1. Antibody-drug Conjugate/ADC Related
  2. Radionuclide-Drug Conjugates (RDCs)
  3. Betiatide

Betiatide, as a chelating agent for Technetium-99m (99mTc), is used to prepare 99mTc-MAG3 (mercaptoacetyltriglycine), a radiopharmaceutical for renal function imaging. Betiatide is used for the diagnosis of congenital and acquired abnormalities, renal failure, urinary tract obstructions, and calculi.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Betiatide Chemical Structure

Betiatide Chemical Structure

CAS No. : 103725-47-9

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Description

Betiatide, as a chelating agent for Technetium-99m (99mTc), is used to prepare 99mTc-MAG3 (mercaptoacetyltriglycine), a radiopharmaceutical for renal function imaging. Betiatide is used for the diagnosis of congenital and acquired abnormalities, renal failure, urinary tract obstructions, and calculi[1].

Molecular Weight

367.38

Formula

C15H17N3O6S

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

{Bzsac}-Gly-Gly-Gly

Sequence Shortening

{Bzsac}-GGG

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 16.67 mg/mL (45.38 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7220 mL 13.6099 mL 27.2198 mL
5 mM 0.5444 mL 2.7220 mL 5.4440 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7220 mL 13.6099 mL 27.2198 mL 68.0494 mL
5 mM 0.5444 mL 2.7220 mL 5.4440 mL 13.6099 mL
10 mM 0.2722 mL 1.3610 mL 2.7220 mL 6.8049 mL
15 mM 0.1815 mL 0.9073 mL 1.8147 mL 4.5366 mL
20 mM 0.1361 mL 0.6805 mL 1.3610 mL 3.4025 mL
25 mM 0.1089 mL 0.5444 mL 1.0888 mL 2.7220 mL
30 mM 0.0907 mL 0.4537 mL 0.9073 mL 2.2683 mL
40 mM 0.0680 mL 0.3402 mL 0.6805 mL 1.7012 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Betiatide
Cat. No.:
HY-P10369
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