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Results for "

vanin-1

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

3

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-146412
    Vanin-1-IN-3

    		Pantetheinase Metabolic Disease
    Vanin-1-IN-3 (OMP-7) is a vanin-1 inhibitor with an IC50 of 0.038 μM [1].
    Vanin-1-IN-3
  • HY-129035
    PFI-653

    vanin-1-IN-1

    		 Pantetheinase Metabolic Disease Inflammation/Immunology
    PFI-653 (Vanin-1-IN-1) is an inhibitor of vanin-1 enzyme which is a cell surface associated, giycosyiphosphatidyS inositol (GPi) anchored protein and plays an important role in metabolism and inflammation [1].
    PFI-653
  • HY-18780
    RR6
    2 Publications Verification

    		 Pantetheinase Cancer
    RR6 is a potent, selective, reversible, competitive and orally active vanin inhibitor with an IC50 of 540 nM for recombinant vanin-1. RR6 also potently inhibits human, bovine and rat serum pantetheinase with IC50 values of 40 nM, 41 nM and 87 nM, respectively [1].
    RR6
  • HY-161249
    Vanin-1-IN-4

    		Pantetheinase Inflammation/Immunology
    Vanin-1-IN-4 (compound (S)-1) is vanin-1 inhibitor with a chiral methyl substituent, with profils as potent drug-candidate but exist as an amorphous solid [1].
    Vanin-1-IN-4
  • HY-145316
    Vanin-1-IN-2

    		Pantetheinase Metabolic Disease
    Vanin-1-IN-2 is a potent vanin-1 inhibitor with an IC50 of 162 nM. Vanin-1 is a cell-surface-associated, glycosylphosphatidyl inositol (GPI)-anchored protein which is expressed at high levels in the kidney, liver, and small intestine [1].
    Vanin-1-IN-2
  • HY-169491
    Pantothenate-AMC

    		Fluorescent Dye Metabolic Disease
    Pantothenate-AMC is a fluorogenic substrate used for detecting the enzymatic activity of vanin-1, an enzyme involved in the recycling of L-pantothenic acid. Upon enzymatic cleavage by vanin-1, 7-amino-7-methylcoumarin (AMC) is released, and its fluorescence can be used to quantify vanin-1 activity. The excitation/emission maxima of AMC are 340-360 nm and 440-460 nm, respectively [1].
    Pantothenate-AMC
  • HY-149594
    CL-Pa

    		Pantetheinase Metabolic Disease
    CL-Pa is a chemiluminescent probe suitable for detection of urinary Vanin-1. CL-Pa can be used to detect drug-induced acute kidney injury (AKI) through urinalysis [1].
    CL-Pa
  • HY-159986
    X-17

    		Pantetheinase Cancer
    X-17 is a Vanin-1 Inhibitor with potent anti-inflammatory and antioxidant activities. X-17 repressrs the inflammatory factor expressions and myeloperoxidase activity, elevats the colonic glutathione reserve, and restors the intestinal barrier [1].
    X-17

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