RD | MedChemExpress (MCE) Life Science Reagents

By Targets:	ADC Linker (1) Androgen Receptor (1) Apoptosis (3) Bacterial (2) Biochemical Assay Reagents (1) Calcium Channel (1) CDK (1) COX (1) Cytochrome P450 (1) Dopamine Receptor (2) Drug Metabolite (1) Endogenous Metabolite (3) Enterovirus (3) HSP (1) Isotope-Labeled Compounds (5) NF-κB (1) PKC (1) Reactive Oxygen Species (1) RSV (1) Small Interfering RNA (siRNA) (3) Src (1)
By Research Areas:	Cancer (6) Cardiovascular Disease (1) Infection (4) Inflammation/Immunology (6) Metabolic Disease (1) Neurological Disease (1)
Click Chemistry:	Tetrazine (1)
Oligonucleotides:	Pre-designed siRNA Sets (3) siRNAs (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-111145

RD162	Androgen Receptor	Cancer
RD162, a diarylthiohydantoin, is an orally active non-steroidal antiandrogen (NSAA). RD162 specifically binds to androgen receptor (AR). RD162 induces tumor regression in mouse models of castration-resistant human prostate cancer .

HY-U00190

Deprodone propionate RD20000	Bacterial	Inflammation/Immunology
Deprodone propionate (RD20000) is a corticosteroid which is obtained by esterifying with propionic acid the 17-position of the prednisolone skeleton and deoxidating its 21-position.

HY-N2516

Ginsenoside Rd2	Others	Inflammation/Immunology
Ginsenoside Rd2 is a saponin found in Panax japonicus with anti-inflammatory actions .

HY-N0043

Ginsenoside Rd Gypenoside VIII	NF-κB COX Calcium Channel Cytochrome P450 Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Cancer
Ginsenoside Rd inhibits TNFα-induced NF-κB transcriptional activity with an IC₅₀ of 12.05±0.82 μM in HepG2 cells. Ginsenoside Rd inhibits expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca ²⁺ influx. Ginsenoside Rd inhibits CYP2D6, CYP1A2, CYP3A4, and CYP2C9, with IC₅₀s of 58.0±4.5 μM, 78.4±5.3 μM, 81.7±2.6 μM, and 85.1±9.1 μM, respectively.

HY-100285

RD3-0028	RSV	Infection
RD3-0028 is a potent and selective inhibitor of RSV replication with an EC₅₀ of 4.5 μM.

HY-RS11796

RD3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
RD3 Human Pre-designed siRNA Set A contains three designed siRNAs for RD3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

RD3 Human Pre-designed siRNA Set A RD3 Human Pre-designed siRNA Set A

HY-RS11797

RD3L Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
RD3L Human Pre-designed siRNA Set A contains three designed siRNAs for RD3L gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

RD3L Human Pre-designed siRNA Set A RD3L Human Pre-designed siRNA Set A

HY-N4263

5,6-Didehydroginsenoside Rd	Others	Inflammation/Immunology
5,6-Didehydroginsenoside Rd is a dammarane-type saponin isolated from the dried roots of Panax notoginseng .

HY-RS06705

IL17RD Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
IL17RD Human Pre-designed siRNA Set A contains three designed siRNAs for IL17RD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

IL17RD Human Pre-designed siRNA Set A IL17RD Human Pre-designed siRNA Set A

HY-162715

EV-A71-IN-2	Enterovirus	Infection
EV-A71-IN-2 (compound 6c) is a anti-EV-A71 agent with the EC₅₀ values of 0.29 μM and 1.66 μM aganist of EV-A71-MRC-5 cells and EV-A71-RD cells, respectively. EV-A71-IN-2 can be used for study of enterovirus infection .

HY-14328

Sonepiprazole PNU-101387G; U-101387G	Dopamine Receptor	Neurological Disease
Sonepiprazole (PNU-101387G) is a selective D4 dopamine antagonist with K_is of 3.6, 10.1, 5147, and 7430 nM for rD4-Dopamine, hD4.2-Dopamine, rD2-Dopamine, and Histamine-H1 receptors, respectively .

HY-161687

Cisplatin/Dasatinib prodrug-1	Src	Cancer
Cisplatin/Dasatinib prodrug-1 (Compound 3) is a prodrug of Cisplatin (HY-17394) and Dasatinib (HY-10181). Cisplatin/Dasatinib prodrug-1 exhibits antiproliferative activity against A2780, MDA-MB-231, MCF7, HCT116, RD, Thp1 and HL60 cancer cells with IC₅₀s of 0.1, 0.1, 0.36, 2.0, 0.4, 0.3 and 0.25 μM, respectively .

HY-146899S

CER6-2’R-d9	Isotope-Labeled Compounds	Others
CER6-2’R-d₉ is deuterium labeled CER6-2’R.

HY-146909S

CER5-2’R-d9	Isotope-Labeled Compounds	Others
CER5-2’R-d₉ is deuterium labeled CER5-2’R.

HY-146938S

CER11-2’R-d9	Isotope-Labeled Compounds	Others
CER11-2’R-d₉ is deuterium labeled CER11-2’R.

HY-151686

Bz-(Me)Tz-NHS	ADC Linker	Others
Bz-(Me)Tz-NHS is a click chemistry reagent containing an methyltetrazine group. Bz-(Me)Tz-NHS is 3rd generation Click-Linker for Cu-free click conjugation .

HY-146939S

CER7-2’R,6R-d9	Isotope-Labeled Compounds	Others
CER7-2’R,6R-d₉ is deuterium labeled CER7-2’R,6R.

HY-146940S

CER7-2’S,6R-d9	Isotope-Labeled Compounds	Others
CER7-2’S,6R-d₉ is deuterium labeled CER7-2’S,6R.

HY-W016407

Methyl 3,4-dihydroxyphenylacetate	Enterovirus	Infection
Methyl 3,4-dihydroxyphenylacetate is a potent enterovirus 71 (EV71) infection inhibitor. Methyl 3,4-dihydroxyphenylacetate inhibits EV71 replication in rhabdomyosarcoma (RD) cells .

HY-101065

AJ-76 hydrochloride (+)-AJ 76 hydrochloride; (1S,2R)-AJ 76 hydrochloride	Dopamine Receptor	Others
AJ-76 hydrochloride ((+)-AJ 76 hydrochloride) is an antagonist of dopamine autoreceptor with pK_i values of 6.95, 6.67, 6.37, 6.21 and 6.07 for hD3, hD4, hD2S, hD2L and rD2 receptors, respectively.

HY-12933

BIIB-028	HSP	Cancer
BIIB-028 is an orally active inhibitor for heat shock protein 90 (Hsp90). BIIB-028 targets the ATP-binding site of Hsp90, disrupts the function of Hsp90, leads to the degradation of client proteins, that are crucial for cancer cell survival and proliferation .

HY-W019806

Lacto-N-fucopentaose I LNFP I	Endogenous Metabolite CDK Reactive Oxygen Species Apoptosis Enterovirus Bacterial	Infection Inflammation/Immunology
Lacto-N-fucopentaose I (LNFPI) is a human milk oligosaccharide (HMO), possessing antiviral and antibacterial activity. Lacto-N-fucopentaose I can reduce capsid protein VP1 to block virus adsorption, promote CDK2 and reduce cyclin E to recover cell cycle S phase block. Lacto-N-fucopentaose I inhibits ROS production and apoptosis in virus-infected cells. Lacto-N-fucopentaose I can also regulate intestinal microbiota to affect immune system development .

HY-W017567

Ethyl (E)-2-hexenoate trans-2-Hexenoic Acid Ethyl Ester	Biochemical Assay Reagents	Others
Ethyl (E)-2-hexenoate consists of a six-carbon chain with a double bond between the 2nd and 3rd carbon atoms, an ethyl ester group attached to the 1st carbon atom, and a A methyl group connected by 4 carbon atoms. This compound has a fruity, sweet or floral aroma and is commonly used as a flavoring in foods such as baked goods, confectionary and beverages.

HY-117800

BJE6-106 1 Publications Verification B106	PKC Apoptosis	Inflammation/Immunology Cancer
BJE6-106 (B106) is a potent, selective 3 ^rd generation PKCδ inhibitor with an IC₅₀ of 0.05 μM and targets selectivity over classical PKC isozyme PKCα (IC₅₀=50 μM). BJE6-106 (B106) induces caspase-dependent apoptosis. BJE6-106 (B106) possesses tumor-specific effect.

HY-150968

Antiproliferative agent-11	Apoptosis	Cancer
Antiproliferative agent-11 (compound 7) is an antiproliferative and selective Ruthenium(II)-Tris-pyrazolylmethane complex. Antiproliferative agent-11 shows antiproliferative activity towards MCF-7, HeLa, 518A2, HCT116 and RD with IC₅₀s of 6, 10, 6.8, 6.7 and 6 μM, respectively. Antiproliferative agent-11 can be used for the research of cancer .

HY-14925

Lapaquistat 1 Publications Verification T-91485	Endogenous Metabolite Drug Metabolite	Metabolic Disease
Lapaquistat (T-91485), a cholesterol biosynthesis inhibitor, is the active metabolite of Lapaquistat acetate (HY-16274). Lapaquistat can decrease statin-induced myotoxicity in lipid-lowering therapy .

Cat. No.	Product Name	Type

HY-W017567

Ethyl (E)-2-hexenoate trans-2-Hexenoic Acid Ethyl Ester	Drug Delivery
Ethyl (E)-2-hexenoate consists of a six-carbon chain with a double bond between the 2nd and 3rd carbon atoms, an ethyl ester group attached to the 1st carbon atom, and a A methyl group connected by 4 carbon atoms. This compound has a fruity, sweet or floral aroma and is commonly used as a flavoring in foods such as baked goods, confectionary and beverages.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2516

Ginsenoside Rd2	Panax ginseng C. A. Meyer Triterpenes Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Inflammation/Immunology Araliaceae	Others
Ginsenoside Rd2 is a saponin found in Panax japonicus with anti-inflammatory actions .

HY-N0043

Ginsenoside Rd Gypenoside VIII	Panax ginseng C. A. Meyer Cardiovascular Disease Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Plants Endogenous metabolite Disease Research Fields Araliaceae Cancer	NF-κB COX Calcium Channel Cytochrome P450 Endogenous Metabolite
Ginsenoside Rd inhibits TNFα-induced NF-κB transcriptional activity with an IC₅₀ of 12.05±0.82 μM in HepG2 cells. Ginsenoside Rd inhibits expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca ²⁺ influx. Ginsenoside Rd inhibits CYP2D6, CYP1A2, CYP3A4, and CYP2C9, with IC₅₀s of 58.0±4.5 μM, 78.4±5.3 μM, 81.7±2.6 μM, and 85.1±9.1 μM, respectively.

HY-W019806

Lacto-N-fucopentaose I LNFP I	Infection Structural Classification Natural Products Polysaccharides Classification of Application Fields Animals Inflammation/Immunology Disease Research Fields Saccharides	Endogenous Metabolite CDK Reactive Oxygen Species Apoptosis Enterovirus Bacterial
Lacto-N-fucopentaose I (LNFPI) is a human milk oligosaccharide (HMO), possessing antiviral and antibacterial activity. Lacto-N-fucopentaose I can reduce capsid protein VP1 to block virus adsorption, promote CDK2 and reduce cyclin E to recover cell cycle S phase block. Lacto-N-fucopentaose I inhibits ROS production and apoptosis in virus-infected cells. Lacto-N-fucopentaose I can also regulate intestinal microbiota to affect immune system development .

HY-14925

Lapaquistat 1 Publications Verification T-91485	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Drug Metabolite
Lapaquistat (T-91485), a cholesterol biosynthesis inhibitor, is the active metabolite of Lapaquistat acetate (HY-16274). Lapaquistat can decrease statin-induced myotoxicity in lipid-lowering therapy .

HY-N4263

5,6-Didehydroginsenoside Rd	Panax ginseng C. A. Meyer Triterpenes Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Inflammation/Immunology Araliaceae	Others
5,6-Didehydroginsenoside Rd is a dammarane-type saponin isolated from the dried roots of Panax notoginseng .

Species:	Human (3) Mouse (2) Canine (2)
Tag:	His (5) Tag Free (1) Fc (1)
Source:	HEK293 (5) CHO (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P70896

	ERMAP Protein, Human (HEK293, His) Erythroid Membrane-Associated Protein; hERMAP; Radin Blood Group Antigen; Scianna Blood Group Antigen; ERMAP; RD; SC	Human	HEK293
	ERMAP protein potentially serves as a cell-adhesion or receptor molecule in erythroid cells, suggesting involvement in crucial interactions or signaling events. The precise mechanisms, ligands, and broader implications of ERMAP's activity in erythroid cell biology require further investigation. Unraveling ERMAP's function may provide insights into its significance in hematopoiesis and related physiological processes. ERMAP Protein, Human (HEK293, His) is the recombinant human-derived ERMAP protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P72794

	IL-17RD Protein, Mouse (CHO) Interleukin-17 receptor D; IL-17 receptor D; IL-17RD; mSef; Il17RD; Sef	Mouse	CHO
	Interleukin-17 receptor D (IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a type I transmembrane protein that can regulate several signaling pathways. Within the cell, IL-17RD expression has been localized mainly to the plasma membrane. IL-17RD is a feedback inhibitor of fibroblast growth factor (FGF) signaling. IL-17RD Protein, Mouse (CHO) is produced in CHO cells, and consists of 2713 amino acids (G29-R299).

HY-P75840

	IL-17RD Protein, Canine (HEK293, His) Interleukin-17 receptor D; IL-17RD; IL17Rhom; hSef; IL17RLM; SEF	Canine	HEK293
	Interleukin-17 receptor D (IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a type I transmembrane protein that can regulate several signaling pathways. Within the cell, IL-17RD expression has been localized mainly to the plasma membrane. IL-17RD is a feedback inhibitor of fibroblast growth factor (FGF) signaling. IL-17RD Protein, Canine (HEK293, His) is produced in HEK293 cells with a His-Terminal Fc-tag.

HY-P701073

	Tubby Protein, Human (His) Tubby protein homolog; TUB; RD5; RDOB	Human	E. coli
	Tubby, implicated in G protein-coupled receptor signaling, binds phosphatidylinositol 4,5-bisphosphate on membranes and may play a role in nuclear transcription regulation. Potentially involved in hypothalamic weight regulation and contributes to phagocytosis of apoptotic cells. Interacts with GNAQ and TULP1. Tubby Protein, Human (His) is the recombinant human-derived Tubby protein, expressed by E. coli , with N-His labeled tag. The total length of Tubby Protein, Human (His) is 506 a.a., with molecular weight of 56.74 kDa.

HY-P72579

	IL-17RD Protein, Mouse (HEK293, His) Interleukin-17 receptor D; IL-17RD; IL17Rhom; hSef; IL17RLM; SEF	Mouse	HEK293
	Interleukin-17 receptor D (IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a type I transmembrane protein that can regulate several signaling pathways. Within the cell, IL-17RD expression has been localized mainly to the plasma membrane. IL-17RD is a feedback inhibitor of fibroblast growth factor (FGF) signaling. IL-17RD Protein, Mouse (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags.

HY-P75839

	IL-17RD Protein, Canine (HEK293, Fc) Interleukin-17 receptor D; IL-17RD; IL17Rhom; hSef; IL17RLM; SEF	Canine	HEK293
	Interleukin-17 receptor D (IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a type I transmembrane protein that can regulate several signaling pathways. Within the cell, IL-17RD expression has been localized mainly to the plasma membrane. IL-17RD is a feedback inhibitor of fibroblast growth factor (FGF) signaling. IL-17RD Protein, Canine (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag.

HY-P72578

	IL-17RD Protein, Human (283a.a, HEK293, His) Interleukin-17 receptor D; IL-17RD; IL17Rhom; hSef; IL17RLM; SEF	Human	HEK293
	Interleukin-17 receptor D (IL-17RD) also known as Sef (similar expression to fibroblast growth factor), is a type I transmembrane protein that can regulate several signaling pathways. Within the cell, IL-17RD expression has been localized mainly to the plasma membrane. IL-17RD is a feedback inhibitor of fibroblast growth factor (FGF) signaling. IL-17RD Protein, Human (283a.a, HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags. It consists of 283 amino acids (C17-R299).

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure

HY-146899S

CER6-2’R-d9
CER6-2’R-d₉ is deuterium labeled CER6-2’R.

HY-146909S

CER5-2’R-d9
CER5-2’R-d₉ is deuterium labeled CER5-2’R.

HY-146938S

CER11-2’R-d9
CER11-2’R-d₉ is deuterium labeled CER11-2’R.

HY-146939S

CER7-2’R,6R-d9
CER7-2’R,6R-d₉ is deuterium labeled CER7-2’R,6R.

HY-146940S

CER7-2’S,6R-d9
CER7-2’S,6R-d₉ is deuterium labeled CER7-2’S,6R.

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P81620

	NELFE Antibody (YA1365) RD; RDP; RDBP; D6S45; NELF-E	WB, IHC-P, IP	Human, Mouse, Rat
	NELFE Antibody (YA1365) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1365), targeting NELFE, with a predicted molecular weight of 43 kDa (observed band size: 43 kDa). NELFE Antibody (YA1365) can be used for WB, IHC-P, IP experiment in human, mouse, rat background.

HY-P83565

	RPE65 Antibody (YA3310) LCA2; mRPE65; p63; RD12; Retinal pigment epithelium specific 61 kDa protein; RP20; RPE65; sRPE65	WB, IP	Human, Mouse, Rat
	RPE65 Antibody (YA3310) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3310), targeting RPE65, with a predicted molecular weight of 61 kDa (observed band size: 61 kDa). RPE65 Antibody (YA3310) can be used for WB, IP experiment in human, mouse, rat background.

HY-P81435

	SLC1A5/ASCT2 Antibody (YA1180) SLC1A5 ; ASCT2; M7V1, RDR, RDRC; Neutral amino acid transporter B(0); ATB(0); Baboon M7 virus receptor; RD114/simian type D retrovirus receptor; Sodium-dependent neutral amino acid transporter type 2; Solute carrier family 1 member 5	IHC-P	Human
	SLC1A5/ASCT2 Antibody (YA1180) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1180), targeting SLC1A5/ASCT2. SLC1A5/ASCT2 Antibody (YA1180) can be used for IHC-P experiment in human background.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-151686

Bz-(Me)Tz-NHS		Tetrazine
Bz-(Me)Tz-NHS is a click chemistry reagent containing an methyltetrazine group. Bz-(Me)Tz-NHS is 3rd generation Click-Linker for Cu-free click conjugation .

Cat. No.	Product Name		Classification

HY-RS11796

RD3 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
RD3 Human Pre-designed siRNA Set A contains three designed siRNAs for RD3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS11797

RD3L Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
RD3L Human Pre-designed siRNA Set A contains three designed siRNAs for RD3L gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS06705

IL17RD Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
IL17RD Human Pre-designed siRNA Set A contains three designed siRNAs for IL17RD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

RD

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides