From 11:00 pm to 12:00 pm EST ( 8:00 pm to 9:00 pm PST ) on January 6th, the website will be under maintenance. We are sorry for the inconvenience. Please arrange your schedule properly.
RNase B, Bovine Pancreas is an N-glycosylated form of bovine pancreatic ribonuclease, which is structurally analogous to RNase A. RNase B, Bovine Pancreas promotes the folding of polypeptide chains and performs a chaperone-like function .
RNase A, bovine pancreas (Ribonuclease A) cleaves the 3' end of RNA to pyrimidine and actively cleaves RNA at each pyrimidine residue. RNase A, bovine pancreas catalyzes the hydrolysis of single-stranded RNA in the absence of metal ions or cofactors .
Caf1-IN-1 (Compound 8j) is inhibitor for ribonucleaseCaf1 with an IC50 of 0.59 µM. Caf1-IN-1 is also a weak inhibitor for poly(A)-specific ribonuclease (PARN) with IC50 of 23.9 µM .
RNase A, Recombinant (Ribonuclease A, Recombinant) is an endonuclease that specifically hydrolyzes cytosine or uracil residues in RNA for DNA purification .
RNase A, Bovine Pancreas (Ribonuclease A) (DNase & Protease Free) is a ribonuclease, a widely used endonuclease that acts by specifically hydrolyzing cytosine or uracil residues in RNA. RNase A, Bovine Pancreas (DNase & Protease Free) is commonly used in cell cycle assays .
Ribonuclease T2, Aspergillus oryzae is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible .
RNase A (DNase & Protease Free), Recombinant is an endonuclease, that can be found in bovine pancreas. RNase A (DNase & Protease Free), Recombinant purifies DNA by hydrolyzing cytosine or uracil residues in RNA. RNase A (DNase & Protease Free), Recombinant regulates cell growth, proliferation, differentiation, and migration, and exhibits antitumor efficacy .
GSK5750 is a specific and potent HIV-1 reverse transcriptase ribonuclease H inhibitor with an IC50 value of 0.33 μM. GSK5750 is bound at the RNase H active site through a metalion chelation mechanism .
CI-39 is an antiviral natural product. CI-39 is an NNRTI (non-nucleoside reverse transcriptase inhibit) antiviral agent with an EC50 of 3.40 µM and an CC50 of >30 µM for wild type HIV-1. CI-39 inhibits HIV-1 RT DNA polymerase and ribonuclease H activitiessup .
Ribonulease T1, Aspergillus oryzae (Rnase T1), is commonly used in biochemical research. Ribonuclease T1 is an endonuclease that can specifically degrade single stranded RNA. Ribonuclease T1 can form nucleoside 2 ', 3 '-cyclic phosphoric acid intermediates to cut the phosphodiester bond between 3' -guanosine residues and adjacent nucleoside 5 '-OH groups to produce 3' -GMP terminal oligonucleotides .
Sennoside A is an anthraquinone glycoside found in senna (Cassia angustifolia). Sennoside A is an HIV-1 inhibitor (IC50=3.8 μM) that inhibits HIV-1 replication. Sennoside A also inhibits HIV-1 reverse transcriptase (RT)-related DNA polymerase (RDDP) and ribonuclease H (Ribonuclease H) with IC50s of 1.9 μM and 5.3 μM, respectively .
RNase L-IN-1 (compound 17a) is an inhibitor of RNase L, or Ribonuclease L. RNase L degrades RNAs to prevent viral replication, and mediates the innate immune responses and inflammation .
Hydroxystilbamidine, a dye capable of binding to both DNA and RNA, is a powerful inhibitor of cellular ribonucleases. Hydroxystilbamidine is a retrograde fluorescent tracer and a histochemical stain [1]
RNase L-IN-1 (compound 17a) trihydrochloride is an inhibitor of RNase L or ribonuclease L. RNase L degrades RNA to prevent viral replication and mediates innate immune responses and inflammation .
RNase A (10mg/mL, DNase free) is a ribonuclease used to catalyze RNA degradation without containing DNase. RNase A is often employed in cell cycle assay .
Hydroxystilbamidine bis(methanesulfonate) is a dye that can bind to DNA and RNA; it's a fluorescent cationic dye, often used as a retrograde neuronal tracer and has also been found to be a potent inhibitor of cellular ribonucleases.
β-Thujaplicinol (3-Hydroxy-5-isopropyltropolone) is an inhibitor of hepatitis B virus (HBV) ribonuclease H. β-Thujaplicinol inhibits RNAseHs of HBV genotypes D and H with IC50 values of 5.9 and 2.3 μM, respectively .
HIV-1 integrase inhibitor 9 (compound 8a) is a potent HIV-1 RNase H inhibitor with an IC50 of 12.3 μM. HIV-1 integrase inhibitor 9 shows an antiviral activity .
Hydroxyisoquinoline-1,3(2H,4H)-dione (compound 6a) is a HIV-1 integrase (IN) and HIV-1 reverse transcriptase (RT) ribonuclease H (RNase H) inhibitor with an IC50 value of 6.32, 5.9 µM, respectively .
MYC-RIBOTAC is a ribonuclease-targeting chimera (RIBOTAC) to MYC internal ribosome entry site (IRES).MYC-RIBOTAC contains a MYC mRNA-binder and a small molecule that recruits and locally activates RNase L1 and decreases the mRNA and protein expression levels of MYC, induces apoptosis. MYC-RIBOTAC can be used for anticancer research .
2'-RIBOTAC-U is a ribonuclease (RNase) targeting chimeras (RIBOTACs) and SARS-CoV-2 replication inhibitor. 2'-RIBOTAC-U is composed of a metabolic
handle (Blue), a linker (Black) and a
RNase L recruiter (Pink). RIBOTACs recruits cellular RNases to specific RNA targets, thereby leading to the degradation of these RNAs .
BCH001, a quinoline derivative, is a specific PAPD5 inhibitor. BCH001 restores telomerase activity and telomere length in dyskeratosis congenita (DC) induced pluripotent stem cells. BCH001 shows no inhibition of poly(A)-specific ribonuclease (PARN) or several other canonical and non-canonical polynucleotide polymerases. BCH001 is used to regulate aging .
NSC727447 is an inhibitor of ribonuclease H (Rnase H) of HIV-1 and HIV-2. NSC727447 has little activity against E. coli RNase H, but great selectivity over human Rnase H, with IC50s value of 2.0 μM, 2.5 μM, 100 μM, 10.6 μM, respectively .
Hydroxystilbamidine bis(methanesulfonate) is a dye that can bind to DNA and RNA; it's a fluorescent cationic dye, often used as a retrograde neuronal tracer and has also been found to be a potent inhibitor of cellular ribonucleases.
Sennoside A is an anthraquinone glycoside found in senna (Cassia angustifolia). Sennoside A is an HIV-1 inhibitor (IC50=3.8 μM) that inhibits HIV-1 replication. Sennoside A also inhibits HIV-1 reverse transcriptase (RT)-related DNA polymerase (RDDP) and ribonuclease H (Ribonuclease H) with IC50s of 1.9 μM and 5.3 μM, respectively .
β-Thujaplicinol (3-Hydroxy-5-isopropyltropolone) is an inhibitor of hepatitis B virus (HBV) ribonuclease H. β-Thujaplicinol inhibits RNAseHs of HBV genotypes D and H with IC50 values of 5.9 and 2.3 μM, respectively .
Ribonuclease J/RnJ Proteinas, an enzyme with 5'-3' exonuclease activity and potential endonuclease function, is crucial in ribosomal RNA (rRNA) maturation. It also plays a role in mRNA maturation/decay, contributing to intricate RNA processing, ensuring precise maturation, and quality control in the cellular environment. Ribonuclease J/RnJ Protein, Synechocystis sp. (His-SUMO) is the recombinant Ribonuclease J/RnJ protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
Ribonuclease R (RNase R) is a 3'-5' exoribonuclease crucial for structured RNA maturation, degrading rRNAs, tRNAs, and SsrA/tmRNA. It modulates ompA mRNA stability in the stationary phase, exhibiting processive activity and helicase function. RNase R, along with PNPase, ensures rRNA quality during steady-state growth and contributes to virulence gene expression in E. coli. Ribonuclease R (rnr) protein, E.coli (His) is the recombinant E. coli-derived Ribonuclease R, expressed by E. coli , with N-6*His labeled tag. The total length of Ribonuclease R (rnr) protein, E.coli (His) is 813 a.a., with molecular weight of ~90 kDa.
The ribonuclease UK114/HRSP12 protein catalyzes the hydrolytic deamination of enamine/imine intermediates, reducing the potential toxicity of these reactive metabolites by releasing ammonia. Ribonuclease UK114/HRSP12 Protein, Human (His) is the recombinant human-derived Ribonuclease UK114/HRSP12 protein, expressed by E. coli , with N-6*His labeled tag. The total length of Ribonuclease UK114/HRSP12 Protein, Human (His) is 137 a.a., with molecular weight of 14-16 kDa.
The RNASET2 protein is a ribonuclease that makes a crucial contribution to the innate immune response by degrading microbial RNA sensed by TLR8. It preferentially cleaves single-stranded RNA, generating products that promote RNA-dependent TLR8 activation. RNASET2 Protein, Human (sf9, His) is the recombinant human-derived RNASET2 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of RNASET2 Protein, Human (sf9, His) is 232 a.a., with molecular weight of ~35 kDa.
The RNASET2 protein is a ribonuclease that makes a crucial contribution to the innate immune response by degrading microbial RNA sensed by TLR8. It preferentially cleaves single-stranded RNA, generating products that promote RNA-dependent TLR8 activation. RNASET2 Protein, Human (HEK293, His) is the recombinant human-derived RNASET2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of RNASET2 Protein, Human (HEK293, His) is 232 a.a., with molecular weight of 38-45 kDa.
The RNase 1 protein functions as an endonuclease capable of catalyzing RNA cleavage specific to the 3' side of pyrimidine nucleotides. This enzymatic activity extends to single- and double-stranded RNA, demonstrating its versatility in RNA substrate recognition and processing. Rnase 1 Protein, Human (HEK293, His) is the recombinant human-derived Rnase 1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Rnase 1 Protein, Human (HEK293, His) is 128 a.a., with molecular weight of 21-28 kDa.
Rnase 3 Protein, Human (HEK293, His) is the recombinant human-derived Rnase 3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Rnase 3 Protein, Human (HEK293, His) is 133 a.a., with molecular weight of 25-35 kDa.
The RNase 1 protein functions as an endonuclease capable of catalyzing RNA cleavage specific to the 3' side of pyrimidine nucleotides. This enzymatic activity extends to single- and double-stranded RNA, demonstrating its versatility in RNA substrate recognition and processing. Rnase 1 Protein, Human (HEK293, His, solution) is the recombinant human-derived Rnase 1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Rnase 1 Protein, Human (HEK293, His, solution) is 128 a.a., with molecular weight of 18-28 kDa.
RNASE6 Protein, a pyrimidine-preferring ribonuclease, exhibits potent antibacterial activity against diverse bacteria, including P. aeruginosa, A. baumanii, and E. coli. Its effect is independent of ribonuclease activity, inducing bacterial membrane disruption and Gram-negative bacteria agglutination, emphasizing its bactericidal properties. RNASE6's robust antibacterial activity suggests a potential role in preserving urinary tract sterility. RNASE6 Protein, Human (HEK293, His) is the recombinant human-derived RNASE6 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of RNASE6 Protein, Human (HEK293, His) is 127 a.a., with molecular weight of ~22.0 kDa.
RNase L Antibody (YA2314) is a biotin-conjugated non-conjugated IgG antibody, targeting RNase L, with a predicted molecular weight of 84 kDa (observed band size: 80 kDa). RNase L Antibody (YA2314) can be used for WB experiment in human background.
Product Comparison
Compare
Clear All
Compare Products
Products
In-stock
-
+
Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample
YesNo
Size
* This product has been "discontinued".
Optimized version of product available:
/
In-stock
-
+
Add to Cart
Get quote
Inquiry Online
Your information is safe with us. * Required Fields.
