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Results for "

lipid metabolism-related disease

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Fatty Acid Synthase (FASN) (1) Fluorescent Dye (1) Sirtuin (1)
By Research Areas:	Cancer (1) Metabolic Disease (2)
Click Chemistry:	Alkynes (1)

Inhibitors & Agonists

Screening Libraries

Click Chemistry

Targets Recommended: Mitochondrial Metabolism Interleukin Related Oxysterol-binding Protein-related Protein (ORP) Mas-related G-protein-coupled Receptor (MRGPR) Trk Receptor ROR NEKs Kallikrein Atg4 CGRP Receptor RUNX Atg8/LC3 Arp2/3 Complex ATM/ATR sFRP-1 Neuropeptide S Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-16100

BI 99179 1 Publications Verification	Fatty Acid Synthase (FASN)	Metabolic Disease Cancer
BI 99179 is a potent and selective type I fatty acid synthase (FAS) inhibitor with an IC₅₀ of 79 nM. BI 99179 is a tool compound suitable for the in vivo validation of FAS as a target for lipid metabolism related diseases. BI 99179 exhibits significant exposure (both peripheral and central) upon oral administration in rats .

HY-169159

SIRT6 activator 2	Sirtuin	Metabolic Disease
SIRT6 activator 2 (compound 31) is a sirtuin 6 activator with anti-lipid accumulation properties. SIRT6 activator 2 significantly downregulates LXR, SREBP-1c, and their target genes associated with lipogenesis, and can be used for research related to lipid metabolism-related diseases .

HY-117072

(E)-2-Hexadecenal alkyne	Fluorescent Dye	Others
(E)-2-Hexadecenal alkyne (compound 2) is a chemical probe used to explore the cellular targets of 2-trans-Hexadecenal. It can covalently modify multiple proteins in cells and provide a tool for studying lipid metabolism-related diseases.

Cat. No.	Product Name

HY-L182

Fatty Acids Compound Library	295 compounds
Fatty acids (FAs) are the main components of lipids. The synthesis of fatty acids mainly involves the Triglyceride (TG) cycle and De Novo Lipogenesis (DNL). Fatty acids which exist widely in organisms are components of cell membranes and play an indispensable role in cell signaling. In addition, FFAs can be taken up from circulating plasma by all mitochondria-containing cells, and they are metabolized by β-oxidation and the citric acid cycle to release large amounts of energy in the form of ATP. Abnormal fatty acid metabolism is associated with the occurrence and development of cardiovascular diseases, diabetes, fatty liver, hyperthyroidism, and other diseases. MCE offers a unique collection of fatty acid compounds. Fatty Acids Compound Library is an important tool for the study of energy metabolism and drug development of metabolism-related diseases.

Fatty Acids Compound Library

295 compounds

Fatty acids (FAs) are the main components of lipids. The synthesis of fatty acids mainly involves the Triglyceride (TG) cycle and De Novo Lipogenesis (DNL). Fatty acids which exist widely in organisms are components of cell membranes and play an indispensable role in cell signaling. In addition, FFAs can be taken up from circulating plasma by all mitochondria-containing cells, and they are metabolized by β-oxidation and the citric acid cycle to release large amounts of energy in the form of ATP. Abnormal fatty acid metabolism is associated with the occurrence and development of cardiovascular diseases, diabetes, fatty liver, hyperthyroidism, and other diseases.

MCE offers a unique collection of fatty acid compounds. Fatty Acids Compound Library is an important tool for the study of energy metabolism and drug development of metabolism-related diseases.

Cat. No.	Product Name		Classification

HY-117072

(E)-2-Hexadecenal alkyne		Alkynes
(E)-2-Hexadecenal alkyne (compound 2) is a chemical probe used to explore the cellular targets of 2-trans-Hexadecenal. It can covalently modify multiple proteins in cells and provide a tool for studying lipid metabolism-related diseases.

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