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Results for "

hydroxyquinoline

" in MedChemExpress (MCE) Product Catalog:

28

Inhibitors & Agonists

4

Biochemical Assay Reagents

5

Peptides

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W005598
    2-Hydroxyquinoline

    		Glycosidase Metabolic Disease
    2-Hydroxyquinoline is a potent α-glucosidase inhibitor with IC50 values of 64.4, 130.5 µg/mL for α-glucosidase and α-amylase, respectively. 2-Hydroxyquinoline has the potential for the research of diabetes .
    2-Hydroxyquinoline
  • HY-B1005
    8-Hydroxyquinoline

    8-Quinolinol

    		 Bacterial Antibiotic Cancer
    8-Hydroxyquinoline (8-Quinolinol) is a lipophilic metal chelator that can be used as a fungicide .8-Hydroxyquinoline shows the MIC range of 27.56-55.11 μM (4-8 μg/mL) against the clinical isolates of Neisseria gonorrhoeae. 8-Hydroxyquinoline can bind to copper form complexes and transport copper into cells. 8-Hydroxyquinoline increases in the number of micronucleated polychromatic erythrocytes and can also make hair depigmented in mice .
    8-Hydroxyquinoline
  • HY-W016840
    8-Hydroxyquinoline-2-carbaldehyde

    		Biochemical Assay Reagents Others
    8-Hydroxyquinoline-2-carbaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    8-Hydroxyquinoline-2-carbaldehyde
  • HY-B1005R
    8-Hydroxyquinoline (Standard)

    		Bacterial Antibiotic Cancer
    8-Hydroxyquinoline (Standard) is the analytical standard of 8-Hydroxyquinoline. This product is intended for research and analytical applications. 8-Hydroxyquinoline (8-Quinolinol) is a lipophilic metal chelator that can be used as a fungicide .8-Hydroxyquinoline shows the MIC range of 27.56-55.11 μM (4-8 μg/mL) against the clinical isolates of Neisseria gonorrhoeae. 8-Hydroxyquinoline can bind to copper form complexes and transport copper into cells. 8-Hydroxyquinoline increases in the number of micronucleated polychromatic erythrocytes and can also make hair depigmented in mice .
    8-Hydroxyquinoline (Standard)
  • HY-W012037R
    8-Hydroxyquinoline (hemisulfate) (Standard)

    		Bacterial Antibiotic Infection
    8-Hydroxyquinoline (hemisulfate) (Standard) is the analytical standard of 8-Hydroxyquinoline (hemisulfate). This product is intended for research and analytical applications. 8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.
    8-Hydroxyquinoline (hemisulfate) (Standard)
  • HY-172042
    PB-22 7-Hydroxyquinoline isomer

    		Drug Isomer Neurological Disease
    PB-22 7-Hydroxyquinoline isomer is a structural isomer of PB-22. PB-22 is a cannabinoid.
    PB-22 7-Hydroxyquinoline isomer
  • HY-172040
    PB-22 5-Hydroxyquinoline isomer

    		Drug Isomer Neurological Disease
    PB-22 5-hydroxyquinoline isomer is a structural isomer of PB-22. PB-22 is a cannabinoid.
    PB-22 5-Hydroxyquinoline isomer
  • HY-172041
    PB-22 6-Hydroxyquinoline isomer

    		Drug Isomer Neurological Disease
    PB-22 6-Hydroxyquinoline isomer is a structural isomer of PB-22. PB-22 is a cannabinoid.
    PB-22 6-Hydroxyquinoline isomer
  • HY-172035
    5-Fluoro PB-22 5-hydroxyquinoline isomer

    		Cannabinoid Receptor Neurological Disease
    5-Fluoro PB-22 5-hydroxyquinoline isomer is a synthetic cannabinoid.
    5-Fluoro PB-22 5-hydroxyquinoline isomer
  • HY-172037
    5-Fluoro PB-22 7-hydroxyquinoline isomer

    		Cannabinoid Receptor Neurological Disease
    5-Fluoro PB-22 7-hydroxyquinoline isomer is a synthetic cannabinoid.
    5-Fluoro PB-22 7-hydroxyquinoline isomer
  • HY-W012037
    8-Hydroxyquinoline hemisulfate

    8-Quinolinol hemisulfate

    		 Bacterial Antibiotic Infection
    8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.
    8-Hydroxyquinoline hemisulfate
  • HY-W001023
    5-Amino-8-hydroxyquinoline

    5A8HQ

    		 Proteasome Cancer
    5-Amino-8-hydroxyquinoline (5A8HQ), a potential anticancer candidate, has promising proteasome inhibitory activity.
    5-Amino-8-hydroxyquinoline
  • HY-32100
    5-Hydroxyquinoline

    Quinolin-5(1H)-one

    		 Biochemical Assay Reagents Others
    5-Hydroxyquinoline is an organic compound commonly used in certain chemical reactions and biological research. It can be used in the manufacture of dyes, cellulase, oxidants and passivators, etc., and is widely used in the pigment, paint and rubber industries. In addition, the compound is also used as the precursor, intermediate and metal ion complexing agent of certain drugs.
    5-Hydroxyquinoline
  • HY-139464
    Q134R

    		Nuclear Factor of activated T Cells (NFAT) Neurological Disease
    Q134R, a neuroprotective hydroxyquinoline derivative that suppresses nuclear factor of activated T cell (NFAT) signaling. Q134R can across blood-brain barrier. Q134R has the potential for Alzheimer's disease (AD) and aging-related disorders research .
    Q134R
  • HY-B1400
    Diiodohydroxyquinoline
    1 Publications Verification

    Iodoquinol; 5,7-Diiodo-8-hydroxyquinoline; 5,7-Diiodo-8-quinolinol

    		 Parasite SARS-CoV Infection Inflammation/Immunology
    Diiodohydroxyquinoline (Iodoquinol, 5,7-Diiodo-8-hydroxyquinoline, 5,7-Diiodo-8-quinolinol) has an orally active and satisfactory antiparasitic properties. Diiodohydroxyquinoline exhibits mutagenic potential in mice and potent anti-SARS-CoV-2 activity with an EC50 value of 1.38 μM in VeroE6 cells. Diiodohydroxyquinoline's antimutagen is ascorbic acid. Diiodohydroxyquinoline is promising for research in inflammationin, testinal amebiasis, amebic liver abscess and chronic nonspecific diarrheas .
    Diiodohydroxyquinoline
  • HY-118288
    Aurachin B

    		Parasite Infection
    Aurachin B is an alkaloid with a 3-hydroxyquinoline N-oxide core .
    Aurachin B
  • HY-B0295
    Chloroxine
    1 Publications Verification

    		 Bacterial Antibiotic Parasite Infection
    Chloroxine is one of the important 8-hydroxyquinoline derivative. Chloroxine has effective antibacterial, antifungal, antiprotozoal and antiamoebic activities, especially used in treating the intestinal amebiasis. Chloroxine is also used in the treatment of dandruff and seborrheic dermatitis of the scalp .
    Chloroxine
  • HY-B0295R
    Chloroxine (Standard)

    		Bacterial Antibiotic Parasite Infection
    Chloroxine (Standard) is the analytical standard of Chloroxine. This product is intended for research and analytical applications. Chloroxine is one of the important 8-hydroxyquinoline derivative. Chloroxine has effective antibacterial, antifungal, antiprotozoal and antiamoebic activities, especially used in treating the intestinal amebiasis. Chloroxine is also used in the treatment of dandruff and seborrheic dermatitis of the scalp .
    Chloroxine (Standard)
  • HY-157141
    Antibacterial agent 163

    		Bacterial Infection
    Antibacterial agent 163 (compound 1), a hydroxyquinoline derivative, is a potent bacterial inhibitor. Antibacterial agent 163 inhibits methicillin-resistant Staphylococcus aureus (MRSA) .
    Antibacterial agent 163
  • HY-157142
    Antibacterial agent 165

    		Bacterial Infection
    Antibacterial agent 165 (compound 3), a hydroxyquinoline derivative, is a potent bacterial inhibitor. Antibacterial agent 165 inhibits methicillin-resistant Staphylococcus aureus (MRSA) .
    Antibacterial agent 165
  • HY-B1212
    Broxyquinoline
    1 Publications Verification

    Dibromohydroxyquinoline; 5,7-Dibromo-8-hydroxyquinoline

    		 Parasite Influenza Virus Infection
    Broxyquinoline (Dibromohydroxyquinoline) is an effective inhibitor of severe fever with thrombocytopenia syndrome virus (SFTSV) with an IC50 of 5.8 µM. Additionally, Broxyquinoline is an inhibitor of CpACBP1 with an IC50 of 64.9 μM. CpACBP1 is a fatty acyl-CoA binding protein of Cryptosporidium parvum, thus Broxyquinoline has the potential to inhibit parasite growth. Broxyquinoline shows promise for research in the field of infectious diseases .
    Broxyquinoline
  • HY-W008992
    Quinolin-8-ol sulfate hydrate

    8-hydroxyquinoline sulfate hydrate

    		 Biochemical Assay Reagents Others
    Quinolin-8-ol sulfate hydrate is an organic compound commonly used in dyes and as a raw material for chemical analysis. It can cooperate with metal ions to form dyes, and is widely used in the fields of dyes, printing and textile manufacturing. In addition, the compound also has good toxicity and biocompatibility, and is also used in some medical fields.
    Quinolin-8-ol sulfate hydrate
  • HY-172036
    5-Fluoro PB-22 6-hydroxyquinoline isomer

    		Drug Isomer Neurological Disease
    5-Fluoro PB-22 N-(3-fluoropentyl) isomer is a structural isomer of 5-Fluoro PB-22.
    5-Fluoro PB-22 6-hydroxyquinoline isomer
  • HY-12304
    IOX1
    Maximum Cited Publications
    11 Publications Verification

    		 Histone Demethylase Cancer
    IOX1, 5-Carboxy-8-hydroxyquinoline, is a potent broad‐spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases. IOX1 inhibits KDM4C, KDM4E, KDM2A, KDM3A and KDM6B with IC50 values of 0.6 μM, 2.3 μM, 1.8 μM, 0.1 μM and 1.4 μM, respectively . IOX1 also inhibits ALKBH5 .
    IOX1
  • HY-B1400R
    Diiodohydroxyquinoline (Standard)

    		Parasite SARS-CoV Infection Inflammation/Immunology
    Diiodohydroxyquinoline (Standard) is the analytical standard of Diiodohydroxyquinoline. This product is intended for research and analytical applications. Diiodohydroxyquinoline (Iodoquinol, 5,7-Diiodo-8-hydroxyquinoline, 5,7-Diiodo-8-quinolinol) has an orally active and satisfactory antiparasitic properties. Diiodohydroxyquinoline exhibits mutagenic potential in mice and potent anti-SARS-CoV-2 activity with an EC50 value of 1.38 μM in VeroE6 cells. Diiodohydroxyquinoline's antimutagen is ascorbic acid. Diiodohydroxyquinoline is promising for research in inflammationin, testinal amebiasis, amebic liver abscess and chronic nonspecific diarrheas .
    Diiodohydroxyquinoline (Standard)
  • HY-158104
    LPPM-8

    		ATF6 Others
    LPPM-8 is a ligand of Med25 and an inhibitor of Med25 protein-protein interactions (PPIs). LPPM-8 engages Med25 through interaction with the H2 face of its Activator Interaction Domain and stabilizes full-length protein in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcriptional activators (such as ATF6a). LPPM-8 can be used for studying Med25 and Mediator complex biology .
    LPPM-8
  • HY-P3100
    Orfamide A

    		Parasite Infection
    Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC50 value of 34.5 μg/mL .
    Orfamide A
  • HY-P10447
    Plipastatin A1

    Fengycin IX; SNA-60-367-3

    		 Phospholipase Inflammation/Immunology
    Plipastatin A1 is a lipopeptide with enzyme inhibitory and immunosuppressive activities. Plipastatin A1 is found in Bacillus cereus and inhibits phospholipase A2 (PLA2), PLC, and PLD .
    Plipastatin A1

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