2. Anti-infection
  3. Antibiotic
  4. Waldiomycin

Waldiomycin is an antibiotic that can be isolated from Streptomyces sp. MK844-mF10 that has inhibitory effects on low GC-content Gram-positive bacteria. Waldiomycin inhibits the activity of WalK kinase by targeting its ATP-binding domain, thereby blocking the WalK/WalR signal transduction system, which plays a role in cell growth and division.

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Waldiomycin Chemical Structure

Waldiomycin Chemical Structure

CAS No. : 1342200-33-2

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Waldiomycin Related Antibodies

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Description

Waldiomycin is an antibiotic that can be isolated from Streptomyces sp. MK844-mF10 that has inhibitory effects on low GC-content Gram-positive bacteria. Waldiomycin inhibits the activity of WalK kinase by targeting its ATP-binding domain, thereby blocking the WalK/WalR signal transduction system, which plays a role in cell growth and division[1][2].

Molecular Weight

702.70

Formula

C38H38O13
CAS No.
SMILES

O=C1C2=C(C(C3=C(O)C([C@@H]4O[C@@H]([C@H](CC4)OC(/C=C/C=C/C=C/[C@@H]5O[C@](C)(O[C@H]5C)C(O)=O)=O)C)=CC=C31)=O)C=CC(C[C@@](O)([C@@H]6O)C)=C2C6=O
Structure Classification
Initial Source

Streptomyces sp.
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Room temperature in continental US; may vary elsewhere.
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Waldiomycin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Waldiomycin1342200-33-2AntibioticGram positive bacteriaWalk kinaseATP domainantibioticsInhibitorinhibitorinhibit

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