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Results for "

NTPDase1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Interleukin Related (1) NTPDase (13) P2X Receptor (1) P2Y Receptor (1) Phosphatase (3) Pyroptosis (2)
By Research Areas:	Cancer (9) Cardiovascular Disease (6) Infection (2) Inflammation/Immunology (9) Neurological Disease (4)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-155828

*h-NTPDase-IN-4*	NTPDase	Cancer
h-NTPDase-IN-4 (compound 4c) is a pan-inhibitor of NTPDase with IC50s of 3.58 μM (h-NTPDase1), 10.21 μM (h-NTPDase2), 0.13 μM (h-NTPDase3), 13.57 μM (h- NTPDase8).

HY-103265

ARL67156 trisodium 2 Publications Verification FPL 67156 trisodium	NTPDase	Cardiovascular Disease Inflammation/Immunology
ARL67156 (FPL 67156) trisodium is a selective small molecular inhibitor, targeting to ecto-ATPase, CD39, and CD73. ARL67156 trisodium is also a competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with K_is of 11, 18 and 12?μM, respectively. ARL67156 trisodium can be used in the research of calcific aortic valve disease, asthma ^[1] .

HY-103265B

ARL67156 trisodium hydrate 2 Publications Verification FPL 67156 trisodium hydrate	NTPDase	Cardiovascular Disease Inflammation/Immunology
ARL67156 (FPL 67156) trisodium hydrate is a selective small is a selective samll molecular inhibitor, targeting to ecto-ATPase, CD39, and CD73. ARL67156 trisodium hydrate is also a competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with K_is of 11, 18 and 12?μM, respectively. ARL67156 trisodium hydrate can be used in the research of disease like calcific aortic valve disease, asthma ^[1] .

HY-103265D

ARL67156 triethylamine 2 Publications Verification FPL 67156 triethylamine	NTPDase	Cardiovascular Disease Inflammation/Immunology
ARL67156 (FPL 67156) triethylamine is a selective small is a selective samll molecular inhibitor, targeting to ecto-ATPase, CD39, and CD73. ARL67156 triethylamine is also a competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with K_is of 11, 18 and 12?μM, respectively. ARL67156 triethylamine can be used in the research of disease like calcific aortic valve disease, asthma ^[1] .

HY-103265A

ARL67156 FPL 67156	Phosphatase	Others
ARL67156 is an inhibitor of ecto-ATPase. ARL 67156 is a weak competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with K_is of 11, 18 and 12 μM, respectively ^[1].

HY-155596

*h-NTPDase-IN-1*	NTPDase	Cancer
h-NTPDase-IN-1 (Compound 3i) is a *h-NTPDase* inhibitor (IC₅₀: 2.88 μM and 0.72 μM for h-NTPDase1 and h-NTPDase3 respectively). h-NTPDase-IN-1 can be used for research of thrombosis, inflammation, diabetes, and cancer ^[1].

HY-143289

NTPDase-IN-3	NTPDase	Cardiovascular Disease Cancer
NTPDase-IN-3 (Compound 5e) is a *NTPDase* inhibitor, with IC₅₀ values of: 0.38 μM (NTPDase3), 0.05 μM (NTPDase8), 0.21 μM (NTPDase1), and 1.07 μM (NTPDase2). NTPDase-IN-3 can be used in the research of cancers and thrombosis ^[1].

HY-155829

*h-NTPDase-IN-5*	NTPDase	Others
h-NTPDase-IN-5 (compound 3b) is a pan-inhibitor of NTPDase with IC50s of 1.10 μM (h-NTPDase1), 44.73 μM (h-NTPDase2), 26.14 μM (h-NTPDase3), 0.32 μM (h- NTPDase8).

HY-155827

*h-NTPDase-IN-3*	NTPDase	Others
h-NTPDase-IN-3 (compound 4d) is a pan-inhibitor of NTPDase with IC50s of 34.13 μM (h-NTPDase1), 0.33 μM (h-NTPDase2), 23.21 μM (h-NTPDase3), 2.48 μM (h- NTPDase8).

HY-155806

*h-NTPDase-IN-2*	Phosphatase	Others
h-NTPDase-IN-2 (compound 3l) is a pan-inhibitor of h-NTPDase, with IC₅₀s of 0.35 μM (h-NTPDase1), 4.81 μM (h-NTPDase2), 37.73 μM (h-NTPDase3), 10.32 μM (h-NTPDase8), respectively ^[1].

HY-103263

PSB-06126	NTPDase	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
PSB-06126 is a selective nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitor, with the K_i values of 0.33 μM for rat NTPDase 1, 19.1 μM for NTPDase 2 and 2.22 μM for NTPDase 3, respectively. PSB-06126 acts on human NTPDase 3 with an IC₅₀ value of 7.76 μM and a K_i value of 4.39 μM ^[1] .

HY-143287

NTPDase-IN-1	NTPDase	Infection Inflammation/Immunology Cancer
NTPDase-IN-1 (compound 5a) is a selective *NTPDase* inhibitor with IC₅₀s of 0.05, 0.23 and 0.54 µM for *h-NTPDase-1/-2/-8, respectively. NTPDase-IN-1 non-competitively inhibits h-NTPDase-1/-2* with a K_m of 21 µM for *h-NTPDase-1. NTPDase*-IN-1 can be used in studies of cancer, immunologic disorders as well as bacterial infections ^[1].

HY-103262

PSB069	NTPDase	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
PSB069 bearing a p-chlorophenylamino residue is a potent, well-tolerated and nonselective NTPDases1, 2, 3 inhibitor(K_i=16~18 μM) ^[1].

HY-103259

Sodium metatungstate Maximum Cited Publications 6 Publications Verification Sodium polyoxotungstate; POM-1	Phosphatase P2X Receptor P2Y Receptor Pyroptosis Interleukin Related	Neurological Disease Inflammation/Immunology Cancer
Sodium metatungstate (Sodium polyoxotungstate) is a *NTPDase* inhibitor, with K_i values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1 (CD39), NTPDase 3 and NTPDase 2 respectively ^[1]. Sodium metatungstate has anti-inflammatory and anti-cancer effect. Sodium metatungstate inhibits ATP breakdown but also blocks central synaptic transmission ^[1] .

HY-103259A

Sodium metatungstate hydrate Sodium polyoxotungstate hydrate; POM-1 hydrate	NTPDase Pyroptosis	Neurological Disease Inflammation/Immunology Cancer
Sodium metatungstate (Sodium polyoxotungstate; POM-1) hydrate is a *NTPDase* inhibitor, with K_i values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1 (CD39), NTPDase 3 and NTPDase 2 respectively ^[1]. Sodium metatungstate has anti-inflammatory and anti-cancer effect. Sodium metatungstate inhibits ATP breakdown but also blocks central synaptic transmission ^[1] .

HY-143288

NTPDase-IN-2	NTPDase	Infection Inflammation/Immunology Cancer
NTPDase-IN-2 (compound 5g) is a selective *NTPDase* inhibitor with IC₅₀s of 0.04 and 2.27 µM for *h-NTPDase-2/-8, respectively. NTPDase-IN-2 non-competitively inhibits h-NTPDase-1/-2* with a K_m of 74 µM for *h-NTPDase-2. NTPDase*-IN-2 can be used in studies of cancer, immunologic disorders as well as bacterial infections ^[1].

Species:	Human (1) Rhesus Macaque (1) Mouse (2)
Tag:	His (4)
Source:	HEK293 (1) Sf9 insect cells (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P70727

	CD39 Protein, Mouse (HEK293, His) Ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; NTPDase 1; Ecto-ATP diphosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen; CD39	Mouse	HEK293
	The CD39 protein is expressed in the nervous system and regulates purinergic neurotransmission by hydrolyzing ATP and other nucleotides. It also prevents platelet aggregation by hydrolyzing platelet-activated ADP to AMP. CD39 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD39 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD39 Protein, Mouse (HEK293, His) is 441 a.a., with molecular weight of 60-90 kDa.

HY-P75417

	CD39 Protein, Human (sf9, His) Ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; Ecto-apyrase; CD39; Entpd1	Human	Sf9 insect cells
	The CD39 protein is an important regulator in the nervous system, coordinating purinergic neurotransmission by hydrolyzing ATP and other nucleotides. Its enzymatic ability can hydrolyze platelet-activated ADP into AMP, thereby effectively preventing platelet aggregation. CD39 Protein, Human (sf9, His) is the recombinant human-derived CD39 protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P72898

	CD39 Protein, Mouse (His) Ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; Ecto-apyrase; CD39; Entpd1	Mouse	Sf9 insect cells
	The CD39 protein is expressed in the nervous system and regulates purinergic neurotransmission by hydrolyzing ATP and other nucleotides. It also prevents platelet aggregation by hydrolyzing platelet-activated ADP to AMP. CD39 Protein, Mouse (His) is the recombinant mouse-derived CD39 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of CD39 Protein, Mouse (His) is 441 a.a., with molecular weight of ~51 kDa.

HY-P76801

	CD39 Protein, Cynomolgus/Rhesus Macaque (sf9, His) Ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; Ecto-apyrase; CD39; Entpd1	Rhesus Macaque	Sf9 insect cells
	ENTPD1 is an integral membrane protein with an extracellular active site. ENTPD1 hydrolyzes the beta - and gamma phosphate residues of nucleotides, preferring ATP as the substrate. Through its hydrolysis of extracellular nucleotides, ENTPD1 plays a role in the regulation of purinergic signaling. CD39 Protein, Cynomolgus/Rhesus Macaque (sf9, His) is the recombinant Rhesus Macaque-derived CD39 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of CD39 Protein, Cynomolgus/Rhesus Macaque (sf9, His) is 441 a.a., with molecular weight of ~51.8 KDa.

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HY-P81349

	CD39 Antibody (YA1094) CD39; ENTPD1; Ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; Ecto-ATP diphosphohydrolase 1 (Ecto-ATPDase 1; Ecto-ATPase 1); Ecto-apyrase; Lymphoid cell activation antigen	IHC-P	Human
	CD39 Antibody (YA1094) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1094), targeting CD39. CD39 Antibody (YA1094) can be used for IHC-P experiment in human background.

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