2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. Odapipam

Odapipam (NNC 756) is a selective, high affinity and benzazepine dopamine D1 receptor antagonist with a Kd of 0.18 nM. Odapipam is also a superior positron emission tomography (PET) radiotracer.

For research use only. We do not sell to patients.

Odapipam Chemical Structure

Odapipam Chemical Structure

CAS No. : 131796-63-9

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Based on 1 publication(s) in Google Scholar

Odapipam Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Odapipam

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Dopamine Receptor D1 Receptor D2 Receptor D3 Receptor D4 Receptor D5 Receptor

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  • Purity & Documentation

  • References

  • Customer Review

Description

Odapipam (NNC 756) is a selective, high affinity and benzazepine dopamine D1 receptor antagonist with a Kd of 0.18 nM. Odapipam is also a superior positron emission tomography (PET) radiotracer[1][2].

IC50 & Target

Dopamine D1 receptor[1]
In Vivo

The metabolism of Odapipam has been studied with phenobarbital-induced rat liver microsomes. During the incubation of Odapipam, five different metabolites are formed. The electron-ionization (EI+) mass spectra of the metabolites indicated the formation of N-desmethyl-Odapipam, 1-hydroxy-Odapipam, the two isomers of 3′-hydroxy-Odapipam and a metabolite which is dehydrogenated in the dihydrobenzofuran moiety[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

329.82

Formula

C19H20ClNO2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC1=C(Cl)C=C2CCN(C)C[C@H](C3=C(OCC4)C4=CC=C3)C2=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥99.0%

COA (258 KB)

Handling Instructions (2659 KB)
References
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Odapipam Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Odapipam131796-63-9NNC 756NNC756NNC-756Dopamine ReceptorInhibitorinhibitorinhibit

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