Search Result
Results for "
Caspase Substrate
" in MedChemExpress (MCE) Product Catalog:
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-P2091
-
|
Caspase
|
Inflammation/Immunology
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Ac-YVAD-pNA is a specific Caspase-1 substrate. Ac-YVAD-pNA can be used to detect Caspase-1 activity. Caspase-1 is a key mediator of inflammatory processes .
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-
- HY-P2617A
-
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Caspase
|
Inflammation/Immunology
Cancer
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Ac-WEHD-AFC TFA is a fluorogenic caspase-1 substrate. Ac-WEHD-AFC TFA can measure caspase-1 fluorogenic activity and can be used for the research of tumor and inflammation .
|
-
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- HY-P1169
-
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Caspase
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Others
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Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B .
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-
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- HY-P3363
-
|
Caspase
|
Cancer
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Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates .
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- HY-P10450
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D2R; (D)2-Rhodamine 110
|
Caspase
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Others
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(Asp)2-Rhodamine 110 (D2R) is a fluorescent caspase substrate .
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-
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- HY-P10083
-
-
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- HY-P2615
-
|
Fluorescent Dye
|
Cancer
|
Ac-VDVAD-AFC is a caspase-specific fluorescent substrate. Ac-VDVAD-AFC can measure caspase-3-like activity and caspase-2 activity and can be used for the research of tumor and cancer .
|
-
-
- HY-P2615A
-
|
Fluorescent Dye
|
Cancer
|
Ac-VDVAD-AFC TFA is a caspase-specific fluorescent substrate. Ac-VDVAD-AFC TFA can measure caspase-3-like activity and caspase-2 activity and can be used for the research of tumor and cancer .
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-
- HY-P4403
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(Z-Asp-Glu-Val-Asp)₂-Rhodamine 110
|
Fluorescent Dye
Apoptosis
Caspase
|
Others
|
Z-DEVD-R110 ((Z-Asp-Glu-Val-Asp)2-Rhodamine 110) is a fluorogenic caspase-3/7 substrate. Z-DEVD-R110 can be used to detect apoptosis. Z-DEVD-R110 is a rhodamine derivative with two four–amino acid (DEVD) peptides linked to the fuorophore .
|
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-
- HY-P2617
-
|
Caspase
|
Inflammation/Immunology
Cancer
|
Ac-WEHD-AFC is a fluorogenic caspase-1 substrate. Ac-WEHD-AFC can measure caspase-1 fluorogenic activity and can be used for the research of tumor and inflammation .
|
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- HY-P4392
-
-
-
- HY-P4401
-
|
Caspase
|
Others
|
Z-VEID-AFC is a fluorescent substrate for caspase-6 .
|
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-
- HY-P1093
-
|
Caspase
|
Others
|
Ac-LEHD-AFC is a fluorescent substrate for caspase-9, can be used to assess the activity of caspase .
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-
- HY-W713878
-
|
Caspase
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Others
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Ac-VDVAD-pNA is a caspase-2 substrate. Ac-VDVAD-pNA can be used to test the activity of caspase-2 .
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-
- HY-P10084
-
|
Caspase
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Others
|
Ac-VAD-pNA is a caspase-1 substrate. Ac-VAD-pNA can be used to detect caspase-1 activity .
|
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-
- HY-P10452
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|
Caspase
|
Others
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Ac-LEVDGWK(Dnp)-NH2 is a substrate for Caspase-3, and can be used to detect Caspase-3 activity .
|
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- HY-P5983
-
|
Caspase
|
Cancer
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Ac-VEID-AFC is a caspase-6 fluorogenic substrate, and can be used in the caspase 6 activity assay .
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- HY-P3475
-
|
Fluorescent Dye
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Others
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Mca-VDQMDGWK-(Dnp)-NH2 is a fluorogenic substrate for caspase-3 and can be used to quantify caspase-3 activity .
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-
- HY-P2614
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|
Caspase
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Others
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Mca-DEVDAP-K(Dnp)-OH is a fluorogenic substrate for caspase-3 .
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-
- HY-P1006
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|
Caspase
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Others
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Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) and related cysteine proteases.
|
-
-
- HY-P10276
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|
Caspase
|
Cancer
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Ac-VAD-AFC is a fluorescent substrate for caspases and can be used to test the activity of caspases .
|
-
-
- HY-P5974
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Z-Tyr-Val-Ala-Asp-pNA
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Caspase
|
Others
|
Z-YVAD-pNA (Z-Tyr-Val-Ala-Asp-pNA) is a caspase-1 substrate .
|
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-
- HY-P2208
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|
Fluorescent Dye
|
Cancer
|
Z-IETD-AFC, a specific fluorescence substrate, can be used to determine the caspase-8 catalytic activity .
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-
- HY-P3362
-
|
Fluorescent Dye
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Others
|
Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity .
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-
- HY-P3476
-
|
CRISPR/Cas9
|
Cancer
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Mca-VDQVDGW-Lys(Dnp)-NH2 is a fluorogenic substrate of caspase-7. Mca-VDQVDGW-K(Dnp)-NH2 can be used to quantify caspase-7 activity.
|
-
-
- HY-P10454
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(Z-Ile-Glu-Thr-Asp)2-R110
|
Caspase
|
Others
|
(Z-IETD)2-Rh 110 is a fluorescent substrate of caspase-8 (λex= 488 nm, λem= 523 nm), which can be used to detect the activity of caspase-8 and the process of apoptosis .
|
-
-
- HY-P4547
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AC-WEHD-AMC
|
Caspase
|
Others
|
Ac-Trp-Glu-His-Asp-AMC (AC-WEHD-AMC) is a potent fluorogenic substrate of caspase-1 .
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-
- HY-P10236
-
|
Caspase
|
Others
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Ac-WEHD-pNA is a colorimetric substrate for caspase 1, 4, 5 and 14, which is utilized to measure the caspase activity .
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- HY-D1652
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Caspase
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Others
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Ac-LEHD-AMC is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm). Caspase-9 can induce hydrolysis of Ac-LEHD-AMC, resulting in the release of AMC fluorophore and its fluorescence can be used to quantify caspase-9 activity .
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-
- HY-P2620
-
|
Fluorescent Dye
|
Metabolic Disease
Cancer
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Ac-LETD-AFC is a caspase-8 fluorogenic substrate. Ac-LETD-AFC can measure caspase-8 fluorogenic activity and can be used for the research of cancer cell apoptosis and oxidative stress metabolism .
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- HY-P10322
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Fluorescent Dye
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Cancer
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Z-IETD-R110 is a fluorescent substrate of caspases. Z-IETD-R110 acts as a substrate for caspase-8. When caspase-8 is activated, it can recognize and cut Z-IETD-R110, releasing fluorophore, which can be detected by fluorescence microscopy. Z-IETD-R110 can be used to study oxidative stress-induced apoptosis, particularly in pancreatic acinar cells .
|
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-
- HY-P2377
-
|
Fluorescent Dye
|
Others
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Ac-YVAD-AFC is the the fluorometric peptide substrate of caspase-1, with λ excitation of 400 nm and λ emission of 505 nm .
|
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-
- HY-P2616
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-
-
- HY-P10240
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-
-
- HY-P1986
-
|
Caspase
|
Cancer
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Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity .
|
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-
- HY-P2616A
-
-
-
- HY-P10001
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Z-Ile-Glu-Thr-Asp-pNA
|
Caspase
|
Cancer
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Z-IETD-pNA (Z-Ile-Glu-Thr-Asp-pNA) is a colorimetric caspase-8 and granzyme B substrate. Z-IETD-pNA is hydrlyzed by caspase 8 to generate pNA .
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- HY-120833
-
|
Caspase
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Others
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Ac-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8. Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity .
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- HY-P2065
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Fluorescent Dye
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Others
|
Ac-VEID-AMC is a fluorescent substrate for the determination of caspase-6 and related cysteine protease activities (Ex=340-360 nm, Em=440-460 nm) .
|
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-
- HY-P1003
-
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Fluorescent Dye
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Others
|
Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm .
|
-
-
- HY-P10142
-
|
Fluorescent Dye
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Others
|
Ac-YEVD-AMC is a fluorescent substrate of caspase-1/11. Ac-YEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection when treating with cell lysate .
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-
-
- HY-P10666
-
|
Caspase
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Others
|
Ac-VDQQD-pNA is a substrate of Caspase 2 and can be cleaved to produce yellow pNA (p-nitroaniline) .
|
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- HY-P2610
-
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Caspase
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Others
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Ac-VEID-pNA is an artificially synthesized peptide. Ac-VEID-pNA is utilized as substrate for caspase 6, that cleaves the lamin A at the cleavage site of VEID .
|
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-
- HY-124134
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LCL102
|
Ceramidase
Caspase
PARP
|
Cancer
|
AD-2646 (LCL102), a ceramide analog, can kill leukemic T cells (EC50: 40 μM). AD-2646 triggers the cleavage of caspase-8, -9 and -3, as well as the caspase substrate PARP. AD-2646 is a ceramidase inhibitor. AD-2646 induces an accumulation of endogenous ceramide owing to perturbed ceramide metabolism .
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-
- HY-P3110
-
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Fluorescent Dye
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Others
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Ac-WLA-AMC is a fluorogenic substrate of caspase-3. Ac-WLA-AMC is cleaved to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify the β5c subunit activity .
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- HY-P10082
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|
Caspase
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Others
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Ac-VETD-AMC is a synthetic peptide substrate for caspase 8. Ac-VETD-AMC also has potential to assess functional activity of recombinant phytaspase .
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- HY-P4400
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Fluorescent Dye
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Others
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Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals .
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- HY-P2016
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Proteasome
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Others
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Ac-Nle-Pro-Nle-Asp-AMC is a specific substrate for 26S proteasome. Ac-Nle-Pro-Nle-Asp-AMC can be used for the 26S proteasome caspase-like activity analysis .
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- HY-P2630
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Interleukin Related
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Inflammation/Immunology
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Suc-YVAD-pNA is a substrate of ICE. Interleukin-1β-converting enzyme (ICE) is a cysteine protease responsible for the cleavage of pre-interleukin-1β (pre-IL-1β) to the mature cytokine and a member of a family of related proteases (the caspases) .
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-
Cat. No. |
Product Name |
Type |
-
- HY-P1169
-
|
Fluorescent Dyes/Probes
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Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B .
|
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- HY-P3363
-
|
Chromogenic Substrates
|
Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates .
|
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- HY-P1093
-
|
Chromogenic Substrates
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Ac-LEHD-AFC is a fluorescent substrate for caspase-9, can be used to assess the activity of caspase .
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-
- HY-P2208
-
|
Fluorescent Dyes/Probes
|
Z-IETD-AFC, a specific fluorescence substrate, can be used to determine the caspase-8 catalytic activity .
|
-
- HY-P2377
-
|
Dyes
|
Ac-YVAD-AFC is the the fluorometric peptide substrate of caspase-1, with λ excitation of 400 nm and λ emission of 505 nm .
|
-
- HY-P3475
-
|
Fluorescent Dyes/Probes
|
Mca-VDQMDGWK-(Dnp)-NH2 is a fluorogenic substrate for caspase-3 and can be used to quantify caspase-3 activity .
|
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- HY-P2614
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-
- HY-W338079
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-
- HY-P3362
-
|
Fluorescent Dyes/Probes
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Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity .
|
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- HY-P2616
-
|
Chromogenic Substrates
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Mca-YVADAP-Lys(Dnp)-OH is a fluorogenic substrate for caspase-1 and angiotensin-converting enzyme 2 (ACE2) .
|
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- HY-P1986
-
|
Fluorescent Dyes/Probes
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Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity .
|
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- HY-P2065
-
|
Fluorescent Dyes/Probes
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Ac-VEID-AMC is a fluorescent substrate for the determination of caspase-6 and related cysteine protease activities (Ex=340-360 nm, Em=440-460 nm) .
|
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- HY-P1003
-
|
Chromogenic Substrates
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Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm .
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- HY-P3110
-
|
Dyes
|
Ac-WLA-AMC is a fluorogenic substrate of caspase-3. Ac-WLA-AMC is cleaved to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify the β5c subunit activity .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P2091
-
|
Caspase
|
Inflammation/Immunology
|
Ac-YVAD-pNA is a specific Caspase-1 substrate. Ac-YVAD-pNA can be used to detect Caspase-1 activity. Caspase-1 is a key mediator of inflammatory processes .
|
-
- HY-P2617A
-
|
Caspase
|
Inflammation/Immunology
Cancer
|
Ac-WEHD-AFC TFA is a fluorogenic caspase-1 substrate. Ac-WEHD-AFC TFA can measure caspase-1 fluorogenic activity and can be used for the research of tumor and inflammation .
|
-
- HY-P1169
-
|
Caspase
|
Others
|
Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B .
|
-
- HY-P10145
-
|
Peptides
|
Others
|
Ac-LEVD-pNA is a chromogenic substrate for caspase-4 and can be used to detect caspase-4 activity .
|
-
- HY-P10450
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D2R; (D)2-Rhodamine 110
|
Caspase
|
Others
|
(Asp)2-Rhodamine 110 (D2R) is a fluorescent caspase substrate .
|
-
- HY-P10083
-
-
- HY-P2615
-
|
Fluorescent Dye
|
Cancer
|
Ac-VDVAD-AFC is a caspase-specific fluorescent substrate. Ac-VDVAD-AFC can measure caspase-3-like activity and caspase-2 activity and can be used for the research of tumor and cancer .
|
-
- HY-P2615A
-
|
Fluorescent Dye
|
Cancer
|
Ac-VDVAD-AFC TFA is a caspase-specific fluorescent substrate. Ac-VDVAD-AFC TFA can measure caspase-3-like activity and caspase-2 activity and can be used for the research of tumor and cancer .
|
-
- HY-P4403
-
(Z-Asp-Glu-Val-Asp)₂-Rhodamine 110
|
Fluorescent Dye
Apoptosis
Caspase
|
Others
|
Z-DEVD-R110 ((Z-Asp-Glu-Val-Asp)2-Rhodamine 110) is a fluorogenic caspase-3/7 substrate. Z-DEVD-R110 can be used to detect apoptosis. Z-DEVD-R110 is a rhodamine derivative with two four–amino acid (DEVD) peptides linked to the fuorophore .
|
-
- HY-P2617
-
|
Caspase
|
Inflammation/Immunology
Cancer
|
Ac-WEHD-AFC is a fluorogenic caspase-1 substrate. Ac-WEHD-AFC can measure caspase-1 fluorogenic activity and can be used for the research of tumor and inflammation .
|
-
- HY-P3363
-
|
Caspase
|
Cancer
|
Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates .
|
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- HY-P4392
-
-
- HY-P4401
-
|
Caspase
|
Others
|
Z-VEID-AFC is a fluorescent substrate for caspase-6 .
|
-
- HY-P4429
-
|
Peptides
|
Others
|
Z-YVAD-AFC is a fluorescent substrate for Caspase-1, which can be used to detect and measure the activity of Caspase-1 .
|
-
- HY-W713878
-
|
Caspase
|
Others
|
Ac-VDVAD-pNA is a caspase-2 substrate. Ac-VDVAD-pNA can be used to test the activity of caspase-2 .
|
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- HY-P10084
-
|
Caspase
|
Others
|
Ac-VAD-pNA is a caspase-1 substrate. Ac-VAD-pNA can be used to detect caspase-1 activity .
|
-
- HY-P10452
-
|
Caspase
|
Others
|
Ac-LEVDGWK(Dnp)-NH2 is a substrate for Caspase-3, and can be used to detect Caspase-3 activity .
|
-
- HY-P5983
-
|
Caspase
|
Cancer
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Ac-VEID-AFC is a caspase-6 fluorogenic substrate, and can be used in the caspase 6 activity assay .
|
-
- HY-P5348
-
|
Peptides
|
Others
|
Ac-LEHD-pNA is a biological active peptide. (Caspase-9 substrate; pNA (4-nitroaniline)-derived caspase substrates are widely used for the colorimetric detection of various caspase activities. Cleavage of pNA peptides by caspases generates pNA that is monitored colorimetrically at ~405 nm. pNA has maximum absorption around 408 nm.)
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-
- HY-P3475
-
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Fluorescent Dye
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Others
|
Mca-VDQMDGWK-(Dnp)-NH2 is a fluorogenic substrate for caspase-3 and can be used to quantify caspase-3 activity .
|
-
- HY-P2614
-
|
Caspase
|
Others
|
Mca-DEVDAP-K(Dnp)-OH is a fluorogenic substrate for caspase-3 .
|
-
- HY-P1006
-
|
Caspase
|
Others
|
Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) and related cysteine proteases.
|
-
- HY-P10276
-
|
Caspase
|
Cancer
|
Ac-VAD-AFC is a fluorescent substrate for caspases and can be used to test the activity of caspases .
|
-
- HY-P5974
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Z-Tyr-Val-Ala-Asp-pNA
|
Caspase
|
Others
|
Z-YVAD-pNA (Z-Tyr-Val-Ala-Asp-pNA) is a caspase-1 substrate .
|
-
- HY-P2208
-
|
Fluorescent Dye
|
Cancer
|
Z-IETD-AFC, a specific fluorescence substrate, can be used to determine the caspase-8 catalytic activity .
|
-
- HY-P3362
-
|
Fluorescent Dye
|
Others
|
Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity .
|
-
- HY-P3476
-
|
CRISPR/Cas9
|
Cancer
|
Mca-VDQVDGW-Lys(Dnp)-NH2 is a fluorogenic substrate of caspase-7. Mca-VDQVDGW-K(Dnp)-NH2 can be used to quantify caspase-7 activity.
|
-
- HY-P10454
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(Z-Ile-Glu-Thr-Asp)2-R110
|
Caspase
|
Others
|
(Z-IETD)2-Rh 110 is a fluorescent substrate of caspase-8 (λex= 488 nm, λem= 523 nm), which can be used to detect the activity of caspase-8 and the process of apoptosis .
|
-
- HY-P4547
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AC-WEHD-AMC
|
Caspase
|
Others
|
Ac-Trp-Glu-His-Asp-AMC (AC-WEHD-AMC) is a potent fluorogenic substrate of caspase-1 .
|
-
- HY-P10236
-
|
Caspase
|
Others
|
Ac-WEHD-pNA is a colorimetric substrate for caspase 1, 4, 5 and 14, which is utilized to measure the caspase activity .
|
-
- HY-P2620
-
|
Fluorescent Dye
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Metabolic Disease
Cancer
|
Ac-LETD-AFC is a caspase-8 fluorogenic substrate. Ac-LETD-AFC can measure caspase-8 fluorogenic activity and can be used for the research of cancer cell apoptosis and oxidative stress metabolism .
|
-
- HY-P10322
-
|
Fluorescent Dye
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Cancer
|
Z-IETD-R110 is a fluorescent substrate of caspases. Z-IETD-R110 acts as a substrate for caspase-8. When caspase-8 is activated, it can recognize and cut Z-IETD-R110, releasing fluorophore, which can be detected by fluorescence microscopy. Z-IETD-R110 can be used to study oxidative stress-induced apoptosis, particularly in pancreatic acinar cells .
|
-
- HY-P2377
-
|
Fluorescent Dye
|
Others
|
Ac-YVAD-AFC is the the fluorometric peptide substrate of caspase-1, with λ excitation of 400 nm and λ emission of 505 nm .
|
-
- HY-P2616
-
-
- HY-P3115
-
|
Peptides
|
Others
|
Ac-LEVD-AFC is capspase-4 fluorogenic substrate peptide that can be used for caspase-4 activity studies .
|
-
- HY-P10240
-
-
- HY-P1986
-
|
Caspase
|
Cancer
|
Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity .
|
-
- HY-P2616A
-
-
- HY-P10001
-
Z-Ile-Glu-Thr-Asp-pNA
|
Caspase
|
Cancer
|
Z-IETD-pNA (Z-Ile-Glu-Thr-Asp-pNA) is a colorimetric caspase-8 and granzyme B substrate. Z-IETD-pNA is hydrlyzed by caspase 8 to generate pNA .
|
-
- HY-120833
-
|
Caspase
|
Others
|
Ac-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8. Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity .
|
-
- HY-P2065
-
|
Fluorescent Dye
|
Others
|
Ac-VEID-AMC is a fluorescent substrate for the determination of caspase-6 and related cysteine protease activities (Ex=340-360 nm, Em=440-460 nm) .
|
-
- HY-P1003
-
|
Fluorescent Dye
|
Others
|
Ac-DEVD-AMC is a fluorescent substrate of caspase-3/caspase-7. When treating Ac-DEVD-AMC with cell lysate, Ac-DEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection, with an excitation wavelength of 380 nm and an emission wavelength of 460 nm .
|
-
- HY-P10142
-
|
Fluorescent Dye
|
Others
|
Ac-YEVD-AMC is a fluorescent substrate of caspase-1/11. Ac-YEVD-AMC releases amino-4-methylcoumarin (AMC) for fluorescence detection when treating with cell lysate .
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- HY-P10666
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Caspase
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Others
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Ac-VDQQD-pNA is a substrate of Caspase 2 and can be cleaved to produce yellow pNA (p-nitroaniline) .
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- HY-P2610
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Caspase
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Others
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Ac-VEID-pNA is an artificially synthesized peptide. Ac-VEID-pNA is utilized as substrate for caspase 6, that cleaves the lamin A at the cleavage site of VEID .
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- HY-P3110
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Fluorescent Dye
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Others
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Ac-WLA-AMC is a fluorogenic substrate of caspase-3. Ac-WLA-AMC is cleaved to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify the β5c subunit activity .
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- HY-P10082
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Caspase
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Others
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Ac-VETD-AMC is a synthetic peptide substrate for caspase 8. Ac-VETD-AMC also has potential to assess functional activity of recombinant phytaspase .
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- HY-P10244F
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Peptides
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Infection
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Biotin-YVAD-FMK is an inhibitor for vacuolar processing enzyme (VPE), with a 64% inhibition at 5 μM. Biotin-YVAD-FMK is an irreversible substrate for caspase 1 .
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- HY-P4400
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Fluorescent Dye
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Others
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Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals .
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- HY-P10161
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Peptides
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Others
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Ac-DMQD-pNA is a peptide substrate. Both of the recombinant CgCaspase-1 (rCgCaspase-1) and the C-terminus of CgCaspase-1 (rCgCaspase-1-C) exhibits similar caspase activity towards proteolytic substrate Ac-DMQD-pNA and Ac-DEVD-pNA (HY-P1006) .
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- HY-P2016
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Proteasome
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Others
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Ac-Nle-Pro-Nle-Asp-AMC is a specific substrate for 26S proteasome. Ac-Nle-Pro-Nle-Asp-AMC can be used for the 26S proteasome caspase-like activity analysis .
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- HY-P2630
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Interleukin Related
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Inflammation/Immunology
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Suc-YVAD-pNA is a substrate of ICE. Interleukin-1β-converting enzyme (ICE) is a cysteine protease responsible for the cleavage of pre-interleukin-1β (pre-IL-1β) to the mature cytokine and a member of a family of related proteases (the caspases) .
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- HY-K1088
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MCE VF 488 Caspase 3 Assay Kit for Live Cells uses a fluorescent substrate with cell membrane permeability to detect Caspase 3 activity in live cells.
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