2. Apoptosis
  3. Caspase
  4. Ac-Trp-Glu-His-Asp-AMC

Ac-Trp-Glu-His-Asp-AMC  (Synonyms: AC-WEHD-AMC)

Cat. No.: HY-P4547 Purity: 99.84%
SDS
COA
Handling Instructions Technical Support

Ac-Trp-Glu-His-Asp-AMC (AC-WEHD-AMC) is a potent fluorogenic substrate of caspase-1.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Ac-Trp-Glu-His-Asp-AMC Chemical Structure

Ac-Trp-Glu-His-Asp-AMC Chemical Structure

CAS No. : 189275-74-9

Size Price Stock Quantity
1 mg In-stock
5 mg In-stock
10 mg In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Ac-Trp-Glu-His-Asp-AMC Related Antibodies

Top Publications Citing Use of Products

View All Caspase Isoform Specific Products:

View All Isoforms
Caspase 1 Caspase 2 Caspase 3 Caspase 4 Caspase 5 Caspase 6 Caspase 7 Caspase 8 Caspase 9 Caspase 10 Caspase 12 Caspase Caspase 11 Caspase-13

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Ac-Trp-Glu-His-Asp-AMC (AC-WEHD-AMC) is a potent fluorogenic substrate of caspase-1[1].

Molecular Weight

784.77

Formula

C38H40N8O11
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Ac-Trp-Glu-His-{Asp-AMC}
Sequence Shortening

Ac-WEH-{Asp-AMC}
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (127.43 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2743 mL 6.3713 mL 12.7426 mL
5 mM 0.2549 mL 1.2743 mL 2.5485 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.2743 mL 6.3713 mL 12.7426 mL 31.8565 mL
5 mM 0.2549 mL 1.2743 mL 2.5485 mL 6.3713 mL
10 mM 0.1274 mL 0.6371 mL 1.2743 mL 3.1856 mL
15 mM 0.0850 mL 0.4248 mL 0.8495 mL 2.1238 mL
20 mM 0.0637 mL 0.3186 mL 0.6371 mL 1.5928 mL
25 mM 0.0510 mL 0.2549 mL 0.5097 mL 1.2743 mL
30 mM 0.0425 mL 0.2124 mL 0.4248 mL 1.0619 mL
40 mM 0.0319 mL 0.1593 mL 0.3186 mL 0.7964 mL
50 mM 0.0255 mL 0.1274 mL 0.2549 mL 0.6371 mL
60 mM 0.0212 mL 0.1062 mL 0.2124 mL 0.5309 mL
80 mM 0.0159 mL 0.0796 mL 0.1593 mL 0.3982 mL
100 mM 0.0127 mL 0.0637 mL 0.1274 mL 0.3186 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Ac-Trp-Glu-His-Asp-AMC Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ac-Trp-Glu-His-Asp-AMC189275-74-9AC-WEHD-AMCCaspaseInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Ac-Trp-Glu-His-Asp-AMC
Cat. No.:
HY-P4547
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

English - EN (252 KB) Français - FR (252 KB) Deutsch - DE (252 KB) Norwegian - NO (252 KB) Español - ES (252 KB) Swedish - SV (252 KB)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.