2. TGF-beta/Smad
  3. TGF-β Receptor
  4. TGFβRI-IN-6

TGFβRI-IN-6 is a potent TGFβRI inhibitor, with an IC50 of 0.55 nM. TGFβRI-IN-6 has the potential to enhance antitumor immunity.

For research use only. We do not sell to patients.

TGFβRI-IN-6 Chemical Structure

TGFβRI-IN-6 Chemical Structure

CAS No. : 2072051-04-6

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TGFβRI-IN-6 Related Antibodies

Top Publications Citing Use of Products

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ALK1 ALK2 ALK3 ALK4 ALK5 ALK6 ALK7 TGFβR2 ACVR2A ACVR2B

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In Vitro

TGFβRI-IN-6 (compound 22) inhibits TGFβRI, with a Ki of 0.22 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

TGFβRI-IN-6 Related Antibodies
Molecular Weight

374.30

Formula

C17H10F4N6
CAS No.
SMILES

FC1=CN=CC=C1NC2=C(C=CN3)C3=NC(C4=NC(C(F)(F)F)=CC=C4)=N2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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TGFβRI-IN-6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TGFβRI-IN-62072051-04-6TGF-β ReceptorTransforming growth factor beta receptorsInhibitorinhibitorinhibit

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