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TAK-828F is a Potent, Selective and Orally Active RORγt Inverse Agonist

2019-04-25

TAK-828F is a potent, selective and orally active retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonist. TAK-828F inhibits IL-17A cytokine expression and reduces symptoms of autoimmune encephalomyelitis mice.

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