RPE65 Antibody (YA3310)

RPE65 Antibody (YA3310) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3310), targeting RPE65, with a predicted molecular weight of 61 kDa (observed band size: 61 kDa). RPE65 Antibody (YA3310) can be used for WB, IP experiment in human, mouse, rat background.

The protein encoded by The related gene is a component of the vitamin A visual cycle of the retina which supplies the 11-cis retinal chromophore of the photoreceptors opsin visual pigments. It is a member of the carotenoid cleavage oxygenase superfamily. All members of The superfamily are non-heme iron oxygenases with a seven-bladed propeller fold and oxidatively cleave carotenoid carbon:carbon double bonds. However, the protein encoded by The related gene has acquired a divergent function that involves the concerted O-alkyl ester cleavage of its all-trans retinyl ester substrate and all-trans to 11-cis double bond isomerization of the retinyl moiety. As such, it performs the essential enzymatic isomerization step in the synthesis of 11-cis retinal. Mutations in The related gene are associated with early-onset severe blinding disorders such as Leber congenital.

6121

Predicted band size: 61 kDa; Observed band size: 61 kDa

Affinity Chromatography

Non-conjugated

Unmodified

Tags & Cell Markers

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Recombinant, Monoclonal

Rabbit

Human, Mouse, Rat

Q16518

WB: 1/500-1/1000;IP: 1/50

WB, IP

Liquid

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Endogenous

A synthesized peptide derived from human RPE65