3-Acetyl-beta-boswellic acid

Cat. No.: HY-N2075 Purity: 98.10%: FAQs
Data Sheet SDS COA Handling Instructions

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3-Acetyl-beta-boswellic acid is a boswellic acid isolated from Boswellia serrata gum resin.

For research use only. We do not sell to patients.

3-Acetyl-beta-boswellic acid Chemical Structure

CAS No. : 5968-70-7

Size	Price	Stock	Quantity
1 mg	USD 45	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 140	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of 3-Acetyl-beta-boswellic acid:

3-Acetyl-beta-boswellic acid (Standard) Get quote

1 Publications Citing Use of MCE 3-Acetyl-beta-boswellic acid

•J Immunol. 2021 Mar 1;206(5):953-962. [Abstract]

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Biological Activity
Purity & Documentation
References
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Description

3-Acetyl-beta-boswellic acid is a boswellic acid isolated from Boswellia serrata gum resin^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	3 μM Compound: 3	Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured after 1 min by RP-HPLC analysis Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured after 1 min by RP-HPLC analysis	[PMID: 24844534]
HeLa	IC₅₀	22 μM Compound: 3, ABA	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 21334793]
HL-60	IC₅₀	10 μM Compound: 3, ABA	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 21334793]
HUVEC	IC₅₀	> 100 μM Compound: 2, ABA	Antiproliferation activity against HUVEC cells after 48 hrs by CCK-8 assay Antiproliferation activity against HUVEC cells after 48 hrs by CCK-8 assay	[PMID: 25819335]
Sf21	IC₅₀	> 40 μM Compound: 28	Inhibition of human recombinant COX2 expressed in baculovirus infected sf21 cells assessed as decrease in PGE2 formation using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition measured after 45 mins by LC-MS analysis Inhibition of human recombinant COX2 expressed in baculovirus infected sf21 cells assessed as decrease in PGE2 formation using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition measured after 45 mins by LC-MS analysis	[PMID: 31774676]

Molecular Weight

498.74

Formula

C₃₂H₅₀O₄

CAS No.

5968-70-7

Appearance

Solid

Color

White to off-white

SMILES

C[C@@]([C@@]12C)(CC[C@@]3([H])[C@@]4(C)C(O)=O)[C@@](CC=C1[C@@]([C@H]5C)([H])[C@](C)(CC[C@H]5C)CC2)([H])[C@]3(CC[C@H]4OC(C)=O)C

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (200.51 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0051 mL	10.0253 mL	20.0505 mL
5 mM	0.4010 mL	2.0051 mL	4.0101 mL
10 mM	0.2005 mL	1.0025 mL	2.0051 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.10%

Select Batch:

Data Sheet (274 KB) SDS (252 KB)

COA (252 KB) RP-HPLC (179 KB)

Handling Instructions (2659 KB)

References

[1]. Gerbeth K, et al. In vitro metabolism, permeation, and brain availability of six major boswellic acids from Boswellia serrata gum resins. Fitoterapia. 2013 Jan;84:99-106. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.0051 mL	10.0253 mL	20.0505 mL	50.1263 mL
	5 mM	0.4010 mL	2.0051 mL	4.0101 mL	10.0253 mL
	10 mM	0.2005 mL	1.0025 mL	2.0051 mL	5.0126 mL
	15 mM	0.1337 mL	0.6684 mL	1.3367 mL	3.3418 mL
	20 mM	0.1003 mL	0.5013 mL	1.0025 mL	2.5063 mL
	25 mM	0.0802 mL	0.4010 mL	0.8020 mL	2.0051 mL
	30 mM	0.0668 mL	0.3342 mL	0.6684 mL	1.6709 mL
	40 mM	0.0501 mL	0.2506 mL	0.5013 mL	1.2532 mL
	50 mM	0.0401 mL	0.2005 mL	0.4010 mL	1.0025 mL
	60 mM	0.0334 mL	0.1671 mL	0.3342 mL	0.8354 mL
	80 mM	0.0251 mL	0.1253 mL	0.2506 mL	0.6266 mL
	100 mM	0.0201 mL	0.1003 mL	0.2005 mL	0.5013 mL