Ethyl docosa-4,7,10,13,16,19-hexaenoate

Name: Ethyl docosa-4,7,10,13,16,19-hexaenoate
Brand: MedChemExpress
SKU: HY-W011120
Rating: 4.5 (1 reviews)

Cat. No.: HY-W011120 Purity: ≥97.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Ethyl cis-4,7,10,13,16,19-Docosahexaenoate, the ethyl ester of Docosahexaenoate (DHA), is enriched in the ethyl ester fraction by the selective alcoholysis of fatty acid ethyl esters originating from tuna oil with lauryl alcohol.

For research use only. We do not sell to patients.

Ethyl docosa-4,7,10,13,16,19-hexaenoate Chemical Structure

CAS No. : 84494-72-4

Size	Price	Stock	Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 77	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 77	In-stock	Estimated Time of Arrival: December 31
Liquid
10 mg	USD 25	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 70	Get quote	Estimated Time of Arrival: December 31
100 mg		Get quote
200 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Ethyl docosa-4,7,10,13,16,19-hexaenoate:

Ethyl docosa-4,7,10,13,16,19-hexaenoate (Standard) Get quote

1 Publications Citing Use of MCE Ethyl docosa-4,7,10,13,16,19-hexaenoate

•Laurea Magistrale in Biomedical Engineering, Politecnico di Milano. 2019 Jun.

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Purity & Documentation
References
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Description

In Vitro

Ethyl cis-4,7,10,13,16,19-Docosahexaenoate (Ethyl docosahexaenoate; E-DHA) is efficiently enriched by the selective alcoholysis of ethyl esters originating from tuna oil with lauryl alcohol using immobilized lipase^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

356.55

Formula

C₂₄H₃₆O₂

CAS No.

84494-72-4

Appearance

Liquid (Density: 0.914±0.06 g/cm³)

Color

Colorless to light yellow

SMILES

CC/C=C/C/C=C/C/C=C/C/C=C/C/C=C/C/C=C/CCC(OCC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (280.47 mM; Need ultrasonic)

DMSO : 100 mg/mL (280.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.8047 mL	14.0233 mL	28.0466 mL
5 mM	0.5609 mL	2.8047 mL	5.6093 mL
10 mM	0.2805 mL	1.4023 mL	2.8047 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: 2.5 mg/mL (7.01 mM); Suspended solution; Need ultrasonic

This protocol yields a suspended solution of 2.5 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 2

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (7.01 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥97.0%

Select Batch:

Data Sheet (267 KB) SDS (252 KB)

COA (239 KB) HNMR (311 KB)

Handling Instructions (2659 KB)

References

[1]. Yuji Shimada, et al. Purification of ethyl docosahexaenoate by selective alcoholysis of fatty acid ethyl esters with immobilized Rhizomucor miehei lipase. J Am Oil Chem Soc. 1998 Nov, 75(11): 1565–1571.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / DMSO	1 mM	2.8047 mL	14.0233 mL	28.0466 mL	70.1164 mL
	5 mM	0.5609 mL	2.8047 mL	5.6093 mL	14.0233 mL
	10 mM	0.2805 mL	1.4023 mL	2.8047 mL	7.0116 mL
	15 mM	0.1870 mL	0.9349 mL	1.8698 mL	4.6744 mL
	20 mM	0.1402 mL	0.7012 mL	1.4023 mL	3.5058 mL
	25 mM	0.1122 mL	0.5609 mL	1.1219 mL	2.8047 mL
	30 mM	0.0935 mL	0.4674 mL	0.9349 mL	2.3372 mL
	40 mM	0.0701 mL	0.3506 mL	0.7012 mL	1.7529 mL
	50 mM	0.0561 mL	0.2805 mL	0.5609 mL	1.4023 mL
	60 mM	0.0467 mL	0.2337 mL	0.4674 mL	1.1686 mL
	80 mM	0.0351 mL	0.1753 mL	0.3506 mL	0.8765 mL
	100 mM	0.0280 mL	0.1402 mL	0.2805 mL	0.7012 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.