2. Immunology/Inflammation
  3. NTPDase
  4. NTPDase-IN-2

NTPDase-IN-2 (compound 5g) is a selective NTPDase inhibitor with IC50s of 0.04 and 2.27 µM for h-NTPDase-2/-8, respectively. NTPDase-IN-2 non-competitively inhibits h-NTPDase-1/-2 with a Km of 74 µM for h-NTPDase-2. NTPDase-IN-2 can be used in studies of cancer, immunologic disorders as well as bacterial infections.

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NTPDase-IN-2 Chemical Structure

NTPDase-IN-2 Chemical Structure

CAS No. : 2883147-47-3

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NTPDase-IN-2 Related Antibodies

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Description

NTPDase-IN-2 (compound 5g) is a selective NTPDase inhibitor with IC50s of 0.04 and 2.27 µM for h-NTPDase-2/-8, respectively. NTPDase-IN-2 non-competitively inhibits h-NTPDase-1/-2 with a Km of 74 µM for h-NTPDase-2. NTPDase-IN-2 can be used in studies of cancer, immunologic disorders as well as bacterial infections[1].

IC50 & Target

h-NTPDase-2

0.04 μM (IC50)

h-NTPDase-8

2.27 μM (IC50)

h-NTPDase-1

＞100 μM (IC50)

h-NTPDase-3

＞100 μM (IC50)

Molecular Weight

449.56

Formula

C24H20FN3OS2
CAS No.
SMILES

CC(C1=CC=C(C(F)=C1)C2=CC=CC=C2)C(NC3=NN=C(S3)SCC4=CC=CC=C4)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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NTPDase-IN-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NTPDase-IN-22883147-47-3NTPDaseh-NTPDaseextracellular nucleotidesEcto-ATPasesATPcancerimmunologic disordersL. pneumophilaInhibitorinhibitorinhibit

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