2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. HSP
  4. BIIB-028

BIIB-028 is an orally active inhibitor for heat shock protein 90 (Hsp90). BIIB-028 targets the ATP-binding site of Hsp90, disrupts the function of Hsp90, leads to the degradation of client proteins, that are crucial for cancer cell survival and proliferation.

For research use only. We do not sell to patients.

BIIB-028 Chemical Structure

BIIB-028 Chemical Structure

CAS No. : 911398-13-5

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BIIB-028 Related Antibodies

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Description

BIIB-028 is an orally active inhibitor for heat shock protein 90 (Hsp90). BIIB-028 targets the ATP-binding site of Hsp90, disrupts the function of Hsp90, leads to the degradation of client proteins, that are crucial for cancer cell survival and proliferation[1][2].

Molecular Weight

465.83

Formula

C19H21ClN5O5P
CAS No.
SMILES

CC(C(OC)=C(C)C=N1)=C1CN2C3=NC(N)=NC(Cl)=C3C(C#CCCOP(O)(O)=O)=C2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BIIB-028 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BIIB-028911398-13-5BIIB028BIIB 028HSPHeat shock proteinsGeldanamycinGAradicicolRDorally activeInhibitorinhibitorinhibit

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