FT-FAPI-12_9

Cat. No.: HY-164316 Purity: 95.29%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

FT-FAPI-12_9 is a FAP-binding moiety, which can be used for synthesis of FAP-targeted radiotracer FAPI-46 (HY-137331).

For research use only. We do not sell to patients.

FT-FAPI-12_9 Chemical Structure

CAS No. : 2883407-81-4

Size	Price	Stock	Quantity
5 mg	USD 170	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 280	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 560	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 900	In-stock	Estimated Time of Arrival: December 31
100 mg		Get quote
200 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

Other Forms of FT-FAPI-12_9:

FT-FAPI-12_9 TFA Get quote

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Description

FT-FAPI-12_9 is a FAP-binding moiety, which can be used for synthesis of FAP-targeted radiotracer FAPI-46 (HY-137331)^[1].

Molecular Weight

499.56

Formula

C₂₅H₃₁F₂N₇O₂

CAS No.

2883407-81-4

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(N1[C@@H](CC(F)(C1)F)C#N)CNC(C2=CC=NC3=C2C=C(N(C)CCCN4CCNCC4)C=C3)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (250.22 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0018 mL	10.0088 mL	20.0176 mL
5 mM	0.4004 mL	2.0018 mL	4.0035 mL
10 mM	0.2002 mL	1.0009 mL	2.0018 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 95.29%

Select Batch:

Data Sheet (267 KB) SDS (251 KB)

COA (246 KB) HNMR (272 KB) LCMS (97 KB)

Handling Instructions (2659 KB)

References

[1]. Jaafar Thiel, et al., Fibroblast activation protein (fap) inhibitors, fap conjugates, and diagnostic and therapeutic uses thereof. WO2024064968 A1

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.0018 mL	10.0088 mL	20.0176 mL	50.0440 mL
	5 mM	0.4004 mL	2.0018 mL	4.0035 mL	10.0088 mL
	10 mM	0.2002 mL	1.0009 mL	2.0018 mL	5.0044 mL
	15 mM	0.1335 mL	0.6673 mL	1.3345 mL	3.3363 mL
	20 mM	0.1001 mL	0.5004 mL	1.0009 mL	2.5022 mL
	25 mM	0.0801 mL	0.4004 mL	0.8007 mL	2.0018 mL
	30 mM	0.0667 mL	0.3336 mL	0.6673 mL	1.6681 mL
	40 mM	0.0500 mL	0.2502 mL	0.5004 mL	1.2511 mL
	50 mM	0.0400 mL	0.2002 mL	0.4004 mL	1.0009 mL
	60 mM	0.0334 mL	0.1668 mL	0.3336 mL	0.8341 mL
	80 mM	0.0250 mL	0.1251 mL	0.2502 mL	0.6256 mL
	100 mM	0.0200 mL	0.1001 mL	0.2002 mL	0.5004 mL

FT-FAPI-12_9 Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FT-FAPI-12_92883407-81-4FAPFibroblast activation proteinInhibitorinhibitorinhibit

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