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Results for "

radiopharmaceutical

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (6)
By Research Areas:	Cancer (5) Cardiovascular Disease (1) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W102590

DOTMP	Biochemical Assay Reagents	Others
DOTMP is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .

HY-129650

Flobetapir 1 Publications Verification AV-45	Others	Others
Flobetapir (AV-45) may be a well-tolerated imaging agent. Flobetapir synthesizes Florbetapir (18F) that is a PET scanning radiopharmaceutical compound containing the radionuclide fluorine-18 .

HY-160131

Macropa	Others	Cancer
Macropa is a macrocyclic chelator that can be used as radionuclides to study soft tissue metastases .

HY-129040A

Iobenguane sulfate 1 Publications Verification MIBG sulfate	Others	Cancer
Iobenguane sulfate (MIBG sulfate) is an analogue of the neurotransmitter norepinephrine with antitumor activity. Radioiodinated Iobenguane sulfate is clinically used as a tumor-targeted radiopharmaceutical in the diagnosis and treatment of adrenergic tumors. Iobenguane sulfate is a high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation) .

HY-B1684

Mebrofenin SQ 26962	Biochemical Assay Reagents	Others
Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA). Mebrofenin is available as a ready to use the kit for radio-labeling with Tc-99m. Tc-99m Mebrofenin, a diagnostic agent, is used for hepatobiliary imaging. Tc-99m Mebrofenin is the radiopharmaceutical of choice for the evaluation of hepatic function .

HY-W143890

Etifenin EHIDA	Biochemical Assay Reagents	Neurological Disease Metabolic Disease
Etifenin can be used for production of non-toxic radiopharmaceuticals which are in regular radiodiagnostic use .

HY-W004649

Tris-BOC-cyclen	Biochemical Assay Reagents	Others
Tris-BOC-cyclen is a bifunctional chelator. Bifunctional chelating agentscan be used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .

HY-W402032

Bis-Cbz-cyclen	Biochemical Assay Reagents	Others
Bis-Cbz-cyclen is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .

HY-163925

Lu-AAZTA-NI-PSMA-093	Others	Cancer
Lu-AAZTA-NI-PSMA-093 is a bivalent radiopharmaceutical agent for prostate cancer, that enhances tumor uptake and retention by combining a hypoxia-sensitive nitroimidazole (NI) moiety with a targeting moiety to PSMA .

HY-W109978

Tetrabutylammonium perrhenate	Biochemical Assay Reagents	Others
Tetrabutylammonium perrhenate is a quaternary ammonium salt belonging to the class of alkylammonium salts. This compound is used as a catalyst in organic synthesis, especially in the production of alkenes and alcohols. Furthermore, due to its ability to bind radioisotopes, it is useful as a radiopharmaceutical in nuclear medicine. Its unique chemical properties make it an essential ingredient in a variety of industrial processes, including petrochemical refining and pharmaceuticals.

HY-129040AR

Iobenguane sulfate (Standard)	Others	Cancer
Iobenguane (sulfate) (Standard) is the analytical standard of Iobenguane (sulfate). This product is intended for research and analytical applications. Iobenguane sulfate (MIBG sulfate) is an analogue of the neurotransmitter norepinephrine with antitumor activity. Radioiodinated Iobenguane sulfate is clinically used as a tumor-targeted radiopharmaceutical in the diagnosis and treatment of adrenergic tumors. Iobenguane sulfate is a high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation) .

HY-121659

DCFBC	Others	Cancer
DCFBC is a prostate-specific membrane antigen (PSMA) inhibitor for small animal positron emission tomography (PET) imaging. [18F]DCFBC was prepared by reacting fluorine-18 labeled phenyl bromide with the precursor (S)-2-[3-[(R)-1-carboxy-2-thiolethyl]urea]-glutaric acid in ammonia-saturated methanol at 60°C for 10 min and then purified by C-18 reversed-phase HPLC. [18F]DCFBC was injected via the tail vein in severe combined immunodeficient mice for in vitro biodistribution or imaging. For in vitro biodistribution studies, mice were sacrificed at 5, 15, 30, 60, and 120 min after injection, and tumors, blood, and major organs were collected, weighed, and radioactivity was counted. Imaging was performed using a GE eXploreVista small animal PET scanner, collecting 12 consecutive 10-min frames. Results showed that the radiochemical yield of [18F]DCFBC averaged 16±6% (n=8) from 4-[18F]fluorophenyl bromide. Specific radioactivity ranged from 13 to 133 GBq/Amol (350-3600 Curie/mmol) with an average of 52 GBq/Amol (1392 Curie/mmol; n=6). Biodistribution and imaging studies showed high uptake of [18F]DCFBC in PIP tumors and almost no uptake in FLU tumors. High radiopharmaceutical uptake was also seen in the kidney and bladder; however, radioactivity washout from these organs was faster than from the PIP tumors. Maximum PIP tumor uptake was reached at 60 min post-injection at 8.16±2.55% injected dose/g and decreased to 4.69±0.89 at 120 min post-injection. The PIP tumor-to-muscle ratio was 20 at 120 min post-injection. Based on mouse biodistribution, the dose-limiting organ was the kidney (estimated human absorbed dose: 0.05 mGy/MBq; 0.2 rad/mCi). Conclusions: [18F]DCFBC localizes specifically to PSMA+ expressing tumors in mice and is suitable for small animal PET imaging. This novel radiopharmaceutical is an attractive candidate for further study in PET imaging of prostate cancer.

Cat. No.	Product Name	Type

HY-W102590

DOTMP	Chelators
DOTMP is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .

HY-B1684

Mebrofenin SQ 26962	Indicators
Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA). Mebrofenin is available as a ready to use the kit for radio-labeling with Tc-99m. Tc-99m Mebrofenin, a diagnostic agent, is used for hepatobiliary imaging. Tc-99m Mebrofenin is the radiopharmaceutical of choice for the evaluation of hepatic function .

HY-W004649

Tris-BOC-cyclen	Chelators
Tris-BOC-cyclen is a bifunctional chelator. Bifunctional chelating agentscan be used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .

HY-W402032

Bis-Cbz-cyclen	Chelators
Bis-Cbz-cyclen is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical .

HY-W109978

Tetrabutylammonium perrhenate	Biochemical Assay Reagents
Tetrabutylammonium perrhenate is a quaternary ammonium salt belonging to the class of alkylammonium salts. This compound is used as a catalyst in organic synthesis, especially in the production of alkenes and alcohols. Furthermore, due to its ability to bind radioisotopes, it is useful as a radiopharmaceutical in nuclear medicine. Its unique chemical properties make it an essential ingredient in a variety of industrial processes, including petrochemical refining and pharmaceuticals.

Tetrabutylammonium perrhenate

Biochemical Assay Reagents

Tetrabutylammonium perrhenate is a quaternary ammonium salt belonging to the class of alkylammonium salts. This compound is used as a catalyst in organic synthesis, especially in the production of alkenes and alcohols. Furthermore, due to its ability to bind radioisotopes, it is useful as a radiopharmaceutical in nuclear medicine. Its unique chemical properties make it an essential ingredient in a variety of industrial processes, including petrochemical refining and pharmaceuticals.

Cat. No.	Product Name	Target	Research Area

HY-P10369

Betiatide	Peptides	Cardiovascular Disease Inflammation/Immunology
Betiatide, as a chelating agent for Technetium-99m ( ^99mTc), is used to prepare ^99mTc-MAG3 (mercaptoacetyltriglycine), a radiopharmaceutical for renal function imaging. Betiatide is used for the diagnosis of congenital and acquired abnormalities, renal failure, urinary tract obstructions, and calculi .

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