2. Immunology/Inflammation
  3. NTPDase
  4. h-NTPDase-IN-4

h-NTPDase-IN-4 (compound 4c) is a pan-inhibitor of NTPDase with IC50s of 3.58 μM (h-NTPDase1), 10.21 μM (h-NTPDase2), 0.13 μM (h-NTPDase3), 13.57 μM (h- NTPDase8).

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h-NTPDase-IN-4 Chemical Structure

h-NTPDase-IN-4 Chemical Structure

CAS No. : 2939933-09-0

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5 mg USD 179 In-stock
10 mg USD 287 In-stock
25 mg USD 574 In-stock
50 mg USD 914 In-stock
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Based on 1 publication(s) in Google Scholar

h-NTPDase-IN-4 Related Antibodies

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Description

h-NTPDase-IN-4 (compound 4c) is a pan-inhibitor of NTPDase with IC50s of 3.58 μM (h-NTPDase1), 10.21 μM (h-NTPDase2), 0.13 μM (h-NTPDase3), 13.57 μM (h- NTPDase8).

IC50 & Target

IC50: 3.58 μM (h-NTPDase1), 10.21 μM (h-NTPDase2), 0.13 μM (h-NTPDase3), 13.57 μM (h- NTPDase8)
Molecular Weight

560.36

Formula

C22H8F12N2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

FC(C1=CC(C2=NC=NC3=C2SC=C3C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)=CC(C(F)(F)F)=C1)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMF : 100 mg/mL (178.46 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7846 mL 8.9228 mL 17.8457 mL
5 mM 0.3569 mL 1.7846 mL 3.5691 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMF 1 mM 1.7846 mL 8.9228 mL 17.8457 mL 44.6142 mL
5 mM 0.3569 mL 1.7846 mL 3.5691 mL 8.9228 mL
10 mM 0.1785 mL 0.8923 mL 1.7846 mL 4.4614 mL
15 mM 0.1190 mL 0.5949 mL 1.1897 mL 2.9743 mL
20 mM 0.0892 mL 0.4461 mL 0.8923 mL 2.2307 mL
25 mM 0.0714 mL 0.3569 mL 0.7138 mL 1.7846 mL
30 mM 0.0595 mL 0.2974 mL 0.5949 mL 1.4871 mL
40 mM 0.0446 mL 0.2231 mL 0.4461 mL 1.1154 mL
50 mM 0.0357 mL 0.1785 mL 0.3569 mL 0.8923 mL
60 mM 0.0297 mL 0.1487 mL 0.2974 mL 0.7436 mL
80 mM 0.0223 mL 0.1115 mL 0.2231 mL 0.5577 mL
100 mM 0.0178 mL 0.0892 mL 0.1785 mL 0.4461 mL
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h-NTPDase-IN-4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

h-NTPDase-IN-42939933-09-0NTPDaseInhibitorinhibitorinhibit

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