Plipastatin A1  (Synonyms: Fengycin IX; SNA-60-367-3)

Plipastatin A1 is a lipopeptide with enzyme inhibitory and immunosuppressive activities. Plipastatin A1 is found in Bacillus cereus and inhibits phospholipase A2 (PLA2), PLC, and PLD^[1].

1463.71

C₇₂H₁₁₀N₁₂O₂₀

103651-09-8

{(3R)-3-hydroxy-1-oxohexadecyl}-Glu-{d-Orn}-Tyr-{d-Thr}-Glu-{d-Ala}-Pro-Gln-{d-Tyr}-Ile (Lactam bridge: Tyr3-Ile10)

{(3R)-3-hydroxy-1-oxohexadecyl}-E-{d-Orn}-Y{d-Thr}-E-{d-Ala}-PQ{d-Tyr}-I (Lactam bridge: Tyr3-Ile10)

O=C1N2[C@](CCC2)([H])C(N[C@H](C(N[C@@H](C(N[C@@](C(OC3=CC=C(C[C@@H](C(N[C@](C(N[C@H](C(N[C@@H]1C)=O)CCC(O)=O)=O)([H])[C@H](O)C)=O)NC([C@@H](CCCN)NC([C@H](CCC(O)=O)NC(C[C@H](O)CCCCCCCCCCCCC)=O)=O)=O)C=C3)=O)([H])[C@@H](C)CC)=O)CC4=CC=C(C=C4)O)=O)CCC(N)=O)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Honma M, et al. Termination of the structural confusion between plipastatin A1 and fengycin IX. Bioorg Med Chem. 2012 Jun 15;20(12):3793-8.  [Content Brief]