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glucuronic acid derivative

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By Targets:	Drug Derivative (1) Apoptosis (2) Endogenous Metabolite (3) Estrogen Receptor/ERR (1) Isotope-Labeled Compounds (1) Phosphodiesterase (PDE) (1) Toll-like Receptor (TLR) (2)
By Research Areas:	Cancer (3) Cardiovascular Disease (1) Inflammation/Immunology (3) Metabolic Disease (5)

7

Inhibitors & Agonists

4

Natural
Products

1

Isotope-Labeled Compounds

Targets Recommended: Drug Derivative Amino acid Transporter Amino Acid Derivatives Amino acid decarboxylase Hydroxycarboxylic Acid Receptor (HCAR) Free Fatty Acid Receptor Fatty Acid Synthase (FASN) Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

D-Glucuronic acid lactone D-Glucurono-6,3-lactone; D-Glucurono-γ-lactone; D-Glucuronolactone; Dicurone; Glucoxy; Glucurolactone; Glucurone	Endogenous Metabolite Drug Derivative	Cardiovascular Disease Metabolic Disease
D-Glucuronic acid lactone (D-Glucurono-6,3-lactone) is an endogenous metabolite, which is a glucuronic acid derivative. D-Glucuronic acid lactone can be used as starting regents in the synthesis of 2,3,4,-tris(tert.-butyldimethysilyl) glucuronic acid trichloroethylester, requirement for the preparation of 1-O-acyl glucuronide of the anti-inflammatory agent ML-3000 (HY-B1452), synthesis of optically active glucopyranoses, synthesis of long-chain alkyl glucofuranosides. D-Glucuronic acid lactone is promising for research of reversible cerebral vasoconstriction syndrome (RCVS) .

D-Glucuronic acid (Standard)	Endogenous Metabolite Toll-like Receptor (TLR)	Metabolic Disease Inflammation/Immunology Cancer
D-Glucuronic acid (Standard) is the analytical standard of D-Glucuronic acid. This product is intended for research and analytical applications. D-Glucuronic acid is a major component of many anti-inflammatory proteoglycans, which can promote embryonic development and inhibit cell aggregation. After being metabolized into ethyl glucuronide (HY-113093), D-Glucuronic acid activates Toll-like receptor 4 (TLR4), causing pain. D-Glucuronic acid and its derivative glucurono-lactone can serve as liver detoxifiers for human health prevention, and its derivatives also possess anti-tumor activity .

D-Glucuronic acid 1 Publications Verification	Endogenous Metabolite Toll-like Receptor (TLR)	Metabolic Disease Inflammation/Immunology Cancer
D-Glucuronic acid is a major component of many anti-inflammatory proteoglycans, which can promote embryonic development and inhibit cell aggregation. After being metabolized into ethyl glucuronide (HY-113093), D-Glucuronic acid activates Toll-like receptor 4 (TLR4), causing pain. D-Glucuronic acid and its derivative glucurono-lactone can serve as liver detoxifiers for human health prevention, and its derivatives also possess anti-tumor activity .

Beta-Zearalanol	Apoptosis	Metabolic Disease
Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells . Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid .

Isbufylline	Phosphodiesterase (PDE)	Inflammation/Immunology
Isbufylline is a Phosphodiesterase inhibitor. Isbufylline is orally available. Isbufylline can be used in the research of respiratory diseases and inflammation such as asthma and pneumonia.

Estradiol 3-(β-D-Glucuronide) (sodium)	Estrogen Receptor/ERR	Cancer
Estradiol 3-(β-D-Glucuronide) sodium is the glucuronic acid derivative of estradiol (HY-B0141). Estradiol 3-(β-D-Glucuronide) sodium is radiolabeled for use in tumor imaging and biodistribution studies .

β-Zearalanol-d4	Isotope-Labeled Compounds Apoptosis	Metabolic Disease
β-Zearalanol-d₄ is a deuterium labeled Beta-Zearalanol (HY-N6740） . Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells . Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid .

Cat. No.	Product Name	Category	Target	Chemical Structure

D-Glucuronic acid lactone D-Glucurono-6,3-lactone; D-Glucurono-γ-lactone; D-Glucuronolactone; Dicurone; Glucoxy; Glucurolactone; Glucurone	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Drug Derivative
D-Glucuronic acid lactone (D-Glucurono-6,3-lactone) is an endogenous metabolite, which is a glucuronic acid derivative. D-Glucuronic acid lactone can be used as starting regents in the synthesis of 2,3,4,-tris(tert.-butyldimethysilyl) glucuronic acid trichloroethylester, requirement for the preparation of 1-O-acyl glucuronide of the anti-inflammatory agent ML-3000 (HY-B1452), synthesis of optically active glucopyranoses, synthesis of long-chain alkyl glucofuranosides. D-Glucuronic acid lactone is promising for research of reversible cerebral vasoconstriction syndrome (RCVS) .

D-Glucuronic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite Toll-like Receptor (TLR)
D-Glucuronic acid (Standard) is the analytical standard of D-Glucuronic acid. This product is intended for research and analytical applications. D-Glucuronic acid is a major component of many anti-inflammatory proteoglycans, which can promote embryonic development and inhibit cell aggregation. After being metabolized into ethyl glucuronide (HY-113093), D-Glucuronic acid activates Toll-like receptor 4 (TLR4), causing pain. D-Glucuronic acid and its derivative glucurono-lactone can serve as liver detoxifiers for human health prevention, and its derivatives also possess anti-tumor activity .

D-Glucuronic acid 1 Publications Verification	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite Toll-like Receptor (TLR)
D-Glucuronic acid is a major component of many anti-inflammatory proteoglycans, which can promote embryonic development and inhibit cell aggregation. After being metabolized into ethyl glucuronide (HY-113093), D-Glucuronic acid activates Toll-like receptor 4 (TLR4), causing pain. D-Glucuronic acid and its derivative glucurono-lactone can serve as liver detoxifiers for human health prevention, and its derivatives also possess anti-tumor activity .

Beta-Zearalanol	Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Phenols Polyphenols Metabolic Disease Antibacterial Disease Research Disease Research Fields	Apoptosis
Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells . Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid .

Cat. No.	Product Name	Chemical Structure

β-Zearalanol-d4
β-Zearalanol-d₄ is a deuterium labeled Beta-Zearalanol (HY-N6740） . Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells . Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid .

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