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Results for "

miR-16

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (3) MicroRNA (23) Protein Arginine Deiminase (3)
By Research Areas:	Cancer (23) Inflammation/Immunology (3)
Oligonucleotides:	miRNA mimics (5) miRNA agomirs (5) miRNA antagomirs (5) MicroRNAs (20) miRNA inhibitors (5)

Inhibitors & Agonists

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-100574A

Cl-amidine hydrochloride Maximum Cited Publications 11 Publications Verification	Protein Arginine Deiminase Apoptosis MicroRNA	Inflammation/Immunology Cancer
Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor, with IC₅₀ values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively. Cl-amidine hydrochloride induces apoptosis in cancer cells. Cl-amidine hydrochloride induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine hydrochloride prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model .

HY-100574

Cl-amidine	Protein Arginine Deiminase Apoptosis MicroRNA	Inflammation/Immunology Cancer
Cl-amidine is an orally active peptidylarginine deminase (PAD) inhibitor, with IC₅₀ values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively. Cl-amidine induces apoptosis in cancer cells. Cl-amidine induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model .

HY-100574B

Cl-amidine TFA	Protein Arginine Deiminase Apoptosis MicroRNA	Inflammation/Immunology Cancer
Cl-amidine TFA is an orally active peptidylarginine deminase (PAD) inhibitor, with IC₅₀ values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively. Cl-amidine TFA induces apoptosis in cancer cells. Cl-amidine TFA induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine TFA prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model .

HY-R00324

*hsa-miR-16-5p mimic*	MicroRNA	Cancer
hsa-miR-16-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-16-5p mimic hsa-miR-16-5p mimic

HY-R04248

*rno-miR-16-3p mimic*	MicroRNA	Cancer
rno-miR-16-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

rno-miR-16-3p mimic rno-miR-16-3p mimic

HY-R00322

*hsa-miR-16-1-3p mimic*	MicroRNA	Cancer
hsa-miR-16-1-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-16-1-3p mimic hsa-miR-16-1-3p mimic

HY-R00323

*hsa-miR-16-2-3p mimic*	MicroRNA	Cancer
hsa-miR-16-2-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-16-2-3p mimic hsa-miR-16-2-3p mimic

HY-R02693

*mmu-miR-16-1-3p mimic*	MicroRNA	Cancer
mmu-miR-16-1-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-16-1-3p mimic mmu-miR-16-1-3p mimic

HY-RI00324

*hsa-miR-16-5p inhibitor*	MicroRNA	Cancer
hsa-miR-16-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-16-5p inhibitor hsa-miR-16-5p inhibitor

HY-RI04248

*rno-miR-16-3p inhibitor*	MicroRNA	Cancer
rno-miR-16-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

rno-miR-16-3p inhibitor rno-miR-16-3p inhibitor

HY-RI00322

*hsa-miR-16-1-3p inhibitor*	MicroRNA	Cancer
hsa-miR-16-1-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-16-1-3p inhibitor hsa-miR-16-1-3p inhibitor

HY-RI00323

*hsa-miR-16-2-3p inhibitor*	MicroRNA	Cancer
hsa-miR-16-2-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-16-2-3p inhibitor hsa-miR-16-2-3p inhibitor

HY-RI02693

*mmu-miR-16-1-3p inhibitor*	MicroRNA	Cancer
mmu-miR-16-1-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-16-1-3p inhibitor mmu-miR-16-1-3p inhibitor

HY-R00324A

*hsa-miR-16-5p agomir*	MicroRNA	Cancer
hsa-miR-16-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-16-5p agomir hsa-miR-16-5p agomir

HY-R04248A

*rno-miR-16-3p agomir*	MicroRNA	Cancer
rno-miR-16-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

rno-miR-16-3p agomir rno-miR-16-3p agomir

HY-R00322A

*hsa-miR-16-1-3p agomir*	MicroRNA	Cancer
hsa-miR-16-1-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-16-1-3p agomir hsa-miR-16-1-3p agomir

HY-R00323A

*hsa-miR-16-2-3p agomir*	MicroRNA	Cancer
hsa-miR-16-2-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-16-2-3p agomir hsa-miR-16-2-3p agomir

HY-R02693A

*mmu-miR-16-1-3p agomir*	MicroRNA	Cancer
mmu-miR-16-1-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-16-1-3p agomir mmu-miR-16-1-3p agomir

HY-RI00324A

*hsa-miR-16-5p antagomir*	MicroRNA	Cancer
hsa-miR-16-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-16-5p antagomir hsa-miR-16-5p antagomir

HY-RI04248A

*rno-miR-16-3p antagomir*	MicroRNA	Cancer
rno-miR-16-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

rno-miR-16-3p antagomir rno-miR-16-3p antagomir

HY-RI00322A

*hsa-miR-16-1-3p antagomir*	MicroRNA	Cancer
hsa-miR-16-1-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-16-1-3p antagomir hsa-miR-16-1-3p antagomir

HY-RI00323A

*hsa-miR-16-2-3p antagomir*	MicroRNA	Cancer
hsa-miR-16-2-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-16-2-3p antagomir hsa-miR-16-2-3p antagomir

HY-RI02693A

*mmu-miR-16-1-3p antagomir*	MicroRNA	Cancer
mmu-miR-16-1-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-16-1-3p antagomir mmu-miR-16-1-3p antagomir

Cat. No.	Product Name		Classification