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Chromophore

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) Apoptosis (1) Bacterial (1) Endogenous Metabolite (3) Fluorescent Dye (11) IFNAR (1) Isotope-Labeled Compounds (1)
By Research Areas:	Cancer (1) Infection (1) Metabolic Disease (2) Neurological Disease (2)
Oligonucleotides:	Aptamers (1)

Inhibitors & Agonists

Fluorescent Dye

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-147170

(1,1'-Dipyrenyl)dimethyl ether	Fluorescent Dye	Others
(1,1'-Dipyrenyl)dimethyl ether exhibits intramolecular excimer fluorescence in competition with fluorescence from the locally excited pyrene chromophore. (1,1'-Dipyrenyl)dimethyl ether is soluble in synthetic phospholipid membranes .

HY-W008292

Carbostyril 124	Fluorescent Dye	Others
Carbostyril 124 is a sensitising chromophore. Carbostyril 124 is a reasonably effective organic sensitizer for a proximate bound terbium ion .

HY-161159

DMHBO+	Fluorescent Dye	Others
DMHBO+ is a cationic chromophore that binds to the Chili aptamer with a K_d of 12 nM. The Chili-DMHBO+ complex is an ideal fluorescence donor for FRET to the rhodamine dye Atto 590, suitable for imaging RNA in cells. Ex/Em=456/592 nm .

HY-14264

Cyamemazine	5-HT Receptor	Neurological Disease
Cyamemazine is a neuroleptic agent that contains the phenothiazine chromophore. Cyamemazine is often used as an anxiolytic. Cyamemazine is a potent 5-HT₃ (K_i of 12 nM), 5-HT_2A (K_i = 1.5 nM) and 5-HT_2C (K_i of 75 nM) receptors antagonist with antipsychotic activity .

HY-135235

Cysteine thiol probe	Fluorescent Dye	Others
Cysteine Thiol Probe is a thiol-based probe designed to label electrophilic natural products. Cysteine Thiol Probe possesses each of the characteristics of an ideal pharmacophore probe, and has a chromophore. Cysteine Thiol Probe is capable of engaging enone-, β-lactam-, and β-lactone-based electrophilic metabolites .

HY-W247130

6-Methoxy-N-ethylquinoliniumiodide	Others	Others
6-Methoxy-N-ethylquinoliniumiodide is a chloride-specific chromophore .

HY-D1045A

Dabcyl acid sodium DABCYL sodium; Para-methyl red sodium	Fluorescent Dye	Others
Dabcyl acid sodium (DABCYL sodium) is a nonfluorescent chromophore and a quencher. Dabcyl acid sodium can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions .

HY-139976

1-SG	Others	Others
1-SG is an organogelator that consists of a solvatofluorochromic green fluorescence protein (GFP) chromophore and a sugar gelator (SG) .

HY-20794

8-Hydroxyjulolidine	Fluorescent Dye	Others
8-Hydroxyjulolidine is a chromophore moiety of a fluorescent probe for the detection of weak acid ions. 8-Hydroxyjulolidine can be used to synthesize the salicylaldehyde derivative 9-formyl-8-hydroxyjulolidine, which exhibits sensitive detection ability to pH changes of hydrogen sulfide and silicate in aqueous solution .

HY-116711

11-cis-Retinal	Endogenous Metabolite	Others
11-cis-Retinal is a chromophore linkes via a Schiff base to the lysine residue of opsin .

HY-136497

Coenzyme FO	Bacterial Endogenous Metabolite	Metabolic Disease
Coenzyme FO, a deazaflavin chromophore, acts as an important hydride acceptor/donor in the central methanogenic pathway .

HY-136884

DAR-4M	Fluorescent Dye	Others
DAR-4M is a fluorescent indicator for nitric oxide (NO) based on the rhodamine chromophore (Ex/Em= 550/572 nm) .

HY-110250

DFHBI Maximum Cited Publications 7 Publications Verification	Fluorescent Dye	Others
DFHBI is a small molecule that resembles the chromophore of green fluorescent protein (GFP). Spinach and DFHBI are essentially nonfluorescent when unbound, whereas the Spinach-DFHBI complex is brightly fluorescent both in vitro and in living cells.

HY-D0988

R-PE (R-Phycoerythrin)	Fluorescent Dye	Others
R-Phycoerythrin is a phycobiliproteins could be isolated from Heterosiphonia japonica. R-Phycoerythrin is a potent fluorescent probe contains four chromophore-carrying subunits that exhibits extremely bright red-orange fluorescence. (λex=496 nm, λem=578 nm) .

HY-147124

RIG012	IFNAR	Infection Cancer
RIG012 is a potent RIG-I inhibitor with an IC₅₀ of 0.71 μM using the NADH-coupled ATPase assay. RIG012 inhibits IFN-β and ISG hRsad2 expression .

HY-D1815

Allophycocyanin 1 Publications Verification APC Dye	Fluorescent Dye	Others
Allophycocyanin (APC Dye) is a light-harvesting protein, containing strongly coupled dimers of chromophores. Allophycocyanin serve as a minimal system to examine photosynthetic energy transfer. Allophycocyanin strongly absorbs far-red light (FRL), and expresses during acclimation to low light, likely associates with chlorophyll a-containing photosystem I .

HY-W004500

All-trans-retinal 1 Publications Verification	Endogenous Metabolite Apoptosis	Metabolic Disease
All-trans-retinal is an vitamin A metabolite in the retina, and is produced following photo-isomerization of the visual chromophore 11-cis-Retinal. All-trans-retinal is cleared from photoreceptors by ATP-binding cassette transporter (ABCA4) and all-trans-retinol dehydrogenase (RDH). All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis .

HY-14264S

Cyamemazine-d6	Isotope-Labeled Compounds 5-HT Receptor	Neurological Disease
Cyamemazine-d₆ is the deuterium labeled Cyamemazine. Cyamemazine is a neuroleptic agent that contains the phenothiazine chromophore. Cyamemazine is often used as an anxiolytic. Cyamemazine is a potent 5-HT3 (Ki of 12 nM), 5-HT2A (Ki = 1.5 nM) and 5-HT2C (Ki of 75 nM) receptors antagonist with antipsychotic activity[1][2].

HY-W089353

8-Phenyl-BODIPY 505/515	Fluorescent Dye	Others
8-Phenyl-BODIPY 505/515, a phenyl-substituted BODIPY derivative, is a fluorophore, 8-Phenyl-BODIPY 505/515 can be used as fluorescent probe .

HY-121690

Semotiadil SD-3211	Others	Others
Semotiadil is a novel calcium antagonist whose stereochemical structure was investigated by X-ray crystallography and circular dichroism spectroscopy. X-ray structural analysis was performed using its enantiomeric salts with (S)-(+)-mandelic acid (2); 1 (mandelate salt). The R absolute configuration of 1, which was previously determined by chemical transformation of an optically active synthetic precursor, was directly confirmed by this analysis. Hydrogen bonding, charge repulsion, and hydrophobic interactions that stabilize the crystal structure were observed in the crystals. Circular dichroism spectra of 1 (mandelate salt) and 1 (hydrofuranate salt) in ethanolic solution showed similar spectral patterns. The CD bands of each chromophore were unambiguously assigned, and the conformation of the benzothiazole ring was determined using the optical rotation rule. The X-ray and CD data confirmed the P conformation of the benzothiazole ring and the equatorial position of the 2-phenyl ring in both the crystal and ethanolic solution states. These findings are in good agreement with our previous results on the conformational analysis of 2-arylbenzothiazole derivatives.

Cat. No.	Product Name	Type

HY-147170

(1,1'-Dipyrenyl)dimethyl ether	Fluorescent Dyes/Probes
(1,1'-Dipyrenyl)dimethyl ether exhibits intramolecular excimer fluorescence in competition with fluorescence from the locally excited pyrene chromophore. (1,1'-Dipyrenyl)dimethyl ether is soluble in synthetic phospholipid membranes .

HY-W008292

Carbostyril 124	Fluorescent Dyes/Probes
Carbostyril 124 is a sensitising chromophore. Carbostyril 124 is a reasonably effective organic sensitizer for a proximate bound terbium ion .

HY-110250

DFHBI 5+ Cited Publications	Fluorescent Dyes/Probes
DFHBI is a small molecule that resembles the chromophore of green fluorescent protein (GFP). Spinach and DFHBI are essentially nonfluorescent when unbound, whereas the Spinach-DFHBI complex is brightly fluorescent both in vitro and in living cells.

HY-D0988

R-PE (R-Phycoerythrin)	Dyes
R-Phycoerythrin is a phycobiliproteins could be isolated from Heterosiphonia japonica. R-Phycoerythrin is a potent fluorescent probe contains four chromophore-carrying subunits that exhibits extremely bright red-orange fluorescence. (λex=496 nm, λem=578 nm) .

HY-D1815

Allophycocyanin 1 Publications Verification APC Dye	Dyes
Allophycocyanin (APC Dye) is a light-harvesting protein, containing strongly coupled dimers of chromophores. Allophycocyanin serve as a minimal system to examine photosynthetic energy transfer. Allophycocyanin strongly absorbs far-red light (FRL), and expresses during acclimation to low light, likely associates with chlorophyll a-containing photosystem I .

HY-W089353

8-Phenyl-BODIPY 505/515	Fluorescent Dyes/Probes
8-Phenyl-BODIPY 505/515, a phenyl-substituted BODIPY derivative, is a fluorophore, 8-Phenyl-BODIPY 505/515 can be used as fluorescent probe .

HY-D1045A

Dabcyl acid sodium DABCYL sodium; Para-methyl red sodium	Fluorescent Dyes/Probes
Dabcyl acid sodium (DABCYL sodium) is a nonfluorescent chromophore and a quencher. Dabcyl acid sodium can be used as molecular beacon nucleic acid probes to recognize and report the presence of specific nucleic acids in homogeneous solutions .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-136497

Coenzyme FO	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Bacterial Endogenous Metabolite
Coenzyme FO, a deazaflavin chromophore, acts as an important hydride acceptor/donor in the central methanogenic pathway .

HY-W004500

All-trans-retinal 1 Publications Verification	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Terpenoids Source classification Other Diseases Diterpenoids Endogenous metabolite Disease Research Fields	Endogenous Metabolite Apoptosis
All-trans-retinal is an vitamin A metabolite in the retina, and is produced following photo-isomerization of the visual chromophore 11-cis-Retinal. All-trans-retinal is cleared from photoreceptors by ATP-binding cassette transporter (ABCA4) and all-trans-retinol dehydrogenase (RDH). All-trans-retinal induces Bax activation via DNA damage to mediate retinal cell apoptosis .

HY-116711

11-cis-Retinal	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
11-cis-Retinal is a chromophore linkes via a Schiff base to the lysine residue of opsin .

Cat. No.	Product Name	Chemical Structure

HY-14264S

Cyamemazine-d6
Cyamemazine-d₆ is the deuterium labeled Cyamemazine. Cyamemazine is a neuroleptic agent that contains the phenothiazine chromophore. Cyamemazine is often used as an anxiolytic. Cyamemazine is a potent 5-HT3 (Ki of 12 nM), 5-HT2A (Ki = 1.5 nM) and 5-HT2C (Ki of 75 nM) receptors antagonist with antipsychotic activity[1][2].

Cat. No.	Product Name		Classification

HY-153843

RNA Aptamer Corn sodium		Aptamers
RNA Aptamer Corn (sodium) is a 28-nt-long aptamer that is substantially shorter than Spinach and Spinach2 and exhibits bright red fluorescence upon binding DFHO (a soluble analog of the intrinsic fluorophore of red fluorescent protein), RNA Aptamer Corn (sodium) can be used to visualize RNA expression or localization in live cells which have been soaked with chromophores. The Corn-DFHO does not become appreciably cytotoxic when illuminated. And most importantly, Corn-DFHO exhibits markedly increased photostability compared to other aptamer-chromophore complexes both in vitro and in vivo. (36 nt Corn construct: 5'-GGCGCGAGGAAGGAGGUCUGAGGAGGUCACUGCGCC-3'; A 36-nt RNA construct, comprised of the 28-nt minimal Corn sequence extended proximally with a 4 base-pair stem.)

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Chromophore

Inhibitors & Agonists

Fluorescent Dye

NaturalProducts

Isotope-Labeled Compounds

Oligonucleotides

Natural
Products