2. Immunology/Inflammation
  3. FAP
  4. [99mTc]Tc-6–1

[99m Tc]Tc-6-1, a 99mTc-labeled FAPI-46 derivative, is a specific fibroblast activation protein (FAP)-targeted radiotracer. [99m Tc]Tc-6-1 exhibits good tumor uptake and acts as a promising molecular tracer for FAP tumor imaging.

For research use only. We do not sell to patients.

[99mTc]Tc-6–1 Chemical Structure

[99mTc]Tc-6–1 Chemical Structure

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[99mTc]Tc-6–1 Related Antibodies

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Description

[99m Tc]Tc-6-1, a 99mTc-labeled FAPI-46 derivative, is a specific fibroblast activation protein (FAP)-targeted radiotracer. [99m Tc]Tc-6-1 exhibits good tumor uptake and acts as a promising molecular tracer for FAP tumor imaging[1].

In Vitro

[99mTc]Tc-6-1 exhibits high target-to-nontarget ratios (tumor/blood: 6.06; tumor/muscle: 10.26) and good tumor uptake (16.15% ID/g), which also has significantly high affinity for FAP[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

[99mTc]Tc-6–1 Related Antibodies
Molecular Weight

921.95

Formula

C43H46F2N11NaO7S
SMILES

O=C(C1=CC=NC2=CC=C(C=C21)N(CCCN3CCN(CC3)C([C@@H]4CCCN4C(C5=CN=C(C=C5)N/N=C/C6=C(C=CC=C6)S(=O)(O[Na])=O)=O)=O)C)NCC(N7CC(F)(C[C@]7(C#N)[H])F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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[99mTc]Tc-6–1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[99mTc]Tc-6–1FAPFibroblast activation proteinFAP radiotracerFAPI-4699mTcgood tumor uptake FAP tumor imagingInhibitorinhibitorinhibit

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