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fractionation

" in MedChemExpress (MCE) Product Catalog:

65

Inhibitors & Agonists

5

Biochemical Assay Reagents

3

Peptides

29

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-125361

    Others Others
    Ganosporeric acid A, a natural product, is isolated from the ether-soluble fraction of the spores of Ganoderma lucidum. Ganosporeric acid A can be used for the research of liver injury .
    Ganosporeric acid A
  • HY-138560
    Cross-linked dextran G 50
    1 Publications Verification

    Biochemical Assay Reagents Others
    Cross-linked dextran G 50 is a gel filtration medium. Cross-linked dextran G 50 can be used in gel permeation chromatography for fractionation of the glycopeptide mixture (Sphere protein separation range: 1.5K-30K Da; Polysaccharide separation range: 500-10K Da) .
    Cross-linked dextran G 50
  • HY-N3621

    Others Others
    Corchoionol C is a n-butanol-soluble fraction of the whole plant extract of Pulicaria undulate .
    Corchoionol C
  • HY-N8977

    Others Others
    4-O-Methylgrifolic acid is a farnesylphenols that can be isolated from the lipophilic fraction of Polyporus dispansus .
    4-O-Methylgrifolic acid
  • HY-160658

    CCR Inflammation/Immunology
    AZ760 is a CCR8 antagonist. AZ760 shows excellent potency, good lipophilicity and high free fraction in blood. AZ760 exhibits unacceptable hERG inhibition .
    AZ760
  • HY-157538

    PDHK Cardiovascular Disease
    PDK4-IN-2 (compound 8) is a pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 of 46 µM. PDK4-IN-2 improves ejection fraction of failing hearts by regulating bioenergetics via activation of the tricarboxylic acid cycle .
    PDK4-IN-2
  • HY-P5700

    Bacterial Infection
    SAAP Fraction 3 is an antimicrobial peptide. SAAP Fraction 3 is active against P. haemolytica in Zn-saline buffer .
    SAAP Fraction 3
  • HY-156980

    Others Infection
    Podilfen is an active fraction of Delftia strains 2189 .
    Podilfen
  • HY-N4245

    Others Others
    Siegesmethyletheric acid is isolated from the ethyl acetate fraction of Siegesbeckia orientalis L. (Asteraceae) .
    Siegesmethyletheric acid
  • HY-N0860

    Schizantherin-E

    Others Inflammation/Immunology
    Schisantherin E is a natural compound isolated from the active fraction of the fruits of Schisandra sphenanthera Rehd. et Wils.
    Schisantherin E
  • HY-N5073

    4''-O-Glucosylvitexin

    Others Cardiovascular Disease Metabolic Disease
    Vitexin-4''-O-glucoside is a kind of flavonoid fraction from the leaves of Crataegus pinnatifida .
    Vitexin-4''-O-glucoside
  • HY-N9379

    Others Others
    Fissistigine A is an alkaloid separated of the basic fractions from Formosan Fissistigma glaucescens, F. oldhamii and Goniothalamus amuyon .
    Fissistigine A
  • HY-N12039

    Others Others
    Juniper camphor is a sesquiterpene compound isolated from camphor blue oil, the high-boiling fraction of camphor .
    Juniper camphor
  • HY-N12352

    Others Others
    Eschweilenol C is a compound derivative ellagic acid from the aqueous fraction of the ethanolic extract of Terminalia fagifolia Mart. .
    Eschweilenol C
  • HY-116547

    4,5-Methylenephenanthrene

    Others Others
    Methylenephenanthrene (4,5-Methylenephenanthrene) can be isolated from the refined neutral fraction of anthracene oil
    Methylenephenanthrene
  • HY-B0399A

    (±)-Carnitin

    Mitochondrial Metabolism Metabolic Disease
    DL-Carnitine is a racemic mixture of L-Carnitine and D-Carnitine, regulates fatty acid transport in mitochondria, elevates serum carnitine fractions.
    DL-Carnitine
  • HY-N3955

    Glutinone; Glutinone

    Others Others
    Alnusenone (Glutinone) is a stabilised intermediate int he biogenesis of friedelin (XV) from squalene. Alnusenone is the major natural compound in fractions .
    Alnusenone
  • HY-118852

    Others Others
    Isoxaben, a herbicide, inhibits incorporation of radiolabeled glucose into an acid insoluble cell wall fraction. Isoxaben is also a specific inhibitor of cell wall biosynthesis .
    Isoxaben
  • HY-N11011

    Others Inflammation/Immunology
    Withaphysalin A is a withanolide-type compound. Withaphysalin A can be obtained from the anti-inflammatory fraction of P. minima. Withaphysalin A can be used for the research of inflammation .
    Withaphysalin A
  • HY-W145695

    Biochemical Assay Reagents Inflammation/Immunology
    Chitoheptaose is a chitosan oligosaccharide. Chitoheptaose is capable of extracting exoskeletons from crustaceans, such as the shells of crabs, shrimp and lobsters. Chitoheptaose has antioxidant, anti-inflammatory and anti-apoptotic activities and can be used in the study of myocarditis. Chitoheptaose has cardioprotective effects and improves cardiac parameters (left ventricular internal size, end-systolic and end-diastolic, ejection fraction and shortening fraction), inflammatory cytokines (IL-1β) in vanishing models .
    Chitoheptaose
  • HY-N0786

    Others Neurological Disease
    Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC50 range of 12-54 μM, has neuroprotective and anti neuronal apoptotic ability .
    Ginkgolide J
  • HY-133610

    Others Others
    3,4,6-trichlorocatechol (TCC) is the metabolite produced by industrial pollutant through post-mitochondrial liver fraction from Aroclor-1254 induced rats .
    3,4,6-Trichlorocatechol
  • HY-N12551

    Others Others
    2-O-β-D-Glucopyranosylcucurbitacin F 25-acetate is a cucurbitacin glucoside that can isolated from the more polar fractions of the MeOH extract of Cigarrilla mexicana .
    2-O-β-D-Glucopyranosylcucurbitacin F 25-acetate
  • HY-Y1422D

    Others Others
    Lipase 435, an immobilized lipase derived from Candida antarctica fraction B, shows extensive industrial application in producing enantiopure pharmaceuticals, functional lipids, biodiesel, etc. .
    Lipase 435
  • HY-112738

    Phospholipase Inflammation/Immunology
    AX048 is an inhibitor for calcium-dependent phospholipase A2 cPLA2 with a XI(50) of 0.022 mole fraction and reveals an antihyperalgesic efficacy .
    AX048
  • HY-137295

    PKC Apoptosis Inflammation/Immunology
    Ingenol 3,20-dibenzoate is a potent protein kinase C (PKC) isoform-selective agonist. Ingenol 3,20-dibenzoate induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the particulate fraction and induces morphologically typical apoptosis through de novo synthesis of macromolecules. Ingenol 3,20-dibenzoate increases the IFN-γ production and degranulation by NK cells, especially when NK cells are stimulated by NSCLC cells .
    Ingenol 3,20-dibenzoate
  • HY-N9900

    Demethyldaphnoretin-7-O-β-D-glucopyranoside

    Others Others
    Demethyldaphnoretin-7-O-β-Dglucopyranoside (Demethyldaphnoretin-7-O-glucoside)(compound 1) is a natural product isolated from the ethyl acetate fraction of the roots of Daphne oleoides .
    Demethyldaphnoretin-7-O-glucoside
  • HY-121388

    (+)-Ledol

    Fungal Infection
    Ledol ((+)-Ledol) is an antifungal agent that can be isolated from the essential oil fractions of Rhododendron tomentosum. Ledol is also the expectorant and antitussive agent, which is simultaneously responsible for adverse reactions such as dizziness, nausea and vomiting .
    Ledol
  • HY-W009934

    α-Phenyl-2-pyridineacetonitrile

    Drug Metabolite Endocrinology
    2-Phenyl-2-(2-pyridyl)acetonitrile is the major metabolite of SC 15396 metabolized by the supernatant fraction of rat liver homogenate. SC 15396 is an antigastrin that inhibits gastric secretion .
    2-Phenyl-2-(2-pyridyl)acetonitrile
  • HY-P1495

    Adenylate Cyclase Cardiovascular Disease Neurological Disease
    Small Cardioactive Peptide B (SCPB), a neurally active peptide, stimulates adenylate cyclase activity in particulate fractions of both heart and gill tissues with EC50s of 0.1 and 1.0 μM, respectively.
    Small Cardioactive Peptide B (SCPB)
  • HY-N3433
    Kaempferol 3-O-arabinoside
    1 Publications Verification

    Others Others
    Kaempferol 3-O-arabinoside is an antioxidant flavonoids isolated from ethyl acetate fraction (EAF) obtained from the leaves of Nectandra hihua. Kaempferol 3-O-arabinoside has good antioxidant capacity .
    Kaempferol 3-O-arabinoside
  • HY-N1014

    Others Others
    11α,12β-Di-O-acetyltenacigenin B is a polyoxypregnane compound isolated from the CHCl(3)-soluble fraction of the ethanolic extract of the stem of Marsdenia tenacissima .
    11α,12β-Di-O-acetyltenacigenin B
  • HY-W011120
    Ethyl docosa-4,7,10,13,16,19-hexaenoate
    1 Publications Verification

    Others Metabolic Disease
    Ethyl cis-4,7,10,13,16,19-Docosahexaenoate, the ethyl ester of Docosahexaenoate (DHA), is enriched in the ethyl ester fraction by the selective alcoholysis of fatty acid ethyl esters originating from tuna oil with lauryl alcohol.
    Ethyl docosa-4,7,10,13,16,19-hexaenoate
  • HY-153168

    Phosphodiesterase (PDE) Cardiovascular Disease
    Bemoradan (compound 10a) is an orally active and selective canine Phosphodiesterase (PDE) fraction III inhibitor. Bemoradan is a long-acting, potent, inotropic vasodilator and a novel cardiotonic agent, and can be used in congestive heart failure research .
    Bemoradan
  • HY-W102714

    CDTA

    Others Metabolic Disease
    1,2-Cyclohexylenedinitrilotetraacetic acid (CDTA) is a chelating agent. 1,2-Cyclohexylenedinitrilotetraacetic acid has an ability to remove manganese from brain and liver (in vivo) and their sub-cellular fractions (in vitro), of rats pretreated with manganese sulphate .
    1,2-Cyclohexylenedinitrilotetraacetic acid
  • HY-163079

    FAP Cancer
    AlF-PD-FAPI has affinity for FAP , with the IC50 of 0.13 nM, and shows a specific uptake, high internalized fraction, and low cellular efflux in vitro. AlF-PD-FAPI can be used as FAP-targeting tracer .
    AlF-PD-FAPI
  • HY-118852R

    Others Others
    Isoxaben (Standard) is the analytical standard of Isoxaben. This product is intended for research and analytical applications. Isoxaben, a herbicide, inhibits incorporation of radiolabeled glucose into an acid insoluble cell wall fraction. Isoxaben is also a specific inhibitor of cell wall biosynthesis .
    Isoxaben (Standard)
  • HY-N10791

    Others Infection
    Neobritannilactone B, a sesquiterpene, can be isolated from the chloroform fraction of the I. britannica. Neobritannilactone B is cytotoxic. Other extracts of I. britannica are also Dihydrofolate reductase (DHFR) inhibitors, which inhibit Shigella dysenteriae type 1 .
    Neobritannilactone B
  • HY-N8254

    Others Others
    Haginin A (compound 3)can be isolated from the EtOAc fraction of Lespedeza cyrtobotrya. Haginin A has radical scavenging activity with IC50 values of 9.0 μM and 37.7 μM in the ABTS system and DPPH system, respectively .
    Haginin A
  • HY-W127493

    Ceryl Alcohol

    Biochemical Assay Reagents Infection
    1-Hexacosanol is a compound in the bioactive fraction of plant extracts that mediates insecticidal activity. 1-Hexacosanol has larvicidal activity and can inhibit the acetylcholinesterase activity of Culex quinquefasciatus, Aedes aegypti and Chironomus riparius, exerting neurotoxic effects .
    1-Hexacosanol
  • HY-N0927

    Tetrahydrocolumbamine; (S)-Tetrahydrocolumbamine

    Dopamine Receptor Others
    (-)-Isocorypalmine (Tetrahydrocolumbamine), isolated from the crude base fraction of Corydalis chaerophylla, is a dopamine receptor ligand . Recombinant CYP719A21 displays strict substrate specificity and high affinity (Km=4.63 ± 0.71 μM) for (-)-Isocorypalmine .
    (-)-Isocorypalmine
  • HY-116494

    BCRP Cancer
    ML753286 is an orally active and selective BCRP (Breast cancer resistance protein) inhibitor with an IC50 of 0.6 μM. ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions, and is stable in plasma cross species .
    ML753286
  • HY-162733

    Others Cardiovascular Disease
    SVC-02 is a vasohibin (VASH) inhibitor with an IC50 value of 11 nM. SVC-02 reduces tubulin detyrosination. SVC-02 has the potential for the research of reduce myo-cardial stiffness and improve relaxation in Heart failure with preserved ejection fraction (HFpEF) .
    SVC-02
  • HY-N0786R

    Others Neurological Disease
    Ginkgolide J (Standard) is the analytical standard of Ginkgolide J. This product is intended for research and analytical applications. Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC50 range of 12-54 μM, has neuroprotective and anti neuronal apoptotic ability .
    Ginkgolide J (Standard)
  • HY-118870

    Endogenous Metabolite Inflammation/Immunology
    γ-Globulins from human blood are a class of proteins in the blood. γ-Globulin is a protein fraction of blood serum containing many antibodies that protect against bacterial and viral infectious diseases. γ-Globulins from human blood is used for common variable immunodeficiency
    γ-Globulins from human blood
  • HY-145581

    AZD4831

    Glutathione Peroxidase Cardiovascular Disease
    Mitiperstat (AZD4831) is an effective oral inhibitor of myeloperoxidase (MPO). Mitiperstat can reduce inflammation and improve microvascular function, and it can be used in studies related to heart failure, preserved or mildly reduced ejection fraction, non-alcoholic fatty liver disease, and chronic obstructive pulmonary disease .
    Mitiperstat
  • HY-N2852

    Others Others
    α-Terthienylmethanol is a terthiophene isolated from the n-hexane fraction of E. prostrata. α-Terthienylmethanol has potent cytotoxic activity against human endometrial cancer cells (Hec1A and Ishikawa) (IC50 < 1 μM). α-Terthienylmethanol increases the intracellular level of ROS and decreases that of GSH .
    α-Terthienylmethanol
  • HY-100125

    SR1368

    COX Inflammation/Immunology
    Timegadine, a new antiinflammatory agent, is found to be a potent, competitive inhibitor of cyclo-oxygenase (COX) and lipo-oxygenase, with IC50s ranging from 5 nM (washed rabbit platelets) to 20 μM (rat brain) for COX and 100 μM for lipo-oxygenase both in the cytosol fraction of horse platelet homogenates, and in washed rabbit platelets.
    Timegadine
  • HY-P1428A

    Neuropeptide Y Receptor Cardiovascular Disease
    RFRP-1(human) TFA is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume, ejection fraction and cardiac output, and increases plasma prolactin levels in rats.
    RFRP-1(human) TFA
  • HY-N2203A

    Others Others
    Vitexin2''-O-p-trans-coumarate is a flavonoid, can be isolated from the Et acetate-soluble fraction of the ethanolic extract of the seeds of Trigonella foenum-graecum. Vitexin2''-O-p-trans-coumarate strongly promotes 2BS cell proliferation induced by H2O2 .
    Vitexin2''-O-p-trans-coumarate

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