Lewis X

By Targets:	Biochemical Assay Reagents (3) Endogenous Metabolite (4) FAK (1) Parasite (1) Sialyltransferase (1)
By Research Areas:	Cancer (3) Infection (2) Inflammation/Immunology (2) Metabolic Disease (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W020790

*Sialyl-Lewis* X** sLeX	Endogenous Metabolite	Inflammation/Immunology
Sialyl-Lewis X (sLeX) is a sialylated fucosylated tetrasaccharide, an endogenous antigen. Sialyl-Lewis X is a high-affinity ligand for selectins (E-, P-, and L-selectin) . Sialyl-Lewis X binds to ELAM-1 and CD62 and has the ability?to inhibits CD62-mediated neutrophil recruitment to sites of inflammation .

HY-N10535

Lewis y tetrasaccharide Lewis y	FAK	Cancer
Lewis Y tetrasaccharide (Lewis Y, Le ^Y) is a tetrasaccharide derivative form of Lewis X trisaccharide (HY-N10534). Lewis Y tetrasaccharide is an antigen associated with malignant ovarian carcinomas metastasis and poor prognosis .

HY-110288

3FAx-Neu5Ac	Sialyltransferase	Metabolic Disease
3FAx-Neu5Ac (compound 8), a Sialic acid peracetylated analog, is a sialyltransferase inhibitor. 3FAx-Neu5Ac substantially reduces expression of the sialylated ligand sialyl Lewis X on myeloid cells .

HY-126854

N-Acetyllactosamine N-Acetyl-D-lactosamine	Endogenous Metabolite	Others
N-Acetyllactosamine (LacNAc), a nitrogen-containing disaccharide, is an important component of various oligosaccharides such as glycoproteins and sialyl Lewis X. N-Acetyllactosamine can be used as the starting material for the synthesis of various oligosaccharides. N-Acetyllactosamine has prebiotic effects .

HY-N10534

Lewis X trisaccharide Lewis X	Parasite	Infection Inflammation/Immunology Cancer
Lewis X trisaccharide (Lewis X, Le ^x) is a potent T_H2 regulator, antagonizes LPS-induced IL-12 immune expression. Lewis X trisaccharide is a human histo-blood group antigen, plays an key role in cell-cell adhesion, and servers as a tumor marker. Lewis X trisaccharide is highly expressed in the outer membrane of the parasite, can be used for the immunology research of schistosomiasis .

HY-N12918

Lewis X tetrasaccharide	Others	Infection
Lewis X tetrasaccharide is a cell surface glycan that can be used for diagnosis of microbial infections.

HY-W698344

Lewis X Trisaccharide,Methyl Glycoside	Biochemical Assay Reagents	Others
Lewis X Trisaccharide,Methyl Glycoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-W145535

*Sialyl lewis* x-lactose**	Biochemical Assay Reagents Endogenous Metabolite	Others
Sialyl Lewis X-Lactose is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-E70303

Fucosyltransferase 6 FUT6	Endogenous Metabolite	Cancer
Fucosyltransferase 6 is a fucosyltransferase that mediates the expression of the tetrasaccharide Sialyl-Lewis x (sLex, CD15s) on the surface of leukocytes. sLex participates in E-selectin-mediated leukocyte rolling and is related to the migration of leukocytes out of blood vessels .

HY-E70284

Keratanase II,bacillus circulans,expressed in E.coli	Biochemical Assay Reagents	Others
Keratanase II,bacillus circulans,expressed in E.coli has transglycosylation activity. Keratanase II,bacillus circulans,expressed in E.coli efficiently catalyzes the transglycosylation of α(2→3)-sialylated 6,6′-di-sulfo-LacNAc with two kinds of glycosyl acceptors, 6-sulfo-Lewis X and 6,6'-di-sulfo-LacNAc derivatives, providing Sialyl sulfo-hexasaccharide and Sialyl sulfo-pentasaccharide .

Cat. No.	Product Name	Type

HY-W698344

Lewis X Trisaccharide,Methyl Glycoside	Carbohydrates
Lewis X Trisaccharide,Methyl Glycoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

Lewis X Trisaccharide,Methyl Glycoside

Carbohydrates

Lewis X Trisaccharide,Methyl Glycoside is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-W145535

*Sialyl lewis* x-lactose**	Biochemical Assay Reagents
Sialyl Lewis X-Lactose is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-E70156

Fucosyltransferase 7 EC:2.4.1.-; FUT7	Enzyme Substrates
Fucosyltransferase 7 (FUT7) is a golgi stack membrane protein. Fucosyltransferase 7catalyzes the final fucosylation step in the synthesis of Lewis antigens and generates a unique glycosylated product sialyl Lewis X (sLeX). Fucosyltransferase 7 catalyzes alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens .

HY-158459

A2G2F2 glycan A2G2F2(a1-3) glycan	Carbohydrates
A2G2F2 glycan (A2G2F2(a1-3) glycan) is a Lewis X polysaccharide containing two Lewis X epitopes and is a symmetric N-glycan. SLeX is a ligand for the cell adhesion molecule E-selectin, which is specifically expressed at sites of inflammatory lesions. Designing SLeX-polysaccharide conjugates to deliver drugs to inflammatory lesions .

HY-158458

A2[3]G1F1(α-1-3) glycan A2[3]G1F1(a1-3) glycan	Carbohydrates
A2[3]G1F1(α-1-3) glycan (A2[3]G1F1(a1-3) glycan) is an asymmetric Lewis X polysaccharide and N-glycan. SLeX is a ligand for the cell adhesion molecule E-selectin, which is specifically expressed at sites of inflammatory lesions. Designing SLeX-polysaccharide conjugates to deliver drugs to inflammatory lesions .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W020790

*Sialyl-Lewis* X** sLeX	Structural Classification Polysaccharides Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Saccharides	Endogenous Metabolite
Sialyl-Lewis X (sLeX) is a sialylated fucosylated tetrasaccharide, an endogenous antigen. Sialyl-Lewis X is a high-affinity ligand for selectins (E-, P-, and L-selectin) . Sialyl-Lewis X binds to ELAM-1 and CD62 and has the ability?to inhibits CD62-mediated neutrophil recruitment to sites of inflammation .

HY-N10535

Lewis y tetrasaccharide Lewis y	Structural Classification Polysaccharides Classification of Application Fields Endogenous metabolite Disease Research Fields Saccharides Cancer	FAK
Lewis Y tetrasaccharide (Lewis Y, Le ^Y) is a tetrasaccharide derivative form of Lewis X trisaccharide (HY-N10534). Lewis Y tetrasaccharide is an antigen associated with malignant ovarian carcinomas metastasis and poor prognosis .

HY-126854

N-Acetyllactosamine N-Acetyl-D-lactosamine	Structural Classification Natural Products Microorganisms	Endogenous Metabolite
N-Acetyllactosamine (LacNAc), a nitrogen-containing disaccharide, is an important component of various oligosaccharides such as glycoproteins and sialyl Lewis X. N-Acetyllactosamine can be used as the starting material for the synthesis of various oligosaccharides. N-Acetyllactosamine has prebiotic effects .

HY-N10534

Lewis X trisaccharide Lewis X	Infection Structural Classification Natural Products Polysaccharides Animals Classification of Application Fields Inflammation/Immunology Disease Research Fields Saccharides Cancer	Parasite
Lewis X trisaccharide (Lewis X, Le ^x) is a potent T_H2 regulator, antagonizes LPS-induced IL-12 immune expression. Lewis X trisaccharide is a human histo-blood group antigen, plays an key role in cell-cell adhesion, and servers as a tumor marker. Lewis X trisaccharide is highly expressed in the outer membrane of the parasite, can be used for the immunology research of schistosomiasis .

HY-N12918

Lewis X tetrasaccharide	Structural Classification Polysaccharides Animals Source classification Saccharides	Others
Lewis X tetrasaccharide is a cell surface glycan that can be used for diagnosis of microbial infections.

HY-W145535

*Sialyl lewis* x-lactose**	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Biochemical Assay Reagents Endogenous Metabolite
Sialyl Lewis X-Lactose is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

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Biochemical Assay Reagents

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