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Results for "

radiotracers

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (1) Adenosine Receptor (1) Amyloid-β (2) Biochemical Assay Reagents (2) c-Fms (1) CDK (1) CXCR (1) Dopamine Receptor (3) FAP (7) GSK-3 (1) Integrin (1) LPL Receptor (1) mAChR (1) MMP (1) Opioid Receptor (1) PD-1/PD-L1 (1) Radionuclide-Drug Conjugates (RDCs) (1) Tau Protein (2)
By Research Areas:	Cancer (15) Cardiovascular Disease (3) Inflammation/Immunology (1) Neurological Disease (9)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-106450

Binodenoson MRE-0470; WRC 0470	Adenosine Receptor	Cardiovascular Disease
Binodenoson (MRE-0470) is a potent and selective A2A adenosine receptor agonist (K_D=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stress imaging .

HY-137331

FAPI-46 1 Publications Verification	FAP	Cancer
FAPI-46 is a quinoline-based fibroblast activation protein (FAP)-targeted radiotracer. FAPI-46 has higher tumor uptake and prolonged tumor accumulation. FAPI-46 can be used for tumor imaging of a multitude of different cancers .

HY-153552A

NH2-UAMC1110 TFA	FAP	Cancer
NH2-UAMC1110 TFA is a UAMC1110 derivative that can be used in the synthesis of FAPI-QS. UAMC1110 is a fibroblast activation protein (FAP) inhibitor. FAPI-QS is a chelating agent that can be used to synthesize high tumor selectivity and high dose radiotracers for the diagnosis and treatment of tumors .

HY-101183

THK5351	Tau Protein	Neurological Disease
THK5351 can be radiolabeled and used as a radiotracer for in vivo imaging of tau pathology in the brain.

HY-W700684

N-Didesmethyl Loperamide R 21345	Others	Others
N-Didesmethyl Loperamide is a metabolite of Loperamide; a new and improved PET radiotracer for imaging P-gp function.

HY-D2310

CXCR2 Probe 1	CXCR	Inflammation/Immunology
CXCR2 Probe 1 (Compound ^[18F]16b) is a selective ligand for CXCR2 and is a radiotracer for PET imaging of neutrophils in inflammatory diseases .

HY-100723

THK-523	Amyloid-β	Neurological Disease
THK-523 has demonstrated its high affinity and selectivity for tau pathology both in vitro and in vivo. ¹⁸F-THK523 is a potent tau imaging radiotracer.? ¹⁸F-THK523 is a potent in vivo tau imaging ligand for Alzheimer's disease .

HY-D2281

[99mTc]Tc-6–1	FAP	Cancer
[99m Tc]Tc-6-1, a ^99mTc-labeled FAPI-46 derivative, is a specific fibroblast activation protein (FAP)-targeted radiotracer. [99m Tc]Tc-6-1 exhibits good tumor uptake and acts as a promising molecular tracer for FAP tumor imaging .

HY-146102

M1 ligand 1	mAChR	Others
M1 ligand 1 (compound 3b-b) is a muscarinic acetylcholine receptor M1 ligand. M1 ligand 1 is a N-desmethyl congener of arecoline derivative. M1 ligand 1 can be used as PET (positron emission tomography) radiotracer .

HY-D2311

CDK19 Probe 1	CDK	Cancer
CDK19 Probe 1 (Compound 10c) is a CDK19 inhibitor (IC₅₀: 1.01 μM) and can be used for cancer research .

HY-164316A

FT-FAPI-12_9 TFA	FAP	Cancer
FT-FAPI-12_9 (TFA) is an FAP ligand that can be used for the synthesis of the FAP-targeted radiotracer FAPI-46 (HY-137331) .

HY-163327

pFBC	Others	Neurological Disease
pFBC ([ ¹⁸F]pEBC) is a covalent CLIP-tag radiotracer for detection of viral reporter gene transfer in the murine brain. pFBC can be used in neurobiological research .

HY-164316

FT-FAPI-12_9	FAP	Cancer
FT-FAPI-12_9 is a FAP-binding moiety, which can be used for synthesis of FAP-targeted radiotracer FAPI-46 (HY-137331) .

HY-145128

GR103545	Opioid Receptor	Neurological Disease
GR103545 is a potent and selective agonist of the κ-opioid receptor (κ-OR). ¹¹GR103545 is a radiotracer for imaging κ-OR in vivo ^[1]

HY-129059

Odapipam 1 Publications Verification NNC 756	Dopamine Receptor	Neurological Disease
Odapipam (NNC 756) is a selective, high affinity and benzazepine dopamine D₁ receptor antagonist with a K_d of 0.18 nM. Odapipam is also a superior positron emission tomography (PET) radiotracer .

HY-149219

BIBD-124	Amyloid-β	Neurological Disease
BIBD-124 binds amyloid beta (Aβ) plaque with an IC₅₀ value of 9.51 nM. [18F]BIBD-124 can be used as radiotracer of Aβ plaques .

HY-135497

Fallypride	Dopamine Receptor	Neurological Disease
Fallypride is a potent antagonist of dopamine D2/D3 receptor. Fallypride, in the form of fallypride ( ¹⁸F), can be used as a positron emission tomography (PET) radiotracer .

HY-154868

MMP-13-IN-1	MMP	Cardiovascular Disease Cancer
MMP-13-IN-1 is a potent and selective inhibitor of MMP-13 with a IC₅₀ value of 16 nM. MMP-13-in-1 can be used for atherosclerosis research .

HY-P3440

WL12	Radionuclide-Drug Conjugates (RDCs) PD-1/PD-L1	Cancer
WL12 is a specifically targeting programmed death ligand 1 (PD-L1) binding peptide. WL12 can be radiolabeled by different radionuclides, generating radiotracers, which can assess the tumor PD-L1 expression .

HY-153552

NH2-UAMC1110	Others	Cancer
NH2-UAMC1110 is a UAMC1110 derivative that can be used in the synthesis of FAPI-QS. FAPI-QS is a chelating agent that can be used to manufacture high tumor selectivity and high dose radiotracers for the diagnosis and treatment of tumors .

HY-128890B

DOTA-NHS-ester TFA 1 Publications Verification	ADC Linker Biochemical Assay Reagents	Cancer
DOTA-NHS-ester (TFA) is used as a linker for affibody molecules, and it can be employed in small animal positron emission tomography (PET), single photon emission computed tomography (SPECT), and CT scanning. DOTA-NHS-ester can be used to label radiotracers or imaging probes for tumor detection .

HY-101185

T808	Tau Protein	Neurological Disease
T808 is a tau-selective Alzheimer’s PET ligand. T808 is a type of imaging agent used in positron emission tomography (PET) scans. It is a radiotracer that is used to help visualize certain areas of the body, such as the brain, in order to diagnose and monitor various medical conditions .

HY-158243

Fallypride precursor	Dopamine Receptor	Neurological Disease
Fallypride precursor (Compound 15) can be used for synthesis of Fallypride (HY-135497). Fallypride is an antagonist of the dopamine D2/D3 receptor. Fallypride can be used as a positron emission tomography (PET) radiotracer when labeled with ¹⁸F .

HY-161676

DOTA-RBB-Ga	Others	Others
DOTA-RBB-Ga is a conjugate of a chelator DOTA, an inhibitor for CDK4/6 Ribociclib (HY-15777) and a gallium. DOTA-RBB-Ga can be used as a PET radiotracer for CDK4/6 positive tumor, when labeled with radioactive gallium ⁶⁸Ga .

HY-149860

FAP-IN-1	FAP	Cancer
FAP-IN-1 is a fibroblast activation protein (FAP) inhibitor with an IC₅₀ value of 3.3 nM. FAP-IN-1 can be used for the research of cancer .

HY-163075

SYB4	Others	Others
SYB4 (compound 5) is a PET tracer which suitable for imaging the Sigma-2 Receptor in the brain of nonhuman primates .

HY-107531

A 1070722	GSK-3	Cancer
A 1070722 is a potent and selective glycogen synthase kinase 3 (GSK-3) inhibitor, with a K_i of 0.6 nM for both GSK-3α and GSK-3β. A 1070722 can penetrate the blood-brain barrier (BBB) and accumulates in brain regions, thus potential for PET radiotracer for the quantification of GSK-3 in brain .

HY-100133A

DOTA-ADIBO TFA	Integrin	Cancer
DOTA-ADIBO TFA is a DOTA-derived bifunctional chelator (BFC) that allows drug conjugation via an uncatalyzed, copper-free cycloaddition reaction. DOTA-ADIBO TFA enables the construction of fusion chelator systems that can be further used to synthesize radiotracers after Cu[64] modification. Positron emission tomography imaging of tumors expressing integrin αvβ6 .

HY-149210

S1PR1 Radioligand 1	LPL Receptor	Others
S1PR1 Radioligand 1(compound 6 h) is a specific S1PR1 radioligand with IC₅₀ = 8.7 nM. S1PR1 Radioligand 1 has good brain uptake and can be used as a S1PR1-specific F-18 radiotracer for studying the function of S1PR1 in brain diseases .

HY-159108

AZ683	c-Fms	Cardiovascular Disease
AZ683 is a potent and selective 3-amido-4-anilinoquinoline CSF1R inhibitor. AZ683 has high affinity for CSF1R (K_i=8 nM; IC₅₀=6 nM). AZ683 has good oral bioavailability. [ ¹¹C]AZ683 can be used as a positron emission tomography (PET) radiotracer for colony stimulating factor 1 receptor (CSF1R) .

HY-W095635

Tetramethylammonium fluoride tetrahydrate	Biochemical Assay Reagents	Others
Tetramethylammonium fluoride tetrahydrate (TMAF) is a quaternary ammonium salt. TMAF is commonly used as a weak base and a source of fluoride ions in various organic reactions, including nucleophilic substitution, functional group deprotection, and ring-opening polymerization. Unlike other fluoride sources, TMAF is compatible with many functional groups, making it a versatile tool in synthetic chemistry. Functional reagents, In addition, TMAF has been used as a fluorinating agent in medicinal chemistry, for the preparation of radiotracers and protein modification in biochemistry, and the tetrahydrate form of TMAF is more stable and easier to handle than the anhydrous form.

HY-128643

FAPI-4 Maximum Cited Publications 21 Publications Verification	FAP	Cancer
FAPI-4 is a potent fibroblast activation protein (FAP) inhibitor for the targeting FAP. FAPI-4 can be used in cancer research. ⁶⁸Ga-FAPI-4 PET/CT is a promising new diagnostic method for imaging various kinds of cancer, with good tumor-to-background contrast ratios .

Cat. No.	Product Name	Type

HY-D2310

CXCR2 Probe 1	Dyes
CXCR2 Probe 1 (Compound ^[18F]16b) is a selective ligand for CXCR2 and is a radiotracer for PET imaging of neutrophils in inflammatory diseases .

HY-D2281

[99mTc]Tc-6–1	Dyes
[99m Tc]Tc-6-1, a ^99mTc-labeled FAPI-46 derivative, is a specific fibroblast activation protein (FAP)-targeted radiotracer. [99m Tc]Tc-6-1 exhibits good tumor uptake and acts as a promising molecular tracer for FAP tumor imaging .

HY-D2311

CDK19 Probe 1	Dyes
CDK19 Probe 1 (Compound 10c) is a CDK19 inhibitor (IC₅₀: 1.01 μM) and can be used for cancer research .

Cat. No.	Product Name	Type

HY-101183

THK5351	Indicators
THK5351 can be radiolabeled and used as a radiotracer for in vivo imaging of tau pathology in the brain.

HY-W095635

Tetramethylammonium fluoride tetrahydrate	Biochemical Assay Reagents
Tetramethylammonium fluoride tetrahydrate (TMAF) is a quaternary ammonium salt. TMAF is commonly used as a weak base and a source of fluoride ions in various organic reactions, including nucleophilic substitution, functional group deprotection, and ring-opening polymerization. Unlike other fluoride sources, TMAF is compatible with many functional groups, making it a versatile tool in synthetic chemistry. Functional reagents, In addition, TMAF has been used as a fluorinating agent in medicinal chemistry, for the preparation of radiotracers and protein modification in biochemistry, and the tetrahydrate form of TMAF is more stable and easier to handle than the anhydrous form.

Tetramethylammonium fluoride tetrahydrate

Biochemical Assay Reagents

Tetramethylammonium fluoride tetrahydrate (TMAF) is a quaternary ammonium salt. TMAF is commonly used as a weak base and a source of fluoride ions in various organic reactions, including nucleophilic substitution, functional group deprotection, and ring-opening polymerization. Unlike other fluoride sources, TMAF is compatible with many functional groups, making it a versatile tool in synthetic chemistry. Functional reagents, In addition, TMAF has been used as a fluorinating agent in medicinal chemistry, for the preparation of radiotracers and protein modification in biochemistry, and the tetrahydrate form of TMAF is more stable and easier to handle than the anhydrous form.

HY-100133A

DOTA-ADIBO TFA	Chelators
DOTA-ADIBO TFA is a DOTA-derived bifunctional chelator (BFC) that allows drug conjugation via an uncatalyzed, copper-free cycloaddition reaction. DOTA-ADIBO TFA enables the construction of fusion chelator systems that can be further used to synthesize radiotracers after Cu[64] modification. Positron emission tomography imaging of tumors expressing integrin αvβ6 .

Cat. No.	Product Name	Target	Research Area

HY-P3440

WL12	Radionuclide-Drug Conjugates (RDCs) PD-1/PD-L1	Cancer
WL12 is a specifically targeting programmed death ligand 1 (PD-L1) binding peptide. WL12 can be radiolabeled by different radionuclides, generating radiotracers, which can assess the tumor PD-L1 expression .

HY-P10734

NODAGA-RGD	Peptides
NODAGA-RGD is a peptide that can be radiolabeled and used as a radiotracer for positron emission tomography (PET) diagnosis .

HY-P10023

Evuzamitide	Peptides	Cancer
Evuzamitide is a diagnostic imaging agent. Evuzamitide as a pan-amyloid radiotracer binding to amyloid deposits from multiple amyloidogenic proteins. Evuzamitide can be used for the research of early diagnosis of amyloid cardiomyopathy (CMP) and monitoring .

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