2. Metabolic Enzyme/Protease
  3. Proteasome
  4. Ac-Nle-Pro-Nle-Asp-AMC

Ac-Nle-Pro-Nle-Asp-AMC is a specific substrate for 26S proteasome. Ac-Nle-Pro-Nle-Asp-AMC can be used for the 26S proteasome caspase-like activity analysis.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Ac-Nle-Pro-Nle-Asp-AMC Chemical Structure

Ac-Nle-Pro-Nle-Asp-AMC Chemical Structure

CAS No. : 355140-49-7

Size Price Stock Quantity
1 mg USD 220 In-stock
5 mg USD 820 In-stock
10 mg USD 1320 In-stock
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100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Ac-Nle-Pro-Nle-Asp-AMC Related Antibodies

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Description

Ac-Nle-Pro-Nle-Asp-AMC is a specific substrate for 26S proteasome. Ac-Nle-Pro-Nle-Asp-AMC can be used for the 26S proteasome caspase-like activity analysis[1][2][3].

Molecular Weight

655.74

Formula

C33H45N5O9
CAS No.
Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (152.50 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5250 mL 7.6250 mL 15.2499 mL
5 mM 0.3050 mL 1.5250 mL 3.0500 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5250 mL 7.6250 mL 15.2499 mL 38.1249 mL
5 mM 0.3050 mL 1.5250 mL 3.0500 mL 7.6250 mL
10 mM 0.1525 mL 0.7625 mL 1.5250 mL 3.8125 mL
15 mM 0.1017 mL 0.5083 mL 1.0167 mL 2.5417 mL
20 mM 0.0762 mL 0.3812 mL 0.7625 mL 1.9062 mL
25 mM 0.0610 mL 0.3050 mL 0.6100 mL 1.5250 mL
30 mM 0.0508 mL 0.2542 mL 0.5083 mL 1.2708 mL
40 mM 0.0381 mL 0.1906 mL 0.3812 mL 0.9531 mL
50 mM 0.0305 mL 0.1525 mL 0.3050 mL 0.7625 mL
60 mM 0.0254 mL 0.1271 mL 0.2542 mL 0.6354 mL
80 mM 0.0191 mL 0.0953 mL 0.1906 mL 0.4766 mL
100 mM 0.0152 mL 0.0762 mL 0.1525 mL 0.3812 mL
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Ac-Nle-Pro-Nle-Asp-AMC Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ac-Nle-Pro-Nle-Asp-AMC355140-49-7Proteasomespecific substrate26S proteasomecaspase-like activityInhibitorinhibitorinhibit

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