Boc-Pip-butyn

Cat. No.: HY-147052: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Boc-Pip-butyn is an Alkyl/ether-based PROTAC linker. Boc-Pip-butyn is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

For research use only. We do not sell to patients.

Boc-Pip-butyn Chemical Structure

CAS No. : 1346153-07-8

Size	Price	Stock
5 mg	USD 100	Ask For Quote & Lead Time
10 mg	USD 160	Ask For Quote & Lead Time
25 mg	USD 320	Ask For Quote & Lead Time
50 mg	USD 510	Ask For Quote & Lead Time
100 mg	USD 820	Ask For Quote & Lead Time

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Biological Activity
Purity & Documentation
References
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Description

Boc-Pip-butyn is an Alkyl/ether-based PROTAC linker^[1]. Boc-Pip-butyn is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC₅₀ & Target^[1]

Alkyl/ether

Molecular Weight

237.34

Formula

C₁₄H₂₃NO₂

CAS No.

1346153-07-8

Appearance

Oil

Color

Colorless to light yellow

SMILES

O=C(N1CCC(CC1)CCC#C)OC(C)(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation

Purity: 95.79%

Select Batch:

Data Sheet (265 KB) SDS (251 KB)

COA (243 KB) HNMR (270 KB) RP-HPLC (283 KB) LCMS (89 KB)

Handling Instructions (2659 KB)

References

[1]. Yulu Zhou, et al. Photocatalytic Sulfonylcarbocyclization of Alkynes Using SEt as a Traceless Directing Group: Access to Cyclopentenes and Indenes. Angew Chem Int Ed Engl. 2022 Jan 3;61(1):e202110864. [Content Brief]

Boc-Pip-butyn Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Boc-Pip-butyn1346153-07-8PROTAC LinkersInhibitorinhibitorinhibit

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