2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. 3β-Hydroxy-lup-20(29)-en-16-one

3β-Hydroxy-lup-20(29)-en-16-one (compound 9) is a dual inhibitor of AChE and BChE, with selectivity for BChE (IC50: 28.9 μM).

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3β-Hydroxy-lup-20(29)-en-16-one Chemical Structure

3β-Hydroxy-lup-20(29)-en-16-one Chemical Structure

CAS No. : 65043-60-9

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3β-Hydroxy-lup-20(29)-en-16-one Related Antibodies

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Description

3β-Hydroxy-lup-20(29)-en-16-one (compound 9) is a dual inhibitor of AChE and BChE, with selectivity for BChE (IC50: 28.9 μM)[1].

IC50 & Target

IC50: 28.9 μM (BChE)[1]
Molecular Weight

440.70

Formula

C30H48O2
CAS No.
SMILES

C[C@]12[C@]3([C@@](CC[C@]1([H])[C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])CC2)C)([H])[C@]5([H])[C@@](C(C3)=O)(CC[C@H]5C(C)=C)C)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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3β-Hydroxy-lup-20(29)-en-16-one Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3β-Hydroxy-lup-20(29)-en-16-one65043-60-9Cholinesterase (ChE)Cholinesterase inhibitorsLupane derivativesMolecular modelingTriterpenoidInhibitorinhibitorinhibit

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