DOTA-NHS-ester TFA

Cat. No.: HY-128890B Purity: ≥95.0%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

DOTA-NHS-ester (TFA) is used as a linker for affibody molecules, and it can be employed in small animal positron emission tomography (PET), single photon emission computed tomography (SPECT), and CT scanning. DOTA-NHS-ester can be used to label radiotracers or imaging probes for tumor detection.

For research use only. We do not sell to patients.

DOTA-NHS-ester TFA Chemical Structure

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of DOTA-NHS-ester TFA:

DOTA-NHS-ester Get quote
DOTA-NHS-ester hexafluorophosphate TFA Get quote

1 Publications Citing Use of MCE DOTA-NHS-ester TFA

•Adv Nanobiomed Res. 2023 Sep 3.

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

615.51

Formula

C₂₂H₃₂F₃N₅O₁₂

Appearance

Solid

Color

White to off-white

SMILES

OC(C(F)(F)F)=O.O=C(ON1C(CCC1=O)=O)CN2CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (203.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6247 mL	8.1233 mL	16.2467 mL
5 mM	0.3249 mL	1.6247 mL	3.2493 mL
10 mM	0.1625 mL	0.8123 mL	1.6247 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥95.0%

Select Batch:

Data Sheet (271 KB) SDS (251 KB)

COA (249 KB) HNMR (285 KB) MS (72 KB)

Handling Instructions (2659 KB)

References

[1]. Hoppmann S, et al. Radiolabeled affibody-albumin bioconjugates for HER2-positive cancer targeting. Bioconjug Chem. 2011 Mar 16;22(3):413-21. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.6247 mL	8.1233 mL	16.2467 mL	40.6167 mL
	5 mM	0.3249 mL	1.6247 mL	3.2493 mL	8.1233 mL
	10 mM	0.1625 mL	0.8123 mL	1.6247 mL	4.0617 mL
	15 mM	0.1083 mL	0.5416 mL	1.0831 mL	2.7078 mL
	20 mM	0.0812 mL	0.4062 mL	0.8123 mL	2.0308 mL
	25 mM	0.0650 mL	0.3249 mL	0.6499 mL	1.6247 mL
	30 mM	0.0542 mL	0.2708 mL	0.5416 mL	1.3539 mL
	40 mM	0.0406 mL	0.2031 mL	0.4062 mL	1.0154 mL
	50 mM	0.0325 mL	0.1625 mL	0.3249 mL	0.8123 mL
	60 mM	0.0271 mL	0.1354 mL	0.2708 mL	0.6769 mL
	80 mM	0.0203 mL	0.1015 mL	0.2031 mL	0.5077 mL
	100 mM	0.0162 mL	0.0812 mL	0.1625 mL	0.4062 mL