Search Result
Results for "
fractionation
" in MedChemExpress (MCE) Product Catalog:
5
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-125361
-
|
|
Others
|
Others
|
|
Ganosporeric acid A, a natural product, is isolated from the ether-soluble fraction of the spores of Ganoderma lucidum. Ganosporeric acid A can be used for the research of liver injury .
|
-
-
- HY-138560
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cross-linked dextran G 50 is a gel filtration medium. Cross-linked dextran G 50 can be used in gel permeation chromatography for fractionation of the glycopeptide mixture (Sphere protein separation range: 1.5K-30K Da; Polysaccharide separation range: 500-10K Da) .
|
-
-
- HY-N3621
-
|
|
Others
|
Others
|
|
Corchoionol C is a n-butanol-soluble fraction of the whole plant extract of Pulicaria undulate .
|
-
-
- HY-N8977
-
|
|
Others
|
Others
|
|
4-O-Methylgrifolic acid is a farnesylphenols that can be isolated from the lipophilic fraction of Polyporus dispansus .
|
-
-
- HY-160658
-
|
|
CCR
|
Inflammation/Immunology
|
|
AZ760 is a CCR8 antagonist. AZ760 shows excellent potency, good lipophilicity and high free fraction in blood. AZ760 exhibits unacceptable hERG inhibition .
|
-
-
- HY-157538
-
|
|
PDHK
|
Cardiovascular Disease
|
|
PDK4-IN-2 (compound 8) is a pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 of 46 µM. PDK4-IN-2 improves ejection fraction of failing hearts by regulating bioenergetics via activation of the tricarboxylic acid cycle .
|
-
-
- HY-P5700
-
|
|
Bacterial
|
Infection
|
|
SAAP Fraction 3 is an antimicrobial peptide. SAAP Fraction 3 is active against P. haemolytica in Zn-saline buffer .
|
-
-
- HY-156980
-
-
-
- HY-N4245
-
|
|
Others
|
Others
|
|
Siegesmethyletheric acid is isolated from the ethyl acetate fraction of Siegesbeckia orientalis L. (Asteraceae) .
|
-
-
- HY-N0860
-
|
Schizantherin-E
|
Others
|
Inflammation/Immunology
|
|
Schisantherin E is a natural compound isolated from the active fraction of the fruits of Schisandra sphenanthera Rehd. et Wils.
|
-
-
- HY-N5073
-
-
-
- HY-N9379
-
|
|
Others
|
Others
|
|
Fissistigine A is an alkaloid separated of the basic fractions from Formosan Fissistigma glaucescens, F. oldhamii and Goniothalamus amuyon .
|
-
-
- HY-N12039
-
|
|
Others
|
Others
|
|
Juniper camphor is a sesquiterpene compound isolated from camphor blue oil, the high-boiling fraction of camphor .
|
-
-
- HY-N12352
-
|
|
Others
|
Others
|
|
Eschweilenol C is a compound derivative ellagic acid from the aqueous fraction of the ethanolic extract of Terminalia fagifolia Mart. .
|
-
-
- HY-116547
-
|
4,5-Methylenephenanthrene
|
Others
|
Others
|
|
Methylenephenanthrene (4,5-Methylenephenanthrene) can be isolated from the refined neutral fraction of anthracene oil
|
-
-
- HY-B0399A
-
|
(±)-Carnitin
|
Mitochondrial Metabolism
|
Metabolic Disease
|
|
DL-Carnitine is a racemic mixture of L-Carnitine and D-Carnitine, regulates fatty acid transport in mitochondria, elevates serum carnitine fractions.
|
-
-
- HY-N3955
-
|
Glutinone; Glutinone
|
Others
|
Others
|
|
Alnusenone (Glutinone) is a stabilised intermediate int he biogenesis of friedelin (XV) from squalene. Alnusenone is the major natural compound in fractions .
|
-
-
- HY-118852
-
|
|
Others
|
Others
|
|
Isoxaben, a herbicide, inhibits incorporation of radiolabeled glucose into an acid insoluble cell wall fraction. Isoxaben is also a specific inhibitor of cell wall biosynthesis .
|
-
-
- HY-N11011
-
|
|
Others
|
Inflammation/Immunology
|
|
Withaphysalin A is a withanolide-type compound. Withaphysalin A can be obtained from the anti-inflammatory fraction of P. minima. Withaphysalin A can be used for the research of inflammation .
|
-
-
- HY-W145695
-
|
|
Biochemical Assay Reagents
|
Inflammation/Immunology
|
|
Chitoheptaose is a chitosan oligosaccharide. Chitoheptaose is capable of extracting exoskeletons from crustaceans, such as the shells of crabs, shrimp and lobsters. Chitoheptaose has antioxidant, anti-inflammatory and anti-apoptotic activities and can be used in the study of myocarditis. Chitoheptaose has cardioprotective effects and improves cardiac parameters (left ventricular internal size, end-systolic and end-diastolic, ejection fraction and shortening fraction), inflammatory cytokines (IL-1β) in vanishing models .
|
-
-
- HY-N0786
-
|
|
Others
|
Neurological Disease
|
|
Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC50 range of 12-54 μM, has neuroprotective and anti neuronal apoptotic ability .
|
-
-
- HY-133610
-
|
|
Others
|
Others
|
|
3,4,6-trichlorocatechol (TCC) is the metabolite produced by industrial pollutant through post-mitochondrial liver fraction from Aroclor-1254 induced rats .
|
-
-
- HY-N12551
-
|
|
Others
|
Others
|
|
2-O-β-D-Glucopyranosylcucurbitacin F 25-acetate is a cucurbitacin glucoside that can isolated from the more polar fractions of the MeOH extract of Cigarrilla mexicana .
|
-
-
- HY-Y1422D
-
|
|
Others
|
Others
|
|
Lipase 435, an immobilized lipase derived from Candida antarctica fraction B, shows extensive industrial application in producing enantiopure pharmaceuticals, functional lipids, biodiesel, etc. .
|
-
-
- HY-112738
-
|
|
Phospholipase
|
Inflammation/Immunology
|
|
AX048 is an inhibitor for calcium-dependent phospholipase A2 cPLA2 with a XI(50) of 0.022 mole fraction and reveals an antihyperalgesic efficacy .
|
-
-
- HY-137295
-
|
|
PKC
Apoptosis
|
Inflammation/Immunology
|
|
Ingenol 3,20-dibenzoate is a potent protein kinase C (PKC) isoform-selective agonist. Ingenol 3,20-dibenzoate induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the particulate fraction and induces morphologically typical apoptosis through de novo synthesis of macromolecules. Ingenol 3,20-dibenzoate increases the IFN-γ production and degranulation by NK cells, especially when NK cells are stimulated by NSCLC cells .
|
-
-
- HY-N9900
-
|
Demethyldaphnoretin-7-O-β-D-glucopyranoside
|
Others
|
Others
|
|
Demethyldaphnoretin-7-O-β-Dglucopyranoside (Demethyldaphnoretin-7-O-glucoside)(compound 1) is a natural product isolated from the ethyl acetate fraction of the roots of Daphne oleoides .
|
-
-
- HY-121388
-
|
(+)-Ledol
|
Fungal
|
Infection
|
|
Ledol ((+)-Ledol) is an antifungal agent that can be isolated from the essential oil fractions of Rhododendron tomentosum. Ledol is also the expectorant and antitussive agent, which is simultaneously responsible for adverse reactions such as dizziness, nausea and vomiting .
|
-
-
- HY-W009934
-
|
α-Phenyl-2-pyridineacetonitrile
|
Drug Metabolite
|
Endocrinology
|
|
2-Phenyl-2-(2-pyridyl)acetonitrile is the major metabolite of SC 15396 metabolized by the supernatant fraction of rat liver homogenate. SC 15396 is an antigastrin that inhibits gastric secretion .
|
-
-
- HY-P1495
-
-
-
- HY-N3433
-
|
|
Others
|
Others
|
|
Kaempferol 3-O-arabinoside is an antioxidant flavonoids isolated from ethyl acetate fraction (EAF) obtained from the leaves of Nectandra hihua. Kaempferol 3-O-arabinoside has good antioxidant capacity .
|
-
-
- HY-N1014
-
|
|
Others
|
Others
|
|
11α,12β-Di-O-acetyltenacigenin B is a polyoxypregnane compound isolated from the CHCl(3)-soluble fraction of the ethanolic extract of the stem of Marsdenia tenacissima .
|
-
-
- HY-W011120
-
|
|
Others
|
Metabolic Disease
|
|
Ethyl cis-4,7,10,13,16,19-Docosahexaenoate, the ethyl ester of Docosahexaenoate (DHA), is enriched in the ethyl ester fraction by the selective alcoholysis of fatty acid ethyl esters originating from tuna oil with lauryl alcohol.
|
-
-
- HY-153168
-
|
|
Phosphodiesterase (PDE)
|
Cardiovascular Disease
|
|
Bemoradan (compound 10a) is an orally active and selective canine Phosphodiesterase (PDE) fraction III inhibitor. Bemoradan is a long-acting, potent, inotropic vasodilator and a novel cardiotonic agent, and can be used in congestive heart
failure research .
|
-
-
- HY-W102714
-
|
CDTA
|
Others
|
Metabolic Disease
|
|
1,2-Cyclohexylenedinitrilotetraacetic acid (CDTA) is a chelating agent. 1,2-Cyclohexylenedinitrilotetraacetic acid has an ability to remove manganese from brain and liver (in vivo) and their sub-cellular fractions (in vitro), of rats pretreated with manganese sulphate .
|
-
-
- HY-163079
-
|
|
FAP
|
Cancer
|
|
AlF-PD-FAPI has affinity for FAP , with the IC50 of 0.13 nM, and shows a specific uptake, high internalized fraction, and low cellular efflux in vitro. AlF-PD-FAPI can be used as FAP-targeting tracer .
|
-
-
- HY-118852R
-
|
|
Others
|
Others
|
|
Isoxaben (Standard) is the analytical standard of Isoxaben. This product is intended for research and analytical applications. Isoxaben, a herbicide, inhibits incorporation of radiolabeled glucose into an acid insoluble cell wall fraction. Isoxaben is also a specific inhibitor of cell wall biosynthesis .
|
-
-
- HY-N10791
-
|
|
Others
|
Infection
|
|
Neobritannilactone B, a sesquiterpene, can be isolated from the chloroform fraction of the I. britannica. Neobritannilactone B is cytotoxic. Other extracts of I. britannica are also Dihydrofolate reductase (DHFR) inhibitors, which inhibit Shigella dysenteriae type 1 .
|
-
-
- HY-N8254
-
|
|
Others
|
Others
|
|
Haginin A (compound 3）can be isolated from the EtOAc fraction of Lespedeza cyrtobotrya. Haginin A has radical scavenging activity with IC50 values of 9.0 μM and 37.7 μM in the ABTS system and DPPH system, respectively .
|
-
-
- HY-W127493
-
|
Ceryl Alcohol
|
Biochemical Assay Reagents
|
Infection
|
|
1-Hexacosanol is a compound in the bioactive fraction of plant extracts that mediates insecticidal activity. 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes aegypti and Chironomus riparius, exerting neurotoxic effects .
|
-
-
- HY-N0927
-
|
Tetrahydrocolumbamine; (S)-Tetrahydrocolumbamine
|
Dopamine Receptor
|
Others
|
|
(-)-Isocorypalmine (Tetrahydrocolumbamine), isolated from the crude base fraction of Corydalis chaerophylla, is a dopamine receptor ligand . Recombinant CYP719A21 displays strict substrate specificity and high affinity (Km=4.63 ± 0.71 μM) for (-)-Isocorypalmine .
|
-
-
- HY-116494
-
|
|
BCRP
|
Cancer
|
|
ML753286 is an orally active and selective BCRP (Breast cancer resistance protein) inhibitor with an IC50 of 0.6 μM. ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions, and is stable in plasma cross species .
|
-
-
- HY-162733
-
|
|
Others
|
Cardiovascular Disease
|
|
SVC-02 is a vasohibin (VASH) inhibitor with an IC50 value of 11 nM. SVC-02 reduces tubulin detyrosination. SVC-02 has the potential for the research of reduce myo-cardial stiffness and improve relaxation in Heart failure with preserved ejection fraction (HFpEF) .
|
-
-
- HY-N0786R
-
|
|
Others
|
Neurological Disease
|
|
Ginkgolide J (Standard) is the analytical standard of Ginkgolide J. This product is intended for research and analytical applications. Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC50 range of 12-54 μM, has neuroprotective and anti neuronal apoptotic ability .
|
-
-
- HY-118870
-
|
|
Endogenous Metabolite
|
Inflammation/Immunology
|
|
γ-Globulins from human blood are a class of proteins in the blood. γ-Globulin is a protein fraction of blood serum containing many antibodies that protect against bacterial and viral infectious diseases. γ-Globulins from human blood is used for common variable immunodeficiency
|
-
-
- HY-145581
-
|
AZD4831
|
Glutathione Peroxidase
|
Cardiovascular Disease
|
|
Mitiperstat (AZD4831) is an effective oral inhibitor of myeloperoxidase (MPO). Mitiperstat can reduce inflammation and improve microvascular function, and it can be used in studies related to heart failure, preserved or mildly reduced ejection fraction, non-alcoholic fatty liver disease, and chronic obstructive pulmonary disease .
|
-
-
- HY-N2852
-
|
|
Others
|
Others
|
|
α-Terthienylmethanol is a terthiophene isolated from the n-hexane fraction of E. prostrata. α-Terthienylmethanol has potent cytotoxic activity against human endometrial cancer cells (Hec1A and Ishikawa) (IC50 < 1 μM). α-Terthienylmethanol increases the intracellular level of ROS and decreases that of GSH .
|
-
-
- HY-100125
-
|
SR1368
|
COX
|
Inflammation/Immunology
|
|
Timegadine, a new antiinflammatory agent, is found to be a potent, competitive inhibitor of cyclo-oxygenase (COX) and lipo-oxygenase, with IC50s ranging from 5 nM (washed rabbit platelets) to 20 μM (rat brain) for COX and 100 μM for lipo-oxygenase both in the cytosol fraction of horse platelet homogenates, and in washed rabbit platelets.
|
-
-
- HY-P1428A
-
|
|
Neuropeptide Y Receptor
|
Cardiovascular Disease
|
|
RFRP-1(human) TFA is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume, ejection fraction and cardiac output, and increases plasma prolactin levels in rats.
|
-
-
- HY-N2203A
-
|
|
Others
|
Others
|
|
Vitexin2''-O-p-trans-coumarate is a flavonoid, can be isolated from the Et acetate-soluble fraction of the ethanolic extract of the seeds of Trigonella foenum-graecum. Vitexin2''-O-p-trans-coumarate strongly promotes 2BS cell proliferation induced by H2O2 .
|
-
- HY-163289
-
|
|
Others
|
Inflammation/Immunology
|
|
TSLP binder-1 (compound 46) is a bicyclic peptide, which binds to thymic stromal lymphopoietin (TSLP) at the site used by IL-7Rα subunit, shows high affinity for TSLP, with KD of 13 nM. TSLP binder-1 reveals good stability in rat plasma and rat lung S9 fraction .
|
-
- HY-N2018
-
|
α-D-Xylopyranose
|
Endogenous Metabolite
|
Metabolic Disease
|
|
α-D-Xylose (α-D-Xylopyranose) is a basic component of the five-carbon fraction of biomass and a precursor of hemicellulose. α-D-Xylose participates in a variety of enzyme-catalyzed reactions, which in turn participate in a variety of metabolic pathways. In addition, α-D-Xylose is also used in tanning, dyeing and as a diabetic food .
|
-
- HY-W102714R
-
|
|
Others
|
Metabolic Disease
|
|
1,2-Cyclohexylenedinitrilotetraacetic acid (Standard) is the analytical standard of 1,2-Cyclohexylenedinitrilotetraacetic acid. This product is intended for research and analytical applications. 1,2-Cyclohexylenedinitrilotetraacetic acid (CDTA) is a chelating agent. 1,2-Cyclohexylenedinitrilotetraacetic acid has an ability to remove manganese from brain and liver (in vivo) and their sub-cellular fractions (in vitro), of rats pretreated with manganese sulphate .
|
-
- HY-W127493R
-
|
|
Biochemical Assay Reagents
|
Infection
|
|
1-Hexacosanol (Standard) is the analytical standard of 1-Hexacosanol. This product is intended for research and analytical applications. 1-Hexacosanol is a compound in the bioactive fraction of plant extracts that mediates insecticidal activity. 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes aegypti and Chironomus riparius, exerting neurotoxic effects .
|
-
- HY-N2274
-
|
12-Oleanene-3β,16β,23,28-tetrol; 3β,16β-12-Oleanene-3, 16,23,28-tetrol
|
Others
|
Cancer
|
|
23-Hydroxylongispinogenin (12-Oleanene-3β,16β,23,28-tetrol) is extracted from Lysimachia heterogenea Klatt. Lysimachia heterogenea Klatt is a perennial herb, which is used as a folk medicine in subduing swelling and detoxicating in China. The effective fraction LH-1 of L. heterogene has antitumor activity .
|
-
- HY-125986
-
|
|
Phospholipase
|
Neurological Disease
|
GK187 is a potent and selective Group VIA calcium-independent phospholipase A2 (GVIA iPLA2) inhibitor with an XI(50) value of 0.0001. GK187 can be used for researching various neurological disorders .
[The XI(50) is the mole fraction of the inhibitor in the total substrate interface required to inhibit the enzyme by 50%.]
|
-
- HY-116494A
-
|
|
Others
|
Cancer
|
|
(6R)-ML753286 is an isomer of ML753286 (HY-116494). ML753286 is an orally active and selective BCRP (Breast cancer resistance protein) inhibitor with an IC50 of 0.6 μM. ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions, and is stable in plasma cross species .
|
-
- HY-131995
-
|
|
Cannabinoid Receptor
|
Metabolic Disease
|
|
O-Arachidonoyl glycidol (compound 1) is a 2-arachidonoylglycerol (2-AG) analog. O-Arachidonoyl glycidol inhibits cytosolic 2-oleoylglycerol (2-OG) hydrolysis with an IC50 value of 4.5 µM. O-Arachidonoyl glycidol blocks 2-OG hydrolysis in membrane fractions and anandamide hydrolysis with IC50s of 19, 12 µM, respectively .
|
-
- HY-N9300
-
|
|
Others
|
Inflammation/Immunology
|
|
1,6-Dihydro-4,7-epoxy-1-methoxy-3,4-methylenedioxy-6-oxo-3,8-lignan, a lignan derivative from the ethyl acetate soluble fraction of twigs of Magnolia denudate (Magnoliaceae), exhibits anti-platelet-activating factor (PAF) activity. PAF is a potent lipid mediator in inflammation and asthma .
|
-
- HY-N11526
-
|
|
Others
|
Inflammation/Immunology
|
|
3-Hydroxy-2-(palmitoyloxy)propyl stearat is a non-volatile compound. 3-Hydroxy-2-(palmitoyloxy)propyl stearat can be isolated from less polar fractions of the brown macroalga Fucus virsoides J. Agardh. This part of the substance has a good ability to scavenge free radicals and has a protective effect on the oxidative stress induced by hydrogen peroxide in zebrafish embryos .
|
-
- HY-W710399
-
|
DG(16:0/0:0/18:0); 1-Palmitin-3-Stearin
|
Endogenous Metabolite
|
Metabolic Disease
|
|
1-Palmitoyl-3-stearoyl-rac-glycerol is a diacylglycerol that contains palmitic acid (HY-N0830) at the sn-1 position and stearic acid (HY-B2219) at the sn-3 position. It has been found in palm-based diacylglycerols produced from palm stearin, palm mid fraction, palm oil, and palm olein, as well as in wheat bran and brewer’s spent grain extracts.
|
-
- HY-W011120R
-
|
|
Others
|
Metabolic Disease
|
|
Ethyl docosa-4,7,10,13,16,19-hexaenoate (Standard) is the analytical standard of Ethyl docosa-4,7,10,13,16,19-hexaenoate. This product is intended for research and analytical applications. Ethyl cis-4,7,10,13,16,19-Docosahexaenoate, the ethyl ester of Docosahexaenoate (DHA), is enriched in the ethyl ester fraction by the selective alcoholysis of fatty acid ethyl esters originating from tuna oil with lauryl alcohol.
|
-
- HY-W010667
-
|
1,3-Dipalmitoyl-2-oleoylglycerol; ?1,3-Palmitin-2-Olein; TG(16:0/18:1/16:0)
|
Endogenous Metabolite
|
Metabolic Disease
|
|
1,3-Dipalmitoyl-2-oleoyl glycerol (1,3-Palmitin-2-Olein; TG(16:0/18:1/16:0)) is a triacylglycerol that contains palmitic acid (HY-N0830) at the sn-1 and sn-3 positions and oleic acid (HY-N1446) at the sn-2 position. It has been found in cocoa butter, Chinese tallow butter, and the palm stearin fraction of palm oil.
|
-
- HY-131310
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
9(S)-HpOTrE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase (5-LO) on α-linolenic acid. It can be further metabolized to colnelenic acid by a divinyl ether synthase activity found in garlic and potato microsomal fractions. 9(S)-HpOTrE also serves as a substrate for further oxidation by both soybean and potato LOs, resulting in the formation of 9,16-dihydroperoxy acid.The suicide inactivation of LOs when 9(S)-HpOTrE is used as a substrate is thought to occur via formation of an unstable epoxide.
|
-
- HY-124187
-
|
Ethyl pinolenate
|
Biochemical Assay Reagents
|
Others
|
|
Pinolenic acid is a polyunsaturated fatty acid found in the seed oils of red pine (Pinus orientalis) and maritime pine (Pinus pinaster). Both oils were found to have lipid-lowering properties. A diet containing marine pine nut oil (MPSO) reduces HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to reduce cholesterol efflux in vitro. Korean pine nut oil supplements may help obesity by reducing appetite. People who take this oil experience an increase in the satiety hormones CCK and GLP-1 and a decrease in appetite. The activity of the oil is attributed to pinolenic acid. Pinolenic acid is not metabolized to arachidonic acid and can reduce the level of arachidonic acid in the phosphatidylinositol fraction of HepG2 cells from 15.9% to 7.0%. Pinolenic acid ethyl ester is a neutral, more lipophilic form of the free acid.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-138560
-
|
|
Filter Medium
|
|
Cross-linked dextran G 50 is a gel filtration medium. Cross-linked dextran G 50 can be used in gel permeation chromatography for fractionation of the glycopeptide mixture (Sphere protein separation range: 1.5K-30K Da; Polysaccharide separation range: 500-10K Da) .
|
-
- HY-W127493
-
|
Ceryl Alcohol
|
Cell Assay Reagents
|
|
1-Hexacosanol is a compound in the bioactive fraction of plant extracts that mediates insecticidal activity. 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes aegypti and Chironomus riparius, exerting neurotoxic effects .
|
-
- HY-124187
-
|
Ethyl pinolenate
|
Drug Delivery
|
|
Pinolenic acid is a polyunsaturated fatty acid found in the seed oils of red pine (Pinus orientalis) and maritime pine (Pinus pinaster). Both oils were found to have lipid-lowering properties. A diet containing marine pine nut oil (MPSO) reduces HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to reduce cholesterol efflux in vitro. Korean pine nut oil supplements may help obesity by reducing appetite. People who take this oil experience an increase in the satiety hormones CCK and GLP-1 and a decrease in appetite. The activity of the oil is attributed to pinolenic acid. Pinolenic acid is not metabolized to arachidonic acid and can reduce the level of arachidonic acid in the phosphatidylinositol fraction of HepG2 cells from 15.9% to 7.0%. Pinolenic acid ethyl ester is a neutral, more lipophilic form of the free acid.
|
-
- HY-W145695
-
|
|
Biochemical Assay Reagents
|
|
Chitoheptaose is a chitosan oligosaccharide. Chitoheptaose is capable of extracting exoskeletons from crustaceans, such as the shells of crabs, shrimp and lobsters. Chitoheptaose has antioxidant, anti-inflammatory and anti-apoptotic activities and can be used in the study of myocarditis. Chitoheptaose has cardioprotective effects and improves cardiac parameters (left ventricular internal size, end-systolic and end-diastolic, ejection fraction and shortening fraction), inflammatory cytokines (IL-1β) in vanishing models .
|
-
- HY-W127493R
-
|
|
Cell Assay Reagents
|
|
1-Hexacosanol (Standard) is the analytical standard of 1-Hexacosanol. This product is intended for research and analytical applications. 1-Hexacosanol is a compound in the bioactive fraction of plant extracts that mediates insecticidal activity. 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes aegypti and Chironomus riparius, exerting neurotoxic effects .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P1495
-
-
- HY-P5700
-
|
|
Bacterial
|
Infection
|
|
SAAP Fraction 3 is an antimicrobial peptide. SAAP Fraction 3 is active against P. haemolytica in Zn-saline buffer .
|
-
- HY-P1428A
-
|
|
Neuropeptide Y Receptor
|
Cardiovascular Disease
|
|
RFRP-1(human) TFA is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume, ejection fraction and cardiac output, and increases plasma prolactin levels in rats.
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-125361
-
-
-
- HY-N5073
-
-
-
- HY-N3621
-
-
-
- HY-N8977
-
-
-
- HY-P5700
-
-
-
- HY-N4245
-
-
-
- HY-N0860
-
-
-
- HY-N9379
-
-
-
- HY-N12039
-
-
-
- HY-N12352
-
-
-
- HY-B0399A
-
-
-
- HY-N3955
-
-
-
- HY-N11011
-
-
-
- HY-N0786
-
-
-
- HY-N12551
-
-
-
- HY-137295
-
-
-
- HY-N9900
-
-
-
- HY-121388
-
-
-
- HY-N3433
-
-
-
- HY-N10791
-
-
-
- HY-N8254
-
-
-
- HY-N0927
-
-
-
- HY-N0786R
-
-
-
- HY-118870
-
-
-
- HY-N2852
-
-
-
- HY-N2203A
-
-
-
- HY-N2018
-
-
-
- HY-N2274
-
|
12-Oleanene-3β,16β,23,28-tetrol; 3β,16β-12-Oleanene-3, 16,23,28-tetrol
|
Triterpenes
Structural Classification
Classification of Application Fields
Terpenoids
Source classification
Asclepiadaceae
Lysimachia heterogenea Klatt
Plants
Primulaceae
Disease Research Fields
Gymnema sylvestre (Retz.) Schult.
Cancer
|
Others
|
|
23-Hydroxylongispinogenin (12-Oleanene-3β,16β,23,28-tetrol) is extracted from Lysimachia heterogenea Klatt. Lysimachia heterogenea Klatt is a perennial herb, which is used as a folk medicine in subduing swelling and detoxicating in China. The effective fraction LH-1 of L. heterogene has antitumor activity .
|
-
-
- HY-N9300
-
-
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent:
