2. Neuronal Signaling Apoptosis
  3. Cholinesterase (ChE) Caspase
  4. Mca-YVADAP-Lys(Dnp)-OH TFA

Mca-YVADAP-Lys(Dnp)-OH TFA is a fluorogenic substrate for caspase-1 and angiotensin-converting enzyme 2 (ACE2).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Mca-YVADAP-Lys(Dnp)-OH TFA Chemical Structure

Mca-YVADAP-Lys(Dnp)-OH TFA Chemical Structure

Size Price Stock Quantity
1 mg USD 220 In-stock
5 mg USD 550 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Mca-YVADAP-Lys(Dnp)-OH TFA:

Mca-YVADAP-Lys(Dnp)-OH TFA Related Antibodies

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Caspase 1 Caspase 2 Caspase 3 Caspase 4 Caspase 5 Caspase 6 Caspase 7 Caspase 8 Caspase 9 Caspase 10 Caspase 12 Caspase Caspase 11 Caspase-13

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Mca-YVADAP-Lys(Dnp)-OH TFA is a fluorogenic substrate for caspase-1 and angiotensin-converting enzyme 2 (ACE2)[1].

IC50 & Target[1]

Caspase-1

 

AChE

 

Molecular Weight

1259.15

Formula

C55H65F3N10O21
Appearance

Solid

Color

White to yellow

Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 22.22 mg/mL (17.65 mM; ultrasonic and adjust pH to 9 with 1M NaOH)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7942 mL 3.9709 mL 7.9419 mL
5 mM 0.1588 mL 0.7942 mL 1.5884 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 98.85%

COA (250 KB) LCMS (94 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.7942 mL 3.9709 mL 7.9419 mL 19.8547 mL
5 mM 0.1588 mL 0.7942 mL 1.5884 mL 3.9709 mL
10 mM 0.0794 mL 0.3971 mL 0.7942 mL 1.9855 mL
15 mM 0.0529 mL 0.2647 mL 0.5295 mL 1.3236 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mca-YVADAP-Lys(Dnp)-OH TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mca-YVADAP-Lys(Dnp)-OHCholinesterase (ChE)CaspaseInhibitorinhibitorinhibit

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