15568771]
    Hep 3B2 ED50
    0.6 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human Hep3B cells by MTT assay
    Cytotoxicity against human Hep3B cells by MTT assay
    [PMID: 16309328]
    Hep 3B2 IC50
    0.6 μM
    Compound: 5-Fu
    Cytotoxicity against human Hep3B cells by MTT assay
    Cytotoxicity against human Hep3B cells by MTT assay
    [PMID: 18606546]
    Hep 3B2 IC50
    0.6 μM
    Compound: 5-Fu
    Cytotoxicity against human Hep 3B cells by MTT microassay
    Cytotoxicity against human Hep 3B cells by MTT microassay
    [PMID: 17320246]
    Hep 3B2 IC50
    1.5 μM
    Compound: 5-Fu
    Cytotoxicity against human Hep3B cells assessed as induction of cell death incubated for 2 days by MTT assay
    Cytotoxicity against human Hep3B cells assessed as induction of cell death incubated for 2 days by MTT assay
    [PMID: 26259802]
    Hep 3B2 IC50
    10.53 μM
    Compound: 5-Fu
    Cytotoxic activity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxic activity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay
    [PMID: 27993516]
    Hep 3B2 IC50
    10.53 μM
    Compound: 5-Fu
    Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay
    Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay
    [PMID: 26883148]
    Hep 3B2 IC50
    10.53 μM
    Compound: 5FU
    Cytotoxicity against human Hep3B cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay
    Cytotoxicity against human Hep3B cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay
    [PMID: 28038327]
    Hep 3B2 IC50
    11.9 μM
    Compound: 5-FU
    Cytotoxicity against human Hep3B cells by MTT assay
    Cytotoxicity against human Hep3B cells by MTT assay
    [PMID: 28371676]
    Hep 3B2 IC50
    17.53 μM
    Compound: 5-Fu
    Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay
    Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay
    [PMID: 27133593]
    Hep 3B2 IC50
    2.66 μM
    Compound: 5-FU
    Cytotoxicity against human Hep3B cells by MTT assay
    Cytotoxicity against human Hep3B cells by MTT assay
    [PMID: 28262527]
    Hep 3B2 IC50
    22.99 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay
    [PMID: 27189676]
    Hep 3B2 IC50
    49.72 μM
    Compound: 5-FU
    Cytotoxicity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay
    [PMID: 28174107]
    Hep 3B2 ED50
    7.15 x 10-2 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human Hep3B cells by MTT assay
    Cytotoxicity against human Hep3B cells by MTT assay
    [PMID: 11908984]
    Hep 3B2 IC50
    7.2 x 10-2 μg/mL
    Compound: 5-Fu
    Cytotoxicity against human Hep3B cells by MTT assay
    Cytotoxicity against human Hep3B cells by MTT assay
    [PMID: 16038565]
    Hep 3B2 IC50
    9.36 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human Hep3B cells assessed as cell growth inhibition by MTT assay
    Cytotoxicity against human Hep3B cells assessed as cell growth inhibition by MTT assay
    [PMID: 27913179]
    HEp-2 IC50
    > 100 μM
    Compound: 5-FU
    Antiproliferative activity against human Hep2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human Hep2 cells after 72 hrs by MTT assay
    [PMID: 21524829]
    HEp-2 IC50
    0.3 μM
    Compound: 5-fluorouracil
    Anticancer activity against human Hep2 cells assessed as cell viability after 48 hrs by SRB assay
    Anticancer activity against human Hep2 cells assessed as cell viability after 48 hrs by SRB assay
    [PMID: 21074444]
    HEp-2 IC50
    128.7 μM
    Compound: 5-Fu
    Cytotoxicity against human Hep2 cells after 72 hrs by MTT assay
    Cytotoxicity against human Hep2 cells after 72 hrs by MTT assay
    [PMID: 23792763]
    HEp-2 IC50
    128.7 μM
    Compound: 5-FU
    Antiproliferative activity against human Hep2 cells after 72 hrs by MTT method
    Antiproliferative activity against human Hep2 cells after 72 hrs by MTT method
    [PMID: 17524655]
    HEp-2 IC50
    2 μM
    Compound: 5-Fu
    Cytotoxicity against Homo sapiens (human) Hep2 cells by SRB assay
    Cytotoxicity against Homo sapiens (human) Hep2 cells by SRB assay
    10.1007/s00044-010-9500-5
    HEp-2 IC50
    24.58 μM
    Compound: 5-Fu
    Cytotoxicity against human Hep2 cells by MTT assay
    Cytotoxicity against human Hep2 cells by MTT assay
    [PMID: 22801644]
    HEp-2 IC50
    4.5 μM
    Compound: 5-FU
    Antiproliferative activity against human Hep2 cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human Hep2 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23501113]
    HepG2 IC50
    > 10 μM
    Compound: 5-FU
    Growth inhibition of human HepG2 cells after 72 hrs by MTS assay
    Growth inhibition of human HepG2 cells after 72 hrs by MTS assay
    [PMID: 27704811]
    HepG2 IC50
    > 100 μM
    Compound: 5-FU
    Antitumor activity against human HepG2 cells assessed as growth inhibition measured after 48 hrs by MTT assay
    Antitumor activity against human HepG2 cells assessed as growth inhibition measured after 48 hrs by MTT assay
    [PMID: 23313635]
    HepG2 IC50
    > 100 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay
    Cytotoxicity against human HepG2 cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay
    [PMID: 31416740]
    HepG2 IC50
    > 150 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by MTT assay
    [PMID: 26320625]
    HepG2 IC50
    > 30 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    [PMID: 33248852]
    HepG2 IC50
    0.061 mM
    Compound: 5-Fluorouracil
    Cytotoxicity in human HepG2 cells assessed as reduction in cell viability by MTT assay
    Cytotoxicity in human HepG2 cells assessed as reduction in cell viability by MTT assay
    [PMID: 28334654]
    HepG2 IC50
    0.07 mM
    Compound: 5-FU
    Cytotoxicity against Homo sapiens (human) HepG2 cells assessed as inhibition of cell survival after 96 hr
    Cytotoxicity against Homo sapiens (human) HepG2 cells assessed as inhibition of cell survival after 96 hr
    10.1007/s00044-012-0201-0
    HepG2 IC50
    0.52 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
    Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
    [PMID: 32485532]
    HepG2 IC50
    1.3 μg/mL
    Compound: 5-Fluorouracil
    Cytotoxicity against human HepG2 cells by MTT assay
    Cytotoxicity against human HepG2 cells by MTT assay
    [PMID: 16499328]
    HepG2 IC50
    1.3 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT method
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT method
    [PMID: 23018096]
    HepG2 IC50
    1.3 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HepG2 cells assessed as cell growth inhibition by MTT assay
    Cytotoxicity against human HepG2 cells assessed as cell growth inhibition by MTT assay
    [PMID: 27561719]
    HepG2 IC50
    1.4 μM
    Compound: 5-F
    Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay
    [PMID: 28254697]
    HepG2 IC50
    1.6 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    [PMID: 31546197]
    HepG2 IC50
    1.7 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HepG2 cells by MTT assay
    Antiproliferative activity against human HepG2 cells by MTT assay
    [PMID: 29798826]
    HepG2 IC50
    1.8 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HepG2 cells assessed as cell growth inhibition by MTT assay
    Cytotoxicity against human HepG2 cells assessed as cell growth inhibition by MTT assay
    [PMID: 27720296]
    HepG2 IC50
    10 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 23800391]
    HepG2 IC50
    10.17 μM
    Compound: 5FU
    Cytotoxicity against human HepG2 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay
    Cytotoxicity against human HepG2 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay
    [PMID: 28038327]
    HepG2 IC50
    10.3 μM
    Compound: 5-Fu
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    10.1039/C6MD00169F
    HepG2 IC50
    10.4 μM
    Compound: 5-Fu
    Cytotoxicity in human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Cytotoxicity in human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    [PMID: 28987604]
    HepG2 IC50
    10.45 μM
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells by MTT assay
    Cytotoxicity against human HepG2 cells by MTT assay
    [PMID: 22801644]
    HepG2 IC50
    10.53 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay
    [PMID: 28174107]
    HepG2 IC50
    11.68 μM
    Compound: 5-Fu
    Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    [PMID: 35259487]
    HepG2 IC50
    110.01 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 21962523]
    HepG2 IC50
    112.1 μM
    Compound: 5-FU
    Cytotoxicity in human HePG2 cells assessed as growth inhibition incubated for 24 hrs by MTT assay
    Cytotoxicity in human HePG2 cells assessed as growth inhibition incubated for 24 hrs by MTT assay
    [PMID: 31128448]
    HepG2 IC50
    12 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HepG2 cells after 6 days by MTT assay
    Cytotoxicity against human HepG2 cells after 6 days by MTT assay
    [PMID: 29786436]
    HepG2 IC50
    12.48 μM
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells after 48 hrs by CCK-8 assay
    Cytotoxicity against human HepG2 cells after 48 hrs by CCK-8 assay
    [PMID: 24013415]
    HepG2 IC50
    13.31 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 28363444]
    HepG2 IC50
    13.54 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 27322756]
    HepG2 IC50
    14.52 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human HepG2 cells in presence of ubenimex after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells in presence of ubenimex after 48 hrs by MTT assay
    [PMID: 29202398]
    HepG2 IC50
    15.74 μM
    Compound: 5-Fu
    Antiproliferative activity against human HepG2 cells after 24 hrs by CCK-8 assay
    Antiproliferative activity against human HepG2 cells after 24 hrs by CCK-8 assay
    [PMID: 29499490]
    HepG2 IC50
    15.92 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 22209486]
    HepG2 IC50
    15.92 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells by MTT assay
    Antiproliferative activity against human HepG2 cells by MTT assay
    [PMID: 30359819]
    HepG2 IC50
    16.42 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
    [PMID: 26227777]
    HepG2 IC50
    17.2 μM
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 28117202]
    HepG2 IC50
    17.44 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells incubated for 48 to 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells incubated for 48 to 72 hrs by MTT assay
    [PMID: 28395218]
    HepG2 IC50
    17.57 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay
    [PMID: 37122546]
    HepG2 IC50
    174.5 μM
    Compound: 5-Fuorouracil
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 27017265]
    HepG2 IC50
    18.35 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 29202398]
    HepG2 IC50
    18.85 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HepG2 after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 after 48 hrs by MTT assay
    [PMID: 21486698]
    HepG2 IC50
    18.9 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    [PMID: 33740546]
    HepG2 IC50
    18.98 μM
    Compound: 5-Fu
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    [PMID: 35609396]
    HepG2 IC50
    18.98 μM
    Compound: 5-FU
    Anticancer activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Anticancer activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    [PMID: 34425478]
    HepG2 IC50
    19.2 μM
    Compound: 5-FU
    Antitumor activity against Homo sapiens (human) HepG2 cells assessed as inhibition of cell viability after 72 hr by MTT assay
    Antitumor activity against Homo sapiens (human) HepG2 cells assessed as inhibition of cell viability after 72 hr by MTT assay
    10.1007/s00044-012-0283-8
    HepG2 IC50
    19.45 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
    [PMID: 24211021]
    HepG2 IC50
    2.1 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells by MTT assay
    Cytotoxicity against human HepG2 cells by MTT assay
    [PMID: 28262527]
    HepG2 EC50
    2.21 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 26883149]
    HepG2 IC50
    2.24 μg/mL
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    [PMID: 29100732]
    HepG2 IC50
    2.5 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay
    [PMID: 31829592]
    HepG2 IC50
    2.7 μM
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells after 3 days by MTT assay
    Cytotoxicity against human HepG2 cells after 3 days by MTT assay
    [PMID: 22000925]
    HepG2 IC50
    2.78 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 21131104]
    HepG2 IC50
    2.88 μM
    Compound: 5-FU
    Antitumor activity against human HepG2 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay
    Antitumor activity against human HepG2 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay
    [PMID: 36324491]
    HepG2 IC50
    2.98 μM
    Compound: 5-Fu
    Antiproliferation activity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    Antiproliferation activity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    [PMID: 34186178]
    HepG2 IC50
    20.1 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 28400238]
    HepG2 IC50
    20.4 μM
    Compound: 5-Fu
    Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
    [PMID: 35092899]
    HepG2 IC50
    205.19 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells assessed as reduction in cell growth after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell growth after 48 hrs by MTT assay
    [PMID: 27422336]
    HepG2 IC50
    21.9 μM
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
    [PMID: 23279864]
    HepG2 IC50
    22.8 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 23490159]
    HepG2 EC50
    23.31 μg/mL
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 21889345]
    HepG2 IC50
    23.6 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 29486954]
    HepG2 IC50
    237 μg/mL
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    [PMID: 29207336]
    HepG2 IC50
    24.96 μM
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
    [PMID: 23685571]
    HepG2 IC50
    25 μg/mL
    Compound: 5FU
    Cytotoxicity against human HepG2 cells after 48 hrs by SRB assay
    Cytotoxicity against human HepG2 cells after 48 hrs by SRB assay
    [PMID: 21115211]
    HepG2 IC50
    25.17 μM
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 27133593]
    HepG2 IC50
    26.98 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 24565905]
    HepG2 IC50
    28.8 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 28756264]
    HepG2 IC50
    29.07 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    [PMID: 28458133]
    HepG2 IC50
    29.1 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    [PMID: 28494251]
    HepG2 IC50
    29.81 μM
    Compound: 5-Fu
    Antitumor activity human HepG2 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    Antitumor activity human HepG2 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    [PMID: 36216031]
    HepG2 IC50
    29.87 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay
    [PMID: 23202484]
    HepG2 IC50
    29.98 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells after 3 days by MTT assay
    Cytotoxicity against human HepG2 cells after 3 days by MTT assay
    [PMID: 24095745]
    HepG2 IC50
    29.98 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 25151580]
    HepG2 IC50
    29.98 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 24378217]
    HepG2 IC50
    29.98 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 23988357]
    HepG2 ED50
    3.3 x 10-2 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human HepG2 cells by MTT assay
    Cytotoxicity against human HepG2 cells by MTT assay
    [PMID: 11908984]
    HepG2 IC50
    3.6 μM
    Compound: Fluorouracil
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay
    [PMID: 31013087]
    HepG2 IC50
    30.48 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells treated for 24 hrs measured after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells treated for 24 hrs measured after 72 hrs by MTT assay
    [PMID: 29037951]
    HepG2 IC50
    30.79 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay
    [PMID: 25841199]
    HepG2 IC50
    30.8 μM
    Compound: 5-Fu
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 30527868]
    HepG2 IC50
    31.7 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    [PMID: 30739827]
    HepG2 IC50
    31.98 μM
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells after 2 days by MTT assay
    Cytotoxicity against human HepG2 cells after 2 days by MTT assay
    [PMID: 25841196]
    HepG2 IC50
    31.98 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 30108826]
    HepG2 IC50
    31.98 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 30092368]
    HepG2 IC50
    32.22 μM
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
    [PMID: 22687745]
    HepG2 IC50
    32.57 μM
    Compound: 5-Fu
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 31877536]
    HepG2 IC50
    32.57 μM
    Compound: 5-Fu
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth after 72 hrs by MTT assay
    [PMID: 31883693]
    HepG2 IC50
    32.6 μM
    Compound: 5-Fu
    Cytotoxic activity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxic activity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay
    [PMID: 27993516]
    HepG2 IC50
    32.6 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells by MTT assay
    Cytotoxicity against human HepG2 cells by MTT assay
    [PMID: 28371676]
    HepG2 IC50
    32.87 μM
    Compound: 5-FU
    Growth inhibition of human HepG2 cells after 24 hrs by MTT assay
    Growth inhibition of human HepG2 cells after 24 hrs by MTT assay
    [PMID: 28011220]
    HepG2 IC50
    33.68 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition by MTT assay
    Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition by MTT assay
    [PMID: 31945642]
    HepG2 IC50
    34 μM
    Compound: 5-fu
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 22304344]
    HepG2 IC50
    35.99 μg/mL
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    [PMID: 26546214]
    HepG2 IC50
    36.1 μM
    Compound: 5-Fu
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hr by CCK-8 assay
    Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hr by CCK-8 assay
    [PMID: 36288556]
    HepG2 IC50
    36.6 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 29305189]
    HepG2 IC50
    36.62 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 30007564]
    HepG2 IC50
    36.74 μM
    Compound: 5-Fu
    Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation by MTT assay
    Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation by MTT assay
    [PMID: 36336316]
    HepG2 IC50
    38.34 μM
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 24953029]
    HepG2 IC50
    39.74 μM
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay
    [PMID: 27400887]
    HepG2 IC50
    4.35 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 24119869]
    HepG2 IC50
    4.8 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
    [PMID: 22727445]
    HepG2 IC50
    40.18 μM
    Compound: 5-Fu
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    10.1039/C5MD00163C
    HepG2 IC50
    40.34 μM
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells assessed as induction of cell death incubated for 2 days by MTT assay
    Cytotoxicity against human HepG2 cells assessed as induction of cell death incubated for 2 days by MTT assay
    [PMID: 26259802]
    HepG2 IC50
    40.34 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay
    [PMID: 27189676]
    HepG2 IC50
    40.34 μM
    Compound: 5-Fu
    Growth inhibition against human HepG2 cells after 48 hrs by MTT assay
    Growth inhibition against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 23999046]
    HepG2 IC50
    40.34 μM
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 23558238]
    HepG2 IC50
    41.62 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay
    [PMID: 26873416]
    HepG2 IC50
    46.31 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 22483608]
    HepG2 IC50
    46.83 μM
    Compound: 5-Fu
    Antiproliferative activity against human HepG2 cells measured after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells measured after 48 hrs by MTT assay
    [PMID: 27287368]
    HepG2 IC50
    46.83 μM
    Compound: Fluorouracil
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 27128180]
    HepG2 IC50
    46.83 μM
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 26363869]
    HepG2 IC50
    46.83 μM
    Compound: Fluorouracil
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 25016234]
    HepG2 IC50
    46.83 μM
    Compound: Fluorouracil
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 22809558]
    HepG2 IC50
    47.97 μM
    Compound: 5-Fu
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    [PMID: 30142612]
    HepG2 IC50
    49.02 μM
    Compound: 5-Fu
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 28110871]
    HepG2 IC50
    49.02 μM
    Compound: 5-Fu
    Antiproliferative activity against human HepG2 cells assessed as cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells assessed as cell viability after 72 hrs by MTT assay
    [PMID: 26922223]
    HepG2 IC50
    49.72 μM
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 26883148]
    HepG2 IC50
    5 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    [PMID: 27987485]
    HepG2 IC50
    5 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells after 72 hrs by SRB assay
    Antiproliferative activity against human HepG2 cells after 72 hrs by SRB assay
    [PMID: 29326016]
    HepG2 IC50
    5 μM
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay
    Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay
    [PMID: 22409771]
    HepG2 IC50
    5.3 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    [PMID: 28623814]
    HepG2 IC50
    5.7 μM
    Compound: 5FU
    Cytotoxicity against human HepG2 cells incubated for 72 hrs by SRB assay
    Cytotoxicity against human HepG2 cells incubated for 72 hrs by SRB assay
    [PMID: 22867707]
    HepG2 IC50
    5.82 μM
    Compound: 5-FU
    Antiproliferative activity in human HepG2 cells after 72 hrs by MTT assay
    Antiproliferative activity in human HepG2 cells after 72 hrs by MTT assay
    10.1039/C6MD00252H
    HepG2 IC50
    5.86 μM
    Compound: 5-Fluorouracil
    Anticancer activity against human HepG2 cells assessed as cell survival after 48 hrs by MTT assay
    Anticancer activity against human HepG2 cells assessed as cell survival after 48 hrs by MTT assay
    [PMID: 25812966]
    HepG2 IC50
    51.5 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 23067549]
    HepG2 EC50
    52.43 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
    [PMID: 20409617]
    HepG2 IC50
    55.2 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay
    [PMID: 26291038]
    HepG2 IC50
    55.74 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    10.1039/C6MD00061D
    HepG2 IC50
    56.2 μM
    Compound: 5-Fluoruracil
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    [PMID: 22555152]
    HepG2 IC50
    59.12 μM
    Compound: 5-Fu
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 29958763]
    HepG2 IC50
    6.6 μM
    Compound: FUra
    Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay
    Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay
    [PMID: 27073055]
    HepG2 IC50
    6.6 μM
    Compound: FUra
    Cytotoxicity against human HepG2 cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay
    [PMID: 27501415]
    HepG2 IC50
    6.69 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    [PMID: 34624825]
    HepG2 IC50
    6.9 μM
    Compound: 5-Fluorouracil
    Antitumor activity against human HepG2 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay
    Antitumor activity against human HepG2 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay
    [PMID: 28926764]
    HepG2 IC50
    60.73 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay
    [PMID: 31401008]
    HepG2 IC50
    63.37 μM
    Compound: 5-Fu
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 30108924]
    HepG2 IC50
    66.42 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by MTT assay
    [PMID: 30826506]
    HepG2 IC50
    66.42 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells by MTT assay
    Cytotoxicity against human HepG2 cells by MTT assay
    [PMID: 33831559]
    HepG2 IC50
    68 μM
    Compound: 5-Fu
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 31057737]
    HepG2 GI50
    7 μM
    Compound: 5-FU
    Hepatotoxicity against human HepG2 cells assessed as growth inhibition measured after 48 hrs by MTT assay
    Hepatotoxicity against human HepG2 cells assessed as growth inhibition measured after 48 hrs by MTT assay
    [PMID: 27688184]
    HepG2 IC50
    7.22 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HepG2 cells by MTT assay
    Antiproliferative activity against human HepG2 cells by MTT assay
    [PMID: 31546197]
    HepG2 IC50
    7.43 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 24286761]
    HepG2 IC50
    7.6 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 24547794]
    HepG2 IC50
    72.33 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
    [PMID: 34838335]
    HepG2 IC50
    76.7 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells after 2 days by alamar blue assay
    Cytotoxicity against human HepG2 cells after 2 days by alamar blue assay
    [PMID: 22093761]
    HepG2 IC50
    76.9 μM
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells assessed as decrease in cell viability by MTT assay
    Cytotoxicity against human HepG2 cells assessed as decrease in cell viability by MTT assay
    [PMID: 29489361]
    HepG2 IC50
    8 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 27343853]
    HepG2 IC50
    8 μM
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
    [PMID: 25969171]
    HepG2 IC50
    8.02 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth by MTT assay
    Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth by MTT assay
    [PMID: 31884408]
    HepG2 IC50
    8.2 ng/mL
    Compound: fluorouracil
    Cytotoxicity against human HepG2 cells by MTT assay
    Cytotoxicity against human HepG2 cells by MTT assay
    [PMID: 22011319]
    HepG2 IC50
    8.6 μg/mL
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay
    [PMID: 22204901]
    HepG2 IC50
    8.6 μg/mL
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 96 hrs
    Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 96 hrs
    [PMID: 29673982]
    HepG2 IC50
    8.6 μg/mL
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells assessed as loss of cell monolayers after 96 hrs
    Cytotoxicity against human HepG2 cells assessed as loss of cell monolayers after 96 hrs
    [PMID: 21130542]
    HepG2 IC50
    8.66 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    [PMID: 36331508]
    HepG2 IC50
    8.69 μM
    Compound: 5-Fu
    Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    [PMID: 32791397]
    HepG2 IC50
    8.8 μM
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 31276896]
    HepG2 IC50
    8.9 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay
    [PMID: 31734024]
    HepG2 IC50
    8.9 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    [PMID: 28525845]
    HepG2 IC50
    8.9 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
    [PMID: 27875779]
    HepG2 IC50
    86.87 μM
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells assessed as growth inhibition by MTT assay
    Cytotoxicity against human HepG2 cells assessed as growth inhibition by MTT assay
    [PMID: 24684840]
    HepG2 IC50
    9.1 μg/mL
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay
    [PMID: 23022735]
    HepG2 IC50
    9.2 μM
    Compound: 5-FU
    Antiproliferative activity against human HepG2 cells after 3 days by MTT assay
    Antiproliferative activity against human HepG2 cells after 3 days by MTT assay
    [PMID: 18424155]
    HepG2 IC50
    9.23 μg/mL
    Compound: 5-Fu
    Cytotoxicity against human HepG2 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human HepG2 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    [PMID: 27262600]
    HepG2 IC50
    9.3 μg/mL
    Compound: 5-FU
    Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
    Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay
    [PMID: 22647218]
    HGC-27 IC50
    > 30 μM
    Compound: 5-FU
    Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    [PMID: 33248852]
    HGC-27 IC50
    11.02 μM
    Compound: 5-FU
    Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay
    [PMID: 28759876]
    HGC-27 IC50
    14.72 μM
    Compound: 5-FU
    Cytotoxicity against human HGC27 cells after 48 hrs by MTT assay
    Cytotoxicity against human HGC27 cells after 48 hrs by MTT assay
    [PMID: 28431881]
    HGC-27 IC50
    18 μM
    Compound: 5-FU
    Cytotoxicity against human HGC27 cells assessed as reduction in cell viability by MTT assay
    Cytotoxicity against human HGC27 cells assessed as reduction in cell viability by MTT assay
    [PMID: 31029946]
    HGC-27 IC50
    27.5 μM
    Compound: 5-Fu
    Cytotoxicity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    [PMID: 34628244]
    HGC-27 IC50
    4.28 μM
    Compound: 5-FU
    Anticancer activity against human HGC-27 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Anticancer activity against human HGC-27 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    [PMID: 31577977]
    HGC-27 IC50
    45.2 μM
    Compound: 5-FU
    Antiproliferative activity against human HGC-27 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Antiproliferative activity against human HGC-27 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    [PMID: 35286954]
    HGC-27 IC50
    5.75 μM
    Compound: 5-Fu
    Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    [PMID: 32682202]
    HGC-27 IC50
    76.62 μM
    Compound: 5-FU
    Cytotoxicity in human HGC-27 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity in human HGC-27 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 35085721]
    HGC-27 IC50
    8.22 μM
    Compound: 5-FU
    Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay
    [PMID: 30108876]
    HGC-27 IC50
    8.22 μM
    Compound: 5-Fu
    Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay
    [PMID: 28456031]
    HL-60 IC50
    > 30 μM
    Compound: 5-FU
    Cytotoxicity against human HL60 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human HL60 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 29133061]
    HL-60 IC50
    0.06 μM
    Compound: 5-FU
    Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
    Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
    [PMID: 22959518]
    HL-60 CC50
    0.07 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HL60 cells after 5 days by MTT assay
    Cytotoxicity against human HL60 cells after 5 days by MTT assay
    [PMID: 20227144]
    HL-60 IC50
    0.16 μM
    Compound: fluorouracil
    Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
    Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
    [PMID: 17291040]
    HL-60 IC50
    1.62 μM
    Compound: 5-FU
    Antiproliferative activity against human HL60 cells after 48 hrs by MTS assay
    Antiproliferative activity against human HL60 cells after 48 hrs by MTS assay
    [PMID: 28152430]
    HL-60 IC50
    10.05 μM
    Compound: 5-Fu
    Growth inhibition against human HL60 cells after 48 hrs by MTT assay
    Growth inhibition against human HL60 cells after 48 hrs by MTT assay
    [PMID: 23999046]
    HL-60 IC50
    10.05 μM
    Compound: 5-Fu
    Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
    Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
    [PMID: 23558238]
    HL-60 IC50
    10.45 μM
    Compound: 5-FU
    Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
    [PMID: 25529742]
    HL-60 IC50
    2.37 μM
    Compound: 5-FU
    Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
    [PMID: 29524728]
    HL-60 IC50
    2.37 μM
    Compound: 5-FU
    Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
    [PMID: 29407983]
    HL-60 IC50
    2.45 μM
    Compound: 5-FU
    Antiproliferative activity against human HL60 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human HL60 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 30921757]
    HL-60 IC50
    2.7 pM
    Compound: 5-FU
    Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
    Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
    [PMID: 21640594]
    HL-60 IC50
    2.8 μM
    Compound: 5-Fu
    Antiproliferative activity against human HL60 cells after 72 hrs by tryphan blue staining based hematocytometric method
    Antiproliferative activity against human HL60 cells after 72 hrs by tryphan blue staining based hematocytometric method
    [PMID: 29131616]
    HL-60 IC50
    21.38 μM
    Compound: 5-FU
    Cytotoxicity against human HL60 cells by MTT assay
    Cytotoxicity against human HL60 cells by MTT assay
    [PMID: 18644718]
    HL-60 IC50
    22.3 μM
    Compound: 5-FU
    Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
    Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
    [PMID: 23867385]
    HL-60 IC50
    22.54 μM
    Compound: FUra
    Antiproliferative activity against human HL60 cells assessed as growth inhibition after 72 hrs by MTT assay
    Antiproliferative activity against human HL60 cells assessed as growth inhibition after 72 hrs by MTT assay
    [PMID: 25644674]
    HL-60 IC50
    25.4 μg/mL
    Compound: 5-FU
    Cytotoxicity against Homo sapiens (human) HL60 cells by MTT assay
    Cytotoxicity against Homo sapiens (human) HL60 cells by MTT assay
    10.1007/s00044-009-9193-9
    HL-60 IC50
    266 μM
    Compound: 5-FU
    Cytotoxicity against Homo sapiens (human) HL60 cells after 96 hr by MTT assay
    Cytotoxicity against Homo sapiens (human) HL60 cells after 96 hr by MTT assay
    10.1007/s00044-011-9778-y
    HL-60 IC50
    266 μM
    Compound: 5-Fu
    Antiproliferative activity against human HL60 cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human HL60 cells after 48 hrs by sulforhodamine B assay
    [PMID: 22424614]
    HL-60 IC50
    27.01 μM
    Compound: 5-FU
    Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
    [PMID: 25164762]
    HL-60 IC50
    27.43 μM
    Compound: 5-Fu
    Antiproliferative activity against human HL60 cells assessed as cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human HL60 cells assessed as cell viability after 72 hrs by MTT assay
    [PMID: 26922223]
    HL-60 IC50
    3.46 μM
    Compound: 5-FU
    Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay
    [PMID: 29635169]
    HL-60 IC50
    3.69 μM
    Compound: 5-FU
    Antiproliferative activity against human HL60 cells treated for 24 hrs measured after 72 hrs by MTT assay
    Antiproliferative activity against human HL60 cells treated for 24 hrs measured after 72 hrs by MTT assay
    [PMID: 29037951]
    HL-60 GI50
    3.8 μM
    Compound: 5-FU
    Antiproliferative activity against human HL60 cells after 3 days by trypan blue staining
    Antiproliferative activity against human HL60 cells after 3 days by trypan blue staining
    [PMID: 18491866]
    HL-60 IC50
    42.8 μM
    Compound: 5-FU
    Cytotoxicity against human HL60 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay
    Cytotoxicity against human HL60 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay
    [PMID: 31253531]
    HL-60 IC50
    5.4 μM
    Compound: 5-FU
    Anticancer activity against Homo sapiens (human) HL60 cells assessed as inhibition of cell proliferation after 72 hr by MTT assay
    Anticancer activity against Homo sapiens (human) HL60 cells assessed as inhibition of cell proliferation after 72 hr by MTT assay
    10.1007/s00044-012-0240-6
    HL-60 IC50
    54.54 μM
    Compound: 5-Fu
    Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
    [PMID: 29958763]
    HL-60 IC50
    65.3 μM
    Compound: 5-FU
    Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
    Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
    [PMID: 19324555]
    HL-60 IC50
    65.3 μM
    Compound: 5-FU
    In vitro inhibitory concentration required against human leukemic HL-60 cell line was determined after 48 hrs of drug exposure using MTT method
    In vitro inhibitory concentration required against human leukemic HL-60 cell line was determined after 48 hrs of drug exposure using MTT method
    [PMID: 15380199]
    HL-60 IC50
    67.2 μM
    Compound: 5-FU
    Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
    [PMID: 29305189]
    HL-60 IC50
    68.3 μM
    Compound: 5-Fu
    Cytotoxicity against human HL60 cells after 48 hrs by CCK-8 assay
    Cytotoxicity against human HL60 cells after 48 hrs by CCK-8 assay
    [PMID: 22244588]
    HL-60 IC50
    81.13 μM
    Compound: 5-FU
    Cytotoxicity in human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity in human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 35085721]
    HL-60 IC50
    9.1 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay
    [PMID: 21381696]
    HL-60 IC50
    9.5 μM
    Compound: 5-fluorouracil
    Cytotoxicity in human HL60 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity in human HL60 cells assessed as cell viability after 48 hrs by MTT assay
    [PMID: 21250700]
    HL-60(TB) GI50
    100 nM
    Compound: 5FU
    Growth inhibition of human HL-60(TB) cells after 48 hrs by SRB assay
    Growth inhibition of human HL-60(TB) cells after 48 hrs by SRB assay
    [PMID: 23094992]
    HL-60(TB) GI50
    100 μM
    Compound: 5-Fu
    Growth inhibition of human HL-60(TB) cells after 48 hrs by SRB assay
    Growth inhibition of human HL-60(TB) cells after 48 hrs by SRB assay
    [PMID: 22512908]
    HL-60(TB) GI50
    2.3 μM
    Compound: 5-FU
    Anticancer activity against human HL-60(TB) cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human HL-60(TB) cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    HL-60(TB) GI50
    2.3 μM
    Compound: 5-FU
    Growth inhibition of human HL-60(TB) cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human HL-60(TB) cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    HL-60(TB) IC50
    85.1 μM
    Compound: 5-Fluorouracil
    Antileukemic activity against human HL-60(TB) cells assessed as inhibition of tumor growth after 24 hrs
    Antileukemic activity against human HL-60(TB) cells assessed as inhibition of tumor growth after 24 hrs
    [PMID: 24657568]
    HOP-62 GI50
    0.39 μM
    Compound: 5-FU
    Anticancer activity against human HOP-62 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human HOP-62 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    HOP-62 GI50
    0.39 μM
    Compound: 5-FU
    Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    HOP-62 GI50
    4.1 μM
    Compound: 5FU
    Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay
    [PMID: 21489802]
    HOP-92 GI50
    77.9 μM
    Compound: 5-FU
    Anticancer activity against human HOP-92 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human HOP-92 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    HOP-92 GI50
    77.9 μM
    Compound: 5-FU
    Growth inhibition of human HOP92 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human HOP92 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    Hs-578T GI50
    9.77 μM
    Compound: 5-FU
    Anticancer activity against human Hs-578T cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human Hs-578T cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    Hs-578T GI50
    9.77 μM
    Compound: 5-FU
    Growth inhibition of human Hs 578T cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human Hs 578T cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    HSC-2 CC50
    > 1000 μM
    Compound: 5-FU
    Cytotoxicity against human HSC-2 cells incubated for 48 hrs by MTT assay
    Cytotoxicity against human HSC-2 cells incubated for 48 hrs by MTT assay
    [PMID: 33744685]
    HSC-2 CC50
    13 μM
    Compound: 5-FU
    Cytotoxicity against human HSC-2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human HSC-2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 32795767]
    HSC-2 CC50
    47 μM
    Compound: 5-FU
    Cytotoxicity against human HSC2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human HSC2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 31532650]
    HSC-3 CC50
    13 μM
    Compound: 5-FU
    Cytotoxicity against human HSC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human HSC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 32795767]
    HSC-4 CC50
    25 μM
    Compound: 5-FU
    Cytotoxicity against human HSC4 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human HSC4 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 31532650]
    HT-1080 EC50
    0.29 μg/mL
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HT1080 cells by MTT assay
    Antiproliferative activity against human HT1080 cells by MTT assay
    [PMID: 12444707]
    HT-1080 ED50
    0.48 μg/mL
    Compound: 5-fluorouracil
    Antiproliferative activity against human HT1080 cells after 4 days by MTT assay
    Antiproliferative activity against human HT1080 cells after 4 days by MTT assay
    [PMID: 11374950]
    HT-1080 EC50
    1.38 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay
    [PMID: 12027739]
    HT-1080 IC50
    1.5 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HT1080 cells assessed as cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human HT1080 cells assessed as cell viability after 72 hrs by MTT assay
    [PMID: 11575942]
    HT-1080 IC50
    15.2 μM
    Compound: 5-FU
    Cytotoxicity against human HT1080 cells after 48 hrs by MTT assay
    Cytotoxicity against human HT1080 cells after 48 hrs by MTT assay
    [PMID: 23067549]
    HT-1080 IC50
    3.06 μM
    Compound: 5-Fu
    Cytotoxicity against human HT1080 cells by MTT assay
    Cytotoxicity against human HT1080 cells by MTT assay
    [PMID: 22801644]
    HT-1080 IC50
    35.62 μM
    Compound: 5-Fu
    Growth inhibition against human HT1080 cells after 48 hrs by MTT assay
    Growth inhibition against human HT1080 cells after 48 hrs by MTT assay
    [PMID: 23999046]
    HT-1080 IC50
    35.62 μM
    Compound: 5-Fu
    Cytotoxicity against human HT1080 cells after 48 hrs by MTT assay
    Cytotoxicity against human HT1080 cells after 48 hrs by MTT assay
    [PMID: 23558238]
    HT-1080 IC50
    3700 nM
    Compound: 5-fluorouracil
    Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay
    [PMID: 14640513]
    HT-1080 IC50
    5.2 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
    Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
    [PMID: 19919052]
    HT-1080 IC50
    70.8 μM
    Compound: 5-Fu
    Cytotoxicity against human HT1080 cells assessed as growth inhibition after 24 hrs by MTT assay
    Cytotoxicity against human HT1080 cells assessed as growth inhibition after 24 hrs by MTT assay
    [PMID: 23647462]
    HT-1080 ED50
    8 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HT1080 cells by MTT assay
    Cytotoxicity against human HT1080 cells by MTT assay
    [PMID: 11430002]
    HT-1080 ED50
    8 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human HT1080 cells by MTT assay
    Antiproliferative activity against human HT1080 cells by MTT assay
    [PMID: 11325233]
    HT-1080 ED50
    8 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human HT1080 cells by MTT assay
    Antiproliferative activity against human HT1080 cells by MTT assay
    [PMID: 11277741]
    HT-1080 ED50
    8 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HT1080 cells by 3-(4,5-dimethylthiazol-2-yl)-2,5-dimethyltetrazolium bromide assay
    Cytotoxicity against human HT1080 cells by 3-(4,5-dimethylthiazol-2-yl)-2,5-dimethyltetrazolium bromide assay
    [PMID: 11141109]
    HT-1080 IC50
    8.58 μM
    Compound: 5-Fluoro uracil
    Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
    Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
    [PMID: 19689125]
    HT-1080 IC50
    9.45 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
    Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay
    [PMID: 18440233]
    HT-22 CC50
    8.1 μM
    Compound: 5-Fu
    Cytotoxicity against mouse HT22 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against mouse HT22 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 32832031]
    HT-29 IC50
    > 10 μM
    Compound: 5-FU
    Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 32127259]
    HT-29 IC50
    > 100 μM
    Compound: 5-Fu
    Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay
    10.1039/C5MD00163C
    HT-29 IC50
    > 100 μM
    Compound: 5-FU
    Cytotoxicity in human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity in human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 35085721]
    HT-29 CC50
    > 2512 μM
    Compound: 5-Fu
    Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay
    [PMID: 26727215]
    HT-29 IC50
    > 50 μM
    Compound: 5-FU
    Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 24 hrs by MTT assay
    Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 24 hrs by MTT assay
    [PMID: 26922233]
    HT-29 GI50
    0.17 μM
    Compound: 5-FU
    Anticancer activity against human HT-29 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human HT-29 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    HT-29 GI50
    0.17 μM
    Compound: 5-FU
    Growth inhibition of human HT-29 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human HT-29 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    HT-29 ED50
    0.2 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human HT-29 cells by MTT assay
    Cytotoxicity against human HT-29 cells by MTT assay
    [PMID: 16309328]
    HT-29 GI50
    0.4 μg/mL
    Compound: 5FU
    Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by SRB assay method
    Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by SRB assay method
    [PMID: 26383125]
    HT-29 IC50
    0.6 μM
    Compound: 5-Fu
    Cytotoxicity against human HT29 cells by MTT assay
    Cytotoxicity against human HT29 cells by MTT assay
    [PMID: 18606546]
    HT-29 IC50
    0.6 μM
    Compound: 5-Fu
    Cytotoxicity against human HT29 cells by MTT microassay
    Cytotoxicity against human HT29 cells by MTT microassay
    [PMID: 17320246]
    HT-29 IC50
    1.08 μM
    Compound: 5-FU
    Cytotoxicity against human HT-29 cells after 6 days by SRB colorimetric assay
    Cytotoxicity against human HT-29 cells after 6 days by SRB colorimetric assay
    [PMID: 21684047]
    HT-29 IC50
    10.26 μg/mL
    Compound: 5-FU
    Cytotoxicity against Homo sapiens (human) HT-29 cells by MTT assay
    Cytotoxicity against Homo sapiens (human) HT-29 cells by MTT assay
    10.1007/s00044-009-9193-9
    HT-29 IC50
    12.2 μM
    Compound: 5-FU
    Antitumor activity against human HT-29 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    Antitumor activity against human HT-29 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    [PMID: 35777102]
    HT-29 GI50
    12.6 μM
    Compound: 5-Fu
    Antiproliferative activity against human HT-29 cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells incubated for 48 hrs by MTT assay
    [PMID: 32832031]
    HT-29 IC50
    12.67 μM
    Compound: 5-Fu
    Antiproliferative activity against human HT-29 cells assessed as cell growth inhibition incubated for 4 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells assessed as cell growth inhibition incubated for 4 hrs by MTT assay
    [PMID: 32992255]
    HT-29 IC50
    13.37 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HT-29 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay
    [PMID: 32387836]
    HT-29 IC50
    14.8 μM
    Compound: 5-Fu
    Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay
    [PMID: 26727215]
    HT-29 IC50
    14.9 μM
    Compound: 1; 5-FU
    Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
    Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay
    [PMID: 33819035]
    HT-29 IC50
    146.2 μM
    Compound: 5-FU
    Cytotoxicity in human HT-29 cells assessed as growth inhibition incubated for 24 hrs by MTT assay
    Cytotoxicity in human HT-29 cells assessed as growth inhibition incubated for 24 hrs by MTT assay
    [PMID: 31128448]
    HT-29 IC50
    15.83 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by WST-1 assay
    Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by WST-1 assay
    [PMID: 26413725]
    HT-29 IC50
    15.96 μM
    Compound: 5-FU
    Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay
    [PMID: 35290844]
    HT-29 IC50
    16.07 μM
    Compound: 5-FU
    Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability by MTT assay
    Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability by MTT assay
    [PMID: 34157389]
    HT-29 IC50
    17.2 μM
    Compound: 5-Fu
    Cytotoxicity against human HT-29 cells after 2 days by MTT assay
    Cytotoxicity against human HT-29 cells after 2 days by MTT assay
    [PMID: 24767839]
    HT-29 IC50
    17.48 μM
    Compound: 5-FU
    Anticancer activity against human HT-29 cells assessed as inhibition of cell proliferation by MTT assay
    Anticancer activity against human HT-29 cells assessed as inhibition of cell proliferation by MTT assay
    [PMID: 36439975]
    HT-29 IC50
    18.77 nM
    Compound: 5-FU
    Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 36269639]
    HT-29 IC50
    2.42 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 31546197]
    HT-29 IC50
    2.58 μM
    Compound: 5-Fu
    Cytotoxicity against human HT-29 cells after 3 days by SRB assay
    Cytotoxicity against human HT-29 cells after 3 days by SRB assay
    [PMID: 24704691]
    HT-29 IC50
    2.8 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay
    [PMID: 27092413]
    HT-29 IC50
    22.23 μM
    Compound: 5-Fu
    Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay
    [PMID: 29958763]
    HT-29 IC50
    23.9 μM
    Compound: 5-FU
    Cytotoxicity against human HT-29 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
    Cytotoxicity against human HT-29 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
    [PMID: 35635947]
    HT-29 IC50
    24.5 μM
    Compound: 5-FU
    Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay
    Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay
    [PMID: 26703795]
    HT-29 IC50
    24.5 μM
    Compound: 5-FU
    Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay
    [PMID: 23665106]
    HT-29 IC50
    24.87 μM
    Compound: 5-Fu
    Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay
    Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay
    [PMID: 24583355]
    HT-29 IC50
    25 μM
    Compound: 5-FU
    Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
    Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
    [PMID: 26922233]
    HT-29 IC50
    25.08 μM
    Compound: FUra
    Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 72 hrs by SRB method
    Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 72 hrs by SRB method
    [PMID: 25644674]
    HT-29 IC50
    25.9 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human HT-29 cells cultured as 3D spheroids assessed as inhibition of spheroid formation measured after 48 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells cultured as 3D spheroids assessed as inhibition of spheroid formation measured after 48 hrs by MTT assay
    [PMID: 33872002]
    HT-29 IC50
    3.24 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against Homo sapiens (human) HT-29 cells assessed as inhibition of cell growth after 48 hr by MTT assay
    Cytotoxicity against Homo sapiens (human) HT-29 cells assessed as inhibition of cell growth after 48 hr by MTT assay
    10.1007/s00044-012-0209-5
    HT-29 IC50
    4.6 μM
    Compound: 5-Fluorouracil
    Antitumor activity against human HT-29 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay
    Antitumor activity against human HT-29 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay
    [PMID: 28926764]
    HT-29 IC50
    4.9 μM
    Compound: 5-FU
    Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay
    [PMID: 28494251]
    HT-29 IC50
    5.2 μM
    Compound: 1; 5-FU
    Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 48 hrs in presence of 5 mM GSH by SRB assay
    Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 48 hrs in presence of 5 mM GSH by SRB assay
    [PMID: 33819035]
    HT-29 IC50
    5.3 μM
    Compound: 5-FU
    Antiproliferative activity against human HT-29 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay
    Antiproliferative activity against human HT-29 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay
    [PMID: 26731300]
    HT-29 IC50
    5.31 μM
    Compound: 5-FU
    Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
    [PMID: 36923920]
    HT-29 IC50
    540 μM
    Compound: 5-FU
    Cytotoxicity against HT29 cells after 48 hrs by MTT assay
    Cytotoxicity against HT29 cells after 48 hrs by MTT assay
    [PMID: 17604394]
    HT-29 IC50
    6.3 μM
    Compound: 5-FU
    Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
    Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
    [PMID: 26922233]
    HT-29 IC50
    6.35 μM
    Compound: 5-FU
    Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23644215]
    HT-29 IC50
    6.5 μM
    Compound: 5-FU
    Antiproliferative activity against human HT-29 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    [PMID: 30368201]
    HT-29 IC50
    690 nM
    Compound: Fluorouracil
    Antiproliferative activity against human HT-29 cells after 96 hrs by MTT assay
    Antiproliferative activity against human HT-29 cells after 96 hrs by MTT assay
    [PMID: 2778449]
    HT-29 IC50
    7.2 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HT-29 cells incubated for 72 hrs by alamar blue assay
    Cytotoxicity against human HT-29 cells incubated for 72 hrs by alamar blue assay
    [PMID: 28648460]
    HT-29 IC50
    7.3 μM
    Compound: 5-FU
    Cytotoxicity against human HT-29 cells after 72 hrs by crystal violet staining
    Cytotoxicity against human HT-29 cells after 72 hrs by crystal violet staining
    [PMID: 22959205]
    HT-29 IC50
    7.3 μM
    Compound: 5-FU
    Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 144 hrs by crystal violet staining method
    Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 144 hrs by crystal violet staining method
    [PMID: 22450132]
    HT-29 IC50
    7.3 μM
    Compound: 5-FU
    Antiproliferative activity against human HT-29 cells after 72 hrs by crystal violet staining method
    Antiproliferative activity against human HT-29 cells after 72 hrs by crystal violet staining method
    [PMID: 22765897]
    HT-29 ED50
    7.4 x 10-2 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human HT-29 cells by MTT assay
    Cytotoxicity against human HT-29 cells by MTT assay
    [PMID: 11908984]
    HT-29 ED50
    7.7 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HT-29 cells by Alamar blue assay
    Cytotoxicity against human HT-29 cells by Alamar blue assay
    [PMID: 24128077]
    HT-29 IC50
    8.3 μM
    Compound: 5-FU
    Cytotoxicity against human HT-29 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human HT-29 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 29133061]
    HT-29 GI50
    8.9 μM
    Compound: 5FU
    Cytotoxicity against human HT29 cells after 48 hrs
    Cytotoxicity against human HT29 cells after 48 hrs
    [PMID: 18798609]
    HT-29 IC50
    9.72 μM
    Compound: 5-Fu
    Cytotoxicity against Homo sapiens (human) HT-29 cells after 72 hr by MTT assay
    Cytotoxicity against Homo sapiens (human) HT-29 cells after 72 hr by MTT assay
    10.1007/s00044-011-9549-9
    HT-29 IC50
    9.99 μM
    Compound: 5-FU
    Cytotoxicity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTS assay
    Cytotoxicity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTS assay
    [PMID: 30472605]
    hTERT-BJ IC50
    5.5 μM
    Compound: 5-Fluorouracil
    Cytotoxicity activity against human hTERT-BJ cells by MTT assay
    Cytotoxicity activity against human hTERT-BJ cells by MTT assay
    [PMID: 31546197]
    hTERT-BJ GI50
    5.5 μM
    Compound: 5-FU
    Cytotoxicity against human hTERT-BJ cells assessed as growth inhibition after 48 hrs by SRB assay
    Cytotoxicity against human hTERT-BJ cells assessed as growth inhibition after 48 hrs by SRB assay
    [PMID: 31376562]
    hTERT-BJ GI50
    5.5 μM
    Compound: 5-FU
    Antiproliferative activity against human hTERT-BJ cells after 48 hrs by SRB assay
    Antiproliferative activity against human hTERT-BJ cells after 48 hrs by SRB assay
    [PMID: 28728108]
    Huh-7 IC50
    > 100 μM
    Compound: 5-FU
    Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by MTT assay
    [PMID: 26320625]
    Huh-7 IC50
    1.06 μM
    Compound: 5-FU
    Anticancer activity against human Huh-7 cells assessed as inhibition of cell proliferation by MTT assay
    Anticancer activity against human Huh-7 cells assessed as inhibition of cell proliferation by MTT assay
    [PMID: 36439975]
    Huh-7 IC50
    10.41 μg/mL
    Compound: 5-FU
    Cytotoxicity against human HuH7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    Cytotoxicity against human HuH7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    [PMID: 26546214]
    Huh-7 IC50
    15.85 μM
    Compound: 5-Fu
    Growth inhibition of human HuH7 cells after 48 hrs by MTT assay
    Growth inhibition of human HuH7 cells after 48 hrs by MTT assay
    [PMID: 23353737]
    Huh-7 IC50
    2.98 mM
    Compound: 5-FU
    Antiproliferative activity against human HuH7 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay
    Antiproliferative activity against human HuH7 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay
    [PMID: 28073674]
    Huh-7 IC50
    20.03 μg/mL
    Compound: 5-F
    Cytotoxicity against human HuH7 cells after 48 hrs by MTT assay
    Cytotoxicity against human HuH7 cells after 48 hrs by MTT assay
    [PMID: 24342667]
    Huh-7 IC50
    21 μM
    Compound: 5-FU
    Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay
    Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay
    [PMID: 30108969]
    Huh-7 IC50
    21 μM
    Compound: 5-FU
    Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by SRB assay
    Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by SRB assay
    [PMID: 28219046]
    Huh-7 IC50
    30 μM
    Compound: 5-FU
    Antiproliferative activity against human HuH7 cells after 72 hrs by SRB assay
    Antiproliferative activity against human HuH7 cells after 72 hrs by SRB assay
    [PMID: 29326016]
    Huh-7 IC50
    30.3 μM
    Compound: 5-Fu
    Antiproliferative activity against human Huh-7 cells assessed as reduction in cell viability after 48 hr by CCK-8 assay
    Antiproliferative activity against human Huh-7 cells assessed as reduction in cell viability after 48 hr by CCK-8 assay
    [PMID: 36288556]
    Huh-7 IC50
    30.7 μM
    Compound: 5-FU
    Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay
    Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay
    [PMID: 25462277]
    Huh-7 IC50
    30.7 μM
    Compound: 5FU
    Cytotoxicity against human HuH7 cells incubated for 72 hrs by SRB assay
    Cytotoxicity against human HuH7 cells incubated for 72 hrs by SRB assay
    [PMID: 22867707]
    Huh-7 IC50
    30.7 μM
    Compound: 5-Fu
    Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay
    Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay
    [PMID: 22409771]
    Huh-7 IC50
    30.7 μM
    Compound: 5FU
    Cytotoxicity against human HuH7 cells assessed as inhibition of cell proliferation by sulforhodamine B assay
    Cytotoxicity against human HuH7 cells assessed as inhibition of cell proliferation by sulforhodamine B assay
    10.1039/C4MD00306C
    Huh-7 IC50
    390 μM
    Compound: 5-FU
    Cytotoxicity against human HuH7 cells assessed as reduction in cell growth after 48 hrs by MTT assay
    Cytotoxicity against human HuH7 cells assessed as reduction in cell growth after 48 hrs by MTT assay
    [PMID: 27422336]
    Huh-7 IC50
    5.63 μM
    Compound: 5-FU
    Antiproliferative activity against human HuH7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human HuH7 cells after 72 hrs by MTT assay
    [PMID: 29316536]
    HuTu80 GI50
    0.4 μg/mL
    Compound: 5FU
    Cytotoxicity against human HuTu 80 cells assessed as growth inhibition after 48 hrs by SRB assay method
    Cytotoxicity against human HuTu 80 cells assessed as growth inhibition after 48 hrs by SRB assay method
    [PMID: 26383125]
    HuTu80 IC50
    65.2 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HuTu80 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay
    Cytotoxicity against human HuTu80 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay
    [PMID: 36970146]
    HUVEC IC50
    > 200 μM
    Compound: 5-FLU
    Cytotoxicity against HUVEC assessed as reduction in cell viability measured after 24 hrs by MTT assay
    Cytotoxicity against HUVEC assessed as reduction in cell viability measured after 24 hrs by MTT assay
    [PMID: 34606997]
    HUVEC IC50
    24.12 μM
    Compound: 5-Fu
    Cytotoxicity against HUVEC after 48 hrs by MTT assay
    Cytotoxicity against HUVEC after 48 hrs by MTT assay
    [PMID: 24953029]
    HUVEC GI50
    3.6 nM
    Compound: 5FU
    Growth inhibition of human HUVEC cells after 48 hrs by SRB assay
    Growth inhibition of human HUVEC cells after 48 hrs by SRB assay
    [PMID: 23094992]
    HUVEC IC50
    56 μM
    Compound: 5-FU
    Cytotoxicity in HUVEC cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity in HUVEC cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 28754470]
    HUVEC IC50
    56 μM
    Compound: 5-FU
    Cytotoxicity against human HUVEC cells after 48 hrs by MTT assay
    Cytotoxicity against human HUVEC cells after 48 hrs by MTT assay
    [PMID: 25151580]
    HUVEC IC50
    56 μM
    Compound: 5-FU
    Cytotoxicity against human HUVEC after 48 hrs by MTT assay
    Cytotoxicity against human HUVEC after 48 hrs by MTT assay
    [PMID: 24378217]
    HUVEC IC50
    56.37 μM
    Compound: 5-Fu
    Cytotoxicity against human HUVEC cells after 2 days by MTT assay
    Cytotoxicity against human HUVEC cells after 2 days by MTT assay
    [PMID: 25841196]
    HUVEC IC50
    79.6 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against HUVEC assessed as cell growth inhibition by MTT assay
    Cytotoxicity against HUVEC assessed as cell growth inhibition by MTT assay
    [PMID: 27720296]
    HUVEC GI50
    9.72 μM
    Compound: 5-Fu
    Growth inhibition of HUVEC cells after 48 hrs by SRB assay
    Growth inhibition of HUVEC cells after 48 hrs by SRB assay
    [PMID: 22512908]
    HUVEC IC50
    96 μM
    Compound: 5-FLU
    Cytotoxicity against HUVEC assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Cytotoxicity against HUVEC assessed as reduction in cell viability measured after 72 hrs by MTT assay
    [PMID: 34606997]
    IEC-6 IC50
    0.66 μM
    Compound: 5-FU
    Cytotoxicity against rat IEC-6 cells after 6 days by SRB colorimetric assay
    Cytotoxicity against rat IEC-6 cells after 6 days by SRB colorimetric assay
    [PMID: 21684047]
    IGROV-1 GI50
    1.22 μM
    Compound: 5-FU
    Anticancer activity against human IGROV-1 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human IGROV-1 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    IGROV-1 GI50
    1.22 μM
    Compound: 5-FU
    Growth inhibition of human IGROV1 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human IGROV1 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    IGROV-1 IC50
    10.6 μM
    Compound: 5FU
    Cytotoxicity against human IGROV1 cells after 72 hrs
    Cytotoxicity against human IGROV1 cells after 72 hrs
    [PMID: 30035541]
    IGROV-1 GI50
    8.12 nM
    Compound: 5FU
    Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay
    Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay
    [PMID: 23094992]
    IGROV-1 GI50
    9.1 μM
    Compound: 5-Fu
    Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay
    Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay
    [PMID: 22512908]
    IMR-32 IC50
    1.3 μM
    Compound: 5-FU
    Cytotoxicity against human IMR32 cells after 48 hrs by SRB assay
    Cytotoxicity against human IMR32 cells after 48 hrs by SRB assay
    [PMID: 25176329]
    IMR-32 IC50
    1.3 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human IMR32 cells after 48 hrs by SRB assay
    Cytotoxicity against human IMR32 cells after 48 hrs by SRB assay
    [PMID: 24056146]
    IMR-32 IC50
    18 μM
    Compound: 5-fluorouracil
    Anticancer activity against human IMR32 cells assessed as cell viability after 48 hrs by SRB assay
    Anticancer activity against human IMR32 cells assessed as cell viability after 48 hrs by SRB assay
    [PMID: 21074444]
    IMR-32 IC50
    5.7 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human IMR32 cells after 48 hrs by CellTiter-Glo assay
    Cytotoxicity against human IMR32 cells after 48 hrs by CellTiter-Glo assay
    [PMID: 31999116]
    IMR-90 IC50
    136.4 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human IMR90 cells assessed as cell growth inhibition by MTT assay
    Cytotoxicity against human IMR90 cells assessed as cell growth inhibition by MTT assay
    [PMID: 26629861]
    Jurkat IC50
    87 μM
    Compound: 5-FU
    Antiproliferative activity against human p53 deficient Jurkat cells after 72 hrs by celltiter-glo assay
    Antiproliferative activity against human p53 deficient Jurkat cells after 72 hrs by celltiter-glo assay
    [PMID: 20873740]
    Jurkat IC50
    87.73 μM
    Compound: 5-FU
    Antiproliferative activity against p53 deficient human Jurkat cells after 72 hrs by proliferative assay
    Antiproliferative activity against p53 deficient human Jurkat cells after 72 hrs by proliferative assay
    [PMID: 18469809]
    K562 IC50
    > 100 μM
    Compound: 5-FU
    Antiproliferative activity against human p53 deficient K562 cells after 72 hrs by celltiter-glo assay
    Antiproliferative activity against human p53 deficient K562 cells after 72 hrs by celltiter-glo assay
    [PMID: 20873740]
    K562 IC50
    > 100 μM
    Compound: 5-FU
    Cytotoxicity against human K562 cells after 48 hrs by MTT assay
    Cytotoxicity against human K562 cells after 48 hrs by MTT assay
    [PMID: 19324555]
    K562 IC50
    > 100 μM
    Compound: 5-FU
    Antiproliferative activity against p53 deficient human K562 cells after 72 hrs
    Antiproliferative activity against p53 deficient human K562 cells after 72 hrs
    [PMID: 18469809]
    K562 GI50
    0.9 μg/mL
    Compound: 5FU
    Cytotoxicity against human K562 cells assessed as growth inhibition after 48 hrs by SRB assay method
    Cytotoxicity against human K562 cells assessed as growth inhibition after 48 hrs by SRB assay method
    [PMID: 26383125]
    K562 IC50
    114.5 μM
    Compound: 5-Fu
    Cytotoxicity against human K562 cells after 48 hrs by MTT assay
    Cytotoxicity against human K562 cells after 48 hrs by MTT assay
    [PMID: 23356786]
    K562 IC50
    12.21 μM
    Compound: 5-FU
    Cytotoxicity against human K562 cells after 72 hrs by MTT assay
    Cytotoxicity against human K562 cells after 72 hrs by MTT assay
    [PMID: 30677614]
    K562 IC50
    126 μM
    Compound: 5-Fluorouracil
    Antileukemic activity against human K562 cells assessed as inhibition of tumor growth after 24 hrs
    Antileukemic activity against human K562 cells assessed as inhibition of tumor growth after 24 hrs
    [PMID: 24657568]
    K562 ED50
    16.22 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human K562 cells after 6 hrs by Alamar Blue assay
    Cytotoxicity against human K562 cells after 6 hrs by Alamar Blue assay
    [PMID: 24020806]
    K562 GI50
    16.7 μM
    Compound: 5FU
    Cytotoxicity against human K562 cells after 48 hrs
    Cytotoxicity against human K562 cells after 48 hrs
    [PMID: 18798609]
    K562 GI50
    18.5 μM
    Compound: 5-FU
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    [PMID: 29040954]
    K562 GI50
    19 μM
    Compound: 5-Fu
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    [PMID: 28763647]
    K562 IC50
    2.1 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human K562 cells after 48 hrs by MTT assay
    Cytotoxicity against human K562 cells after 48 hrs by MTT assay
    [PMID: 22537362]
    K562 IC50
    20.21 μM
    Compound: 5-FU
    Cytotoxicity against human K562 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    Cytotoxicity against human K562 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    [PMID: 33740546]
    K562 IC50
    20.7 μM
    Compound: 5-Fu
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    Antiproliferative activity against human K562 cells after 48 hrs by MTT assay
    [PMID: 30737134]
    K562 ED50
    21 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human K562 cells by Alamar blue assay
    Cytotoxicity against human K562 cells by Alamar blue assay
    [PMID: 24128077]
    K562 IC50
    23.55 μM
    Compound: 5-Fu
    Growth inhibition against human K562 cells after 48 hrs by MTT assay
    Growth inhibition against human K562 cells after 48 hrs by MTT assay
    [PMID: 23999046]
    K562 IC50
    23.55 μM
    Compound: 5-Fu
    Cytotoxicity against human K562 cells after 48 hrs by MTT assay
    Cytotoxicity against human K562 cells after 48 hrs by MTT assay
    [PMID: 23558238]
    K562 IC50
    28 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human K562 cells after 72 hrs by MTT assay
    Cytotoxicity against human K562 cells after 72 hrs by MTT assay
    [PMID: 23535322]
    K562 IC50
    3.54 μM
    Compound: 5-Fu
    Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
    Antiproliferative activity against human K562 cells after 72 hrs by MTT assay
    [PMID: 28165738]
    K562 GI50
    3.58 μM
    Compound: 5-FU
    Anticancer activity against human K562 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human K562 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    K562 GI50
    3.58 μM
    Compound: 5-FU
    Growth inhibition of human K562 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human K562 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    K562 IC50
    3.86 μM
    Compound: 5-FU
    Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 30921757]
    K562 IC50
    3.94 μM
    Compound: 5-Fu
    Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 31877536]
    K562 IC50
    3.94 μM
    Compound: 5-Fu
    Antiproliferative activity against human K562 cells assessed as reduction in cell growth after 72 hrs by MTT assay
    Antiproliferative activity against human K562 cells assessed as reduction in cell growth after 72 hrs by MTT assay
    [PMID: 31883693]
    K562 IC50
    30.5 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human K562 cells incubated for 72 hrs by alamar blue assay
    Cytotoxicity against human K562 cells incubated for 72 hrs by alamar blue assay
    [PMID: 28648460]
    K562 IC50
    31.6 μM
    Compound: 5-Fu
    Anticancer activity against human K562 cells after 48 hrs by MTT assay
    Anticancer activity against human K562 cells after 48 hrs by MTT assay
    [PMID: 25462264]
    K562 IC50
    32.92 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human K562 cells by disk diffusion soft agar colony formation assay
    Cytotoxicity against human K562 cells by disk diffusion soft agar colony formation assay
    [PMID: 31117520]
    K562 IC50
    38 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human K562 cells after 48 hrs by MTT assay
    Cytotoxicity against human K562 cells after 48 hrs by MTT assay
    [PMID: 21131104]
    K562 IC50
    38.58 μM
    Compound: 5-FU
    Growth inhibition of human K562 cells after 48 hrs by WST1 assay
    Growth inhibition of human K562 cells after 48 hrs by WST1 assay
    [PMID: 28126436]
    K562 IC50
    38.6 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human K562 cells by MTT reduction assay
    Antiproliferative activity against human K562 cells by MTT reduction assay
    [PMID: 33421712]
    K562 IC50
    4.02 μM
    Compound: 5-Fu
    Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 31202992]
    K562 IC50
    41.66 μM
    Compound: 5-FU
    Cytotoxicity against human K562 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human K562 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 31673307]
    K562 IC50
    45.4 μM
    Compound: 5-FU
    Cytotoxicity against human K562 cells after 72 hrs by MTT assay
    Cytotoxicity against human K562 cells after 72 hrs by MTT assay
    [PMID: 20494492]
    K562 IC50
    45.4 μM
    Compound: 5-FU
    Cytotoxicity against Homo sapiens (human) K562 cells by MTT assay
    Cytotoxicity against Homo sapiens (human) K562 cells by MTT assay
    10.1007/s00044-010-9395-1
    K562 IC50
    8.48 μg/mL
    Compound: 5-FU
    Anti-leukemia activity in human K562 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
    Anti-leukemia activity in human K562 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay
    [PMID: 30114660]
    K562 IC50
    9.49 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 29133049]
    K562/Adr IC50
    31.9 μM
    Compound: 5-FU
    Cytotoxicity against human K562/ADR cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human K562/ADR cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 31673307]
    KATO III stomach cancer cell line EC50
    21.4 μM
    Compound: 5FU
    Cytotoxicity against human KATO III stomach cancer cell line assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay
    Cytotoxicity against human KATO III stomach cancer cell line assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay
    [PMID: 35939803]
    KB IC50
    > 10 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human KB cells after 2 to 7 days by neutral red assay
    Cytotoxicity against human KB cells after 2 to 7 days by neutral red assay
    [PMID: 11374943]
    KB IC50
    1.23 μM
    Compound: 5-Fu
    Cytotoxicity against human KB cells after 48 hrs by MTT assay
    Cytotoxicity against human KB cells after 48 hrs by MTT assay
    [PMID: 24953029]
    KB ED50
    1.25 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human KB cells after 3 days by trypan blue exclusion technique
    Cytotoxicity against human KB cells after 3 days by trypan blue exclusion technique
    [PMID: 1800632]
    KB IC50
    11.9 μM
    Compound: 5-FU
    Cytotoxicity against human KB cells after 3 days by MTT assay
    Cytotoxicity against human KB cells after 3 days by MTT assay
    [PMID: 21144621]
    KB IC50
    12.5 μM
    Compound: Fluorouracil
    Cytotoxicity against human KB cells after 3 days by MTT assay
    Cytotoxicity against human KB cells after 3 days by MTT assay
    [PMID: 21843939]
    KB IC50
    12.5 μM
    Compound: fluorouracil
    Cytotoxicity against human KB cells after 72 hrs MTT assay
    Cytotoxicity against human KB cells after 72 hrs MTT assay
    [PMID: 19846302]
    KB IC50
    13.4 μM
    Compound: 5-fu
    Cytotoxicity against human KB cells after 48 hrs
    Cytotoxicity against human KB cells after 48 hrs
    [PMID: 17000031]
    KB IC50
    15.9 μM
    Compound: Flurouracil
    Cytotoxicity against human KB cells after 72 hrs by MTT assay
    Cytotoxicity against human KB cells after 72 hrs by MTT assay
    [PMID: 21273072]
    KB IC50
    2.16 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human KB cells after 48 hrs by MTT assay
    Cytotoxicity against human KB cells after 48 hrs by MTT assay
    [PMID: 21131104]
    KB IC50
    4.46 nM
    Compound: Fluorouracil
    Cytotoxicity against human KB cells by MTT assay
    Cytotoxicity against human KB cells by MTT assay
    [PMID: 19345581]
    KB IC50
    4.46 μM
    Compound: Fluorouracil
    Cytotoxicity against human KB cells after 3 days by MTT assay
    Cytotoxicity against human KB cells after 3 days by MTT assay
    [PMID: 20356655]
    KB IC50
    4.84 μM
    Compound: FUra
    Cytotoxicity against human KB cells after 72 hrs by SRB assay
    Cytotoxicity against human KB cells after 72 hrs by SRB assay
    [PMID: 27073055]
    KB IC50
    4.84 μM
    Compound: FUra
    Cytotoxicity against human KB cells after 72 hrs by SRB assay
    Cytotoxicity against human KB cells after 72 hrs by SRB assay
    [PMID: 23867603]
    KB IC50
    4.84 μM
    Compound: FUra
    Cytotoxicity against human KB cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay
    Cytotoxicity against human KB cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay
    [PMID: 27501415]
    KB GI50
    5.2 μM
    Compound: 5FU
    Growth inhibition of human KB cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human KB cells after 48 hrs by sulforhodamine B assay
    [PMID: 21489802]
    KB IC50
    53.52 μM
    Compound: 5-FU
    Antiproliferative activity against human KB cells after 48 hrs by MTT assay
    Antiproliferative activity against human KB cells after 48 hrs by MTT assay
    [PMID: 25164762]
    KB IC50
    6.8 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human KB cells after 48 hrs by MTT assay
    Cytotoxicity against human KB cells after 48 hrs by MTT assay
    [PMID: 22537362]
    KB IC50
    7.7 pM
    Compound: 5-FU
    Cytotoxicity against human KB cells after 72 hrs by MTT assay
    Cytotoxicity against human KB cells after 72 hrs by MTT assay
    [PMID: 21640594]
    KB IC50
    8.1 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human KB cells after 4 days by MTT assay
    Cytotoxicity against human KB cells after 4 days by MTT assay
    [PMID: 24359303]
    KB IC50
    8.28 μM
    Compound: 5-FU
    Cytotoxicity against human KB cells after 72 hrs by MTT assay
    Cytotoxicity against human KB cells after 72 hrs by MTT assay
    [PMID: 22749192]
    KB IC50
    9 μM
    Compound: Fluorouracil
    Cytotoxicity against human KB cells after 72 hrs ny MTT assay
    Cytotoxicity against human KB cells after 72 hrs ny MTT assay
    [PMID: 22200404]
    KB IC50
    9.85 μM
    Compound: 5-FU
    Antiproliferative activity against human KB cells after 72 hrs by MTT assay
    Antiproliferative activity against human KB cells after 72 hrs by MTT assay
    [PMID: 22079378]
    KCL-22 IC50
    3.52 μM
    Compound: FU
    Antiproliferative activity against human KCL22 cells after 48 hrs by MTT assay
    Antiproliferative activity against human KCL22 cells after 48 hrs by MTT assay
    [PMID: 24941129]
    KG-1 IC50
    82.97 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
    Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay
    [PMID: 27322756]
    KM12 CC50
    > 2512 μM
    Compound: 5-Fu
    Cytotoxicity against human KM12 cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human KM12 cells after 48 hrs by sulforhodamine B assay
    [PMID: 26727215]
    KM12 GI50
    0.21 μM
    Compound: 5-FU
    Anticancer activity against human KM12 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human KM12 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    KM12 GI50
    0.21 μM
    Compound: 5-FU
    Growth inhibition of human KM12 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human KM12 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    KM12 IC50
    12.26 μM
    Compound: 5-FU
    Anticancer activity against human KM12 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Anticancer activity against human KM12 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    [PMID: 34438126]
    KM12 IC50
    14.8 μM
    Compound: 5-Fu
    Cytotoxicity against human KM12 cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human KM12 cells after 48 hrs by sulforhodamine B assay
    [PMID: 26727215]
    KM12 IC50
    7.94 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human KM12 cells assessed as inhibition of tumor growth after 24 hrs
    Cytotoxicity against human KM12 cells assessed as inhibition of tumor growth after 24 hrs
    [PMID: 24657568]
    L02 IC50
    > 10 μM
    Compound: 5-Fu
    Cytotoxicity against human LO2 cells after 48 hrs by MTT assay
    Cytotoxicity against human LO2 cells after 48 hrs by MTT assay
    [PMID: 26714048]
    L02 IC50
    > 200 μM
    Compound: 5-FU
    Cytotoxicity against human LO2 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human LO2 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 31673307]
    L02 IC50
    > 40 μM
    Compound: 5-Fu
    Antiproliferative activity against human L02 cells assessed as reduction in cell growth after 72 hrs by MTT assay
    Antiproliferative activity against human L02 cells assessed as reduction in cell growth after 72 hrs by MTT assay
    [PMID: 31883693]
    L02 IC50
    > 50 μM
    Compound: 5-Fu
    Cytotoxicity against human L02 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity against human L02 cells assessed as cell viability after 48 hrs by MTT assay
    [PMID: 31877536]
    L02 IC50
    > 50 μM
    Compound: 5-Fu
    Cytotoxicity against human L02 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human L02 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 31202992]
    L02 IC50
    10.6 μM
    Compound: Fluorouracil
    Cytotoxicity against human LO2 cells assessed as reduction in cell viability by MTT assay
    Cytotoxicity against human LO2 cells assessed as reduction in cell viability by MTT assay
    [PMID: 31013087]
    L02 IC50
    12.85 μM
    Compound: 5-FU
    Cytotoxicity against human HL-7702 cells assessed as growth inhibition after 72 hrs by CCK8 assay
    Cytotoxicity against human HL-7702 cells assessed as growth inhibition after 72 hrs by CCK8 assay
    [PMID: 27597411]
    L02 IC50
    14.53 μg/mL
    Compound: 5-Fu
    Cytotoxicity against human HL7702 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human HL7702 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    [PMID: 27262600]
    L02 IC50
    19.1 μM
    Compound: 5-FU
    Anti-proliferative activity against human L02 cells after 48 hrs by MTT assay
    Anti-proliferative activity against human L02 cells after 48 hrs by MTT assay
    [PMID: 28947149]
    L02 IC50
    19.12 μM
    Compound: 5-Fu
    Cytotoxicity in human L02 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity in human L02 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 30981113]
    L02 IC50
    25.9 μM
    Compound: 5-FU
    Cytotoxicity against human L02 measured after 72 hrs by MTT assay
    Cytotoxicity against human L02 measured after 72 hrs by MTT assay
    [PMID: 27537924]
    L02 IC50
    25.9 μM
    Compound: 5-FU
    Cytotoxicity against human L02 cells after 72 hrs by MTT assay
    Cytotoxicity against human L02 cells after 72 hrs by MTT assay
    [PMID: 26595184]
    L02 IC50
    29.53 μM
    Compound: 5-Fu
    Cytotoxicity against human LO2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human LO2 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 31509699]
    L02 IC50
    32.546 μM
    Compound: 5-FU
    Antiproliferative activity against human LO2 cells after 72 hrs by CCK-8 assay
    Antiproliferative activity against human LO2 cells after 72 hrs by CCK-8 assay
    [PMID: 28301815]
    L02 IC50
    44.05 μM
    Compound: 5-FU
    Antiproliferative activity against human L02 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay
    Antiproliferative activity against human L02 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay
    [PMID: 37122546]
    L02 IC50
    46 μM
    Compound: 5-FU
    Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay
    Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay
    [PMID: 28756264]
    L02 IC50
    46.57 μM
    Compound: 5-Fu
    Growth inhibition of human L02 cells after 48 hrs by MTT assay
    Growth inhibition of human L02 cells after 48 hrs by MTT assay
    [PMID: 23353737]
    L02 IC50
    46.57 μM
    Compound: 5-Fu
    Cytotoxicity against human L02 cells by after 48 hrs by MTT assay
    Cytotoxicity against human L02 cells by after 48 hrs by MTT assay
    [PMID: 22579780]
    L02 IC50
    56 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human L02 cells after 48 hrs by MTT assay
    Cytotoxicity against human L02 cells after 48 hrs by MTT assay
    [PMID: 21131104]
    L02 IC50
    58.74 μM
    Compound: 5-FU
    Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay
    Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay
    [PMID: 30108826]
    L02 IC50
    58.74 μM
    Compound: 5-FU
    Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay
    Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay
    [PMID: 30092368]
    L02 IC50
    58.74 μM
    Compound: 5-FU
    Cytotoxicity against human HL7702 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity against human HL7702 cells assessed as cell viability after 48 hrs by MTT assay
    [PMID: 25841199]
    L02 IC50
    95.36 μM
    Compound: 5-FU
    Cytotoxicity against human HL-7702 cells assessed as growth inhibition by MTT assay
    Cytotoxicity against human HL-7702 cells assessed as growth inhibition by MTT assay
    [PMID: 24684840]
    L1210 IC50
    > 500 μM
    Compound: 5-FU
    Inhibition of DNA synthesis in mouse L1210 cells assessed as [methyl-3H]thymidine incorporation in to DNA preincubated for 24 hrs by liquid scintillation counting
    Inhibition of DNA synthesis in mouse L1210 cells assessed as [methyl-3H]thymidine incorporation in to DNA preincubated for 24 hrs by liquid scintillation counting
    [PMID: 21330014]
    L1210 IC50
    > 500 μM
    Compound: 5-FU
    Inhibition of DNA synthesis in mouse L1210 cells assessed as [methyl-3H]thymidine incorporation in to DNA by liquid scintillation counting
    Inhibition of DNA synthesis in mouse L1210 cells assessed as [methyl-3H]thymidine incorporation in to DNA by liquid scintillation counting
    [PMID: 21330014]
    L1210 IC50
    ≥ 10 μM
    Compound: 5-FU
    Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15 mins by liquid scintillation counting
    Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15 mins by liquid scintillation counting
    [PMID: 21330014]
    L1210 IC50
    0.02 μM
    Compound: 5-FU
    Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 hrs by liquid scintillation counting
    Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 hrs by liquid scintillation counting
    [PMID: 21330014]
    L1210 IC50
    0.06 μM
    Compound: 5-FU
    Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24 hrs by liquid scintillation counting
    Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24 hrs by liquid scintillation counting
    [PMID: 21330014]
    L1210 IC50
    0.22 μM
    Compound: 5-FU
    Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 hrs by liquid scintillation counting
    Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 hrs by liquid scintillation counting
    [PMID: 21330014]
    L1210 IC50
    0.32 μM
    Compound: 1, 5-FU
    Cytostatic activity against thymidine-kinase deficient mouse L1210 cells after 48 hrs by cell counting
    Cytostatic activity against thymidine-kinase deficient mouse L1210 cells after 48 hrs by cell counting
    [PMID: 21892829]
    L1210 IC50
    0.33 μM
    Compound: 5-Fluorouracil
    Anti-proliferative activity against mouse L1210 cells measured after 48 hrs by coulter counter method
    Anti-proliferative activity against mouse L1210 cells measured after 48 hrs by coulter counter method
    [PMID: 27750154]
    L1210 IC50
    0.33 μM
    Compound: 5-FU
    Cytostatic activity against mouse L1210 cells after 48 hrs by Coulter counting
    Cytostatic activity against mouse L1210 cells after 48 hrs by Coulter counting
    [PMID: 25435471]
    L1210 IC50
    0.33 μM
    Compound: 5-Fluorouracil
    Cytostatic activity against mouse L1210 cells assessed as inhibition of proliferation after 48 hrs by Coulter cell counting method
    Cytostatic activity against mouse L1210 cells assessed as inhibition of proliferation after 48 hrs by Coulter cell counting method
    [PMID: 24906510]
    L1210 IC50
    0.33 μM
    Compound: 5FU
    Cytotoxicity against mouse L1210 cells assessed as reduction in cell number after 48 hrs by cell counting assay
    Cytotoxicity against mouse L1210 cells assessed as reduction in cell number after 48 hrs by cell counting assay
    [PMID: 24631358]
    L1210 IC50
    0.37 μM
    Compound: 5-FU
    Inhibition of DNA synthesis in mouse L1210 cells assessed as [6-3H]2'-deoxyuridine incorporation in to DNA preincubated for 24 hrs by liquid scintillation counting
    Inhibition of DNA synthesis in mouse L1210 cells assessed as [6-3H]2'-deoxyuridine incorporation in to DNA preincubated for 24 hrs by liquid scintillation counting
    [PMID: 21330014]
    L1210 IC50
    0.49 μM
    Compound: 5-Fluorouracil
    Cytostatic activity against mouse L1210 cells after 2 days by coulter counter analysis
    Cytostatic activity against mouse L1210 cells after 2 days by coulter counter analysis
    [PMID: 22405290]
    L1210 IC50
    0.56 μM
    Compound: 5-FU
    Cytostatic activity against mouse L1210 cells after 2 days by coulter counting analysis
    Cytostatic activity against mouse L1210 cells after 2 days by coulter counting analysis
    [PMID: 21330014]
    L1210 IC50
    0.56 μM
    Compound: 5-FU
    Cytotoxicity against mouse L1210 cells after 2 days by coulter counter analysis
    Cytotoxicity against mouse L1210 cells after 2 days by coulter counter analysis
    [PMID: 21232828]
    L1210 IC50
    0.6 μM
    Compound: 5-FU
    Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 hrs by liquid scintillation counting
    Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 hrs by liquid scintillation counting
    [PMID: 21330014]
    L1210 IC50
    0.69 μM
    Compound: 5-FU
    Antiproliferative activity against mouse L1210 cells after 2 days by MTT assay
    Antiproliferative activity against mouse L1210 cells after 2 days by MTT assay
    [PMID: 18424155]
    L1210 IC50
    0.97 μM
    Compound: 5-FU
    Inhibition of DNA synthesis in mouse L1210 cells assessed as [6-3H]2'-deoxyuridine incorporation in to DNA by liquid scintillation counting
    Inhibition of DNA synthesis in mouse L1210 cells assessed as [6-3H]2'-deoxyuridine incorporation in to DNA by liquid scintillation counting
    [PMID: 21330014]
    L1210 IC50
    1.1 pM
    Compound: 5-FU
    Cytotoxicity against mouse L1210 cells after 72 hrs by MTT assay
    Cytotoxicity against mouse L1210 cells after 72 hrs by MTT assay
    [PMID: 21640594]
    L1210 ED50
    1.41 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against mouse L1210 cells after 3 days by trypan blue exclusion technique
    Cytotoxicity against mouse L1210 cells after 3 days by trypan blue exclusion technique
    [PMID: 1800632]
    L1210 IC50
    1010 nM
    Compound: 5-FU
    Growth inhibition in L1210 mouse leukemia cells after 8 h treatment
    Growth inhibition in L1210 mouse leukemia cells after 8 h treatment
    [PMID: 11728193]
    L1210 IC50
    200 nM
    Compound: 5-FU
    Growth inhibition in L1210 mouse leukemia cells after 48 hr treatment
    Growth inhibition in L1210 mouse leukemia cells after 48 hr treatment
    [PMID: 11728193]
    L1210 IC50
    2500 nM
    Compound: 5-FU
    Growth inhibition in L1210 mouse leukemia cells after 2 hr treatment
    Growth inhibition in L1210 mouse leukemia cells after 2 hr treatment
    [PMID: 11728193]
    L1210 IC50
    360 nM
    Compound: 5-FU
    Growth inhibition in L1210 mouse leukemia cells after 24 h treatment
    Growth inhibition in L1210 mouse leukemia cells after 24 h treatment
    [PMID: 11728193]
    L1210 IC50
    4.9 μM
    Compound: 5-FU
    Inhibition of RNA synthesis in mouse L1210 cells assessed as [5-3H]uridine incorporation in to RNA preincubated for 24 hrs by liquid scintillation counting
    Inhibition of RNA synthesis in mouse L1210 cells assessed as [5-3H]uridine incorporation in to RNA preincubated for 24 hrs by liquid scintillation counting
    [PMID: 21330014]
    L1210 IC50
    51 μM
    Compound: 5-FU
    Inhibition of RNA synthesis in mouse L1210 cells assessed as [5-3H]uridine incorporation in to RNA by liquid scintillation counting
    Inhibition of RNA synthesis in mouse L1210 cells assessed as [5-3H]uridine incorporation in to RNA by liquid scintillation counting
    [PMID: 21330014]
    L1210 IC50
    7 μM
    Compound: 5-FU
    Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 mins by liquid scintillation counting
    Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 mins by liquid scintillation counting
    [PMID: 21330014]
    L1210/C IC50
    0.2 μg/mL
    Compound: 5-FU
    The compound was evaluated for antitumoral activity against mouse leukemia cell line L1210/c after 72 hr of incubation
    The compound was evaluated for antitumoral activity against mouse leukemia cell line L1210/c after 72 hr of incubation
    10.1016/S0960-894X(01)80742-3
    L929 IC50
    > 100 μM
    Compound: 5-Fu
    Cytotoxicity against mouse L929 cells assessed as inhibition of cell proliferation by MTT assay
    Cytotoxicity against mouse L929 cells assessed as inhibition of cell proliferation by MTT assay
    [PMID: 36336316]
    L929 IC50
    1.38 μM
    Compound: 5-Fu
    Cytotoxicity against mouse L929 cells after 72 hrs by MTT assay
    Cytotoxicity against mouse L929 cells after 72 hrs by MTT assay
    [PMID: 22687745]
    L929 IC50
    2.98 μM
    Compound: 5-Fu
    Antiproliferative activity against mouse L929 cells after 48 hrs by CCK8 assay
    Antiproliferative activity against mouse L929 cells after 48 hrs by CCK8 assay
    [PMID: 26786698]
    Leukemia cell GI50
    1.51 μM
    Compound: 5-FU
    Cytotoxicity against human leukemia cells after 48 hrs by SRB assay
    Cytotoxicity against human leukemia cells after 48 hrs by SRB assay
    [PMID: 23994328]
    Leukemia cell GI50
    15.09 μM
    Compound: 5-FU
    Growth inhibition of human leukemia cells after 48 hrs
    Growth inhibition of human leukemia cells after 48 hrs
    [PMID: 18950904]
    Leukemia cell GI50
    15.1 μM
    Compound: 5-FU
    Cytotoxicity against human leukemia cells after 48 hrs by coulter counter analysis
    Cytotoxicity against human leukemia cells after 48 hrs by coulter counter analysis
    [PMID: 23683592]
    Leukemia cell GI50
    15.1 μM
    Compound: 5-FU
    Growth inhibition of human leukemia cells after 48 hrs by coulter counter method
    Growth inhibition of human leukemia cells after 48 hrs by coulter counter method
    [PMID: 22119151]
    Leukemia cell GI50
    15.1 μM
    Compound: 5-FU
    Cytotoxicity against human leukemia cells after 48 hrs by coulter counting
    Cytotoxicity against human leukemia cells after 48 hrs by coulter counting
    [PMID: 22056277]
    Leukemia cell GI50
    15.1 μM
    Compound: 5-FU
    Growth inhibition of human leukemia cells after 48 hrs by SRB assay
    Growth inhibition of human leukemia cells after 48 hrs by SRB assay
    [PMID: 27554444]
    Leukemia cell GI50
    15.1 μM
    Compound: 5-fu
    Antitumor activity against human leukemia cells after 48 hrs by SRB assay
    Antitumor activity against human leukemia cells after 48 hrs by SRB assay
    [PMID: 20350811]
    Leukemia cell GI50
    15.1 μM
    Compound: 5-FU
    Cytotoxicity against human leukemia cells at 10 uM after 48 hrs
    Cytotoxicity against human leukemia cells at 10 uM after 48 hrs
    [PMID: 24469112]
    Leukemia cell GI50
    15.1 μM
    Compound: 5-FU
    Cytotoxicity against human leukemia cells after 48 hrs by sulphorhodamine B assay
    Cytotoxicity against human leukemia cells after 48 hrs by sulphorhodamine B assay
    [PMID: 23474899]
    Leukemia cell GI50
    15.1 μM
    Compound: 5-fu
    Antiproliferative activity against human leukemia cells after 48 hrs by cell counting analysis
    Antiproliferative activity against human leukemia cells after 48 hrs by cell counting analysis
    [PMID: 22995621]
    Lewis lung carcinoma cell line IC50
    2.59 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against mouse LLC cells after 72 hrs by MTT assay
    Cytotoxicity against mouse LLC cells after 72 hrs by MTT assay
    [PMID: 18440233]
    Lewis lung carcinoma cell line IC50
    2.9 μg/mL
    Compound: 5-Fu
    Anticancer activity against mouse LL/2 cells assessed as growth inhibition after 48 hrs by MTT assay
    Anticancer activity against mouse LL/2 cells assessed as growth inhibition after 48 hrs by MTT assay
    [PMID: 25017036]
    LFCl2A IC50
    28.5 μM
    Compound: 5-fluoro uracil
    In vitro cytotoxic activity against LFCl2A cell line derived from an hepatocarcinoma induced in the commentary rat by dimethylaminoazobenzene
    In vitro cytotoxic activity against LFCl2A cell line derived from an hepatocarcinoma induced in the commentary rat by dimethylaminoazobenzene
    10.1016/S0960-894X(00)80263-2
    LNCaP IC50
    0.03 μM
    Compound: 5-FU
    Cytotoxicity against human LNCAP cells assessed as growth inhibition after 24 hrs by sulforhodamine B assay
    Cytotoxicity against human LNCAP cells assessed as growth inhibition after 24 hrs by sulforhodamine B assay
    [PMID: 27156770]
    LNCaP IC50
    4.9 μM
    Compound: 5-FU
    Antiproliferative activity against prostate cancer LNCaP Cell line using sulforhodamine B(SRB) assay
    Antiproliferative activity against prostate cancer LNCaP Cell line using sulforhodamine B(SRB) assay
    [PMID: 15801848]
    LNCaP IC50
    4.9 μM
    Compound: 5-FU
    Antiproliferative activity against human prostate cancer LNCaP cell line by sulforhodamine B assay
    Antiproliferative activity against human prostate cancer LNCaP cell line by sulforhodamine B assay
    [PMID: 16005217]
    LNCaP IC50
    4.9 μM
    Compound: 5-FU
    Antiproliferative activity was evaluated against human prostate LNCaP cancer cell lines using the sulforhodamine B (STB) assay
    Antiproliferative activity was evaluated against human prostate LNCaP cancer cell lines using the sulforhodamine B (STB) assay
    [PMID: 15454213]
    LNCaP IC50
    47.18 μM
    Compound: F
    Cytotoxicity against human LNCAP cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human LNCAP cells assessed as decrease in cell viability after 48 hrs by MTT assay
    [PMID: 27210438]
    LNCaP IC50
    5.21 μM
    Compound: 5-FU
    Antiproliferative activity against human LNCAP cells after 48 hrs by MTT assay
    Antiproliferative activity against human LNCAP cells after 48 hrs by MTT assay
    [PMID: 28666860]
    LNCaP C4-2B IC50
    38.2 μM
    Compound: 5-FU
    Antiproliferative activity against human C4-2B cells after 48 hrs by MTT assay
    Antiproliferative activity against human C4-2B cells after 48 hrs by MTT assay
    [PMID: 30108895]
    LNCaP C4-2B IC50
    5.64 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human C4-2B cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
    Antiproliferative activity against human C4-2B cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
    [PMID: 27295506]
    LoVo IC50
    11.5 μM
    Compound: 5-FU
    Growth inhibition of human LoVo cells after 48 hrs by CCK-8 assay
    Growth inhibition of human LoVo cells after 48 hrs by CCK-8 assay
    [PMID: 30106289]
    LoVo IC50
    12.6 μM
    Compound: 5-FU
    Anticancer activity against human LoVo cells assessed as inhibition of cell proliferation by MTT assay
    Anticancer activity against human LoVo cells assessed as inhibition of cell proliferation by MTT assay
    [PMID: 36439975]
    LoVo IC50
    12.7 μM
    Compound: 5-Fu
    Antiproliferative activity against human LoVo cells assessed as cell-growth inhibition after 48 hrs by MTT assay
    Antiproliferative activity against human LoVo cells assessed as cell-growth inhibition after 48 hrs by MTT assay
    [PMID: 25453794]
    LoVo IC50
    2.7 μM
    Compound: 5-FU
    Antiproliferative activity against human LoVo cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human LoVo cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 32127259]
    LoVo IC50
    3.3 μM
    Compound: 5-Fu
    Antiproliferative activity against human LoVo cells after 48 hrs by MTT assay
    Antiproliferative activity against human LoVo cells after 48 hrs by MTT assay
    [PMID: 22840493]
    LoVo IC50
    4.69 μM
    Compound: FUra
    Antiproliferative activity against human LoVo cells assessed as growth inhibition after 72 hrs by SRB method
    Antiproliferative activity against human LoVo cells assessed as growth inhibition after 72 hrs by SRB method
    [PMID: 25644674]
    LoVo IC50
    8.35 μM
    Compound: 5-FU
    Antitumor activity against human LoVo cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    Antitumor activity against human LoVo cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    [PMID: 35777102]
    LOX IMVI GI50
    0.24 μM
    Compound: 5-FU
    Growth inhibition of human LOXIMVI cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human LOXIMVI cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    LS180 IC50
    38.92 μM
    Compound: FUra
    Antiproliferative activity against human LS180 cells assessed as growth inhibition after 72 hrs by SRB method
    Antiproliferative activity against human LS180 cells assessed as growth inhibition after 72 hrs by SRB method
    [PMID: 25644674]
    M14 GI50
    0.7 μg/mL
    Compound: 5FU
    Cytotoxicity against human M14 cells assessed as growth inhibition after 48 hrs by SRB assay method
    Cytotoxicity against human M14 cells assessed as growth inhibition after 48 hrs by SRB assay method
    [PMID: 26383125]
    M14 GI50
    0.98 μM
    Compound: 5-FU
    Anticancer activity against human M14 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human M14 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    M14 GI50
    0.98 μM
    Compound: 5-FU
    Growth inhibition of human M14 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human M14 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    M14 GI50
    22.4 μM
    Compound: 5FU
    Cytotoxicity against human M14 cells after 48 hrs
    Cytotoxicity against human M14 cells after 48 hrs
    [PMID: 18798609]
    Mahlavu IC50
    10 μM
    Compound: 5-FU
    Antiproliferative activity against human Mahlavu cells after 72 hrs by SRB assay
    Antiproliferative activity against human Mahlavu cells after 72 hrs by SRB assay
    [PMID: 29326016]
    Mahlavu IC50
    10 μM
    Compound: 5-Fu
    Cytotoxicity against human Mahlavu cells after 72 hrs by SRB assay
    Cytotoxicity against human Mahlavu cells after 72 hrs by SRB assay
    [PMID: 22409771]
    Malme-3M GI50
    0.05 μM
    Compound: 5-FU
    Anticancer activity against human Malme-3M cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human Malme-3M cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    Malme-3M GI50
    0.05 μM
    Compound: 5-FU
    Growth inhibition of human MALME-3M cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human MALME-3M cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    MCF-10A IC50
    > 20 μM
    Compound: 5-FU
    Cytotoxicity against human MCF-10A cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    Cytotoxicity against human MCF-10A cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    [PMID: 36331508]
    MCF-10A IC50
    > 20 μM
    Compound: 5-FU
    Cytotoxicity against human MCF10A cells assessed as reduction in cell viability after 72 hrs by MTS assay
    Cytotoxicity against human MCF10A cells assessed as reduction in cell viability after 72 hrs by MTS assay
    [PMID: 30472605]
    MCF-10A IC50
    0.73 μM
    Compound: 5-FU
    Cytotoxicity against human MCF10A cells after 6 days by SRB colorimetric assay
    Cytotoxicity against human MCF10A cells after 6 days by SRB colorimetric assay
    [PMID: 21684047]
    MCF-10A IC50
    17.2 μM
    Compound: 5-FU
    Antiproliferation activity against human MCF-10A cells assessed as reduction in cell viability under hypoxic conditions by MTT assay
    Antiproliferation activity against human MCF-10A cells assessed as reduction in cell viability under hypoxic conditions by MTT assay
    [PMID: 33965860]
    MCF-10A IC50
    39.7 μM
    Compound: 5-FU
    Cytotoxicity against human MCF-10A cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human MCF-10A cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 33166925]
    MCF-10A IC50
    8.06 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF10A cells after 3 days by SRB assay
    Cytotoxicity against human MCF10A cells after 3 days by SRB assay
    [PMID: 24704691]
    MCF7 GI50
    > 10 μM
    Compound: 5-Fu
    Growth inhibition of human MCF7 cells after 72 hrs by Alamar Blue assay
    Growth inhibition of human MCF7 cells after 72 hrs by Alamar Blue assay
    [PMID: 19406645]
    MCF7 IC50
    > 100 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 31803401]
    MCF7 IC50
    > 100 μM
    Compound: 5-FU
    Cytotoxicity against drug-resistant TCCD-induced human MCF7 cells overexpressing CYP1B1 assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against drug-resistant TCCD-induced human MCF7 cells overexpressing CYP1B1 assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 31803401]
    MCF7 IC50
    > 100 μM
    Compound: 5-FU
    Antitumor activity against human MCF7 cells assessed as growth inhibition measured after 48 hrs by MTT assay
    Antitumor activity against human MCF7 cells assessed as growth inhibition measured after 48 hrs by MTT assay
    [PMID: 23313635]
    MCF7 IC50
    > 100 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 22537362]
    MCF7 IC50
    > 100 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay
    Cytotoxicity against human MCF7 cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay
    [PMID: 31416740]
    MCF7 IC50
    > 20 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    [PMID: 36331508]
    MCF7 IC50
    > 200 μM
    Compound: 5-FLU
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
    [PMID: 34606997]
    MCF7 IC50
    0.0052 mM
    Compound: 5-FU
    Cytotoxicity against Homo sapiens (human) MCF7 cells assessed as growth inhibition after 72 hr by MTT assay
    Cytotoxicity against Homo sapiens (human) MCF7 cells assessed as growth inhibition after 72 hr by MTT assay
    10.1007/s00044-012-0181-0
    MCF7 IC50
    0.02 mM
    Compound: 5-FU
    Cytotoxicity against Homo sapiens (human) MCF7 cells assessed as inhibition of cell survival after 96 hr
    Cytotoxicity against Homo sapiens (human) MCF7 cells assessed as inhibition of cell survival after 96 hr
    10.1007/s00044-012-0201-0
    MCF7 IC50
    0.0415 mM
    Compound: 5-Fluorouracil
    Cytotoxicity in human MCF7 cells assessed as reduction in cell viability by MTT assay
    Cytotoxicity in human MCF7 cells assessed as reduction in cell viability by MTT assay
    [PMID: 28334654]
    MCF7 GI50
    0.07 μM
    Compound: 5-FU
    Anticancer activity against human MCF7 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human MCF7 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    MCF7 GI50
    0.07 μM
    Compound: 5-FU
    Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    MCF7 IC50
    0.09 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 26617970]
    MCF7 IC50
    0.12 x 10-2 μg/mL
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells by MTT assay
    Cytotoxicity against human MCF7 cells by MTT assay
    [PMID: 16038565]
    MCF7 ED50
    0.2 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human MCF7 cells by MTT assay
    Cytotoxicity against human MCF7 cells by MTT assay
    [PMID: 16309328]
    MCF7 GI50
    0.3 μg/mL
    Compound: 5FU
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by SRB assay method
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by SRB assay method
    [PMID: 26383125]
    MCF7 IC50
    0.3 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 19743863]
    MCF7 IC50
    0.3 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 72 hrs
    Antiproliferative activity against human MCF7 cells after 72 hrs
    [PMID: 17548198]
    MCF7 IC50
    0.59 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF-7 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
    Antiproliferative activity against human MCF-7 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay
    [PMID: 32485532]
    MCF7 IC50
    0.67 μg/mL
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 22154835]
    MCF7 IC50
    0.67 μg/mL
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay
    Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay
    [PMID: 19932530]
    MCF7 IC50
    0.69 mg/mL
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells after 3 days MTT assay
    Cytotoxicity against human MCF7 cells after 3 days MTT assay
    [PMID: 22796042]
    MCF7 IC50
    0.9 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay
    Antiproliferative activity against human MCF7 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay
    [PMID: 26731300]
    MCF7 IC50
    1.2 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay
    [PMID: 24060486]
    MCF7 IC50
    1.25 μM
    Compound: 5-Florouracil
    Anticancer activity against Homo sapiens (human) MCF7 cells assessed as inhibition of cell proliferation after 24 hr by MTT assay
    Anticancer activity against Homo sapiens (human) MCF7 cells assessed as inhibition of cell proliferation after 24 hr by MTT assay
    10.1007/s00044-012-0260-2
    MCF7 IC50
    1.4 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay
    [PMID: 24835633]
    MCF7 IC50
    1.4 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
    Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
    [PMID: 30108969]
    MCF7 IC50
    1.4 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by SRB assay
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by SRB assay
    [PMID: 28219046]
    MCF7 IC50
    1.5 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells by MTT assay
    Cytotoxicity against human MCF7 cells by MTT assay
    [PMID: 18606546]
    MCF7 IC50
    1.5 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells by MTT microassay
    Cytotoxicity against human MCF7 cells by MTT microassay
    [PMID: 17320246]
    MCF7 GI50
    1.67 μM
    Compound: 5-FU
    Growth inhibition of human MCF7 cells after 48 hrs by SRB assay
    Growth inhibition of human MCF7 cells after 48 hrs by SRB assay
    [PMID: 28400235]
    MCF7 IC50
    1.7 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as cell growth inhibition by MTT assay
    Cytotoxicity against human MCF7 cells assessed as cell growth inhibition by MTT assay
    [PMID: 34000484]
    MCF7 IC50
    1.75 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 28165738]
    MCF7 IC50
    1.8 μM
    Compound: 5-Fluoro uracilc
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 24 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 24 hrs by MTT assay
    [PMID: 24641975]
    MCF7 IC50
    1.8 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human MCF7 cells by MTT assay
    Antiproliferative activity against human MCF7 cells by MTT assay
    [PMID: 29798826]
    MCF7 IC50
    1.9 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    [PMID: 27528432]
    MCF7 IC50
    10.14 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 23685571]
    MCF7 IC50
    10.2 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 29133037]
    MCF7 IC50
    10.4 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    [PMID: 32987314]
    MCF7 IC50
    10.6 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay
    [PMID: 29133037]
    MCF7 IC50
    10.8 μg/mL
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    [PMID: 27262600]
    MCF7 IC50
    10.92 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay
    [PMID: 35290844]
    MCF7 IC50
    11.1 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as cell survivability after 24 hrs by crystal violet staining based microscopic analysis
    Cytotoxicity against human MCF7 cells assessed as cell survivability after 24 hrs by crystal violet staining based microscopic analysis
    [PMID: 27234893]
    MCF7 IC50
    11.5 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells assessed as induction of cell death incubated for 2 days by MTT assay
    Cytotoxicity against human MCF7 cells assessed as induction of cell death incubated for 2 days by MTT assay
    [PMID: 26259802]
    MCF7 IC50
    11.5 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells after 2 days by MTT assay
    Cytotoxicity against human MCF7 cells after 2 days by MTT assay
    [PMID: 24767839]
    MCF7 IC50
    11.5 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
    [PMID: 27189676]
    MCF7 IC50
    11.5 μM
    Compound: 5-Fu
    Growth inhibition against human MCF7 cells after 48 hrs by MTT assay
    Growth inhibition against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 23999046]
    MCF7 IC50
    11.5 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 23558238]
    MCF7 IC50
    12.1 μg/mL
    Compound: 5-Fu
    Anticancer activity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
    Anticancer activity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay
    [PMID: 25017036]
    MCF7 IC50
    12.24 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 25707012]
    MCF7 IC50
    12.3 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay
    [PMID: 33799070]
    MCF7 IC50
    12.5 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 22727445]
    MCF7 IC50
    12.5 μM
    Compound: 5-FU
    Antiproliferation activity against human MCF7 cells assessed as reduction in cell viability under hypoxic conditions by MTT assay
    Antiproliferation activity against human MCF7 cells assessed as reduction in cell viability under hypoxic conditions by MTT assay
    [PMID: 33965860]
    MCF7 IC50
    12.6 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    [PMID: 32987314]
    MCF7 IC50
    13.16 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    [PMID: 33248852]
    MCF7 IC50
    13.19 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by CCK8 assay
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by CCK8 assay
    [PMID: 27597411]
    MCF7 IC50
    13.5 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 27133593]
    MCF7 IC50
    13.5 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    10.1039/C5MD00240K
    MCF7 IC50
    136.5 μM
    Compound: 5-FU
    Cytotoxicity in human MCF-7 cells assessed as growth inhibition incubated for 24 hrs by MTT assay
    Cytotoxicity in human MCF-7 cells assessed as growth inhibition incubated for 24 hrs by MTT assay
    [PMID: 31128448]
    MCF7 IC50
    14 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 22130132]
    MCF7 IC50
    14.1 μg/mL
    Compound: 5-Fluorouracil
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 21109433]
    MCF7 IC50
    14.2 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 22749192]
    MCF7 IC50
    14.26 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation by CCK8 assay
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation by CCK8 assay
    [PMID: 25442303]
    MCF7 GI50
    14.5 nM
    Compound: 5FU
    Growth inhibition of human MCF7 cells after 48 hrs by SRB assay
    Growth inhibition of human MCF7 cells after 48 hrs by SRB assay
    [PMID: 23094992]
    MCF7 IC50
    14.7 μM
    Compound: 5-Fu
    Cytotoxicity in human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Cytotoxicity in human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    [PMID: 28987604]
    MCF7 IC50
    15 μM
    Compound: 5 Fluorouracil
    Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    [PMID: 27496212]
    MCF7 IC50
    15 μM
    Compound: 5-FU
    Antitumor activity against human MCF7 cells after 24 hrs by MTT assay
    Antitumor activity against human MCF7 cells after 24 hrs by MTT assay
    [PMID: 20211564]
    MCF7 IC50
    15 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 19919065]
    MCF7 IC50
    15 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 19795843]
    MCF7 IC50
    15 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 19618920]
    MCF7 GI50
    15 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 19572613]
    MCF7 IC50
    15 μM
    Compound: 5-Fluorouracil
    Cytostatic activity against human MCF7 cells after 72 hrs by MTT assay
    Cytostatic activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 22405290]
    MCF7 IC50
    15 μM
    Compound: 5-FU
    Growth inhibition of human MCF7 cells after 72 hrs by MTT assay
    Growth inhibition of human MCF7 cells after 72 hrs by MTT assay
    [PMID: 18640746]
    MCF7 IC50
    15 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 48 hrs by resazurin reduction test
    Antiproliferative activity against human MCF7 cells after 48 hrs by resazurin reduction test
    [PMID: 21530016]
    MCF7 IC50
    15.14 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    [PMID: 35259487]
    MCF7 IC50
    15.2 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 3 days by MTT assay
    Cytotoxicity against human MCF7 cells after 3 days by MTT assay
    [PMID: 21144621]
    MCF7 IC50
    15.2 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 24 hrs by trypan blue exclusion assay
    Antiproliferative activity against human MCF7 cells after 24 hrs by trypan blue exclusion assay
    [PMID: 20403701]
    MCF7 IC50
    15.78 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 29486954]
    MCF7 IC50
    16.2 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 22840493]
    MCF7 IC50
    16.27 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells measured after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells measured after 48 hrs by MTT assay
    [PMID: 32135407]
    MCF7 IC50
    16.28 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 30981113]
    MCF7 IC50
    16.3 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells assessed as cell-growth inhibition after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as cell-growth inhibition after 48 hrs by MTT assay
    [PMID: 25453794]
    MCF7 IC50
    16.32 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth by SRB assay
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth by SRB assay
    [PMID: 35594653]
    MCF7 IC50
    16.7 μM
    Compound: 5-FU
    Cytotoxicity in human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity in human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 29657100]
    MCF7 IC50
    16.7 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 23490159]
    MCF7 IC50
    166 μM
    Compound: 5-FLU
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    [PMID: 34606997]
    MCF7 IC50
    17.11 μM
    Compound: 5-FU
    Anticancer activity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Anticancer activity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    [PMID: 31577977]
    MCF7 IC50
    17.2 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 23279864]
    MCF7 IC50
    178 μg/mL
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    [PMID: 29207336]
    MCF7 IC50
    18.13 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability by MTT assay
    [PMID: 34157389]
    MCF7 IC50
    18.58 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    [PMID: 33740546]
    MCF7 IC50
    18.75 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 29475156]
    MCF7 IC50
    19.2 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 28073676]
    MCF7 IC50
    19.39 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 26363869]
    MCF7 IC50
    2 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 26854375]
    MCF7 IC50
    2.13 μM
    Compound: 5-Fluorouracil
    Cytotoxicity activity against human MCF7 cells incubated for 48 hrs by SRB assay
    Cytotoxicity activity against human MCF7 cells incubated for 48 hrs by SRB assay
    [PMID: 34119830]
    MCF7 IC50
    2.19 μg/mL
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 29100732]
    MCF7 IC50
    2.2 x 10-1 μg/mL
    Compound: fluorouracil
    Cytotoxicity against human MCF7 cells by MTT assay
    Cytotoxicity against human MCF7 cells by MTT assay
    [PMID: 22011319]
    MCF7 IC50
    2.2 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells measured after 24 hrs by MTT assay
    Cytotoxicity against human MCF7 cells measured after 24 hrs by MTT assay
    [PMID: 34875389]
    MCF7 IC50
    2.3 μg/mL
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay
    [PMID: 22204901]
    MCF7 IC50
    2.3 μg/mL
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 96 hrs
    Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 96 hrs
    [PMID: 29673982]
    MCF7 IC50
    2.3 μg/mL
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells assessed as loss of cell monolayers after 96 hrs
    Cytotoxicity against human MCF7 cells assessed as loss of cell monolayers after 96 hrs
    [PMID: 21130542]
    MCF7 IC50
    2.35 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 29223098]
    MCF7 IC50
    2.36 μM
    Compound: 5-Fluorouracil
    Anticancer activity against human MCF7 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay
    Anticancer activity against human MCF7 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay
    [PMID: 26231080]
    MCF7 IC50
    2.46 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 24 hrs by sulforhodamine B assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 24 hrs by sulforhodamine B assay
    [PMID: 34847409]
    MCF7 IC50
    2.5 μg/mL
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay
    [PMID: 23022735]
    MCF7 GI50
    2.8 μM
    Compound: 5FU
    Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay
    [PMID: 21489802]
    MCF7 IC50
    2.86 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells after 3 days by SRB assay
    Cytotoxicity against human MCF7 cells after 3 days by SRB assay
    [PMID: 24704691]
    MCF7 IC50
    2.9 μM
    Compound: 5-Fu
    Cytotoxicity against Homo sapiens (human) MCF7 cells by SRB assay
    Cytotoxicity against Homo sapiens (human) MCF7 cells by SRB assay
    10.1007/s00044-010-9500-5
    MCF7 IC50
    20.09 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    [PMID: 33894490]
    MCF7 IC50
    21.11 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
    [PMID: 35635947]
    MCF7 IC50
    21.47 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    10.1039/C6MD00061D
    MCF7 IC50
    22.439 μM
    Compound: 5-FU
    Anticancer activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Anticancer activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    [PMID: 34000485]
    MCF7 IC50
    22.6 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 30527868]
    MCF7 IC50
    22.8 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 34883453]
    MCF7 IC50
    222.6 μM
    Compound: 5-Fuorouracil
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 27017265]
    MCF7 IC50
    24.58 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells by MTT assay
    Cytotoxicity against human MCF7 cells by MTT assay
    [PMID: 22801644]
    MCF7 IC50
    26.14 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 28110871]
    MCF7 IC50
    26.14 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 30142612]
    MCF7 IC50
    26.14 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells assessed as cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as cell viability after 72 hrs by MTT assay
    [PMID: 26922223]
    MCF7 IC50
    26.34 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 30709651]
    MCF7 IC50
    26.57 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 30677614]
    MCF7 IC50
    26.65 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 31877536]
    MCF7 IC50
    26.65 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth after 72 hrs by MTT assay
    [PMID: 31883693]
    MCF7 IC50
    26.67 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells expressing p53 gene after 72 hrs by proliferative assay
    Antiproliferative activity against human MCF7 cells expressing p53 gene after 72 hrs by proliferative assay
    [PMID: 18469809]
    MCF7 IC50
    26.9 μM
    Compound: 5-Fu
    Anticancer activity against human MCF7 cells after 48 hrs by MTT assay
    Anticancer activity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 25462264]
    MCF7 IC50
    26.91 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 29635169]
    MCF7 IC50
    27.89 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 30243153]
    MCF7 IC50
    28.73 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 28458133]
    MCF7 IC50
    28.97 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 29174813]
    MCF7 IC50
    29.4 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 30108895]
    MCF7 IC50
    29.41 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    [PMID: 30568759]
    MCF7 IC50
    29.5 μM
    Compound: 5-FU
    Anticancer activity against human MCF7 cells incubated for 72 hrs by MTT assay
    Anticancer activity against human MCF7 cells incubated for 72 hrs by MTT assay
    [PMID: 35367708]
    MCF7 IC50
    3 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 27343853]
    MCF7 IC50
    3 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay
    [PMID: 29326016]
    MCF7 IC50
    3.15 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth after 72 hrs by MTT assay
    [PMID: 32311607]
    MCF7 IC50
    3.18 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 28666860]
    MCF7 IC50
    3.2 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
    [PMID: 31471102]
    MCF7 IC50
    3.5 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 24332497]
    MCF7 IC50
    3.5 μM
    Compound: 5FU
    Cytotoxicity against human MCF7 cells incubated for 72 hrs by SRB assay
    Cytotoxicity against human MCF7 cells incubated for 72 hrs by SRB assay
    [PMID: 22867707]
    MCF7 IC50
    3.5 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
    Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
    [PMID: 22409771]
    MCF7 IC50
    3.52 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 24835817]
    MCF7 GI50
    3.6 μM
    Compound: 5-FU
    Growth inhibition of human MCF7 cells measured after 72 hrs by MTT assay
    Growth inhibition of human MCF7 cells measured after 72 hrs by MTT assay
    [PMID: 27504537]
    MCF7 IC50
    3.6 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 23792763]
    MCF7 IC50
    30 μg/mL
    Compound: 5-Fluorouracil
    Antiproliferative activity against human MCF7 cells by MTT assay
    Antiproliferative activity against human MCF7 cells by MTT assay
    [PMID: 31546197]
    MCF7 IC50
    30 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells by MTT assay
    Cytotoxicity against human MCF7 cells by MTT assay
    [PMID: 28371676]
    MCF7 IC50
    30.41 μM
    Compound: Fluorouracil
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 27128180]
    MCF7 IC50
    31.04 μM
    Compound: 5-Fu
    Anticancer activity against human MCF7 cells overexpressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay
    Anticancer activity against human MCF7 cells overexpressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 31509699]
    MCF7 IC50
    32.18 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTS assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTS assay
    [PMID: 30472605]
    MCF7 IC50
    32.18 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay
    [PMID: 27575478]
    MCF7 IC50
    32.18 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay
    [PMID: 26703795]
    MCF7 IC50
    32.18 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay
    [PMID: 27400887]
    MCF7 IC50
    32.18 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 23665106]
    MCF7 IC50
    32.27 μM
    Compound: F
    Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    [PMID: 27210438]
    MCF7 IC50
    32.626 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 29223717]
    MCF7 IC50
    34 μg/mL
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 36 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 36 hrs by MTT assay
    [PMID: 20961091]
    MCF7 IC50
    34.48 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by WST-1 assay
    Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by WST-1 assay
    [PMID: 25466196]
    MCF7 IC50
    35 μM
    Compound: 5-fu
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 22304344]
    MCF7 IC50
    38.5 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 28756264]
    MCF7 IC50
    39.88 μM
    Compound: Fluorouracil
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 25016234]
    MCF7 IC50
    4.3 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human MCF7 cells after 24 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 24 hrs by MTT assay
    [PMID: 19560842]
    MCF7 IC50
    4.3 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    [PMID: 28623814]
    MCF7 IC50
    4.32 μM
    Compound: 5-FU
    Antiproliferative activity in human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity in human MCF7 cells after 72 hrs by MTT assay
    10.1039/C6MD00252H
    MCF7 IC50
    4.32 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells expressing wild type p53 and ras mutant after 3 days by SRB assay
    Cytotoxicity against human MCF7 cells expressing wild type p53 and ras mutant after 3 days by SRB assay
    [PMID: 21126804]
    MCF7 IC50
    4.32 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 3 days by SRB assay
    Antiproliferative activity against human MCF7 cells after 3 days by SRB assay
    [PMID: 18069093]
    MCF7 IC50
    4.32 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 6 days by SRB colorimetric assay
    Cytotoxicity against human MCF7 cells after 6 days by SRB colorimetric assay
    [PMID: 21684047]
    MCF7 IC50
    4.42 μM
    Compound: 5-FU
    Antitumor activity against human MCF7 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay
    Antitumor activity against human MCF7 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay
    [PMID: 36324491]
    MCF7 IC50
    4.5 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 3 days by MTT assay
    Antiproliferative activity against human MCF7 cells after 3 days by MTT assay
    [PMID: 18424155]
    MCF7 GI50
    4.5 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as growth inhibition measured after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as growth inhibition measured after 48 hrs by MTT assay
    [PMID: 27688184]
    MCF7 IC50
    4.55 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay
    [PMID: 32619887]
    MCF7 IC50
    4.6 μM
    Compound: 5-Fu
    Anticancer activity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    Anticancer activity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    [PMID: 25086915]
    MCF7 IC50
    4.7 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 72 hrs by crystal violet staining
    Cytotoxicity against human MCF7 cells after 72 hrs by crystal violet staining
    [PMID: 22959205]
    MCF7 IC50
    4.7 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human MCF7 after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 after 72 hrs by MTT assay
    [PMID: 19233650]
    MCF7 IC50
    4.7 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 144 hrs by crystal violet staining method
    Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 144 hrs by crystal violet staining method
    [PMID: 22450132]
    MCF7 IC50
    4.7 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 72 hrs by crystal violet staining method
    Antiproliferative activity against human MCF7 cells after 72 hrs by crystal violet staining method
    [PMID: 22765897]
    MCF7 IC50
    4.76 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    [PMID: 32682202]
    MCF7 IC50
    4.8 μg/mL
    Compound: 5-flourouracil
    Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    [PMID: 27597407]
    MCF7 IC50
    4.8 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human MCF7 cells after 72 hrs
    Cytotoxicity against human MCF7 cells after 72 hrs
    [PMID: 17336074]
    MCF7 IC50
    41.51 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay
    [PMID: 31401008]
    MCF7 IC50
    42.01 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 21524829]
    MCF7 IC50
    42.78 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 26883148]
    MCF7 IC50
    42.78 μM
    Compound: 5FU
    Cytotoxicity against human MCF7 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay
    Cytotoxicity against human MCF7 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay
    [PMID: 28038327]
    MCF7 IC50
    5 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 23800391]
    MCF7 IC50
    5.012 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 26301558]
    MCF7 IC50
    5.05 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    [PMID: 36242987]
    MCF7 IC50
    5.2 x 10-1 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 72 hrs by CCK8 assay
    Cytotoxicity against human MCF7 cells after 72 hrs by CCK8 assay
    [PMID: 26725029]
    MCF7 IC50
    5.2 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 28759877]
    MCF7 IC50
    5.32 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    [PMID: 33385852]
    MCF7 IC50
    5.4 μM
    Compound: 5-Fu
    Anticancer activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Anticancer activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 35694689]
    MCF7 IC50
    5.4 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 31276896]
    MCF7 IC50
    5.44 μM
    Compound: 5-Fu
    Antiproliferation activity against human MCF-7 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    Antiproliferation activity against human MCF-7 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    [PMID: 34186178]
    MCF7 IC50
    5.6 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by WST8 assay
    Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by WST8 assay
    [PMID: 28558970]
    MCF7 IC50
    5.7 μM
    Compound: 5-Fluorouracil
    Antitumor activity against human MCF7 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay
    Antitumor activity against human MCF7 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay
    [PMID: 28926764]
    MCF7 IC50
    5.8 μM
    Compound: 5-FU
    Cytotoxicity against ERalpha-dependent human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against ERalpha-dependent human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 33166925]
    MCF7 IC50
    52.07 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 31673307]
    MCF7 IC50
    57 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 31057737]
    MCF7 IC50
    57.09 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 30108924]
    MCF7 IC50
    6.11 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 29254641]
    MCF7 GI50
    6.5 μM
    Compound: 5FU
    Cytotoxicity against human MCF7 cells after 48 hrs
    Cytotoxicity against human MCF7 cells after 48 hrs
    [PMID: 18798609]
    MCF7 IC50
    6.53 μM
    Compound: FUra
    Cytotoxicity against human MCF7cells after 72 hrs by SRB assay
    Cytotoxicity against human MCF7cells after 72 hrs by SRB assay
    [PMID: 27073055]
    MCF7 IC50
    6.53 μM
    Compound: FUra
    Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
    Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay
    [PMID: 23867603]
    MCF7 IC50
    6.53 μM
    Compound: FUra
    Cytotoxicity against human MCF7 cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay
    [PMID: 27501415]
    MCF7 IC50
    63 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by MTT assay
    [PMID: 29908443]
    MCF7 IC50
    64 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells expressing p53 after 72 hrs by celltiter-glo assay
    Antiproliferative activity against human MCF7 cells expressing p53 after 72 hrs by celltiter-glo assay
    [PMID: 20873740]
    MCF7 IC50
    66.91 μM
    Compound: 5-Fluoruracil
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 22555152]
    MCF7 IC50
    7.08 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 24819956]
    MCF7 IC50
    7.12 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 27987485]
    MCF7 IC50
    7.12 μM
    Compound: 5-Fu
    Anticancer activity against human MCF7 cells after 72 hrs by MTT assay
    Anticancer activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 25001482]
    MCF7 IC50
    7.21 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 28759876]
    MCF7 IC50
    7.33 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 23644193]
    MCF7 IC50
    7.42 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay
    [PMID: 35797896]
    MCF7 IC50
    7.5 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 31546197]
    MCF7 IC50
    7.54 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay
    [PMID: 24077182]
    MCF7 IC50
    7.54 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 23792764]
    MCF7 IC50
    7.54 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay
    [PMID: 23353743]
    MCF7 IC50
    7.54 μM
    Compound: 5-Fu
    Antitumor activity against human MCF7 cells after 72 hrs by MTT assay
    Antitumor activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 21486694]
    MCF7 IC50
    7.61 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    [PMID: 27105028]
    MCF7 IC50
    7.67 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells incubated for 48 to 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells incubated for 48 to 72 hrs by MTT assay
    [PMID: 28395218]
    MCF7 IC50
    7.76 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 24798098]
    MCF7 IC50
    7.8 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells after 3 days by sulforhodamine B assay
    Antiproliferative activity against human MCF7 cells after 3 days by sulforhodamine B assay
    [PMID: 30248657]
    MCF7 IC50
    71.49 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 27322756]
    MCF7 CC50
    768.8 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells after 72 hrs
    Cytotoxicity against human MCF7 cells after 72 hrs
    [PMID: 18037195]
    MCF7 CC50
    768.8 μM
    Compound: 5FU
    Cytotoxicity against human MCF7 cells after 72 hrs
    Cytotoxicity against human MCF7 cells after 72 hrs
    [PMID: 17548129]
    MCF7 CC50
    768.8 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 72 hrs
    Cytotoxicity against human MCF7 cells after 72 hrs
    [PMID: 17337193]
    MCF7 IC50
    78.28 μM
    Compound: 5-FU
    Growth inhibition of human MCF7 cells after 48 hrs by WST1 assay
    Growth inhibition of human MCF7 cells after 48 hrs by WST1 assay
    [PMID: 28126436]
    MCF7 IC50
    78.3 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human MCF7 cells by MTT reduction assay
    Antiproliferative activity against human MCF7 cells by MTT reduction assay
    [PMID: 33421712]
    MCF7 IC50
    78.6 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 23067549]
    MCF7 IC50
    79.3 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    10.1039/C6MD00234J
    MCF7 GI50
    8.3 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human MCF7 cells expressing estrogen receptor after 48 hrs by SRB assay
    Antiproliferative activity against human MCF7 cells expressing estrogen receptor after 48 hrs by SRB assay
    [PMID: 20438092]
    MCF7 GI50
    8.4 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay
    Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay
    10.1007/s00044-013-0798-7
    MCF7 IC50
    8.41 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 35609396]
    MCF7 IC50
    8.5 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
    [PMID: 32987314]
    MCF7 IC50
    8.77 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    [PMID: 34302974]
    MCF7 IC50
    8.93 μM
    Compound: 5-Fu
    Cytotoxicity against human MCF7 cells assessed as inhibition of proliferation after 72 hrs by MTT assay
    Cytotoxicity against human MCF7 cells assessed as inhibition of proliferation after 72 hrs by MTT assay
    [PMID: 25180925]
    MCF7 IC50
    9.12 μM
    Compound: 5-Fu
    Anticancer activity against human MCF7 cells assessed as inhibition of proliferation after 72 hrs by MTT assay
    Anticancer activity against human MCF7 cells assessed as inhibition of proliferation after 72 hrs by MTT assay
    [PMID: 25655718]
    MCF7 IC50
    9.25 μM
    Compound: 5-Fu
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 27771599]
    MCF7 IC50
    9.49 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    [PMID: 34624825]
    MCF7 IC50
    9.56 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
    Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
    [PMID: 25959813]
    MCF7 IC50
    9.6 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs
    Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs
    [PMID: 21295381]
    MCF7 IC50
    9.67 μM
    Compound: 5-FU
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
    [PMID: 22079378]
    MCF7 IC50
    9.79 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
    [PMID: 24286761]
    MCF7 GI50
    9.9 μM
    Compound: 5-Fu
    Growth inhibition of human MCF7 cells after 48 hrs by SRB assay
    Growth inhibition of human MCF7 cells after 48 hrs by SRB assay
    [PMID: 22512908]
    MDA-MB-231 IC50
    > 20 μM
    Compound: 5-FU
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTS assay
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTS assay
    [PMID: 30472605]
    MDA-MB-231 IC50
    1.1 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by WST-8 assay
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by WST-8 assay
    [PMID: 26606140]
    MDA-MB-231 IC50
    1.6 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    [PMID: 31546197]
    MDA-MB-231 IC50
    1.8 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition by MTT assay
    Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition by MTT assay
    [PMID: 27561719]
    MDA-MB-231 IC50
    1.9 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition by MTT assay
    Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition by MTT assay
    [PMID: 27720296]
    MDA-MB-231 IC50
    10.22 μM
    Compound: 5-FU
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    [PMID: 36331508]
    MDA-MB-231 IC50
    13 μM
    Compound: 5-FU
    Anticancer activity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Anticancer activity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    [PMID: 33940466]
    MDA-MB-231 IC50
    13.65 μM
    Compound: 5-Fu
    Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
    [PMID: 23920246]
    MDA-MB-231 IC50
    13.65 μM
    Compound: 5-Fu
    Cytotoxicity against human MDA-MB-231 cells by after 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells by after 48 hrs by MTT assay
    [PMID: 22579780]
    MDA-MB-231 IC50
    15 μM
    Compound: 5-Fu
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent assay
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent assay
    [PMID: 34516133]
    MDA-MB-231 IC50
    15.74 μM
    Compound: 5-FU
    Cytotoxicity against Non-ERalpha-dependent human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against Non-ERalpha-dependent human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 33166925]
    MDA-MB-231 IC50
    16.117 μM
    Compound: 5-FU
    Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition measured after 72 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition measured after 72 hrs by MTT assay
    [PMID: 34000485]
    MDA-MB-231 IC50
    17.74 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 29133049]
    MDA-MB-231 IC50
    18.12 μM
    Compound: 5-Fu
    Cytotoxicity against human MDA-MB-231 cells after 3 days by SRB assay
    Cytotoxicity against human MDA-MB-231 cells after 3 days by SRB assay
    [PMID: 24704691]
    MDA-MB-231 IC50
    19 μM
    Compound: 5 Fluorouracil
    Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    [PMID: 27496212]
    MDA-MB-231 IC50
    2.45 μM
    Compound: FU
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    [PMID: 24941129]
    MDA-MB-231 IC50
    2.72 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against Homo sapiens (human) MDA231 cells assessed as inhibition of cell growth after 48 hr by MTT assay
    Cytotoxicity against Homo sapiens (human) MDA231 cells assessed as inhibition of cell growth after 48 hr by MTT assay
    10.1007/s00044-012-0209-5
    MDA-MB-231 IC50
    20 μM
    Compound: 5-Fu
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    10.1039/C5MD00382B
    MDA-MB-231 IC50
    21.05 μM
    Compound: 5-FU
    Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay
    [PMID: 30318440]
    MDA-MB-231 IC50
    22.53 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    [PMID: 27322756]
    MDA-MB-231 IC50
    24.5 μM
    Compound: 5-Fu
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 28759877]
    MDA-MB-231 IC50
    24.6 μM
    Compound: Fluorouracil
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    [PMID: 27128180]
    MDA-MB-231 IC50
    24.6 μM
    Compound: Fluorouracil
    Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
    [PMID: 25016234]
    MDA-MB-231 IC50
    25 μM
    Compound: 5-FU
    Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
    [PMID: 34171512]
    MDA-MB-231 IC50
    25.31 μM
    Compound: 5-FU
    Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay
    [PMID: 33894490]
    MDA-MB-231 IC50
    26.73 μM
    Compound: 5-FU
    Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
    [PMID: 35797901]
    MDA-MB-231 IC50
    29.38 μM
    Compound: 5-Fu
    Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 48 hrs by WST-1 assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 48 hrs by WST-1 assay
    [PMID: 33129590]
    MDA-MB-231 IC50
    3.5 μM
    Compound: 5-FU
    Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 24 hrs by sulforhodamine B assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 24 hrs by sulforhodamine B assay
    [PMID: 34847409]
    MDA-MB-231 IC50
    3.5 μM
    Compound: 5-FU
    Antiproliferative activity against human MDA231 cells after 24 hrs by trypan blue exclusion assay
    Antiproliferative activity against human MDA231 cells after 24 hrs by trypan blue exclusion assay
    [PMID: 20403701]
    MDA-MB-231 IC50
    31.57 μM
    Compound: 5-Fu
    Cytotoxicity against human MDA231 cells by MTT assay
    Cytotoxicity against human MDA231 cells by MTT assay
    [PMID: 22801644]
    MDA-MB-231 IC50
    35.91 μM
    Compound: 5-FU
    Cytotoxicity in human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity in human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 29657100]
    MDA-MB-231 IC50
    35.91 μM
    Compound: 5-FU
    Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 27448774]
    MDA-MB-231 IC50
    35.98 μM
    Compound: 5-FU
    Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 27614408]
    MDA-MB-231 IC50
    4.33 μM
    Compound: 5-FU
    Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
    [PMID: 28431881]
    MDA-MB-231 IC50
    4.7 μM
    Compound: 5-FU
    Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs
    Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs
    [PMID: 21295381]
    MDA-MB-231 IC50
    4.75 μM
    Compound: 5-fluoro uracil
    Cytotoxicity against human MDA-MB-231 cells incubated for 3 days by MTT assay
    Cytotoxicity against human MDA-MB-231 cells incubated for 3 days by MTT assay
    [PMID: 33152379]
    MDA-MB-231 IC50
    45.43 μM
    Compound: 5-FU
    Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
    [PMID: 27397498]
    MDA-MB-231 IC50
    45.43 μM
    Compound: 5-FU
    Anticancer activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Anticancer activity against human MDA-MB-231 cells after 48 hrs by MTT assay
    [PMID: 26413726]
    MDA-MB-231 IC50
    5 μM
    Compound: 5-FU
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
    [PMID: 27987485]
    MDA-MB-231 IC50
    5.2 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by WST8 assay
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by WST8 assay
    [PMID: 25919052]
    MDA-MB-231 IC50
    5.2 μM
    Compound: 5-FU
    Antiproliferation activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by WST-8 assay
    Antiproliferation activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by WST-8 assay
    [PMID: 27311895]
    MDA-MB-231 IC50
    5.82 μM
    Compound: 5-FU
    Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
    [PMID: 25870131]
    MDA-MB-231 IC50
    5.85 μM
    Compound: 5-Fu
    Antiproliferation activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    Antiproliferation activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay
    [PMID: 34186178]
    MDA-MB-231 IC50
    53.47 μM
    Compound: Fluorouracil
    Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay
    [PMID: 28789892]
    MDA-MB-231 GI50
    54 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against estrogen receptor deficient human MDA-MB-231 cells after 48 hrs by SRB assay
    Antiproliferative activity against estrogen receptor deficient human MDA-MB-231 cells after 48 hrs by SRB assay
    [PMID: 20438092]
    MDA-MB-231 GI50
    6.6 μM
    Compound: 5-FU
    Anticancer activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    MDA-MB-231 GI50
    6.6 μM
    Compound: 5-FU
    Growth inhibition of human MDA-MB-231 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human MDA-MB-231 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    MDA-MB-231 IC50
    66.6 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human MDA-MB-231 cells assessed as cell viability after 24 hrs
    Antiproliferative activity against human MDA-MB-231 cells assessed as cell viability after 24 hrs
    [PMID: 33139111]
    MDA-MB-231 IC50
    7.5 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 31546197]
    MDA-MB-231 IC50
    7.75 μM
    Compound: 5-FU
    Antitumor activity against human MDA-MB-231 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay
    Antitumor activity against human MDA-MB-231 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay
    [PMID: 36324491]
    MDA-MB-231 IC50
    77.28 μM
    Compound: 5-FU
    Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by WST-1 assay
    Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by WST-1 assay
    [PMID: 25466196]
    MDA-MB-231 IC50
    9.6 μM
    Compound: 5-FU
    Cytotoxicity against human MDA-MB-231 cells after 72 hrs by crystal violet staining
    Cytotoxicity against human MDA-MB-231 cells after 72 hrs by crystal violet staining
    [PMID: 22959205]
    MDA-MB-231 IC50
    9.6 μM
    Compound: 5-FU
    Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition after 144 hrs by crystal violet staining method
    Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition after 144 hrs by crystal violet staining method
    [PMID: 22450132]
    MDA-MB-231 IC50
    9.6 μM
    Compound: 5-FU
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by crystal violet staining method
    Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by crystal violet staining method
    [PMID: 22765897]
    MDA-MB-231 IC50
    9.6 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human MDA-MB-231 cells after 72 hrs
    Cytotoxicity against human MDA-MB-231 cells after 72 hrs
    [PMID: 17336074]
    MDA-MB-231 IC50
    9.89 μM
    Compound: 5-Fu
    Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 4 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 4 hrs by MTT assay
    [PMID: 32992255]
    MDA-MB-231 IC50
    93.8 μM
    Compound: 5-FU
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 31803401]
    MDA-MB-435 GI50
    0.07 μM
    Compound: 5-FU
    Anticancer activity against human MDA-MB-435 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human MDA-MB-435 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    MDA-MB-435 GI50
    0.07 μM
    Compound: 5-FU
    Growth inhibition of human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    MDA-MB-435 IC50
    25.6 μg/mL
    Compound: 5-F
    Cytotoxicity against human MDA-MB-435 cells after 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-435 cells after 48 hrs by MTT assay
    [PMID: 24342667]
    MDA-MB-435S IC50
    14.5 μM
    Compound: 5-Fu
    Cytotoxicity against human MDA-MB-435S cells after 72 hrs by MTT assay
    Cytotoxicity against human MDA-MB-435S cells after 72 hrs by MTT assay
    [PMID: 23792763]
    MDA-MB-435S IC50
    14.5 μM
    Compound: 5-FU
    Antiproliferative activity against human MDA-MB-435S cells after 72 hrs by MTT method
    Antiproliferative activity against human MDA-MB-435S cells after 72 hrs by MTT method
    [PMID: 17524655]
    MDA-MB-435S IC50
    15.19 μM
    Compound: 5-FU
    Antiproliferative activity against human MDA-MB-435S cells after 72 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-435S cells after 72 hrs by MTT assay
    [PMID: 26595184]
    MDA-MB-435S IC50
    15.2 μM
    Compound: 5-FU
    Cytotoxicity against human MDA-MB-435S cells measured after 72 hrs by MTT assay
    Cytotoxicity against human MDA-MB-435S cells measured after 72 hrs by MTT assay
    [PMID: 27537924]
    MDA-MB-453 IC50
    > 50 μM
    Compound: 5-FU
    Antiproliferative activity against human MDA-MB-453 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-453 cells after 72 hrs by MTT assay
    [PMID: 22079378]
    MDA-MB-468 IC50
    > 20 μM
    Compound: 5-Fu
    Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent assay
    Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent assay
    [PMID: 34516133]
    MDA-MB-468 IC50
    > 200 μM
    Compound: 5-FU
    Antiproliferative activity against human MDA-MB-468 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-468 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
    [PMID: 35797901]
    MDA-MB-468 IC50
    44.6 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay
    Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay
    [PMID: 29133037]
    MDA-MB-468 IC50
    44.9 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 29133037]
    MDA-MB-468 IC50
    7.5 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human MDA-MB-468 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human MDA-MB-468 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 31546197]
    MDA-MB-468 IC50
    95.69 μM
    Compound: Fluorouracil
    Cytotoxicity against human MDA-MB-468 cells after 48 hrs by MTT assay
    Cytotoxicity against human MDA-MB-468 cells after 48 hrs by MTT assay
    [PMID: 28789892]
    ME-180 IC50
    4.9 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human ME180 cells after 48 hrs by MTT assay
    Cytotoxicity against human ME180 cells after 48 hrs by MTT assay
    [PMID: 24332497]
    Melanoma cell CC50
    46.1 μM
    Compound: 5-Fu
    Cytotoxicity against human melanoma cells after 72 hrs
    Cytotoxicity against human melanoma cells after 72 hrs
    [PMID: 18037195]
    Melanoma cell CC50
    46.1 μM
    Compound: 5FU
    Cytotoxicity against human melanoma cells after 72 hrs
    Cytotoxicity against human melanoma cells after 72 hrs
    [PMID: 17548129]
    Melanoma cell CC50
    46.1 μM
    Compound: 5-FU
    Cytotoxicity against human skin melanoma cells after 72 hrs
    Cytotoxicity against human skin melanoma cells after 72 hrs
    [PMID: 17337193]
    Melanoma cell GI50
    70.6 μM
    Compound: 5-FU
    Cytotoxicity against human melanoma cells after 48 hrs by coulter counter analysis
    Cytotoxicity against human melanoma cells after 48 hrs by coulter counter analysis
    [PMID: 23683592]
    Melanoma cell GI50
    70.6 μM
    Compound: 5-FU
    Growth inhibition of human Melanoma cells after 48 hrs by coulter counter method
    Growth inhibition of human Melanoma cells after 48 hrs by coulter counter method
    [PMID: 22119151]
    Melanoma cell GI50
    70.6 μM
    Compound: 5-FU
    Cytotoxicity against human melanoma cells after 48 hrs by coulter counting
    Cytotoxicity against human melanoma cells after 48 hrs by coulter counting
    [PMID: 22056277]
    Melanoma cell GI50
    70.6 μM
    Compound: 5-FU
    Growth inhibition of human melanoma cells after 48 hrs by SRB assay
    Growth inhibition of human melanoma cells after 48 hrs by SRB assay
    [PMID: 27554444]
    Melanoma cell GI50
    70.6 μM
    Compound: 5-FU
    Cytotoxicity against human melanoma cells after 48 hrs by SRB assay
    Cytotoxicity against human melanoma cells after 48 hrs by SRB assay
    [PMID: 23994328]
    Melanoma cell GI50
    70.6 μM
    Compound: 5-fu
    Antitumor activity against human melanoma cells after 48 hrs by SRB assay
    Antitumor activity against human melanoma cells after 48 hrs by SRB assay
    [PMID: 20350811]
    Melanoma cell GI50
    70.6 μM
    Compound: 5-FU
    Cytotoxicity against human melanoma cells at 10 uM after 48 hrs
    Cytotoxicity against human melanoma cells at 10 uM after 48 hrs
    [PMID: 24469112]
    Melanoma cell GI50
    70.6 μM
    Compound: 5-FU
    Cytotoxicity against human melanoma cells after 48 hrs by sulphorhodamine B assay
    Cytotoxicity against human melanoma cells after 48 hrs by sulphorhodamine B assay
    [PMID: 23474899]
    Melanoma cell GI50
    70.6 μM
    Compound: 5-fu
    Antiproliferative activity against human melanoma cells after 48 hrs by cell counting analysis
    Antiproliferative activity against human melanoma cells after 48 hrs by cell counting analysis
    [PMID: 22995621]
    Melanoma cell GI50
    70.6 μM
    Compound: 5-FU
    Growth inhibition of human melanoma cells after 48 hrs
    Growth inhibition of human melanoma cells after 48 hrs
    [PMID: 18950904]
    MES-SA IC50
    1.1 μM
    Compound: 5-FU
    Antiproliferative activity against human MES-SA cells after 72 hrs by MTT assay
    Antiproliferative activity against human MES-SA cells after 72 hrs by MTT assay
    [PMID: 19743863]
    MeWo IC50
    8 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human MeWo cells by MTT assay
    Cytotoxicity against human MeWo cells by MTT assay
    [PMID: 29280630]
    MFE-296 IC50
    30.68 μM
    Compound: 5FU
    Cytotoxicity against human MFE296 cells incubated for 72 hrs by SRB assay
    Cytotoxicity against human MFE296 cells incubated for 72 hrs by SRB assay
    [PMID: 22867707]
    MG-63 IC50
    8 μM
    Compound: 5-FU
    Cytotoxicity against human MG63 cells after 3 days by MTT assay
    Cytotoxicity against human MG63 cells after 3 days by MTT assay
    [PMID: 21612935]
    MGC-803 IC50
    > 50 μM
    Compound: 5-Fu
    Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay
    Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay
    [PMID: 29174813]
    MGC-803 IC50
    > 50 μM
    Compound: 5-FU
    Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay
    Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay
    [PMID: 30677614]
    MGC-803 IC50
    > 50 μM
    Compound: 5-FU
    Anticancer activity against human MGC-803 cells incubated for 72 hrs by MTT assay
    Anticancer activity against human MGC-803 cells incubated for 72 hrs by MTT assay
    [PMID: 35367708]
    MGC-803 IC50
    1.25 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC803 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    [PMID: 27105028]
    MGC-803 IC50
    1.8 μg/mL
    Compound: 5-FU
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    [PMID: 29100732]
    MGC-803 IC50
    10 μM
    Compound: 5-Fu
    Anticancer activity against human MGC803 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    Anticancer activity against human MGC803 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    [PMID: 25086915]
    MGC-803 IC50
    10.14 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    [PMID: 35259487]
    MGC-803 IC50
    10.14 μM
    Compound: 5-FU
    Cytotoxicity against human MGC803 cells assessed as growth inhibition by MTT assay
    Cytotoxicity against human MGC803 cells assessed as growth inhibition by MTT assay
    [PMID: 27769034]
    MGC-803 IC50
    10.27 μM
    Compound: 5-FU
    Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth by SRB assay
    Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth by SRB assay
    [PMID: 35594653]
    MGC-803 IC50
    10.64 μM
    Compound: 5-FU
    Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by CCK8 assay
    Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by CCK8 assay
    [PMID: 27597411]
    MGC-803 IC50
    10.72 μM
    Compound: 5-Fu
    Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay
    Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay
    [PMID: 25707012]
    MGC-803 IC50
    11.34 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
    [PMID: 24835817]
    MGC-803 IC50
    12.14 μM
    Compound: 5-FU
    Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    [PMID: 34624825]
    MGC-803 IC50
    12.6 μM
    Compound: 5-FU
    Cytotoxicity against human MGC803 cells after 3 days by MTT assay
    Cytotoxicity against human MGC803 cells after 3 days by MTT assay
    [PMID: 21144621]
    MGC-803 IC50
    14 μM
    Compound: 5-FU
    Cytotoxicity against human MGC803 cells assessed as reduction in cell viability by MTT assay
    Cytotoxicity against human MGC803 cells assessed as reduction in cell viability by MTT assay
    [PMID: 31029946]
    MGC-803 IC50
    14.15 μM
    Compound: 5-FU
    Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
    [PMID: 29133051]
    MGC-803 IC50
    15.32 μM
    Compound: 5-FU
    Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay
    Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay
    [PMID: 24211021]
    MGC-803 IC50
    16.6 μM
    Compound: 5-FU
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    [PMID: 22079378]
    MGC-803 IC50
    18.5 μM
    Compound: 5-FU
    Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay
    Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay
    [PMID: 22749192]
    MGC-803 IC50
    18.63 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC-803 cells measured after 48 hrs by MTT assay
    Antiproliferative activity against human MGC-803 cells measured after 48 hrs by MTT assay
    [PMID: 32135407]
    MGC-803 IC50
    24.803 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC-803 cells by MTT assay
    Antiproliferative activity against human MGC-803 cells by MTT assay
    [PMID: 32810752]
    MGC-803 IC50
    25.54 μM
    Compound: 5-FU
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    [PMID: 29316536]
    MGC-803 IC50
    27.56 μM
    Compound: 5-FU
    Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay
    Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay
    [PMID: 37122546]
    MGC-803 IC50
    28.6 μM
    Compound: 5-FU
    Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    [PMID: 35286954]
    MGC-803 IC50
    29.15 μM
    Compound: 5-FU
    Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    [PMID: 33248852]
    MGC-803 IC50
    3.12 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    [PMID: 28165738]
    MGC-803 EC50
    3.35 μM
    Compound: 5-FU
    Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
    [PMID: 26883149]
    MGC-803 IC50
    3.38 μM
    Compound: 5-FU
    Antiproliferative activity against human MGC803 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells incubated for 72 hrs by MTT assay
    [PMID: 31404863]
    MGC-803 IC50
    3.42 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay
    Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay
    [PMID: 22405648]
    MGC-803 IC50
    3.45 μM
    Compound: 5-Fu
    Anticancer activity against human MGC803 cells after 72 hrs by MTT assay
    Anticancer activity against human MGC803 cells after 72 hrs by MTT assay
    [PMID: 25001482]
    MGC-803 IC50
    3.58 μM
    Compound: 5-Fluorouracil
    Anticancer activity against human MGC803 cells assessed as cell survival after 48 hrs by MTT assay
    Anticancer activity against human MGC803 cells assessed as cell survival after 48 hrs by MTT assay
    [PMID: 25812966]
    MGC-803 IC50
    3.68 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay
    Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay
    [PMID: 24119869]
    MGC-803 IC50
    3.71 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay
    Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay
    [PMID: 25554922]
    MGC-803 IC50
    3.79 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    [PMID: 32682202]
    MGC-803 IC50
    30.45 μM
    Compound: 5-FU
    Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay
    Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay
    [PMID: 25462253]
    MGC-803 IC50
    31.04 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    [PMID: 30142612]
    MGC-803 IC50
    34.85 μM
    Compound: 5-FU
    Antiproliferative activity against human MGC-803 cells by MTT assay
    Antiproliferative activity against human MGC-803 cells by MTT assay
    [PMID: 33109400]
    MGC-803 IC50
    39.1 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
    Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
    [PMID: 35092899]
    MGC-803 IC50
    4.55 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    [PMID: 33385852]
    MGC-803 IC50
    40.94 μM
    Compound: 5-FU
    Cytotoxicity against human MGC803 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity against human MGC803 cells assessed as cell viability after 48 hrs by MTT assay
    [PMID: 25841199]
    MGC-803 IC50
    46.93 μM
    Compound: 5-FU
    Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay
    Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay
    [PMID: 25151580]
    MGC-803 IC50
    46.93 μM
    Compound: 5-Fu
    Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay
    Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay
    [PMID: 24953029]
    MGC-803 IC50
    47.39 μM
    Compound: 5-Fu
    Cytotoxicity against human MGC803 cells after 2 days by MTT assay
    Cytotoxicity against human MGC803 cells after 2 days by MTT assay
    [PMID: 25841196]
    MGC-803 IC50
    5.81 μM
    Compound: 5-FU
    Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    [PMID: 36242987]
    MGC-803 IC50
    58 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
    [PMID: 31057737]
    MGC-803 IC50
    6.06 μM
    Compound: 5-FU
    Anticancer activity against human MGC-803 cells assessed as inhibition of cell proliferation by MTT assay
    Anticancer activity against human MGC-803 cells assessed as inhibition of cell proliferation by MTT assay
    [PMID: 36439975]
    MGC-803 IC50
    6.22 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
    Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
    [PMID: 34455358]
    MGC-803 IC50
    6.5 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human MGC803 cells by MTT assay
    Antiproliferative activity against human MGC803 cells by MTT assay
    [PMID: 31546197]
    MGC-803 IC50
    6.52 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay
    Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay
    [PMID: 32619887]
    MGC-803 IC50
    6.56 μM
    Compound: 5-FU
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    [PMID: 30108876]
    MGC-803 IC50
    6.56 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    [PMID: 28456031]
    MGC-803 IC50
    6.82 μM
    Compound: 5-FU
    Anticancer activity against human MGC-803 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Anticancer activity against human MGC-803 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    [PMID: 31577977]
    MGC-803 IC50
    6.82 μM
    Compound: 5-FU
    Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 32682200]
    MGC-803 IC50
    6.89 μM
    Compound: 5-FU
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    [PMID: 28759876]
    MGC-803 IC50
    6.92 μM
    Compound: 5-Fu
    Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by MTT assay
    [PMID: 24077182]
    MGC-803 IC50
    6.92 μM
    Compound: 5-Fu
    Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay
    Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay
    [PMID: 23792764]
    MGC-803 IC50
    62.51 μM
    Compound: 5-Fu
    Cytotoxicity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    [PMID: 34628244]
    MGC-803 IC50
    68.3 μM
    Compound: 5-Fu
    Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay
    Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay
    [PMID: 26714048]
    MGC-803 IC50
    7.01 μM
    Compound: 5-Fu
    Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by MTT assay
    [PMID: 23353743]
    MGC-803 IC50
    7.14 μM
    Compound: 5-Fu
    Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay
    Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay
    [PMID: 23644193]
    MGC-803 IC50
    7.21 μM
    Compound: 5-FU
    Cytotoxicity against human MGC803 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
    Cytotoxicity against human MGC803 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
    [PMID: 28038329]
    MGC-803 IC50
    7.21 μM
    Compound: 5-Fu
    Antitumor activity human MGC-803 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    Antitumor activity human MGC-803 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    [PMID: 36216031]
    MGC-803 IC50
    7.21 μM
    Compound: 5-FU
    Cytotoxicity against human MGC803 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human MGC803 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    [PMID: 27423479]
    MGC-803 IC50
    7.22 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    10.1039/C6MD00169F
    MGC-803 IC50
    7.35 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    [PMID: 27771599]
    MGC-803 IC50
    7.52 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC803 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    [PMID: 29113745]
    MGC-803 IC50
    7.52 μM
    Compound: 5-FU
    Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
    [PMID: 28863355]
    MGC-803 IC50
    7.52 μM
    Compound: 5-FU
    Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
    [PMID: 28838695]
    MGC-803 IC50
    7.54 μM
    Compound: 5-FU
    Cytotoxicity against human MGC-803 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    Cytotoxicity against human MGC-803 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    [PMID: 36331508]
    MGC-803 IC50
    7.69 μM
    Compound: 5-Fu
    Cytotoxicity against human MGC803 cells assessed as inhibition of proliferation after 72 hrs by MTT assay
    Cytotoxicity against human MGC803 cells assessed as inhibition of proliferation after 72 hrs by MTT assay
    [PMID: 25180925]
    MGC-803 IC50
    7.76 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC803 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
    [PMID: 25113877]
    MGC-803 IC50
    7.86 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    [PMID: 29407946]
    MGC-803 IC50
    74.39 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
    [PMID: 30108924]
    MGC-803 IC50
    8.13 μM
    Compound: 5-Fu
    Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay
    Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay
    [PMID: 24798098]
    MGC-803 IC50
    8.43 μM
    Compound: 5-Fu
    Anticancer activity against human MGC803 cells assessed as inhibition of proliferation after 72 hrs by MTT assay
    Anticancer activity against human MGC803 cells assessed as inhibition of proliferation after 72 hrs by MTT assay
    [PMID: 25655718]
    MGC-803 IC50
    8.66 μM
    Compound: 5-Fu
    Cytotoxicity against human MGC803 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    Cytotoxicity against human MGC803 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    [PMID: 30388465]
    MGC-803 IC50
    8.66 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    [PMID: 29635165]
    MGC-803 IC50
    9.05 μM
    Compound: 5-FU
    Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    [PMID: 34302974]
    MGC-803 IC50
    9.2 μM
    Compound: 5-Fu
    Cytotoxicity against human MGC803 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human MGC803 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    10.1039/C5MD00240K
    MGC-803 IC50
    9.24 μM
    Compound: 5-Fu
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
    [PMID: 29475156]
    MGC-803 IC50
    9.79 μM
    Compound: 5-FU
    Antiproliferative activity against human MGC803 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
    [PMID: 31740251]
    MGC-803 IC50
    9.79 μM
    Compound: 5-FU
    Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
    [PMID: 28763643]
    MGC-803 IC50
    93.53 μM
    Compound: 5-FU
    Cytotoxicity in human MGC-803 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity in human MGC-803 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 35085721]
    M-HeLa IC50
    62 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human HelaM cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay
    Cytotoxicity against human HelaM cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay
    [PMID: 36970146]
    MIA PaCa-2 GI50
    > 10 μM
    Compound: 5-Fu
    Growth inhibition of human MIAPaCa2 cells after 72 hrs by Alamar Blue assay
    Growth inhibition of human MIAPaCa2 cells after 72 hrs by Alamar Blue assay
    [PMID: 19406645]
    MIA PaCa-2 IC50
    10 μM
    Compound: 5-FU
    Growth inhibition of human MIAPaCa2 cells after 72 hrs by MTT assay
    Growth inhibition of human MIAPaCa2 cells after 72 hrs by MTT assay
    [PMID: 18640746]
    MIA PaCa-2 IC50
    11.45 μM
    Compound: 5-FU
    Antiproliferative activity against human MIAPaCa2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MIAPaCa2 cells after 72 hrs by MTT assay
    [PMID: 21524829]
    MIA PaCa-2 IC50
    11.67 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human MIAPaCa2 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human MIAPaCa2 cells incubated for 72 hrs by MTT assay
    [PMID: 26291038]
    MIA PaCa-2 IC50
    11.67 μM
    Compound: 5-Fluoruracil
    Antiproliferative activity against human MIAPaCa2 cells after 72 hrs by MTT assay
    Antiproliferative activity against human MIAPaCa2 cells after 72 hrs by MTT assay
    [PMID: 22555152]
    MIA PaCa-2 IC50
    14 μM
    Compound: 5-FU
    Antiproliferative activity against human MIAPaCa2 cells after 48 hrs
    Antiproliferative activity against human MIAPaCa2 cells after 48 hrs
    [PMID: 21458113]
    MIA PaCa-2 IC50
    24.267 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human MIAPaCa2 cells incubated for 24 hrs by MTT assay
    Cytotoxicity against human MIAPaCa2 cells incubated for 24 hrs by MTT assay
    [PMID: 30904782]
    MIA PaCa-2 IC50
    3.5 μg/mL
    Compound: 5-Fu
    Cytotoxicity against human MIAPaCa2 cells assessed as decrease in cell viability after 96 hrs
    Cytotoxicity against human MIAPaCa2 cells assessed as decrease in cell viability after 96 hrs
    [PMID: 29673982]
    MIA PaCa-2 GI50
    30 μM
    Compound: 5-Fu
    Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay
    Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay
    [PMID: 22512908]
    MIA PaCa-2 GI50
    30.6 nM
    Compound: 5FU
    Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay
    Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay
    [PMID: 23094992]
    MIA PaCa-2 IC50
    6.5 μM
    Compound: 5-FU
    Antiproliferative activity against human MiaPaCa2 cells after 3 days by MTT assay
    Antiproliferative activity against human MiaPaCa2 cells after 3 days by MTT assay
    [PMID: 18424155]
    MIA PaCa-2 IC50
    7.4 μM
    Compound: 5-FU
    Antiproliferative activity against human MIAPaCa2 cells after 72 hrs
    Antiproliferative activity against human MIAPaCa2 cells after 72 hrs
    [PMID: 21458113]
    MKN-28 IC50
    6.9 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human MKN28 cells by MTT assay
    Antiproliferative activity against human MKN28 cells by MTT assay
    [PMID: 31546197]
    MKN-28 IC50
    9.67 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human MKN28 cells assessed as cell survival after 48 hrs by MTT assay
    Cytotoxicity against human MKN28 cells assessed as cell survival after 48 hrs by MTT assay
    [PMID: 25506718]
    MKN-45 IC50
    21.4 μM
    Compound: 5-FU
    Cytotoxicity against human MNK45 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    Cytotoxicity against human MNK45 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    [PMID: 33740546]
    MKN-45 IC50
    3.6 x 10-1 μg/mL
    Compound: fluorouracil
    Cytotoxicity against human MKN45 cells by MTT assay
    Cytotoxicity against human MKN45 cells by MTT assay
    [PMID: 22011319]
    MKN-45 IC50
    41.73 μM
    Compound: Fluorouracil
    Cytotoxicity against human MKN45 cells after 48 hrs by MTT assay
    Cytotoxicity against human MKN45 cells after 48 hrs by MTT assay
    [PMID: 22809558]
    MKN-45 IC50
    6.9 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human MKN45 cells by MTT assay
    Antiproliferative activity against human MKN45 cells by MTT assay
    [PMID: 31546197]
    MKN-45 IC50
    8.89 μM
    Compound: 5-Fu
    Antiproliferative activity against human MKN45 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human MKN45 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    [PMID: 29113745]
    MKN-45 IC50
    8.89 μM
    Compound: 5-FU
    Antiproliferative activity against human MKN45 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MKN45 cells after 48 hrs by MTT assay
    [PMID: 28863355]
    MKN-45 IC50
    8.89 μM
    Compound: 5-FU
    Antiproliferative activity against human MKN45 cells after 48 hrs by MTT assay
    Antiproliferative activity against human MKN45 cells after 48 hrs by MTT assay
    [PMID: 28838695]
    MOLT-3 ED50
    2.14 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human TMOLT3 cells after 3 days by trypan blue exclusion technique
    Cytotoxicity against human TMOLT3 cells after 3 days by trypan blue exclusion technique
    [PMID: 1800632]
    MOLT-4 IC50
    0.03 μM
    Compound: 5-FU
    Antitumor activity against human MOLT4 cells after 24 hrs by MTT assay
    Antitumor activity against human MOLT4 cells after 24 hrs by MTT assay
    [PMID: 20211564]
    MOLT-4 GI50
    0.35 μM
    Compound: 5-FU
    Anticancer activity against human MOLT-4 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human MOLT-4 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    MOLT-4 GI50
    0.35 μM
    Compound: 5-FU
    Growth inhibition of human MOLT4 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human MOLT4 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    MOLT-4 ED50
    15.07 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human MOLT4 cells after 6 hrs by Alamar Blue assay
    Cytotoxicity against human MOLT4 cells after 6 hrs by Alamar Blue assay
    [PMID: 24020806]
    MOLT-4 IC50
    20 μM
    Compound: 5-FU
    Antiproliferative activity against human Molt4/C8 cells after 3 days by MTT assay
    Antiproliferative activity against human Molt4/C8 cells after 3 days by MTT assay
    [PMID: 18424155]
    MOLT-4 IC50
    3.2 μM
    Compound: 5-Fu
    Antiproliferative activity against human MOLT4 cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human MOLT4 cells after 48 hrs by sulforhodamine B assay
    [PMID: 22424614]
    MOLT-4 IC50
    6.2 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human MOLT4 cells incubated for 72 hrs by alamar blue assay
    Cytotoxicity against human MOLT4 cells incubated for 72 hrs by alamar blue assay
    [PMID: 28648460]
    MOLT-4 ED50
    7.7 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human MOLT4 cells by Alamar blue assay
    Cytotoxicity against human MOLT4 cells by Alamar blue assay
    [PMID: 24128077]
    Mononuclear cell line IC50
    429.8 μM
    Compound: 5-FU
    Cytotoxicity against patient-derived human mononuclear cells assessed as cell growth inhibition incubated for 72 hrs by FMCA assay
    Cytotoxicity against patient-derived human mononuclear cells assessed as cell growth inhibition incubated for 72 hrs by FMCA assay
    [PMID: 36018000]
    MRC5 GI50
    > 100 μM
    Compound: 5-FU
    Growth inhibition of human MRC5 cells after 48 hrs by SRB assay
    Growth inhibition of human MRC5 cells after 48 hrs by SRB assay
    [PMID: 28400235]
    N2a IC50
    1.2 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against mouse Neuro2a cells assessed as cell growth inhibition by MTT assay
    Cytotoxicity against mouse Neuro2a cells assessed as cell growth inhibition by MTT assay
    [PMID: 26629861]
    NCI/ADR-RES IC50
    > 100 μM
    Compound: 5-fluorouracil
    Cytotoxicity against multidrug-resistant human MCF7/ADR cells after 48 hrs by MTT assay
    Cytotoxicity against multidrug-resistant human MCF7/ADR cells after 48 hrs by MTT assay
    [PMID: 22537362]
    NCI/ADR-RES GI50
    0.31 μM
    Compound: 5-FU
    Anticancer activity against human NCI/ADR-RES cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human NCI/ADR-RES cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    NCI/ADR-RES GI50
    0.31 μM
    Compound: 5-FU
    Growth inhibition of human NCI-ADR-RES cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human NCI-ADR-RES cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    NCI/ADR-RES IC50
    512.78 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7/ADR cells after 72 hrs by MTT assay
    Cytotoxicity against human MCF7/ADR cells after 72 hrs by MTT assay
    [PMID: 30677614]
    NCI/ADR-RES IC50
    54.72 μM
    Compound: 5-FU
    Cytotoxicity against human MCF7/ADR cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human MCF7/ADR cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 31673307]
    NCI-H1299 IC50
    8.91 μM
    Compound: 5-FU
    Antiproliferative activity against human NCI-H1299 cells after 48 hrs by MTS assay
    Antiproliferative activity against human NCI-H1299 cells after 48 hrs by MTS assay
    [PMID: 28152430]
    NCI-H1650 IC50
    > 10 μM
    Compound: 5-FU
    Cytotoxicity against human NCI-H1650 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay
    Cytotoxicity against human NCI-H1650 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay
    [PMID: 32659087]
    NCI-H1650 IC50
    12.52 μM
    Compound: 5-FU
    Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay
    Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay
    [PMID: 30108876]
    NCI-H1650 IC50
    12.52 μM
    Compound: 5-Fu
    Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay
    Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay
    [PMID: 28456031]
    NCI-H1650 IC50
    14.25 μM
    Compound: 5-Fu
    Antiproliferative activity against human NCI-H1650 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human NCI-H1650 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    [PMID: 29113745]
    NCI-H1650 IC50
    14.25 μM
    Compound: 5-FU
    Antiproliferative activity against human NCI-H1650 cells after 48 hrs by MTT assay
    Antiproliferative activity against human NCI-H1650 cells after 48 hrs by MTT assay
    [PMID: 28863355]
    NCI-H1650 IC50
    14.25 μM
    Compound: 5-FU
    Antiproliferative activity against human NCI-H1650 cells after 48 hrs by MTT assay
    Antiproliferative activity against human NCI-H1650 cells after 48 hrs by MTT assay
    [PMID: 28838695]
    NCI-H1650 IC50
    14.63 μM
    Compound: 5-Fu
    Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay
    Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay
    [PMID: 29407946]
    NCI-H1975 IC50
    2.67 μM
    Compound: 5-Fu
    Antiproliferative activity against human NCI-H1975 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Antiproliferative activity against human NCI-H1975 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    [PMID: 32682202]
    NCI-H1975 IC50
    9.37 μM
    Compound: 5-FU
    Antiproliferative activity against human NCI-H1975 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Antiproliferative activity against human NCI-H1975 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    [PMID: 34302974]
    NCI-H226 GI50
    54.7 μM
    Compound: 5-FU
    Anticancer activity against human NCI-H226 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human NCI-H226 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    NCI-H226 GI50
    54.7 μM
    Compound: 5-FU
    Growth inhibition of human NCI-H226 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human NCI-H226 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    NCI-H23 GI50
    0.33 μM
    Compound: 5-FU
    Anticancer activity against human NCI-H23 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human NCI-H23 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    NCI-H23 GI50
    0.33 μM
    Compound: 5-FU
    Growth inhibition of human NCI-H23 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human NCI-H23 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    NCI-H358 IC50
    6.9 μg/mL
    Compound: 5-Fu
    Cytotoxicity against human NCI-H358 cells assessed as decrease in cell viability after 96 hrs
    Cytotoxicity against human NCI-H358 cells assessed as decrease in cell viability after 96 hrs
    [PMID: 29673982]
    NCI-H460 GI50
    0.05 μM
    Compound: 5-FU
    Anticancer activity against human NCI-H460 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human NCI-H460 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    NCI-H460 GI50
    0.05 μM
    Compound: 5-FU
    Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    NCI-H460 GI50
    0.3 μg/mL
    Compound: 5FU
    Cytotoxicity against human H460 cells assessed as growth inhibition after 48 hrs by SRB assay method
    Cytotoxicity against human H460 cells assessed as growth inhibition after 48 hrs by SRB assay method
    [PMID: 26383125]
    NCI-H460 IC50
    0.54 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability by SRB assay
    Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability by SRB assay
    [PMID: 30660827]
    NCI-H460 IC50
    11.75 μM
    Compound: 5-FU
    Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay
    Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay
    [PMID: 30318440]
    NCI-H460 IC50
    2 μM
    Compound: 5-FU
    Antitumor activity against human H460 cells after 24 hrs by MTT assay
    Antitumor activity against human H460 cells after 24 hrs by MTT assay
    [PMID: 20211564]
    NCI-H460 IC50
    2 μM
    Compound: 5-FU
    Growth inhibition of human H460 cells after 72 hrs by MTT assay
    Growth inhibition of human H460 cells after 72 hrs by MTT assay
    [PMID: 18640746]
    NCI-H460 IC50
    2.4 μM
    Compound: 5-FU
    Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay
    Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay
    [PMID: 22727445]
    NCI-H460 IC50
    2.48 μg/mL
    Compound: 5-Fluorouracil
    Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
    Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
    [PMID: 24021891]
    NCI-H460 IC50
    2.7 μM
    Compound: 5-FU
    Antiproliferative activity against human H460 cells after 24 hrs by trypan blue exclusion assay
    Antiproliferative activity against human H460 cells after 24 hrs by trypan blue exclusion assay
    [PMID: 20403701]
    NCI-H460 IC50
    23.32 μM
    Compound: 5-FU
    Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay
    Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay
    [PMID: 24211021]
    NCI-H460 IC50
    26.7 μM
    Compound: 5-FU
    Cytotoxicity against human H460 cells after 48 hrs by MTT assay
    Cytotoxicity against human H460 cells after 48 hrs by MTT assay
    [PMID: 23867385]
    NCI-H460 IC50
    29 μM
    Compound: 5-fu
    Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
    Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
    [PMID: 22304344]
    NCI-H460 IC50
    3 μM
    Compound: 5-Fluorouracil
    Cytostatic activity against human NCI-H460 cells after 72 hrs by MTT assay
    Cytostatic activity against human NCI-H460 cells after 72 hrs by MTT assay
    [PMID: 22405290]
    NCI-H460 IC50
    3 μM
    Compound: 5-FU
    Cytotoxicity against human H460 cells after 72 hrs by MTT assay
    Cytotoxicity against human H460 cells after 72 hrs by MTT assay
    [PMID: 22130132]
    NCI-H460 IC50
    35.52 μM
    Compound: 5-FU
    Cytotoxic activity against human NCI-H460 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
    Cytotoxic activity against human NCI-H460 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
    [PMID: 26706349]
    NCI-H460 IC50
    36 μM
    Compound: 5-FU
    Antiproliferative activity against human NCI-H460 cells after 48 hrs by MTT assay
    Antiproliferative activity against human NCI-H460 cells after 48 hrs by MTT assay
    [PMID: 28756264]
    NCI-H460 IC50
    36.04 μM
    Compound: 5-FU
    Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
    Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
    [PMID: 25462253]
    NCI-H460 IC50
    36.04 μM
    Compound: 5-FU
    Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
    Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
    [PMID: 24565905]
    NCI-H460 GI50
    4.1 μM
    Compound: 5FU
    Cytotoxicity against human H460 cells after 48 hrs
    Cytotoxicity against human H460 cells after 48 hrs
    [PMID: 18798609]
    NCI-H460 IC50
    44.04 μM
    Compound: 5-FU
    Cytotoxicity against human NCI-H460 cells after 3 days by MTT assay
    Cytotoxicity against human NCI-H460 cells after 3 days by MTT assay
    [PMID: 24095745]
    NCI-H460 IC50
    44.04 μM
    Compound: 5-FU
    Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
    Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
    [PMID: 25151580]
    NCI-H460 IC50
    44.04 μM
    Compound: 5-FU
    Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
    Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
    [PMID: 23988357]
    NCI-H460 IC50
    45.14 μM
    Compound: 5-Fu
    Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
    Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
    [PMID: 24953029]
    NCI-H460 IC50
    45.44 μM
    Compound: 5-FU
    Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
    Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
    [PMID: 30108826]
    NCI-H460 IC50
    45.44 μM
    Compound: 5-FU
    Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
    Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
    [PMID: 30092368]
    NCI-H460 IC50
    46.15 μM
    Compound: 5-Fu
    Cytotoxicity against human NCI-H460 cells after 2 days by MTT assay
    Cytotoxicity against human NCI-H460 cells after 2 days by MTT assay
    [PMID: 25841196]
    NCI-H460 GI50
    5.95 μM
    Compound: 5-FU
    Cytotoxicity against human NCI-H460 cells after 48 hrs by SRB assay
    Cytotoxicity against human NCI-H460 cells after 48 hrs by SRB assay
    10.1007/s00044-013-0798-7
    NCI-H460 GI50
    6.5 μM
    Compound: 5-Fu
    Growth inhibition of human NCI-H460 cells after 48 hrs by SRB assay
    Growth inhibition of human NCI-H460 cells after 48 hrs by SRB assay
    [PMID: 22512908]
    NCI-H460 IC50
    7.03 μM
    Compound: 5-Fu
    Antiproliferative activity against human NCI-H460 cells assessed as reduction in cell growth by CCK8 assay
    Antiproliferative activity against human NCI-H460 cells assessed as reduction in cell growth by CCK8 assay
    [PMID: 33964443]
    NCI-H460 IC50
    7.2 μg/mL
    Compound: 5-FU
    Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay
    Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay
    [PMID: 22647218]
    NCI-H460 IC50
    8.5 μM
    Compound: 5-FU
    Antiproliferative activity against human NCI-H460 cells after 48 h by hrs MTT assay
    Antiproliferative activity against human NCI-H460 cells after 48 h by hrs MTT assay
    [PMID: 29305189]
    NCI-H460 IC50
    9.9 μM
    Compound: 5-FU
    Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay
    Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay
    [PMID: 32659087]
    NCI-H508 IC50
    8.8 μM
    Compound: 5-FU
    Antiproliferative activity against human NCI-H508 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human NCI-H508 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 32127259]
    NCI-H522 IC50
    55.6 μM
    Compound: 5-FU
    Growth inhibition of human NCI-H522 cells after 24 hrs by MTT assay
    Growth inhibition of human NCI-H522 cells after 24 hrs by MTT assay
    [PMID: 28011220]
    NCI-H522 IC50
    56.76 μM
    Compound: 5-FU
    Cytotoxicity against human NCI-H522 cells after 24 hrs by MTT assay
    Cytotoxicity against human NCI-H522 cells after 24 hrs by MTT assay
    [PMID: 23202484]
    NCI-H522 GI50
    7.27 μM
    Compound: 5-FU
    Anticancer activity against human NCI-H522 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human NCI-H522 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    NCI-H522 GI50
    7.27 μM
    Compound: 5-FU
    Growth inhibition of human NCI-H522 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human NCI-H522 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    NCI-H522 GI50
    7.28 μM
    Compound: 5-FU
    Cytotoxicity against human NCI-H522 cells after 48 hrs by SRB assay
    Cytotoxicity against human NCI-H522 cells after 48 hrs by SRB assay
    [PMID: 22305543]
    NCI-H69 IC50
    0.28 mg/mL
    Compound: 5-Fu
    Cytotoxicity against human NCI-H69 cells after 3 days MTT assay
    Cytotoxicity against human NCI-H69 cells after 3 days MTT assay
    [PMID: 22796042]
    NCI-H69 GI50
    100 μM
    Compound: 5-Fu
    Growth inhibition of human NCI-H69 cells after 48 hrs by SRB assay
    Growth inhibition of human NCI-H69 cells after 48 hrs by SRB assay
    [PMID: 22512908]
    NCM460 EC50
    43.32 μM
    Compound: 5-FU
    Cytotoxicity against human NCM460 cells assessed as cell viability measured after 72 hrs in presence of 5-FU by MTT assay
    Cytotoxicity against human NCM460 cells assessed as cell viability measured after 72 hrs in presence of 5-FU by MTT assay
    [PMID: 34411894]
    NHDF IC50
    > 25 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human NHDF cells incubated for 72 hrs by MTS assay
    Cytotoxicity against human NHDF cells incubated for 72 hrs by MTS assay
    [PMID: 31158748]
    NHDF IC50
    14.67 μM
    Compound: 5-FU
    Antiproliferative activity against NHDF expressing p53 gene after 72 hrs by proliferative assay
    Antiproliferative activity against NHDF expressing p53 gene after 72 hrs by proliferative assay
    [PMID: 18469809]
    NHDF IC50
    30 μM
    Compound: 5-FU
    Antiproliferative activity against NHDF expressing p53 after 72 hrs by celltiter-glo assay
    Antiproliferative activity against NHDF expressing p53 after 72 hrs by celltiter-glo assay
    [PMID: 20873740]
    NHDF GI50
    62.02 nM
    Compound: 5FU
    Growth inhibition of human NHDF cells after 48 hrs by SRB assay
    Growth inhibition of human NHDF cells after 48 hrs by SRB assay
    [PMID: 23094992]
    NHDF IC50
    7.02 μM
    Compound: FUra
    Cytotoxicity against HDF assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay
    Cytotoxicity against HDF assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay
    [PMID: 27501415]
    NHDF IC50
    7.38 μM
    Compound: 5-FU
    Antiproliferative activity against NHDF after 72 hrs by MTT assay
    Antiproliferative activity against NHDF after 72 hrs by MTT assay
    [PMID: 29223098]
    NHDF IC50
    70.4 μM
    Compound: 1; 5-FU
    Cytotoxicity against NHDF assessed as reduction in cell viability measured after 48 hrs by SRB assay
    Cytotoxicity against NHDF assessed as reduction in cell viability measured after 48 hrs by SRB assay
    [PMID: 33819035]
    NIH3T3 GI50
    < 1.54 μM
    Compound: 5FU
    Cytotoxicity against BALB mouse 3T3 cells after 48 hrs
    Cytotoxicity against BALB mouse 3T3 cells after 48 hrs
    [PMID: 18798609]
    NIH3T3 IC50
    22.36 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against mouse NIH/3T3 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
    Antiproliferative activity against mouse NIH/3T3 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay
    [PMID: 25959813]
    NSCLC GI50
    > 100 μM
    Compound: 5-FU
    Growth inhibition of human NSCLC cells after 48 hrs by coulter counter method
    Growth inhibition of human NSCLC cells after 48 hrs by coulter counter method
    [PMID: 22119151]
    NSCLC GI50
    > 100 μM
    Compound: 5-FU
    Cytotoxicity against human NSCLC cells after 48 hrs by coulter counting
    Cytotoxicity against human NSCLC cells after 48 hrs by coulter counting
    [PMID: 22056277]
    NSCLC GI50
    > 100 μM
    Compound: 5-FU
    Growth inhibition of human NSCLC cells after 48 hrs
    Growth inhibition of human NSCLC cells after 48 hrs
    [PMID: 18950904]
    Ovarian cancer cell line IC50
    562.8 μM
    Compound: 5-FU
    Anticancer activity against patient-derived human Ovarian tumor cells assessed as tumor growth inhibition incubated for 72 hrs by FMCA assay
    Anticancer activity against patient-derived human Ovarian tumor cells assessed as tumor growth inhibition incubated for 72 hrs by FMCA assay
    [PMID: 36018000]
    OVCAR-3 IC50
    > 100 μM
    Compound: 5-fluorouracil
    Cytotoxicity in human OVCAR3 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity in human OVCAR3 cells assessed as cell viability after 48 hrs by MTT assay
    [PMID: 21250700]
    OVCAR-3 GI50
    0.01 μM
    Compound: 5-FU
    Anticancer activity against human OVCAR-3 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human OVCAR-3 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    OVCAR-3 GI50
    0.01 μM
    Compound: 5-FU
    Growth inhibition of human OVCAR3 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human OVCAR3 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    OVCAR-4 GI50
    4.43 μM
    Compound: 5-FU
    Anticancer activity against human OVCAR-4 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human OVCAR-4 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    OVCAR-4 GI50
    4.43 μM
    Compound: 5-FU
    Growth inhibition of human OVCAR4 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human OVCAR4 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    OVCAR-5 GI50
    10.9 μM
    Compound: 5-FU
    Anticancer activity against human OVCAR-5 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human OVCAR-5 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    OVCAR-5 GI50
    10.9 μM
    Compound: 5-FU
    Growth inhibition of human OVCAR5 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human OVCAR5 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    OVCAR-5 GI50
    20 μM
    Compound: 5-Fu
    Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay
    Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay
    [PMID: 22512908]
    OVCAR-5 GI50
    26.4 nM
    Compound: 5FU
    Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay
    Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay
    [PMID: 23094992]
    OVCAR-8 IC50
    > 100 μM
    Compound: 5-FU
    Antiproliferative activity against human p53 deficient OVCAR8 cells after 72 hrs by celltiter-glo assay
    Antiproliferative activity against human p53 deficient OVCAR8 cells after 72 hrs by celltiter-glo assay
    [PMID: 20873740]
    OVCAR-8 GI50
    1.74 μM
    Compound: 5-FU
    Anticancer activity against human OVCAR-8 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human OVCAR-8 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    OVCAR-8 GI50
    1.74 μM
    Compound: 5-FU
    Growth inhibition of human OVCAR8 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human OVCAR8 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    OVCAR-8 IC50
    96.37 μM
    Compound: 5-FU
    Antiproliferative activity against p53 deficient human OVCAR8 cells after 72 hrs by proliferative assay
    Antiproliferative activity against p53 deficient human OVCAR8 cells after 72 hrs by proliferative assay
    [PMID: 18469809]
    P388 IC50
    0.0219 mM
    Compound: 5-FU
    Cytotoxicity against Mus musculus (mouse) P388 cells assessed as growth inhibition after 72 hr by MTT assay
    Cytotoxicity against Mus musculus (mouse) P388 cells assessed as growth inhibition after 72 hr by MTT assay
    10.1007/s00044-012-0181-0
    P388 IC50
    1.7 pM
    Compound: 5-FU
    Cytotoxicity against mouse P388 cells after 72 hrs by MTT assay
    Cytotoxicity against mouse P388 cells after 72 hrs by MTT assay
    [PMID: 21640594]
    P388 IC50
    5.8 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against mouse P388 cells incubated for 72 hrs by alamar blue assay
    Cytotoxicity against mouse P388 cells incubated for 72 hrs by alamar blue assay
    [PMID: 28648460]
    P388 ED50
    6.2 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against mouse P388 cells by Alamar blue assay
    Cytotoxicity against mouse P388 cells by Alamar blue assay
    [PMID: 24128077]
    P388 IC50
    609 nM
    Compound: Fluorouracil
    Antiproliferative activity against mouse P388 cells after 48 hrs by MTT assay
    Antiproliferative activity against mouse P388 cells after 48 hrs by MTT assay
    [PMID: 2778449]
    PA-1 IC50
    39.5 μM
    Compound: 5-FU
    Growth inhibition of human PA1 cells after 24 hrs by MTT assay
    Growth inhibition of human PA1 cells after 24 hrs by MTT assay
    [PMID: 28011220]
    PA-1 IC50
    39.5 μM
    Compound: 5-FU
    Cytotoxicity against human PA1 cells after 24 hrs by MTT assay
    Cytotoxicity against human PA1 cells after 24 hrs by MTT assay
    [PMID: 23202484]
    PA-1 IC50
    5 μM
    Compound: 5-FU
    Antiproliferative activity against human PA1 cells after 48 hrs by resazurin reduction test
    Antiproliferative activity against human PA1 cells after 48 hrs by resazurin reduction test
    [PMID: 21530016]
    PA-1 IC50
    7.59 μM
    Compound: 5-FU
    Anticancer activity against human PA1 cells after 48 hrs by MTT assay
    Anticancer activity against human PA1 cells after 48 hrs by MTT assay
    [PMID: 26413726]
    PA-1 IC50
    8.51 μM
    Compound: F
    Cytotoxicity against human PA1 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human PA1 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    [PMID: 27210438]
    PANC-1 IC50
    0.4 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human PANC1 cells after 72 hrs by WST-8 assay
    Antiproliferative activity against human PANC1 cells after 72 hrs by WST-8 assay
    [PMID: 26606140]
    PANC-1 IC50
    100 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human PANC-1 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay
    Cytotoxicity against human PANC-1 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay
    [PMID: 36970146]
    PANC-1 IC50
    15 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human PANC1 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human PANC1 cells incubated for 72 hrs by MTT assay
    [PMID: 31829592]
    PANC-1 IC50
    3.7 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human PANC1 cells after 72 hrs by WST8 assay
    Antiproliferative activity against human PANC1 cells after 72 hrs by WST8 assay
    [PMID: 25919052]
    PANC-1 IC50
    3.94 μM
    Compound: 5-FU
    Cytotoxicity against human PANC1 cells by crystal violet staining
    Cytotoxicity against human PANC1 cells by crystal violet staining
    [PMID: 20930123]
    PANC-1 IC50
    4.3 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human Panc-1 cells assessed as reduction in cell growth incubated for 72 hrs by SRB assay
    Antiproliferative activity against human Panc-1 cells assessed as reduction in cell growth incubated for 72 hrs by SRB assay
    [PMID: 32007666]
    PANC-1 IC50
    47.83 μM
    Compound: 5-Fu
    Antiproliferative activity against human PANC1 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PANC1 cells after 48 hrs by MTT assay
    [PMID: 28110871]
    PANC-1 IC50
    50 μM
    Compound: 5-FU
    Cytotoxicity against human PANC1 cells assessed as inhibition of cell viability after 6 days by MTT assay
    Cytotoxicity against human PANC1 cells assessed as inhibition of cell viability after 6 days by MTT assay
    [PMID: 23360104]
    PANC-1 IC50
    50 μM
    Compound: 5-FU
    Cytotoxicity against human PANC1 cells after 72 hrs by MTT assay
    Cytotoxicity against human PANC1 cells after 72 hrs by MTT assay
    [PMID: 25124114]
    PANC-1 IC50
    54.1 μM
    Compound: 5-fluorouracil
    Cytotoxicity in human PANC1 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity in human PANC1 cells assessed as cell viability after 48 hrs by MTT assay
    [PMID: 21250700]
    PANC-1 IC50
    62.303 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human PANC1 cells incubated for 24 hrs by MTT assay
    Cytotoxicity against human PANC1 cells incubated for 24 hrs by MTT assay
    [PMID: 30904782]
    Panel NCI-60 cells GI50
    18000 μM
    Compound: 5-fluorouracil
    Growth inhibition of human Panel NCI-60 (60 carcinoma cell lines) incubated for 48 hrs by sulforhodamine B assay
    Growth inhibition of human Panel NCI-60 (60 carcinoma cell lines) incubated for 48 hrs by sulforhodamine B assay
    [PMID: 33766762]
    Panel NCI-60 cells GI50
    22.6 μM
    Compound: 5-Fluorouracil
    Anticancer activity against human Panel NCI-60 (60 carcinoma cell lines) cells assessed as cell growth inhibition incubated for 48 hrs by sulforhodamine B assay
    Anticancer activity against human Panel NCI-60 (60 carcinoma cell lines) cells assessed as cell growth inhibition incubated for 48 hrs by sulforhodamine B assay
    [PMID: 31881454]
    PaTu 8988t IC50
    2.08 μM
    Compound: 5-FU
    Cytotoxicity against human Patu-T cells by crystal violet staining
    Cytotoxicity against human Patu-T cells by crystal violet staining
    [PMID: 20930123]
    PaTu 8988t IC50
    33.2 μM
    Compound: 5-FU
    Cytotoxicity against human 5-FU-resistant Patu-T cells by crystal violet staining
    Cytotoxicity against human 5-FU-resistant Patu-T cells by crystal violet staining
    [PMID: 20930123]
    PBMC IC50
    > 40 μM
    Compound: 5-Fu
    Cytotoxicity against human PBMC assessed as reduction in cell growth after 72 hrs by MTT assay
    Cytotoxicity against human PBMC assessed as reduction in cell growth after 72 hrs by MTT assay
    [PMID: 31883693]
    PBMC IC50
    > 50 μM
    Compound: 5-Fu
    Cytotoxicity against human PBMC cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity against human PBMC cells assessed as cell viability after 48 hrs by MTT assay
    [PMID: 31877536]
    PBMC IC50
    > 50 μM
    Compound: 5-Fu
    Cytotoxicity against human PBMC assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human PBMC assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 31202992]
    PC-3 IC50
    > 30 μM
    Compound: 5-FU
    Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 29133061]
    PC-3 IC50
    0.016 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    [PMID: 19423198]
    PC-3 IC50
    0.03 μM
    Compound: 5-FU
    Cytotoxicity against human PC3 cells assessed as growth inhibition after 24 hrs by sulforhodamine B assay
    Cytotoxicity against human PC3 cells assessed as growth inhibition after 24 hrs by sulforhodamine B assay
    [PMID: 27156770]
    PC-3 IC50
    0.53 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    [PMID: 29254641]
    PC-3 IC50
    1.2 mM
    Compound: 5-FU
    Cytotoxicity against human PC3 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    [PMID: 27847140]
    PC-3 IC50
    1.2 μM
    Compound: 5-FU
    Cytotoxicity in human PC3 cells incubated for 48 hrs by MTT assay
    Cytotoxicity in human PC3 cells incubated for 48 hrs by MTT assay
    [PMID: 28923381]
    PC-3 IC50
    1.2 μM
    Compound: 5-FU
    Cytotoxicity against human PC3 cells after 48 hrs by MTT assay
    Cytotoxicity against human PC3 cells after 48 hrs by MTT assay
    [PMID: 28431881]
    PC-3 IC50
    1.44 μM
    Compound: 5-FU
    Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay
    [PMID: 26735909]
    PC-3 IC50
    1.6 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    [PMID: 31546197]
    PC-3 IC50
    1.8 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human PC3 cells assessed as cell growth inhibition by MTT assay
    Cytotoxicity against human PC3 cells assessed as cell growth inhibition by MTT assay
    [PMID: 27720296]
    PC-3 IC50
    10.3 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human PC-3 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay
    Cytotoxicity against human PC-3 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay
    [PMID: 36970146]
    PC-3 IC50
    10.4 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
    Antiproliferative activity against human PC-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
    [PMID: 34455358]
    PC-3 GI50
    10.45 nM
    Compound: 5FU
    Growth inhibition of human PC3 cells after 48 hrs by SRB assay
    Growth inhibition of human PC3 cells after 48 hrs by SRB assay
    [PMID: 23094992]
    PC-3 IC50
    106.26 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human PC-3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC-3 cells after 48 hrs by MTT assay
    [PMID: 27322756]
    PC-3 GI50
    11.7 μM
    Compound: 5-Fluorouracil
    Growth inhibition of human PC3 cells after 48 hrs by SRB assay
    Growth inhibition of human PC3 cells after 48 hrs by SRB assay
    [PMID: 28898082]
    PC-3 IC50
    12 μM
    Compound: 5-fluorouracil
    Anticancer activity against human PC3 cells assessed as cell viability after 48 hrs by SRB assay
    Anticancer activity against human PC3 cells assessed as cell viability after 48 hrs by SRB assay
    [PMID: 21074444]
    PC-3 IC50
    12 μM
    Compound: 5-FU
    Antiproliferative activity against prostate cancer PC-3 cell line using sulforhodamine B(SRB) assay
    Antiproliferative activity against prostate cancer PC-3 cell line using sulforhodamine B(SRB) assay
    [PMID: 15801848]
    PC-3 IC50
    12 μM
    Compound: 5-FU
    Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay
    [PMID: 24956552]
    PC-3 GI50
    12 μM
    Compound: 5FU
    Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay
    [PMID: 21489802]
    PC-3 IC50
    12 μM
    Compound: 5-FU
    Antiproliferative activity against human prostate cancer PC-3 cell line by sulforhodamine B assay
    Antiproliferative activity against human prostate cancer PC-3 cell line by sulforhodamine B assay
    [PMID: 16005217]
    PC-3 IC50
    12 μM
    Compound: 5-FU
    Antiproliferative activity was evaluated against human prostate PC-3 cancer cell lines using the sulforhodamine B (STB) assay
    Antiproliferative activity was evaluated against human prostate PC-3 cancer cell lines using the sulforhodamine B (STB) assay
    [PMID: 15454213]
    PC-3 IC50
    12.23 μM
    Compound: 5-FU
    Cytotoxicity against human PC3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    10.1039/C6MD00061D
    PC-3 IC50
    12.33 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    [PMID: 29635165]
    PC-3 IC50
    12.87 μM
    Compound: 5-FU
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    [PMID: 28763643]
    PC-3 IC50
    13.3 μM
    Compound: 5 Fluorouracil
    Cytotoxicity against human PC3 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as decrease in cell viability after 24 hrs by MTT assay
    [PMID: 27496212]
    PC-3 IC50
    13.7 μM
    Compound: 5-Fu
    Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 28759877]
    PC-3 IC50
    13.77 μM
    Compound: 5-FU
    Antiproliferative activity against human PC3 cells expressing p53 gene after 72 hrs by proliferative assay
    Antiproliferative activity against human PC3 cells expressing p53 gene after 72 hrs by proliferative assay
    [PMID: 18469809]
    PC-3 GI50
    14.6 μM
    Compound: 5FU
    Cytotoxicity against human PC3 cells after 48 hrs
    Cytotoxicity against human PC3 cells after 48 hrs
    [PMID: 18798609]
    PC-3 IC50
    15.12 μM
    Compound: 5-Fu
    Antitumor activity against human PC-3 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    Antitumor activity against human PC-3 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    [PMID: 36216031]
    PC-3 IC50
    15.31 μM
    Compound: 5-Fu
    Cytotoxic activity against human PC3 cells assessed as reduction in cell viability after 72 hrs by SRB assay
    Cytotoxic activity against human PC3 cells assessed as reduction in cell viability after 72 hrs by SRB assay
    [PMID: 28011223]
    PC-3 IC50
    15.69 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human PC3 after 48 hrs by MTT assay
    Cytotoxicity against human PC3 after 48 hrs by MTT assay
    [PMID: 21486698]
    PC-3 IC50
    17.31 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC-3 cells measured after 48 hrs by MTT assay
    Antiproliferative activity against human PC-3 cells measured after 48 hrs by MTT assay
    [PMID: 32135407]
    PC-3 IC50
    18.4 μM
    Compound: 5-FU
    Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 32682200]
    PC-3 IC50
    18.42 μM
    Compound: 5-FU
    Anticancer activity against human PC-3 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Anticancer activity against human PC-3 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    [PMID: 31577977]
    PC-3 IC50
    19.87 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 29133049]
    PC-3 IC50
    2.1 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay
    [PMID: 22424614]
    PC-3 IC50
    2.2 μM
    Compound: 5-FU
    Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay
    [PMID: 24910974]
    PC-3 IC50
    2.2 μM
    Compound: 5-FU
    Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23501113]
    PC-3 IC50
    2.2 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay
    Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay
    [PMID: 26222449]
    PC-3 GI50
    2.36 μM
    Compound: 5-FU
    Anticancer activity against human PC-3 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human PC-3 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    PC-3 GI50
    2.36 μM
    Compound: 5-FU
    Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    PC-3 IC50
    2.42 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 31546197]
    PC-3 IC50
    2.48 μg/mL
    Compound: 5-Fluorouracil
    Cytotoxicity against human PC3 cells after 48 hrs by MTT assay
    Cytotoxicity against human PC3 cells after 48 hrs by MTT assay
    [PMID: 20800480]
    PC-3 IC50
    2.5 μM
    Compound: 5-FU
    Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    [PMID: 36242987]
    PC-3 IC50
    2.76 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    [PMID: 27092413]
    PC-3 IC50
    2.88 μM
    Compound: 5-fluoro uracil
    Cytotoxicity against human PC-3 cells incubated for 3 days by MTT assay
    Cytotoxicity against human PC-3 cells incubated for 3 days by MTT assay
    [PMID: 33152379]
    PC-3 IC50
    20.42 μM
    Compound: 5-FU
    Antiproliferative activity against human PC3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
    [PMID: 31740251]
    PC-3 IC50
    20.45 μM
    Compound: 5-FU
    Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 30921757]
    PC-3 GI50
    21 μM
    Compound: 5-Fu
    Growth inhibition of human PC3 cells after 48 hrs by SRB assay
    Growth inhibition of human PC3 cells after 48 hrs by SRB assay
    [PMID: 22512908]
    PC-3 IC50
    22.02 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC3 cells by MTT assay
    Antiproliferative activity against human PC3 cells by MTT assay
    [PMID: 29131616]
    PC-3 IC50
    22.63 μM
    Compound: 5-Fu
    Cytotoxicity against human PC3 cells after 48 hrs by MTT assay
    Cytotoxicity against human PC3 cells after 48 hrs by MTT assay
    [PMID: 26363869]
    PC-3 IC50
    23.1 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    [PMID: 30527868]
    PC-3 IC50
    23.86 μM
    Compound: 5-FU
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    [PMID: 29524728]
    PC-3 IC50
    23.86 μM
    Compound: 5-FU
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    [PMID: 29407983]
    PC-3 IC50
    23.94 μM
    Compound: 5-FU
    Antiproliferative activity against human PC3 cells treated for 24 hrs measured after 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells treated for 24 hrs measured after 72 hrs by MTT assay
    [PMID: 29037951]
    PC-3 IC50
    24.3 μM
    Compound: 5-FU
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    [PMID: 28494251]
    PC-3 IC50
    24.33 μM
    Compound: 5-FU
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    [PMID: 28458133]
    PC-3 IC50
    24.76 μM
    Compound: 5-Fu
    Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay
    [PMID: 24077182]
    PC-3 IC50
    24.76 μM
    Compound: 5-Fu
    Cytotoxicity against human PC3 cells after 72 hrs by MTT assay
    Cytotoxicity against human PC3 cells after 72 hrs by MTT assay
    [PMID: 23792764]
    PC-3 IC50
    27.07 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC3 cells expressing SKP2 after 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells expressing SKP2 after 72 hrs by MTT assay
    [PMID: 23735281]
    PC-3 IC50
    27.07 μM
    Compound: 5-Fu
    Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay
    [PMID: 23353743]
    PC-3 IC50
    27.61 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    [PMID: 29407946]
    PC-3 IC50
    27.64 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC-3 cells assessed as inhibition of cell proliferation by MTT assay
    Antiproliferative activity against human PC-3 cells assessed as inhibition of cell proliferation by MTT assay
    [PMID: 36336316]
    PC-3 IC50
    29.3 μM
    Compound: 5-Fu
    Antitumor activity against human PC3 cells after 72 hrs by MTT assay
    Antitumor activity against human PC3 cells after 72 hrs by MTT assay
    [PMID: 21486694]
    PC-3 IC50
    29.31 μM
    Compound: 5-FU
    Cytotoxicity against human PC3 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as inhibition of cell viability after 48 hrs by MTT assay
    [PMID: 28038329]
    PC-3 IC50
    30 μM
    Compound: 5-FU
    Antiproliferative activity against human p53 deficient PC3 cells after 72 hrs by celltiter-glo assay
    Antiproliferative activity against human p53 deficient PC3 cells after 72 hrs by celltiter-glo assay
    [PMID: 20873740]
    PC-3 IC50
    31.44 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC3 cells expressing PCDNA after 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells expressing PCDNA after 72 hrs by MTT assay
    [PMID: 23735281]
    PC-3 IC50
    32.87 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability by MTT assay
    Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability by MTT assay
    [PMID: 34715305]
    PC-3 IC50
    35.75 μM
    Compound: 5-Fu
    Cytotoxicity against human PC3 cells by MTT assay
    Cytotoxicity against human PC3 cells by MTT assay
    [PMID: 22801644]
    PC-3 IC50
    38.61 μM
    Compound: 5-FU
    Antiproliferative activity against human PC3 cells incubated for 48 to 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells incubated for 48 to 72 hrs by MTT assay
    [PMID: 28395218]
    PC-3 GI50
    4.1 μM
    Compound: 5-FU
    Growth inhibition of human PC3 cells measured after 72 hrs by MTT assay
    Growth inhibition of human PC3 cells measured after 72 hrs by MTT assay
    [PMID: 27504537]
    PC-3 IC50
    4.68 μM
    Compound: 5-Fu
    Cytotoxicity against human PC3 cells after 72 hrs by MTT assay
    Cytotoxicity against human PC3 cells after 72 hrs by MTT assay
    [PMID: 24798098]
    PC-3 IC50
    4.75 μM
    Compound: 5-FU
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    [PMID: 29133051]
    PC-3 IC50
    4.9 μM
    Compound: 5-FU
    Antiproliferative activity against human PC3 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay
    Antiproliferative activity against human PC3 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay
    [PMID: 26731300]
    PC-3 IC50
    42.5 μM
    Compound: 5-FU
    Cytotoxicity against human PC3 cells measured after 72 hrs by MTT assay
    Cytotoxicity against human PC3 cells measured after 72 hrs by MTT assay
    [PMID: 27537924]
    PC-3 IC50
    42.5 μM
    Compound: 5-FU
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    [PMID: 26595184]
    PC-3 IC50
    45.32 μM
    Compound: 5-FU
    Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 27614408]
    PC-3 IC50
    46 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    10.1039/C5MD00382B
    PC-3 IC50
    49.1 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    [PMID: 30737134]
    PC-3 IC50
    5.32 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay
    [PMID: 32619887]
    PC-3 IC50
    57.04 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC3 cells measured after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells measured after 48 hrs by MTT assay
    [PMID: 27287368]
    PC-3 IC50
    6.23 μM
    Compound: 5-FU
    Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay
    [PMID: 34302974]
    PC-3 IC50
    6.27 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
    [PMID: 29475156]
    PC-3 IC50
    6.8 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability measured for 24 hrs
    Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability measured for 24 hrs
    [PMID: 31945642]
    PC-3 IC50
    63.8 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human PC3 cells after 24 hrs by MTT assay
    Cytotoxicity against human PC3 cells after 24 hrs by MTT assay
    [PMID: 31401008]
    PC-3 IC50
    68.28 μM
    Compound: 5-FU
    Anticancer activity against human PC3 cells after 48 hrs by MTT assay
    Anticancer activity against human PC3 cells after 48 hrs by MTT assay
    [PMID: 26413726]
    PC-3 IC50
    72.07 μM
    Compound: 5-FU
    Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay
    [PMID: 27448774]
    PC-3 IC50
    8.41 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    [PMID: 35259487]
    PC-3 IC50
    8.45 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay
    [PMID: 29958763]
    PC-3 IC50
    9.09 μM
    Compound: 5-FU
    Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay
    Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay
    [PMID: 35290844]
    PC-3 IC50
    9.5 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human PC-3 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay
    Cytotoxicity against human PC-3 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay
    [PMID: 33799070]
    PC-3M IC50
    22.63 μM
    Compound: Fluorouracil
    Cytotoxicity against human PC3M cells after 48 hrs by MTT assay
    Cytotoxicity against human PC3M cells after 48 hrs by MTT assay
    [PMID: 22809558]
    PC-9 IC50
    > 10 μM
    Compound: 5-FU
    Cytotoxicity against human PC-9 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay
    Cytotoxicity against human PC-9 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay
    [PMID: 32659087]
    PC-9 IC50
    1.99 μM
    Compound: 5-FU
    Cytotoxicity against human PC9 cells assessed as growth inhibition by MTT assay
    Cytotoxicity against human PC9 cells assessed as growth inhibition by MTT assay
    [PMID: 27769034]
    PC-9 IC50
    23.47 μM
    Compound: 5-FU
    Cytotoxicity against human PC9 cells after 48 hrs by MTT assay
    Cytotoxicity against human PC9 cells after 48 hrs by MTT assay
    [PMID: 22483608]
    PC-9 IC50
    3.25 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC-9 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Antiproliferative activity against human PC-9 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    [PMID: 32682202]
    PC-9 IC50
    4.12 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC9 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay
    Antiproliferative activity against human PC9 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay
    [PMID: 32619887]
    PC-9 IC50
    6.52 μM
    Compound: 5-Fu
    Antiproliferative activity against human PC-9 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Antiproliferative activity against human PC-9 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    [PMID: 33385852]
    PLC IC50
    116.8 μM
    Compound: 5-Fu
    Antiproliferative activity against human PLC cells after 48 hrs by MTT assay
    Antiproliferative activity against human PLC cells after 48 hrs by MTT assay
    [PMID: 30737134]
    PLC-PRF-5 IC50
    2.8 μM
    Compound: Fluorouracil
    Cytotoxicity against human PLC/PRF/5 cells assessed as reduction in cell viability by MTT assay
    Cytotoxicity against human PLC/PRF/5 cells assessed as reduction in cell viability by MTT assay
    [PMID: 31013087]
    PLC-PRF-5 IC50
    22.81 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human PLC/PRF/5 cells in presence of ubenimex after 48 hrs by MTT assay
    Antiproliferative activity against human PLC/PRF/5 cells in presence of ubenimex after 48 hrs by MTT assay
    [PMID: 29202398]
    PLC-PRF-5 IC50
    35.66 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human PLC/PRF/5 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PLC/PRF/5 cells after 48 hrs by MTT assay
    [PMID: 29202398]
    PLC-PRF-5 IC50
    38.35 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human PLC-PRF-5 cells after 48 hrs by MTT assay
    Antiproliferative activity against human PLC-PRF-5 cells after 48 hrs by MTT assay
    [PMID: 27322756]
    PPC-1 IC50
    6.4 μM
    Compound: 5-FU
    Antiproliferative activity against prostate cancer PPC-1 cell line using sulforhodamine B(SRB) assay
    Antiproliferative activity against prostate cancer PPC-1 cell line using sulforhodamine B(SRB) assay
    [PMID: 15801848]
    PPC-1 IC50
    6.4 μM
    Compound: 5-FU
    Antiproliferative activity against human prostate cancer PPC-1 cell line by sulforhodamine B assay
    Antiproliferative activity against human prostate cancer PPC-1 cell line by sulforhodamine B assay
    [PMID: 16005217]
    PSN1 IC50
    4.4 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human PSN1 cells after 72 hrs by WST8 assay
    Antiproliferative activity against human PSN1 cells after 72 hrs by WST8 assay
    [PMID: 25919052]
    PSN1 IC50
    8.7 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human PSN1 cells after 72 hrs by WST-8 assay
    Antiproliferative activity against human PSN1 cells after 72 hrs by WST-8 assay
    [PMID: 26606140]
    QGY-7703 IC50
    14.2 μM
    Compound: 5-Fu
    Antiproliferative activity against human QGY7703 cells after 24 hrs by CCK-8 assay
    Antiproliferative activity against human QGY7703 cells after 24 hrs by CCK-8 assay
    [PMID: 29499490]
    QGY-7703 IC50
    15.66 μM
    Compound: 5-Fu
    Cytotoxicity against human QGY7703 cells after 48 hrs by CCK-8 assay
    Cytotoxicity against human QGY7703 cells after 48 hrs by CCK-8 assay
    [PMID: 24013415]
    RKO IC50
    > 10 μM
    Compound: 5-FU
    Cytotoxicity against human RKO cells after 24 hrs by MTT assay
    Cytotoxicity against human RKO cells after 24 hrs by MTT assay
    [PMID: 32223193]
    RKO IC50
    > 50 μM
    Compound: 5-FU
    Anticancer activity against human RKO cells assessed as inhibition of cell growth after 24 hrs by MTT assay
    Anticancer activity against human RKO cells assessed as inhibition of cell growth after 24 hrs by MTT assay
    [PMID: 26922233]
    RKO IC50
    10.09 μM
    Compound: 5-FU
    Antitumor activity against human RKO cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    Antitumor activity against human RKO cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    [PMID: 35777102]
    RKO IC50
    10.2 μM
    Compound: 5-FU
    Growth inhibition of human RKO cells after 48 hrs by CCK-8 assay
    Growth inhibition of human RKO cells after 48 hrs by CCK-8 assay
    [PMID: 30106289]
    RKO IC50
    12.71 μM
    Compound: 5-FU
    Anticancer activity against human RKO cells assessed as inhibition of cell proliferation by MTT assay
    Anticancer activity against human RKO cells assessed as inhibition of cell proliferation by MTT assay
    [PMID: 36439975]
    RKO IC50
    2.9 μM
    Compound: 5-FU
    Antiproliferative activity against human RKO cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human RKO cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 32127259]
    RKO IC50
    4.39 μM
    Compound: 5-Fu
    Cytotoxicity against human RKO cells after 3 days by SRB assay
    Cytotoxicity against human RKO cells after 3 days by SRB assay
    [PMID: 24704691]
    RKO IC50
    41.1 μM
    Compound: 5-FU
    Anticancer activity against human RKO cells assessed as inhibition of cell growth after 48 hrs by MTT assay
    Anticancer activity against human RKO cells assessed as inhibition of cell growth after 48 hrs by MTT assay
    [PMID: 26922233]
    RKO IC50
    6.8 μM
    Compound: 5-FU
    Anticancer activity against human RKO cells assessed as inhibition of cell growth after 72 hrs by MTT assay
    Anticancer activity against human RKO cells assessed as inhibition of cell growth after 72 hrs by MTT assay
    [PMID: 26922233]
    RL IC50
    3.2 μM
    Compound: 5-FU
    Antiproliferative activity against human RL cells after 72 hrs by MTT assay
    Antiproliferative activity against human RL cells after 72 hrs by MTT assay
    [PMID: 19743863]
    RPMI-8226 GI50
    0.04 μM
    Compound: 5-FU
    Anticancer activity against human RPMI-8226 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human RPMI-8226 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    RPMI-8226 GI50
    0.04 μM
    Compound: 5-FU
    Growth inhibition of human RPMI8226 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human RPMI8226 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    RPMI-8226 IC50
    3.55 μM
    Compound: 5-Fluorouracil
    Antileukemic activity against human RPMI8226 cells assessed as inhibition of tumor growth after 24 hrs
    Antileukemic activity against human RPMI8226 cells assessed as inhibition of tumor growth after 24 hrs
    [PMID: 24657568]
    RXF 393 GI50
    2.61 μM
    Compound: 5-FU
    Anticancer activity against human RXF 393 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human RXF 393 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    RXF 393 GI50
    2.61 μM
    Compound: 5-FU
    Growth inhibition of human RXF393 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human RXF393 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    RXF 393 IC50
    28.23 μM
    Compound: 5-FU
    Cytotoxicity against human RXF 393 cells assessed as inhibition of cell viability incubated for 72 hrs under hypoxia condition by MTT assay
    Cytotoxicity against human RXF 393 cells assessed as inhibition of cell viability incubated for 72 hrs under hypoxia condition by MTT assay
    [PMID: 35182815]
    SCC-9 IC50
    12.7 μg/mL
    Compound: 5-FU
    Antiproliferative activity against human SCC-9 cells assessed as cell viability measured after 72 hrs by MTT assay
    Antiproliferative activity against human SCC-9 cells assessed as cell viability measured after 72 hrs by MTT assay
    [PMID: 34463097]
    SF-268 IC50
    > 100 μM
    Compound: 5-FU
    Antiproliferative activity against human p53 deficient SF268 cells after 72 hrs by celltiter-glo assay
    Antiproliferative activity against human p53 deficient SF268 cells after 72 hrs by celltiter-glo assay
    [PMID: 20873740]
    SF-268 GI50
    1.62 μM
    Compound: 5-FU
    Anticancer activity against human SF-268 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human SF-268 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    SF-268 GI50
    1.62 μM
    Compound: 5-FU
    Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    SF-268 GI50
    49.21 μM
    Compound: 5-FU
    Cytotoxicity against human SF268 cells after 48 hrs by SRB assay
    Cytotoxicity against human SF268 cells after 48 hrs by SRB assay
    10.1007/s00044-013-0798-7
    SF-268 IC50
    87.96 μM
    Compound: 5-FU
    Antiproliferative activity against p53 deficient human SF268 cells after 72 hrs
    Antiproliferative activity against p53 deficient human SF268 cells after 72 hrs
    [PMID: 18469809]
    SF-295 GI50
    0.22 μM
    Compound: 5-FU
    Growth inhibition of human SF295 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human SF295 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    SF-295 GI50
    76 μM
    Compound: 5-Fu
    Growth inhibition of human SF295 cells after 48 hrs by SRB assay
    Growth inhibition of human SF295 cells after 48 hrs by SRB assay
    [PMID: 22512908]
    SF-539 GI50
    0.06 μM
    Compound: 5-FU
    Anticancer activity against human SF-539 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human SF-539 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    SF-539 GI50
    0.06 μM
    Compound: 5-FU
    Growth inhibition of human SF539 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human SF539 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    SF-539 IC50
    43 μM
    Compound: 5-FU
    Antiproliferative activity against human SF539 cells expressing p53 after 72 hrs by celltiter-glo assay
    Antiproliferative activity against human SF539 cells expressing p53 after 72 hrs by celltiter-glo assay
    [PMID: 20873740]
    SF-539 IC50
    50.09 μM
    Compound: 5-FU
    Antiproliferative activity against human SF539 cells expressing p53 gene after 72 hrs by proliferative assay
    Antiproliferative activity against human SF539 cells expressing p53 gene after 72 hrs by proliferative assay
    [PMID: 18469809]
    SGC-7901 IC50
    > 30 μM
    Compound: 5-FU
    Antiproliferative activity against human SGC-7901 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Antiproliferative activity against human SGC-7901 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    [PMID: 33248852]
    SGC-7901 IC50
    0.58 μg/mL
    Compound: 5-FU
    Cytotoxicity against Homo sapiens (human) SGC7901 cells by MTT assay
    Cytotoxicity against Homo sapiens (human) SGC7901 cells by MTT assay
    10.1007/s00044-009-9193-9
    SGC-7901 IC50
    0.86 μM
    Compound: 5-Fu
    Cytotoxicity against human SGC7901 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
    Cytotoxicity against human SGC7901 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
    10.1039/C4MD00209A
    SGC-7901 IC50
    10.98 μM
    Compound: 5-FU
    Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay
    Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay
    [PMID: 29133051]
    SGC-7901 IC50
    11.9 μM
    Compound: 5-FU
    Cytotoxicity against human SGC7901 cells measured after 72 hrs by MTT assay
    Cytotoxicity against human SGC7901 cells measured after 72 hrs by MTT assay
    [PMID: 27537924]
    SGC-7901 IC50
    11.9 μM
    Compound: 5-FU
    Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay
    Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay
    [PMID: 26595184]
    SGC-7901 IC50
    11.96 μM
    Compound: 5-FU
    Cytotoxicity against human SGC7901 assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human SGC7901 assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 30709651]
    SGC-7901 IC50
    12 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human SGC7901 cells after 6 days by MTT assay
    Cytotoxicity against human SGC7901 cells after 6 days by MTT assay
    [PMID: 29786436]
    SGC-7901 IC50
    13.25 μM
    Compound: 5-FU
    Antiproliferative activity against human SGC7901 cells incubated for 48 to 72 hrs by MTT assay
    Antiproliferative activity against human SGC7901 cells incubated for 48 to 72 hrs by MTT assay
    [PMID: 28395218]
    SGC-7901 IC50
    14.49 μM
    Compound: 5-Fu
    Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay
    Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay
    [PMID: 22687745]
    SGC-7901 IC50
    16.03 μg/mL
    Compound: 5-fluorouracil
    Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay
    Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay
    [PMID: 28988624]
    SGC-7901 IC50
    19.84 μM
    Compound: 5-FU
    Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay
    Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay
    [PMID: 29635169]
    SGC-7901 IC50
    2.19 μM
    Compound: 5-FU
    Cytotoxicity against Homo sapiens (human) SGC7901 cells by MTT assay
    Cytotoxicity against Homo sapiens (human) SGC7901 cells by MTT assay
    10.1007/s00044-010-9395-1
    SGC-7901 IC50
    2.95 μM
    Compound: 5-FU
    Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay
    Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay
    [PMID: 20494492]
    SGC-7901 IC50
    2.96 μM
    Compound: 5-FU
    Antiproliferative activity against human SGC7901 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human SGC7901 cells incubated for 72 hrs by MTT assay
    [PMID: 31404863]
    SGC-7901 IC50
    21 μM
    Compound: 5-FU
    Cytotoxicity against human SGC7901 cells assessed as reduction in cell viability by MTT assay
    Cytotoxicity against human SGC7901 cells assessed as reduction in cell viability by MTT assay
    [PMID: 31029946]
    SGC-7901 IC50
    28.5 μM
    Compound: 5-Fu
    Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay
    Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay
    [PMID: 23279864]
    SGC-7901 IC50
    28.9 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay
    Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay
    [PMID: 23490159]
    SGC-7901 IC50
    29.19 μM
    Compound: 5-Fu
    Cytotoxicity against Homo sapiens (human) SGC7901 cells after 72 hr by MTT assay
    Cytotoxicity against Homo sapiens (human) SGC7901 cells after 72 hr by MTT assay
    10.1007/s00044-011-9549-9
    SGC-7901 IC50
    31.46 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human SGC7901 after 48 hrs by MTT assay
    Cytotoxicity against human SGC7901 after 48 hrs by MTT assay
    [PMID: 21486698]
    SGC-7901 IC50
    34.4 μM
    Compound: 5-FU
    Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay
    Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay
    [PMID: 29232583]
    SGC-7901 IC50
    36.4 μM
    Compound: 5-FU
    Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay
    Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay
    [PMID: 30108895]
    SGC-7901 IC50
    46.35 μM
    Compound: 5-Fluorouracil
    Anticancer activity against human SGC7901 cells assessed as cell survival measured after 48 hrs by MTT assay
    Anticancer activity against human SGC7901 cells assessed as cell survival measured after 48 hrs by MTT assay
    [PMID: 23312949]
    SGC-7901 IC50
    5.54 μM
    Compound: 5-FU
    Anticancer activity against human SGC-7901 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Anticancer activity against human SGC-7901 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    [PMID: 31577977]
    SGC-7901 IC50
    53.58 μM
    Compound: 5-FU
    Cytotoxicity against human SGC7901 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human SGC7901 cells assessed as growth inhibition after 72 hrs by MTT assay
    [PMID: 30826506]
    SGC-7901 IC50
    53.58 μM
    Compound: 5-FU
    Cytotoxicity against human SGC-7901 cells by MTT assay
    Cytotoxicity against human SGC-7901 cells by MTT assay
    [PMID: 33831559]
    SGC-7901 IC50
    56.12 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human SGC7901 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
    Cytotoxicity against human SGC7901 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
    [PMID: 27503679]
    SGC-7901 IC50
    59.9 μM
    Compound: 5-FU
    Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay
    Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay
    [PMID: 25164762]
    SGC-7901 IC50
    6.04 μM
    Compound: 5-Fu
    Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay
    Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay
    [PMID: 23920246]
    SGC-7901 IC50
    6.04 μM
    Compound: 5-Fu
    Cytotoxicity against human SGC7901 cells by after 48 hrs by MTT assay
    Cytotoxicity against human SGC7901 cells by after 48 hrs by MTT assay
    [PMID: 22579780]
    SGC-7901 IC50
    6.12 μM
    Compound: 5-Fluorouracil
    Anticancer activity against human SGC7901 cells assessed as cell survival after 48 hrs by MTT assay
    Anticancer activity against human SGC7901 cells assessed as cell survival after 48 hrs by MTT assay
    [PMID: 25812966]
    SGC-7901 IC50
    6.3 μM
    Compound: 5-FU
    Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay
    Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay
    [PMID: 22727445]
    SGC-7901 IC50
    6.38 μM
    Compound: 5-Fu
    Antiproliferative activity against human SGC7901 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human SGC7901 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 31202992]
    SGC-7901 IC50
    6.46 μM
    Compound: 5-FU
    Antiproliferative activity against human SGC7901 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human SGC7901 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 30921757]
    SGC-7901 IC50
    6.56 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay
    Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay
    [PMID: 25554922]
    SGC-7901 IC50
    6.8 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell viability measured for 24 hrs
    Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell viability measured for 24 hrs
    [PMID: 31945642]
    SGC-7901 IC50
    69.81 μM
    Compound: 5-Fu
    Cytotoxicity against human SGC-7901 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    Cytotoxicity against human SGC-7901 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay
    [PMID: 34628244]
    SGC-7901 EC50
    7.03 μM
    Compound: 5-FU
    Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay
    Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay
    [PMID: 26883149]
    SGC-7901 IC50
    7.11 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay
    Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay
    [PMID: 22405648]
    SGC-7901 IC50
    7.36 μg/mL
    Compound: 5-Fluorouracil
    Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay
    Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay
    [PMID: 20947362]
    SGC-7901 IC50
    7.37 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay
    Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay
    [PMID: 24119869]
    SGC-7901 IC50
    7.38 μg/mL
    Compound: 5-Fluorouracil
    Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay
    Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay
    [PMID: 20800480]
    SGC-7901 IC50
    7.38 μg/mL
    Compound: 5-Fluorouracil
    Cytotoxicity against human SGC7901 after 48 hrs by MTT assay
    Cytotoxicity against human SGC7901 after 48 hrs by MTT assay
    [PMID: 20538457]
    SGC-7901 IC50
    76 μM
    Compound: 5-FU
    Cytotoxicity against human SGC7901 cells after 2 days by alamar blue assay
    Cytotoxicity against human SGC7901 cells after 2 days by alamar blue assay
    [PMID: 22093761]
    SGC-7901 IC50
    8.7 μg/mL
    Compound: 5-FU
    Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay
    Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay
    [PMID: 22647218]
    SH-SY5Y IC50
    0.97 μM
    Compound: 5-Fu
    Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay
    Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay
    [PMID: 23685571]
    SH-SY5Y IC50
    1.09 μM
    Compound: 5-Fu
    Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay
    Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay
    [PMID: 22687745]
    SH-SY5Y GI50
    1.5 μM
    Compound: 5-FU
    Antiproliferative activity against human SH-SY5Y cells after 72 hrs by MTT-based Mosmann assay relative to control
    Antiproliferative activity against human SH-SY5Y cells after 72 hrs by MTT-based Mosmann assay relative to control
    [PMID: 26539626]
    SH-SY5Y GI50
    11.9 μM
    Compound: 5-FU
    Antiproliferative activity against human SH-SY5Y cells after 48 hrs by MTT assay
    Antiproliferative activity against human SH-SY5Y cells after 48 hrs by MTT assay
    [PMID: 29040954]
    SH-SY5Y GI50
    12 μM
    Compound: 5-Fu
    Antiproliferative activity against human SH-SY5Y cells after 48 hrs by MTT assay
    Antiproliferative activity against human SH-SY5Y cells after 48 hrs by MTT assay
    [PMID: 28763647]
    SH-SY5Y IC50
    3.26 μM
    Compound: 5-Fu
    Antiproliferative activity against human SH-SY5Y cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Antiproliferative activity against human SH-SY5Y cells assessed as cell growth inhibition after 72 hrs by MTT assay
    [PMID: 27105028]
    SiHa IC50
    218 μM
    Compound: 5-Fu
    Cytotoxicity against human SiHa cells after 48 hrs by MTT assay
    Cytotoxicity against human SiHa cells after 48 hrs by MTT assay
    [PMID: 22244588]
    SiHa GI50
    6.3 μM
    Compound: 5FU
    Growth inhibition of human SiHa cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human SiHa cells after 48 hrs by sulforhodamine B assay
    [PMID: 21489802]
    SK-BR-3 IC50
    > 100 μM
    Compound: 5-fluorouracil
    Cytotoxicity in human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity in human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay
    [PMID: 21250700]
    SK-BR-3 IC50
    > 20 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity against human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay
    [PMID: 21381696]
    SK-BR-3 GI50
    3 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against estrogen receptor deficient human SKBR3 cells after 48 hrs by SRB assay
    Antiproliferative activity against estrogen receptor deficient human SKBR3 cells after 48 hrs by SRB assay
    [PMID: 20438092]
    SK-BR-3 IC50
    38.25 μM
    Compound: 5-FU
    Antiproliferative activity against human SKBR3 cells after 72 hrs by MTT assay
    Antiproliferative activity against human SKBR3 cells after 72 hrs by MTT assay
    [PMID: 21524829]
    SK-BR-3 IC50
    38.88 μM
    Compound: 5-FU
    Cytotoxicity against human SKBR3 cells overexpressing HER2 assessed as cell growth inhibition after 48 hrs by WST-1 assay
    Cytotoxicity against human SKBR3 cells overexpressing HER2 assessed as cell growth inhibition after 48 hrs by WST-1 assay
    [PMID: 25466196]
    SK-HEP1 IC50
    12.5 μM
    Compound: 5-FU
    Anticancer activity against human SK-HEP1 cells assessed as inhibition of cell proliferation by MTT assay
    Anticancer activity against human SK-HEP1 cells assessed as inhibition of cell proliferation by MTT assay
    [PMID: 36439975]
    SK-HEP1 IC50
    4.95 μM
    Compound: 5-Fu
    Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay
    Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay
    [PMID: 35797896]
    SK-HEP1 GI50
    6.3 μM
    Compound: 5-Fu
    Growth inhibition of human SKHEP1 cells after 48 hrs by SRB assay
    Growth inhibition of human SKHEP1 cells after 48 hrs by SRB assay
    [PMID: 22512908]
    SK-HEP1 GI50
    7.6 nM
    Compound: 5FU
    Growth inhibition of human SKHEP1 cells after 48 hrs by SRB assay
    Growth inhibition of human SKHEP1 cells after 48 hrs by SRB assay
    [PMID: 23094992]
    SK-MEL IC50
    6.3 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human SK-MEL cells after 2 to 7 days by neutral red assay
    Cytotoxicity against human SK-MEL cells after 2 to 7 days by neutral red assay
    [PMID: 11374943]
    SK-MEL-2 GI50
    56.7 μM
    Compound: 5-FU
    Anticancer activity against human SK-MEL-2 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human SK-MEL-2 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    SK-MEL-2 GI50
    56.7 μM
    Compound: 5-FU
    Growth inhibition of human SK-MEL-2 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human SK-MEL-2 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    SK-MEL-2 IC50
    6.52 μM
    Compound: 5-Fu
    Antiproliferative activity against human SK-MEL-2 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay
    Antiproliferative activity against human SK-MEL-2 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay
    [PMID: 35797896]
    SK-MEL-28 GI50
    1.03 μM
    Compound: 5-FU
    Anticancer activity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    SK-MEL-28 GI50
    1.03 μM
    Compound: 5-FU
    Growth inhibition of human SK-MEL-28 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human SK-MEL-28 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    SK-MEL-28 IC50
    11 μg/mL
    Compound: 5-FU
    The compound was evaluated for antitumoral activity against human melanoma cell line P36 after 72 hr of incubation
    The compound was evaluated for antitumoral activity against human melanoma cell line P36 after 72 hr of incubation
    10.1016/S0960-894X(01)80742-3
    SK-MEL-28 IC50
    14.64 μM
    Compound: 5-FU
    Cytotoxicity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
    Cytotoxicity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay
    [PMID: 35635947]
    SK-MEL-5 GI50
    0.46 μM
    Compound: 5-FU
    Anticancer activity against human SK-MEL-5 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human SK-MEL-5 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    SK-MEL-5 GI50
    0.46 μM
    Compound: 5-FU
    Growth inhibition of human SK-MEL-5 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human SK-MEL-5 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    SK-MEL-5 IC50
    15.31 μM
    Compound: 5-FU
    Cytotoxicity against human SK-MEL-5 cells assessed as inhibition of cell viability incubated for 72 hrs under hypoxia condition by MTT assay
    Cytotoxicity against human SK-MEL-5 cells assessed as inhibition of cell viability incubated for 72 hrs under hypoxia condition by MTT assay
    [PMID: 35182815]
    SK-N-SH IC50
    10.32 μM
    Compound: 5-Fu
    Antiproliferative activity against human SK-N-SH cells after 72 hrs by MTT assay
    Antiproliferative activity against human SK-N-SH cells after 72 hrs by MTT assay
    10.1039/C6MD00169F
    SK-N-SH IC50
    7.22 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human SK-N-SH cells by MTT assay
    Antiproliferative activity against human SK-N-SH cells by MTT assay
    [PMID: 31546197]
    SK-N-SH IC50
    9.84 μM
    Compound: 5-FU
    Cytotoxicity against human SK-N-SH cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human SK-N-SH cells assessed as cell growth inhibition after 72 hrs by MTT assay
    [PMID: 27423479]
    SK-OV-3 IC50
    > 10 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human SKOV3 cells after 2 to 7 days by neutral red assay
    Cytotoxicity against human SKOV3 cells after 2 to 7 days by neutral red assay
    [PMID: 11374943]
    SK-OV-3 IC50
    20.8 μM
    Compound: 5-Fu
    Cytotoxicity against human SKOV3 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human SKOV3 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 28759877]
    SK-OV-3 IC50
    21.6 μM
    Compound: 5-Fu
    Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
    Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
    [PMID: 35092899]
    SK-OV-3 GI50
    21.8 μM
    Compound: 5-FU
    Anticancer activity against human SK-OV-3 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human SK-OV-3 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    SK-OV-3 GI50
    21.8 μM
    Compound: 5-FU
    Growth inhibition of human SKOV3 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human SKOV3 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    SK-OV-3 IC50
    22.43 μM
    Compound: 5-FU
    Cytotoxic activity against human SKOV3 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
    Cytotoxic activity against human SKOV3 cells assessed as inhibition of cell growth after 48 hrs by MTT assay
    [PMID: 26706349]
    SK-OV-3 IC50
    23.11 μM
    Compound: 5-Fu
    Cytotoxic activity against human SKOV3 cells assessed as reduction in cell viability after 72 hrs by SRB assay
    Cytotoxic activity against human SKOV3 cells assessed as reduction in cell viability after 72 hrs by SRB assay
    [PMID: 28011223]
    SK-OV-3 IC50
    24.43 μM
    Compound: 5-FU
    Cytotoxicity against human SKOV3 cells after 3 days by MTT assay
    Cytotoxicity against human SKOV3 cells after 3 days by MTT assay
    [PMID: 24095745]
    SK-OV-3 IC50
    24.43 μM
    Compound: 5-FU
    Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay
    Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay
    [PMID: 24565905]
    SK-OV-3 IC50
    24.43 μM
    Compound: 5-FU
    Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay
    Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay
    [PMID: 23988357]
    SK-OV-3 IC50
    26.34 μM
    Compound: 5-FU
    Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay
    Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay
    [PMID: 30108826]
    SK-OV-3 IC50
    26.34 μM
    Compound: 5-FU
    Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay
    Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay
    [PMID: 30092368]
    SK-OV-3 IC50
    26.34 μM
    Compound: 5-FU
    Antiproliferative activity against human SK-OV-3 cells by MTT assay
    Antiproliferative activity against human SK-OV-3 cells by MTT assay
    [PMID: 33109400]
    SK-OV-3 IC50
    27.34 μM
    Compound: 5-Fu
    Cytotoxicity against human SKOV3 cells after 2 days by MTT assay
    Cytotoxicity against human SKOV3 cells after 2 days by MTT assay
    [PMID: 25841196]
    SK-OV-3 IC50
    32.5 μM
    Compound: 5-FU
    Antiproliferative activity against human SKOV3 cells after 48 hrs by MTT assay
    Antiproliferative activity against human SKOV3 cells after 48 hrs by MTT assay
    [PMID: 28756264]
    SK-OV-3 IC50
    47.2 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human SK-OV-3 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay
    Cytotoxicity against human SK-OV-3 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay
    [PMID: 36970146]
    SMMC-7721 IC50
    > 100 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay
    Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay
    [PMID: 22537362]
    SMMC-7721 IC50
    12.47 μM
    Compound: 5-Fu
    Antiproliferative activity against human SMMC7721 cells after 24 hrs by CCK-8 assay
    Antiproliferative activity against human SMMC7721 cells after 24 hrs by CCK-8 assay
    [PMID: 29499490]
    SMMC-7721 IC50
    13.7 μM
    Compound: 5-Fu
    Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay
    Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay
    [PMID: 29475156]
    SMMC-7721 IC50
    14.2 μM
    Compound: 5-Fu
    Cytotoxicity against human SMMC7721 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human SMMC7721 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    10.1039/C5MD00240K
    SMMC-7721 IC50
    14.55 μM
    Compound: 5-Fu
    Cytotoxicity against human SMMC7721 cells after 48 hrs by CCK-8 assay
    Cytotoxicity against human SMMC7721 cells after 48 hrs by CCK-8 assay
    [PMID: 24013415]
    SMMC-7721 IC50
    15.32 μM
    Compound: 5-FU
    Antiproliferative activity against human SMMC-7721 cells by MTT assay
    Antiproliferative activity against human SMMC-7721 cells by MTT assay
    [PMID: 33109400]
    SMMC-7721 IC50
    19.25 μg/mL
    Compound: 5-fluorouracil
    Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay
    Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay
    [PMID: 28988624]
    SMMC-7721 IC50
    2.3 x 10-2 μg/mL
    Compound: fluorouracil
    Cytotoxicity against human SMMC7721 cells by MTT assay
    Cytotoxicity against human SMMC7721 cells by MTT assay
    [PMID: 22011319]
    SMMC-7721 IC50
    2.5 μM
    Compound: Fluorouracil
    Cytotoxicity against human SMMC7721 cells assessed as reduction in cell viability by MTT assay
    Cytotoxicity against human SMMC7721 cells assessed as reduction in cell viability by MTT assay
    [PMID: 31013087]
    SMMC-7721 IC50
    20 μM
    Compound: 5-FU
    Antiproliferative activity against human SMMC-7721 cells measured after 48 hrs
    Antiproliferative activity against human SMMC-7721 cells measured after 48 hrs
    [PMID: 34128674]
    SMMC-7721 IC50
    20.4 μM
    Compound: 5-Fu
    Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay
    Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay
    [PMID: 25707012]
    SMMC-7721 IC50
    26.71 μM
    Compound: 5-Fu
    Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay
    Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay
    [PMID: 23644193]
    SMMC-7721 IC50
    37.8 μM
    Compound: 5-FU
    Antiproliferative activity against human SMMC-7721 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human SMMC-7721 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    [PMID: 30739827]
    SMMC-7721 IC50
    37.8 μM
    Compound: 5-FU
    Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay
    Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay
    [PMID: 29232583]
    SMMC-7721 IC50
    4.87 μM
    Compound: 5-Fluorouracil
    Anticancer activity against human SMMC7721 cells assessed as cell survival after 48 hrs by MTT assay
    Anticancer activity against human SMMC7721 cells assessed as cell survival after 48 hrs by MTT assay
    [PMID: 25812966]
    SMMC-7721 IC50
    5.62 μM
    Compound: 5-FU
    Antiproliferative activity against human SMMC7721 cells after 48 hrs by CCK-8 assay
    Antiproliferative activity against human SMMC7721 cells after 48 hrs by CCK-8 assay
    [PMID: 27542307]
    SMMC-7721 IC50
    5.62 μM
    Compound: 5-Fu
    Antiproliferative activity against human SMMC7721 cells after 48 hrs by CCK8 assay
    Antiproliferative activity against human SMMC7721 cells after 48 hrs by CCK8 assay
    [PMID: 26786698]
    SMMC-7721 IC50
    5.62 μM
    Compound: 5-FU
    Antiproliferative activity against human SMMC7721 cells assessed as inhibition of cell proliferation by CCK8 assay
    Antiproliferative activity against human SMMC7721 cells assessed as inhibition of cell proliferation by CCK8 assay
    [PMID: 25442303]
    SMMC-7721 IC50
    51 μM
    Compound: 5-FU
    Cytotoxicity against SMMC7721 cells after 48 hrs by MTT assay
    Cytotoxicity against SMMC7721 cells after 48 hrs by MTT assay
    [PMID: 17604394]
    SMMC-7721 IC50
    67.7 μM
    Compound: 5-FU
    Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay
    Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay
    [PMID: 25164762]
    SMMC-7721 IC50
    9.78 μM
    Compound: 5-Fu
    Cytotoxicity against human SMMC7721 cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human SMMC7721 cells assessed as growth inhibition after 72 hrs by MTT assay
    [PMID: 24077182]
    SMMC-7721 IC50
    9.78 μM
    Compound: 5-Fu
    Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay
    Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay
    [PMID: 23792764]
    SN12C GI50
    0.49 μM
    Compound: 5-FU
    Anticancer activity against human SN12C cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human SN12C cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    SN12C GI50
    0.49 μM
    Compound: 5-FU
    Growth inhibition of human SN12C cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human SN12C cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    SN12C IC50
    6.5 μg/mL
    Compound: 5-Fu
    Cytotoxicity against human SN12C cells assessed as decrease in cell viability after 96 hrs
    Cytotoxicity against human SN12C cells assessed as decrease in cell viability after 96 hrs
    [PMID: 29673982]
    SNB-19 GI50
    3.81 μM
    Compound: 5-FU
    Anticancer activity against human SNB-19 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human SNB-19 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    SNB-19 GI50
    3.81 μM
    Compound: 5-FU
    Growth inhibition of human SNB19 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human SNB19 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    SNB-75 GI50
    78.7 μM
    Compound: 5-FU
    Anticancer activity against human SNB-75 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human SNB-75 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    SNB-75 GI50
    78.7 μM
    Compound: 5-FU
    Growth inhibition of human SNB75 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human SNB75 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    SNU-16 EC50
    6.4 μM
    Compound: 5FU
    Cytotoxicity against human SNU-16 cells assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay
    Cytotoxicity against human SNU-16 cells assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay
    [PMID: 35939803]
    SR GI50
    0.02 μM
    Compound: 5-FU
    Growth inhibition of human SR cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human SR cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    SR GI50
    0.0238 μM
    Compound: 5-FU
    Cytotoxicity against human SR cells after 48 hrs by SRB assay
    Cytotoxicity against human SR cells after 48 hrs by SRB assay
    [PMID: 22305543]
    SR IC50
    60.3 μM
    Compound: 5-Fluorouracil
    Antileukemic activity against human SR cells assessed as inhibition of tumor growth after 24 hrs
    Antileukemic activity against human SR cells assessed as inhibition of tumor growth after 24 hrs
    [PMID: 24657568]
    SW 1116 IC50
    18.52 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human SW1116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human SW1116 cells after 48 hrs by MTT assay
    [PMID: 28363444]
    SW 1116 IC50
    2.41 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human SW1116 cells after 48 hrs by MTT method
    Antiproliferative activity against human SW1116 cells after 48 hrs by MTT method
    [PMID: 23018096]
    SW 1116 EC50
    28.52 μg/mL
    Compound: 5-Fluorouracil
    Antiproliferative activity against human SW1116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human SW1116 cells after 48 hrs by MTT assay
    [PMID: 21889345]
    SW 1116 IC50
    37 μM
    Compound: 5-fluorouracil
    Cytotoxicity against SW1116 cells by MTT colometric method
    Cytotoxicity against SW1116 cells by MTT colometric method
    [PMID: 17253861]
    SW 1116 IC50
    5.26 μM
    Compound: 5-FU
    Cytotoxicity against human SW1116 cells after 48 hrs by MTT assay
    Cytotoxicity against human SW1116 cells after 48 hrs by MTT assay
    [PMID: 24286761]
    SW 1116 IC50
    76.92 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human SW1116 cells by disk diffusion soft agar colony formation assay
    Cytotoxicity against human SW1116 cells by disk diffusion soft agar colony formation assay
    [PMID: 31117520]
    SW 1116 IC50
    95.17 μM
    Compound: 5-FU
    Antiproliferative activity against human SW1116 cells after 48 hrs by MTT assay
    Antiproliferative activity against human SW1116 cells after 48 hrs by MTT assay
    [PMID: 21962523]
    SW1573 GI50
    4.1 μM
    Compound: 5-FU
    Growth inhibition of human SW1573 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human SW1573 cells after 48 hrs by sulforhodamine B assay
    [PMID: 19664930]
    SW1573 IC50
    4.3 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human SW1573 cells by MTT assay
    Antiproliferative activity against human SW1573 cells by MTT assay
    [PMID: 31546197]
    SW1573 GI50
    4.3 μM
    Compound: 5-FU
    Antiproliferative activity against human SW1573 cells assessed as growth inhibition after 48 hrs by SRB assay
    Antiproliferative activity against human SW1573 cells assessed as growth inhibition after 48 hrs by SRB assay
    [PMID: 31376562]
    SW1573 GI50
    4.3 μM
    Compound: 5-FU
    Antiproliferative activity against human SW1573 cells after 48 hrs by SRB assay
    Antiproliferative activity against human SW1573 cells after 48 hrs by SRB assay
    [PMID: 28728108]
    SW1573 GI50
    4.3 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human SW1573 cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human SW1573 cells after 48 hrs by sulforhodamine B assay
    [PMID: 25752525]
    SW1990 IC50
    126.4 μM
    Compound: 5-Fu
    Cytotoxicity against human SW1990 cells after 48 hrs by MTT assay
    Cytotoxicity against human SW1990 cells after 48 hrs by MTT assay
    [PMID: 26714048]
    SW1990 IC50
    45 μM
    Compound: 5-fu
    Cytotoxicity against human SW1990 cells after 48 hrs by MTT assay
    Cytotoxicity against human SW1990 cells after 48 hrs by MTT assay
    [PMID: 22304344]
    SW48 IC50
    4.4 μM
    Compound: 5-FU
    Antiproliferative activity against human SW48 cells after 72 hrs by MTT assay
    Antiproliferative activity against human SW48 cells after 72 hrs by MTT assay
    [PMID: 19743863]
    SW48 IC50
    5.3 μM
    Compound: 5-FU
    Antiproliferative activity against human SW48 cells after 72 hrs
    Antiproliferative activity against human SW48 cells after 72 hrs
    [PMID: 17548198]
    SW480 IC50
    > 30 μM
    Compound: 5-FU
    Antitumor activity against human SW480 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    Antitumor activity against human SW480 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
    [PMID: 35777102]
    SW480 IC50
    12.4 μM
    Compound: 5-Fu
    Cytotoxicity against human SW480 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    Cytotoxicity against human SW480 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    [PMID: 32987314]
    SW480 IC50
    13.1 μM
    Compound: 5-Fu
    Cytotoxicity against human SW480 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    Cytotoxicity against human SW480 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
    [PMID: 32987314]
    SW480 IC50
    13.16 μM
    Compound: 5-FU
    Cytotoxicity against human SW480 cells by MTT assay
    Cytotoxicity against human SW480 cells by MTT assay
    [PMID: 18644718]
    SW480 IC50
    15.3 μM
    Compound: 5-Fu
    Cytotoxicity against human SW480 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
    Cytotoxicity against human SW480 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
    [PMID: 32987314]
    SW480 IC50
    15.71 μM
    Compound: 5-Fu
    Cytotoxicity against human SW480 cells after 24 hrs by MTT assay
    Cytotoxicity against human SW480 cells after 24 hrs by MTT assay
    [PMID: 22182926]
    SW480 IC50
    15.71 μM
    Compound: 5-Fu
    Cytotoxicity against human SW480 cells after 48 hrs by MTT assay
    Cytotoxicity against human SW480 cells after 48 hrs by MTT assay
    [PMID: 23920246]
    SW480 IC50
    15.71 μM
    Compound: 5-Fu
    Cytotoxicity against human SW480 cells by after 48 hrs by MTT assay
    Cytotoxicity against human SW480 cells by after 48 hrs by MTT assay
    [PMID: 22579780]
    SW480 IC50
    158.2 μM
    Compound: 5-Fu
    Cytotoxicity against human SW480 cells after 48 hrs by MTT assay
    Cytotoxicity against human SW480 cells after 48 hrs by MTT assay
    [PMID: 23356786]
    SW480 IC50
    2.1 μM
    Compound: 5-FU
    Antiproliferative activity against human SW480 cells after 72 hrs by MTT assay
    Antiproliferative activity against human SW480 cells after 72 hrs by MTT assay
    [PMID: 19743863]
    SW480 IC50
    21.93 μM
    Compound: 5-FU
    Anticancer activity against human SW480 cells assessed as inhibition of cell proliferation by MTT assay
    Anticancer activity against human SW480 cells assessed as inhibition of cell proliferation by MTT assay
    [PMID: 36439975]
    SW480 IC50
    26.26 μM
    Compound: 5-FU
    Antiproliferative activity against p53 deficient human SW480 cells after 72 hrs by proliferative assay
    Antiproliferative activity against p53 deficient human SW480 cells after 72 hrs by proliferative assay
    [PMID: 18469809]
    SW480 ED50
    3.09 μg/mL
    Compound: 5-fluorouracil
    Cytotoxicity against human SW480 cells after 3 days by trypan blue exclusion technique
    Cytotoxicity against human SW480 cells after 3 days by trypan blue exclusion technique
    [PMID: 1800632]
    SW480 IC50
    3.5 μM
    Compound: 5-FU
    Antiproliferative activity against human SW480 cells after 72 hrs
    Antiproliferative activity against human SW480 cells after 72 hrs
    [PMID: 17548198]
    SW480 IC50
    3.69 μM
    Compound: 5-Fu
    Cytotoxicity against human SW480 cells after 3 days by SRB assay
    Cytotoxicity against human SW480 cells after 3 days by SRB assay
    [PMID: 24704691]
    SW480 IC50
    32.72 μM
    Compound: 5-Fu
    Antiproliferative activity against human SW480 cells after 48 hrs by MTT assay
    Antiproliferative activity against human SW480 cells after 48 hrs by MTT assay
    10.1039/C5MD00163C
    SW480 IC50
    57 μM
    Compound: 5-FU
    Antiproliferative activity against human p53 deficient SW480 cells after 72 hrs by celltiter-glo assay
    Antiproliferative activity against human p53 deficient SW480 cells after 72 hrs by celltiter-glo assay
    [PMID: 20873740]
    SW480 IC50
    6 μg/mL
    Compound: 5-FU
    The compound was evaluated for antitumoral activity against human cancer cell line SW480 after 72 hr of incubation
    The compound was evaluated for antitumoral activity against human cancer cell line SW480 after 72 hr of incubation
    10.1016/S0960-894X(01)80742-3
    SW480 IC50
    8.1 μM
    Compound: 5-Fu
    Cytotoxicity against human SW480 cells after 72 hrs by MTT assay
    Cytotoxicity against human SW480 cells after 72 hrs by MTT assay
    [PMID: 23792763]
    SW480 IC50
    8.1 μM
    Compound: 5-FU
    Antiproliferative activity against human SW480 cells after 72 hrs by MTT method
    Antiproliferative activity against human SW480 cells after 72 hrs by MTT method
    [PMID: 17524655]
    SW480 IC50
    9.7 μM
    Compound: 5-FU
    Antiproliferative activity against human SW480 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Antiproliferative activity against human SW480 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 33538581]
    SW-620 IC50
    > 10 μM
    Compound: 5-FU
    Antiproliferative activity against human SW620 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human SW620 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 32127259]
    SW-620 CC50
    > 2512 μM
    Compound: 5-Fu
    Cytotoxicity against human SW620 cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human SW620 cells after 48 hrs by sulforhodamine B assay
    [PMID: 26727215]
    SW-620 EC50
    > 50 μM
    Compound: 5-FU
    Antiproliferative activity against human SW620 cells after 24 hrs by MTT assay
    Antiproliferative activity against human SW620 cells after 24 hrs by MTT assay
    [PMID: 25198997]
    SW-620 IC50
    0.08 μM
    Compound: 5-FU
    Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assay
    [PMID: 31734024]
    SW-620 IC50
    0.08 μM
    Compound: 5-FU
    Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay
    Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay
    [PMID: 29133046]
    SW-620 IC50
    0.08 μM
    Compound: 5-FU
    Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay
    Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay
    [PMID: 28525845]
    SW-620 IC50
    0.08 μM
    Compound: 5-FU
    Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay
    Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay
    [PMID: 27875779]
    SW-620 IC50
    0.79 μM
    Compound: 5-FU
    Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay
    Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay
    [PMID: 26617970]
    SW-620 IC50
    0.79 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assay
    Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assay
    [PMID: 26291038]
    SW-620 GI50
    0.92 μM
    Compound: 5-FU
    Anticancer activity against human SW-620 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human SW-620 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    SW-620 GI50
    0.92 μM
    Compound: 5-FU
    Growth inhibition of human SW620 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human SW620 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    SW-620 IC50
    10 μM
    Compound: 5-FU
    Cytotoxicity against human SW620 cells after 24 hrs by MTT assay
    Cytotoxicity against human SW620 cells after 24 hrs by MTT assay
    [PMID: 32223193]
    SW-620 IC50
    13.25 μM
    Compound: 5-FU
    Antiproliferative activity against human SW620 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Antiproliferative activity against human SW620 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 36269639]
    SW-620 IC50
    14.8 μM
    Compound: 5-Fu
    Cytotoxicity against human SW620 cells after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human SW620 cells after 48 hrs by sulforhodamine B assay
    [PMID: 26727215]
    SW-620 IC50
    15.29 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human SW-620 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay
    Antiproliferative activity against human SW-620 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay
    [PMID: 32387836]
    SW-620 IC50
    18.6 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human SW620 cells assessed as inhibition of tumor growth after 24 hrs
    Cytotoxicity against human SW620 cells assessed as inhibition of tumor growth after 24 hrs
    [PMID: 24657568]
    SW-620 IC50
    3.38 μM
    Compound: 5-FU
    Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay
    Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay
    [PMID: 21524829]
    SW-620 IC50
    5.3 μM
    Compound: 5-FU
    Cytotoxicity against human SW620 cells after 72 hrs by MTS assay
    Cytotoxicity against human SW620 cells after 72 hrs by MTS assay
    [PMID: 25066282]
    SW-620 IC50
    6.68 μM
    Compound: 5-Fluoruracil
    Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay
    Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay
    [PMID: 22555152]
    SW-620 IC50
    6.96 μM
    Compound: 5-FU
    Cytotoxicity against human SW-620 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Cytotoxicity against human SW-620 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 32203786]
    SW-620 IC50
    8.7 μM
    Compound: 5-FU
    Antiproliferative activity against human SW620 cells after 3 days by MTT assay
    Antiproliferative activity against human SW620 cells after 3 days by MTT assay
    [PMID: 18424155]
    SW-620 IC50
    9 μM
    Compound: 5-FU
    Antitumor activity against human SW620 cells after 24 hrs by MTT assay
    Antitumor activity against human SW620 cells after 24 hrs by MTT assay
    [PMID: 20211564]
    SW-620 IC50
    9 μM
    Compound: 5-FU
    Growth inhibition of human SW620 cells after 72 hrs by MTT assay
    Growth inhibition of human SW620 cells after 72 hrs by MTT assay
    [PMID: 18640746]
    SW620/5-FU EC50
    > 1000 μM
    Compound: 5-FU
    Antiproliferative activity against human SW620/5-FU cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Antiproliferative activity against human SW620/5-FU cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 34688013]
    SW620/5-FU EC50
    > 1000 μM
    Compound: 5-FU
    Reversal of 5-FU resistance against human SW620/5-FU cells assessed as inhibition of cell proliferation measured after 72 hrs in presence of 5-FU by MTT assay
    Reversal of 5-FU resistance against human SW620/5-FU cells assessed as inhibition of cell proliferation measured after 72 hrs in presence of 5-FU by MTT assay
    [PMID: 34411894]
    SW780 IC50
    6.99 μM
    Compound: 5-FU
    Cytotoxicity against human SW780 cells assessed as growth inhibition after 72 hrs by CCK8 assay
    Cytotoxicity against human SW780 cells assessed as growth inhibition after 72 hrs by CCK8 assay
    [PMID: 27597411]
    T-24 IC50
    12.89 μM
    Compound: 5-FU
    Cytotoxicity against human T24 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    Cytotoxicity against human T24 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay
    [PMID: 33740546]
    T-24 IC50
    25.23 μM
    Compound: 5-FU
    Antiproliferative activity against human T24 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay
    Antiproliferative activity against human T24 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay
    [PMID: 37122546]
    T-24 IC50
    37.56 μM
    Compound: 5-FU
    Cytotoxicity against human T24 cells assessed as cell viability after 48 hrs by MTT assay
    Cytotoxicity against human T24 cells assessed as cell viability after 48 hrs by MTT assay
    [PMID: 25841199]
    T-24 IC50
    39.4 μM
    Compound: 5-Fu
    Antiproliferative activity against human T24 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
    Antiproliferative activity against human T24 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
    [PMID: 35092899]
    T-24 IC50
    40.14 μM
    Compound: 5-FU
    Cytotoxicity in human T24 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity in human T24 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 28754470]
    T-24 IC50
    40.14 μM
    Compound: 5-FU
    Antiproliferative activity against human T-24 cells by MTT assay
    Antiproliferative activity against human T-24 cells by MTT assay
    [PMID: 33109400]
    T-24 IC50
    40.57 μM
    Compound: 5-Fu
    Cytotoxicity against human T24 cells after 2 days by MTT assay
    Cytotoxicity against human T24 cells after 2 days by MTT assay
    [PMID: 25841196]
    T-24 IC50
    6 μg/mL
    Compound: 5-FU
    The compound was evaluated for antitumoral activity against human cancer cell line T24 after 72 hr of incubation
    The compound was evaluated for antitumoral activity against human cancer cell line T24 after 72 hr of incubation
    10.1016/S0960-894X(01)80742-3
    T47D IC50
    0.6 μM
    Compound: 5-FU
    Antiproliferative activity against human T47D cells after 72 hrs by MTT assay
    Antiproliferative activity against human T47D cells after 72 hrs by MTT assay
    [PMID: 19743863]
    T47D IC50
    10.56 μM
    Compound: 5-Fu
    Cytotoxicity against human T47D cells after 3 days by SRB assay
    Cytotoxicity against human T47D cells after 3 days by SRB assay
    [PMID: 24704691]
    T47D IC50
    12.1 μM
    Compound: 5-FU
    Antiproliferative activity against human T47D cells after 48 hrs by MTT assay
    Antiproliferative activity against human T47D cells after 48 hrs by MTT assay
    [PMID: 28400238]
    T47D IC50
    171.06 μM
    Compound: Fluorouracil
    Cytotoxicity against human T47D cells after 48 hrs by MTT assay
    Cytotoxicity against human T47D cells after 48 hrs by MTT assay
    [PMID: 28789892]
    T47D GI50
    29 μM
    Compound: 5-FU
    Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay
    [PMID: 19664930]
    T47D IC50
    4.3 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human T47D cells by MTT assay
    Antiproliferative activity against human T47D cells by MTT assay
    [PMID: 31546197]
    T47D GI50
    47 μM
    Compound: 5-FU
    Antiproliferative activity against human T47D cells assessed as growth inhibition after 48 hrs by SRB assay
    Antiproliferative activity against human T47D cells assessed as growth inhibition after 48 hrs by SRB assay
    [PMID: 31376562]
    T47D GI50
    47 μM
    Compound: 5-FU
    Antiproliferative activity against human T47D cells after 48 hrs by SRB assay
    Antiproliferative activity against human T47D cells after 48 hrs by SRB assay
    [PMID: 28728108]
    T47D GI50
    47 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human T47D cells expressing estrogen receptor after 48 hrs by SRB assay
    Antiproliferative activity against human T47D cells expressing estrogen receptor after 48 hrs by SRB assay
    [PMID: 20438092]
    T47D GI50
    47 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human T47D cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human T47D cells after 48 hrs by sulforhodamine B assay
    [PMID: 25752525]
    T47D ED50
    50.2 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human T47D cells after 3 hrs by Alamar Blue assay
    Cytotoxicity against human T47D cells after 3 hrs by Alamar Blue assay
    [PMID: 24020806]
    T47D IC50
    51.7 μM
    Compound: 5-FU
    Growth inhibition of human T47D cells after 24 hrs by MTT assay
    Growth inhibition of human T47D cells after 24 hrs by MTT assay
    [PMID: 28011220]
    T47D IC50
    51.8 μM
    Compound: 5-FU
    Cytotoxicity against human T47D cells after 24 hrs by MTT assay
    Cytotoxicity against human T47D cells after 24 hrs by MTT assay
    [PMID: 23202484]
    T47D IC50
    6.7 μM
    Compound: 5-FU
    Antiproliferative activity against human T47D cells assessed as reduction in cell viability incubated for 24 hrs by sulforhodamine B assay
    Antiproliferative activity against human T47D cells assessed as reduction in cell viability incubated for 24 hrs by sulforhodamine B assay
    [PMID: 34847409]
    T47D IC50
    7.9 μM
    Compound: 5-FU
    Cytotoxicity against human T47D cells after 72 hrs by SRB assay
    Cytotoxicity against human T47D cells after 72 hrs by SRB assay
    [PMID: 25462277]
    T47D GI50
    8.12 μM
    Compound: 5-FU
    Anticancer activity against human T47D cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human T47D cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    T47D GI50
    8.12 μM
    Compound: 5-FU
    Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    T47D IC50
    8.91 μM
    Compound: 5FU
    Cytotoxicity against human T47D cells incubated for 72 hrs by SRB assay
    Cytotoxicity against human T47D cells incubated for 72 hrs by SRB assay
    [PMID: 22867707]
    T84 IC50
    > 10 μM
    Compound: 5-FU
    Antiproliferative activity against human T84 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    Antiproliferative activity against human T84 cells assessed as reduction in cell viability after 72 hrs by MTT assay
    [PMID: 32127259]
    T84 IC50
    3.4 μM
    Compound: 5-Fu
    Antiproliferative activity against human T84 cells after 3 days by sulforhodamine B assay
    Antiproliferative activity against human T84 cells after 3 days by sulforhodamine B assay
    [PMID: 30248657]
    T84 IC50
    6.2 μM
    Compound: 5-FU
    Antiproliferative activity against human T84 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay
    Antiproliferative activity against human T84 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay
    [PMID: 26731300]
    TE-1 IC50
    16.53 μM
    Compound: 5-Fu
    Cytotoxicity against human TE1 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    Cytotoxicity against human TE1 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay
    [PMID: 30388465]
    TE-1 IC50
    16.53 μM
    Compound: 5-Fu
    Antiproliferative activity against human TE1 cells after 72 hrs by MTT assay
    Antiproliferative activity against human TE1 cells after 72 hrs by MTT assay
    [PMID: 29635165]
    TE-1 IC50
    17.32 μM
    Compound: 5-FU
    Cytotoxicity against human TE1 cells assessed as growth inhibition after 72 hrs by CCK8 assay
    Cytotoxicity against human TE1 cells assessed as growth inhibition after 72 hrs by CCK8 assay
    [PMID: 27597411]
    THP-1 IC50
    0.01 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human THP1 cells assessed as inhibition of cell growth after 48 hrs by sulforhodamine B assay
    Cytotoxicity against human THP1 cells assessed as inhibition of cell growth after 48 hrs by sulforhodamine B assay
    10.1039/C5MD00289C
    THP-1 IC50
    0.04 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human THP1 cells after 48 hrs by SRB assay
    Cytotoxicity against human THP1 cells after 48 hrs by SRB assay
    [PMID: 25259515]
    THP-1 IC50
    0.54 μg/mL
    Compound: 5-Fluorouracil
    Cytotoxicity against human THP1 cells after 24 hrs by MTT assay
    Cytotoxicity against human THP1 cells after 24 hrs by MTT assay
    [PMID: 23352638]
    THP-1 IC50
    1 μM
    Compound: 5-FU
    Antiproliferative activity against human THP1 cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human THP1 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23501113]
    THP-1 IC50
    1.7 μM
    Compound: 5-FU
    Cytotoxicity against human THP1 cells after 48 hrs by MTT assay
    Cytotoxicity against human THP1 cells after 48 hrs by MTT assay
    [PMID: 26854375]
    THP-1 IC50
    4.87 μM
    Compound: 5-FU
    Antiproliferative activity against human THP1 cells treated for 24 hrs measured after 72 hrs by MTT assay
    Antiproliferative activity against human THP1 cells treated for 24 hrs measured after 72 hrs by MTT assay
    [PMID: 29037951]
    TIG-3 IC50
    8.4 μM
    Compound: 5-fluorouracil
    Antiproliferative activity against human TIG3 cells after 72 hrs by WST8 assay
    Antiproliferative activity against human TIG3 cells after 72 hrs by WST8 assay
    [PMID: 25919052]
    TK-10 GI50
    1.12 μM
    Compound: 5-FU
    Anticancer activity against human TK-10 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human TK-10 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    TK-10 GI50
    1.12 μM
    Compound: 5-FU
    Growth inhibition of human TK10 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human TK10 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    U-251 IC50
    0.54 μM
    Compound: 5-fluorouracil
    Cytotoxicity against human U251 cells assessed as reduction in cell viability by SRB assay
    Cytotoxicity against human U251 cells assessed as reduction in cell viability by SRB assay
    [PMID: 30660827]
    U-251 GI50
    0.9 μM
    Compound: 5-FU
    Growth inhibition of human U251 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human U251 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    U-251 GI50
    0.92 μM
    Compound: 5-FU
    Anticancer activity against human U-251 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human U-251 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    U-251 IC50
    24.69 μM
    Compound: 5-Fu
    Cytotoxicity against human U251 cells after 48 hrs by MTT assay
    Cytotoxicity against human U251 cells after 48 hrs by MTT assay
    [PMID: 27133593]
    U-251 GI50
    30.1 μM
    Compound: 5-Fu
    Antiproliferative activity against human U251 cells incubated for 48 hrs by MTT assay
    Antiproliferative activity against human U251 cells incubated for 48 hrs by MTT assay
    [PMID: 32832031]
    U-251 IC50
    38.68 μM
    Compound: 5-Fu
    Cytotoxicity against human U251 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay
    Cytotoxicity against human U251 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay
    [PMID: 27400887]
    U-251 IC50
    48.68 μM
    Compound: 5FU
    Cytotoxicity against human U251 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay
    Cytotoxicity against human U251 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay
    [PMID: 28038327]
    U-251 GI50
    69.6 nM
    Compound: 5FU
    Growth inhibition of human U251 cells after 48 hrs by SRB assay
    Growth inhibition of human U251 cells after 48 hrs by SRB assay
    [PMID: 23094992]
    U-251 GI50
    82 μM
    Compound: 5-Fu
    Growth inhibition of human U251 cells after 48 hrs by SRB assay
    Growth inhibition of human U251 cells after 48 hrs by SRB assay
    [PMID: 22512908]
    U-266 IC50
    43.48 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human U266 cells in presence of ubenimex after 48 hrs by MTT assay
    Antiproliferative activity against human U266 cells in presence of ubenimex after 48 hrs by MTT assay
    [PMID: 29202398]
    U-266 IC50
    66.22 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human U266 cells after 48 hrs by MTT assay
    Antiproliferative activity against human U266 cells after 48 hrs by MTT assay
    [PMID: 29202398]
    U2OS IC50
    > 20 μM
    Compound: 5-FU
    Cytotoxicity against human U2OS cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    Cytotoxicity against human U2OS cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay
    [PMID: 36331508]
    U2OS IC50
    13.02 μM
    Compound: 5-Fu
    Antiproliferative activity against human U2OS cells after 72 hrs by MTT assay
    Antiproliferative activity against human U2OS cells after 72 hrs by MTT assay
    [PMID: 35609396]
    U2OS IC50
    13.18 μM
    Compound: 5-FU
    Antiproliferative activity against human U2OS cells expressing p53 gene after 72 hrs by proliferative assay
    Antiproliferative activity against human U2OS cells expressing p53 gene after 72 hrs by proliferative assay
    [PMID: 18469809]
    U2OS IC50
    16 μM
    Compound: 5-FU
    Antiproliferative activity against human U2OS cells expressing p53 after 72 hrs by celltiter-glo assay
    Antiproliferative activity against human U2OS cells expressing p53 after 72 hrs by celltiter-glo assay
    [PMID: 20873740]
    U2OS IC50
    7.2 μg/mL
    Compound: 5-FU
    Cytotoxicity against human U2OS cells after 36 hrs by MTT assay
    Cytotoxicity against human U2OS cells after 36 hrs by MTT assay
    [PMID: 20961091]
    U-87MG ATCC IC50
    > 50 μM
    Compound: 5-FU
    Antiproliferative activity against human U-87 MG cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Antiproliferative activity against human U-87 MG cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 33538581]
    U-87MG ATCC GI50
    13 μM
    Compound: 5-FU
    Neurotoxicity against human U87 cells assessed as growth inhibition measured after 48 hrs by MTT assay
    Neurotoxicity against human U87 cells assessed as growth inhibition measured after 48 hrs by MTT assay
    [PMID: 27688184]
    U-87MG ATCC IC50
    15.48 μM
    Compound: F
    Cytotoxicity against human U87MG cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human U87MG cells assessed as decrease in cell viability after 48 hrs by MTT assay
    [PMID: 27210438]
    U-87MG ATCC IC50
    18.25 μM
    Compound: 5-FU
    Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 72 hrs by Z2 coulter counter method
    Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 72 hrs by Z2 coulter counter method
    [PMID: 27081742]
    U-87MG ATCC IC50
    2.42 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human U87MG cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Antiproliferative activity against human U87MG cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 31546197]
    U-87MG ATCC IC50
    219.6 μM
    Compound: 5-FU
    Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 48 hrs by Z2 coulter counter method
    Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 48 hrs by Z2 coulter counter method
    [PMID: 27081742]
    U-87MG ATCC IC50
    22 μM
    Compound: 5-Fu
    Cytotoxicity against human U87 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    Cytotoxicity against human U87 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay
    [PMID: 30568759]
    U-87MG ATCC IC50
    3.61 μM
    Compound: 5-FU
    Cytotoxicity against human U87MG cells assessed as growth inhibition after 72 hrs by MTT assay
    Cytotoxicity against human U87MG cells assessed as growth inhibition after 72 hrs by MTT assay
    [PMID: 26735909]
    U-87MG ATCC IC50
    3.65 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human U87MG cells after 48 hrs by MTT assay
    Antiproliferative activity against human U87MG cells after 48 hrs by MTT assay
    [PMID: 27092413]
    U-87MG ATCC IC50
    38.2 μM
    Compound: 5-Fu
    Antiproliferative activity against human U87 cells assessed as cell-growth inhibition after 48 hrs by MTT assay
    Antiproliferative activity against human U87 cells assessed as cell-growth inhibition after 48 hrs by MTT assay
    [PMID: 25453794]
    U-87MG ATCC IC50
    45.3 μM
    Compound: 5-FU
    Antiproliferative activity against human U87 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    Antiproliferative activity against human U87 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
    [PMID: 30739827]
    U-87MG ATCC IC50
    49298 μM
    Compound: 5-FU
    Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 24 hrs by Z2 coulter counter method
    Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 24 hrs by Z2 coulter counter method
    [PMID: 27081742]
    U-87MG ATCC IC50
    5.61 μM
    Compound: 5-Fu
    Antiproliferative activity against human U87 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    Antiproliferative activity against human U87 cells assessed as cell growth inhibition after 72 hrs by MTT assay
    [PMID: 27105028]
    U-937 IC50
    0.87 μg/mL
    Compound: 5-Fluorouracil
    Cytotoxicity against human U937 cells after 24 hrs by MTT assay
    Cytotoxicity against human U937 cells after 24 hrs by MTT assay
    [PMID: 23352638]
    U-937 IC50
    1.07 μM
    Compound: 5-FU
    Cytotoxicity against human U937 cells after 72 hrs by MTT assay
    Cytotoxicity against human U937 cells after 72 hrs by MTT assay
    [PMID: 22959518]
    U-937 IC50
    23.93 μM
    Compound: 5-Fu
    Growth inhibition against human U937 cells after 48 hrs by MTT assay
    Growth inhibition against human U937 cells after 48 hrs by MTT assay
    [PMID: 23999046]
    U-937 IC50
    23.93 μM
    Compound: 5-Fu
    Cytotoxicity against human U937 cells after 48 hrs by MTT assay
    Cytotoxicity against human U937 cells after 48 hrs by MTT assay
    [PMID: 23558238]
    U-937 IC50
    28.76 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
    Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
    [PMID: 29202398]
    U-937 IC50
    4.7 μM
    Compound: 5-FU
    Cytotoxicity against Homo sapiens (human) U937 cells after 96 hr by MTT assay
    Cytotoxicity against Homo sapiens (human) U937 cells after 96 hr by MTT assay
    10.1007/s00044-011-9778-y
    U-937 IC50
    56.28 μM
    Compound: 5-Fu
    Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
    Antiproliferative activity against human U937 cells after 48 hrs by MTT assay
    [PMID: 29958763]
    U-937 IC50
    9.56 μM
    Compound: 2; 5-FU
    Antiproliferative activity against human U937 cells in presence of ubenimex after 48 hrs by MTT assay
    Antiproliferative activity against human U937 cells in presence of ubenimex after 48 hrs by MTT assay
    [PMID: 29202398]
    UACC-257 GI50
    3.55 μM
    Compound: 5-FU
    Anticancer activity against human UACC-257 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human UACC-257 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    UACC-257 GI50
    3.55 μM
    Compound: 5-FU
    Growth inhibition of human UACC257 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human UACC257 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    UACC-62 GI50
    0.52 μM
    Compound: 5-FU
    Anticancer activity against human UACC-62 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human UACC-62 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    UACC-62 GI50
    0.52 μM
    Compound: 5-FU
    Growth inhibition of human UACC62 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human UACC62 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    UACC-62 IC50
    264 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human UACC62 cells after 48 hrs by MTT assay
    Cytotoxicity against human UACC62 cells after 48 hrs by MTT assay
    [PMID: 24177365]
    UACC-812 IC50
    3.1 μM
    Compound: 5-FU
    Antiproliferative activity against human UACC-812 cells after 72 hrs by MTT assay
    Antiproliferative activity against human UACC-812 cells after 72 hrs by MTT assay
    [PMID: 19743863]
    UO-31 GI50
    1.42 μM
    Compound: 5-FU
    Anticancer activity against human UO-31 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    Anticancer activity against human UO-31 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay
    [PMID: 35182815]
    UO-31 GI50
    1.42 μM
    Compound: 5-FU
    Growth inhibition of human UO31 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human UO31 cells after 48 hrs by sulforhodamine B assay
    [PMID: 23887055]
    Vero IC50
    > 100 μM
    Compound: 5-Fu
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay
    [PMID: 22687745]
    Vero IC50
    0.05 mM
    Compound: 5-FU
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells assessed as inhibition of cell survival after 96 hr
    Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells assessed as inhibition of cell survival after 96 hr
    10.1007/s00044-012-0201-0
    Vero IC50
    4.5 μM
    Compound: 1, 5-FU
    Growth inhibition of african green monkey Vero cells by crystal violet assay
    Growth inhibition of african green monkey Vero cells by crystal violet assay
    [PMID: 23075414]
    Vero IC50
    6.4 μg/mL
    Compound: 5-FU
    Cytotoxicity against African green monkey Vero cells after 96 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells after 96 hrs by MTT assay
    [PMID: 23022735]
    Vero IC50
    6.5 μg/mL
    Compound: 5-Fu
    Cytotoxicity against african green monkey Vero cells after 96 hrs by MTT assay
    Cytotoxicity against african green monkey Vero cells after 96 hrs by MTT assay
    [PMID: 22204901]
    Vero IC50
    6.5 μg/mL
    Compound: 5-Fu
    Cytotoxicity against african green monkey Vero cells assessed as loss of cell monolayers after 96 hrs
    Cytotoxicity against african green monkey Vero cells assessed as loss of cell monolayers after 96 hrs
    [PMID: 21130542]
    Vero IC50
    8 μM
    Compound: 5-FU
    Antiproliferative activity against african green monkey Vero cells after 48 hrs by MTT assay
    Antiproliferative activity against african green monkey Vero cells after 48 hrs by MTT assay
    [PMID: 23800391]
    Vero IC50
    9.71 μM
    Compound: 5-Fu
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
    Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
    [PMID: 23685571]
    WI-38 IC50
    > 40 μM
    Compound: 5-Fu
    Antiproliferative activity against human WI-38 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
    Antiproliferative activity against human WI-38 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
    [PMID: 35092899]
    WI-38 IC50
    0.02 mM
    Compound: 5-FU
    Cytotoxicity against Homo sapiens (human) WI38 cells assessed as inhibition of cell survival after 96 hr
    Cytotoxicity against Homo sapiens (human) WI38 cells assessed as inhibition of cell survival after 96 hr
    10.1007/s00044-012-0201-0
    WI-38 IC50
    0.051 mM
    Compound: 5-Fluorouracil
    Cytotoxicity in human WI38 cells assessed as reduction in cell viability by MTT assay
    Cytotoxicity in human WI38 cells assessed as reduction in cell viability by MTT assay
    [PMID: 28334654]
    WI-38 IC50
    0.94 μM
    Compound: 5-FU
    Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay
    Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay
    [PMID: 29133046]
    WI-38 IC50
    0.94 μM
    Compound: 5-FU
    Cytotoxicity against human WI38 cells after 72 hrs by MTT assay
    Cytotoxicity against human WI38 cells after 72 hrs by MTT assay
    [PMID: 28525845]
    WI-38 IC50
    0.94 μM
    Compound: 5-FU
    Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay
    Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay
    [PMID: 27875779]
    WI-38 IC50
    10 μM
    Compound: 5-FU
    Cytotoxicity against human WI38 cells after 3 days by MTT assay
    Cytotoxicity against human WI38 cells after 3 days by MTT assay
    [PMID: 18424155]
    WI-38 IC50
    10 μM
    Compound: 5-FU
    Antiproliferative activity against human WI38 cells after 48 hrs by MTT assay
    Antiproliferative activity against human WI38 cells after 48 hrs by MTT assay
    [PMID: 23800391]
    WI-38 IC50
    18.5 μM
    Compound: 5-FU
    Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay
    Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay
    [PMID: 21524829]
    WI-38 IC50
    201.9 μM
    Compound: 5-FU
    Cytotoxicity in human W138 cells assessed as growth inhibition incubated for 24 hrs by MTT assay
    Cytotoxicity in human W138 cells assessed as growth inhibition incubated for 24 hrs by MTT assay
    [PMID: 31128448]
    WI-38 IC50
    24.66 μM
    Compound: 5-Fluoruracil
    Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay
    Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay
    [PMID: 22555152]
    WI-38 IC50
    3.2 μg/mL
    Compound: 5-Fu
    Cytotoxicity against human WI38 cells after 96 hrs by MTT assay
    Cytotoxicity against human WI38 cells after 96 hrs by MTT assay
    [PMID: 22204901]
    WI-38 IC50
    3.2 μg/mL
    Compound: 5-Fu
    Cytotoxicity against human WI38 cells assessed as loss of cell monolayers after 96 hrs
    Cytotoxicity against human WI38 cells assessed as loss of cell monolayers after 96 hrs
    [PMID: 21130542]
    WI-38 IC50
    38.91 μM
    Compound: 5-FU
    Cytotoxicity against human WI38 cells assessed as growth inhibition after 48 hrs by MTT assay
    Cytotoxicity against human WI38 cells assessed as growth inhibition after 48 hrs by MTT assay
    [PMID: 26873416]
    WI-38 IC50
    4 μg/mL
    Compound: 5-FU
    Cytotoxicity against human WI38 cells after 96 hrs by MTT assay
    Cytotoxicity against human WI38 cells after 96 hrs by MTT assay
    [PMID: 23022735]
    WI-38 IC50
    4 μM
    Compound: 5-FU
    Cytotoxicity against human WI38 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human WI38 cells assessed as reduction in cell viability after 48 hrs by MTT assay
    [PMID: 27343853]
    WI-38 IC50
    4.1 μM
    Compound: 5-Fu
    Cytotoxicity against human WI38 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity against human WI38 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
    [PMID: 31276896]
    WI-38 IC50
    5.7 μM
    Compound: 5-Fluorouracil
    Cytotoxicity in human WI38 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay
    Cytotoxicity in human WI38 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay
    [PMID: 28926764]
    WI-38 IC50
    5.73 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human W138 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    Cytotoxicity against human W138 cells assessed as decrease in cell viability after 48 hrs by MTT assay
    [PMID: 28623814]
    WI-38 IC50
    6.8 μM
    Compound: 5-FU
    Cytotoxicity against human WI38 cells assessed as decrease in cell viability after 72 hrs by WST8 assay
    Cytotoxicity against human WI38 cells assessed as decrease in cell viability after 72 hrs by WST8 assay
    [PMID: 28558970]
    WI-38 IC50
    62 μM
    Compound: 5-Fluorouracil
    Cytotoxicity against human WI-38 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay
    Cytotoxicity against human WI-38 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay
    [PMID: 36970146]
    WI-38 IC50
    78.5 μM
    Compound: 5-FU
    Cytotoxicity against human WI-38 cells assessed as reduction in cell viability after 72 hrs by SRB assay
    Cytotoxicity against human WI-38 cells assessed as reduction in cell viability after 72 hrs by SRB assay
    [PMID: 32485532]
    WI-38 IC50
    8.4 μM
    Compound: 5-FU
    Cytotoxicity activity against human WI38 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    Cytotoxicity activity against human WI38 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay
    [PMID: 30856408]
    WI-38 IC50
    9.3 μM
    Compound: 5-FU
    Cytotoxicity against human WI38 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human WI38 cells assessed as reduction in cell viability after 24 hrs by MTT assay
    [PMID: 27951487]
    WiDr IC50
    10.5 μM
    Compound: 5-FU
    Anticancer activity against human WiDr cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    Anticancer activity against human WiDr cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay
    [PMID: 34425478]
    WiDr IC50
    4.3 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human WiDr cells by MTT assay
    Antiproliferative activity against human WiDr cells by MTT assay
    [PMID: 31546197]
    WiDr GI50
    49 μM
    Compound: 5-FU
    Antiproliferative activity against human WiDr cells assessed as growth inhibition after 48 hrs by SRB assay
    Antiproliferative activity against human WiDr cells assessed as growth inhibition after 48 hrs by SRB assay
    [PMID: 31376562]
    WiDr GI50
    49 μM
    Compound: 5-FU
    Antiproliferative activity against human WiDr cells after 48 hrs by SRB assay
    Antiproliferative activity against human WiDr cells after 48 hrs by SRB assay
    [PMID: 28728108]
    WiDr GI50
    49 μM
    Compound: 5-Fluorouracil
    Antiproliferative activity against human WiDr cells after 48 hrs by sulforhodamine B assay
    Antiproliferative activity against human WiDr cells after 48 hrs by sulforhodamine B assay
    [PMID: 25752525]
    WiDr GI50
    50 μM
    Compound: 5-FU
    Growth inhibition of human WiDr cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human WiDr cells after 48 hrs by sulforhodamine B assay
    [PMID: 19664930]
    WISH IC50
    7.1 μM
    Compound: 5-FU
    Cytotoxicity against human WISH cells assessed as reduction in cell viability after 24 hrs by MTT assay
    Cytotoxicity against human WISH cells assessed as reduction in cell viability after 24 hrs by MTT assay
    [PMID: 27951487]
    WM 266-4 GI50
    28.76 μM
    Compound: 5-Fu
    Antiproliferative activity against human WM266.4 cells after 24 hrs by MTT assay
    Antiproliferative activity against human WM266.4 cells after 24 hrs by MTT assay
    [PMID: 24934992]
    ZR-75-1 GI50
    2.3 μM
    Compound: 5FU
    Growth inhibition of human ZR-75-1 cells after 48 hrs by sulforhodamine B assay
    Growth inhibition of human ZR-75-1 cells after 48 hrs by sulforhodamine B assay
    [PMID: 21489802]
    In Vitro

    5-Fluorouracil (5-Fu) and NSC 123127 (Dox) show synergistic anticancer efficacy. The IC50 value of 5-Fu/Dox-DNM toward human breast cancer (MDA-MB-231) cells is 0.25 μg/mL, presenting an 11.2-fold and 6.1-fold increase in cytotoxicity compared to Dox-DNM and 5-Fu-DNM, respectively[1]. In 5-fluorouracil (5-FU) and CDDP treated NFBD1-inhibited NPC cells, the NFBD1 expression in NPC CNE1 cell lines is depleted using lentivirus-mediated short hairpin RNA, and the sensitivity of these cells is elevated. NFBD1 knockdown leads to an obvious induction of apoptosis in CDDP- or 5-FU-treated CNE1 cells[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    In Vivo

    5-Fluorouracil (23 mg/kg, 3 times/week) for 14 days, induces accelerated gastrointestinal transit associated with acute intestinal inflammation at day 3 after the start of treatment, which may have led to persistent changes in the ENS observed after days 7 and 14 of treatment contributing to delayed gastrointestinal transit and colonic dysmotility[4].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Clinical Trial
    Molecular Weight

    130.08

    Formula

    C4H3FN2O2

    CAS No.
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    O=C(N1)NC=C(F)C1=O

    Structure Classification
    Initial Source
    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage

    4°C, protect from light

    *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

    Solvent & Solubility
    In Vitro: 

    DMSO : 50 mg/mL (384.38 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

    1 M Ammonium hydroxide : 50 mg/mL (384.38 mM; Need ultrasonic)

    H2O : 10 mg/mL (76.88 mM; ultrasonic and warming and heat to 60°C)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 7.6876 mL 38.4379 mL 76.8758 mL
    5 mM 1.5375 mL 7.6876 mL 15.3752 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
    =
    Concentration
    ×
    Volume
    ×
    Molecular Weight *

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

    ×
    Volume (start)

    V1

    =
    Concentration (final)

    C2

    ×
    Volume (final)

    V2

    In Vivo:

    Select the appropriate dissolution method based on your experimental animal and administration route.

    For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
    To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

      Solubility: ≥ 2.5 mg/mL (19.22 mM); Clear solution

      This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

      Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

      Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
    • Protocol 2

      Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

      Solubility: ≥ 2.5 mg/mL (19.22 mM); Clear solution

      This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

      Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

      Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.

    For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  PBS

      Solubility: 25 mg/mL (192.19 mM); Clear solution; Need ultrasonic

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Please enter your animal formula composition:
    %
    DMSO +
    +
    %
    Tween-80 +
    %
    Saline
    Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
    The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
    Calculation results:
    Working solution concentration: mg/mL
    Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).

    *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
    Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
     If the continuous dosing period exceeds half a month, please choose this protocol carefully.
    Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
    Purity & Documentation

    Purity: 99.99%

    References
    Animal Administration
    [2]

    Mice receive intraperitoneal injections of 5-FU (23 mg/kg), 3 times a week via a 26 gauge needle. 5-FU is dissolved in 100% dimethyl sulfoxide (DMSO) to make 1 M/L stock solution refrigerated at −20°C. The stock is then defrosted and diluted with sterile water to make 0.1 M/L (10% DMSO) solutions for intraperitoneal injections. The dose of 5-FU is calculated to be equivalent to standard human dose per body surface area. The low doses of 5-FU (10-40 mg/kg) have been shown to have antitumor efficacy in mouse models of cancer. Sham-treated mice received 10% DMSO in sterile water via intraperitoneal injection three times a week via a 26 gauge needle. The injected volumes are calculated to the body weight; the maximum volume does not exceed 200 μL per injection. Mice are euthanized via cervical dislocation at 3 (2 treatments), 7 (3 treatments), and 14 (6 treatments) days after the first injection and colon is collected for in vitro experiments.

    MCE has not independently confirmed the accuracy of these methods. They are for reference only.

    References

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O / DMSO / 1 M Ammonium hydroxide 1 mM 7.6876 mL 38.4379 mL 76.8758 mL 192.1894 mL
    5 mM 1.5375 mL 7.6876 mL 15.3752 mL 38.4379 mL
    10 mM 0.7688 mL 3.8438 mL 7.6876 mL 19.2189 mL
    15 mM 0.5125 mL 2.5625 mL 5.1251 mL 12.8126 mL
    20 mM 0.3844 mL 1.9219 mL 3.8438 mL 9.6095 mL
    25 mM 0.3075 mL 1.5375 mL 3.0750 mL 7.6876 mL
    30 mM 0.2563 mL 1.2813 mL 2.5625 mL 6.4063 mL
    40 mM 0.1922 mL 0.9609 mL 1.9219 mL 4.8047 mL
    50 mM 0.1538 mL 0.7688 mL 1.5375 mL 3.8438 mL
    60 mM 0.1281 mL 0.6406 mL 1.2813 mL 3.2032 mL
    DMSO / 1 M Ammonium hydroxide 80 mM 0.0961 mL 0.4805 mL 0.9609 mL 2.4024 mL
    100 mM 0.0769 mL 0.3844 mL 0.7688 mL 1.9219 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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