2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 5'-Guanylic acid disodium salt

5'-Guanylic acid disodium salt  (Synonyms: 5'-GMP disodium salt; 5'-guanosine monophosphate disodium salt)

Cat. No.: HY-W010970 Purity: ≥98.0%
COA Handling Instructions

Molarity Calculator

5'-Guanylic acid disodium salt (5'-GMP disodium salt) is composed of guanine, ribose, and phosphate moieties and it is a nucleotide monomer in messenger RNA. Guanosine derivatives are involved in intracellular signal transduction and have been identified in repetitive genomic sequences in telomeres, in ribosomal DNA, immunoglobulin heavy‐chain switch regions, and in the control regions of proto-oncogenes.

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5'-Guanylic acid disodium salt Chemical Structure

5'-Guanylic acid disodium salt Chemical Structure

CAS No. : 5550-12-9

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 USD 55 In-stock
Solution
10 mM * 1 mL in Water USD 55 In-stock
Solid
100 mg USD 50 In-stock
1 g USD 70 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of 5'-Guanylic acid disodium salt:

5'-Guanylic acid disodium salt Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE 5'-Guanylic acid disodium salt

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

5'-Guanylic acid disodium salt (5'-GMP disodium salt) is composed of guanine, ribose, and phosphate moieties and it is a nucleotide monomer in messenger RNA. Guanosine derivatives are involved in intracellular signal transduction and have been identified in repetitive genomic sequences in telomeres, in ribosomal DNA, immunoglobulin heavy‐chain switch regions, and in the control regions of proto-oncogenes[1].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

407.18

Formula

C10H12N5Na2O8P
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=P(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC3=C2N=C(N)NC3=O)O1)(O[Na])O[Na]
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (122.80 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4559 mL 12.2796 mL 24.5592 mL
5 mM 0.4912 mL 2.4559 mL 4.9118 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 50 mg/mL (122.80 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (251 KB) HNMR (248 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.4559 mL 12.2796 mL 24.5592 mL 61.3979 mL
5 mM 0.4912 mL 2.4559 mL 4.9118 mL 12.2796 mL
10 mM 0.2456 mL 1.2280 mL 2.4559 mL 6.1398 mL
15 mM 0.1637 mL 0.8186 mL 1.6373 mL 4.0932 mL
20 mM 0.1228 mL 0.6140 mL 1.2280 mL 3.0699 mL
25 mM 0.0982 mL 0.4912 mL 0.9824 mL 2.4559 mL
30 mM 0.0819 mL 0.4093 mL 0.8186 mL 2.0466 mL
40 mM 0.0614 mL 0.3070 mL 0.6140 mL 1.5349 mL
50 mM 0.0491 mL 0.2456 mL 0.4912 mL 1.2280 mL
60 mM 0.0409 mL 0.2047 mL 0.4093 mL 1.0233 mL
80 mM 0.0307 mL 0.1535 mL 0.3070 mL 0.7675 mL
100 mM 0.0246 mL 0.1228 mL 0.2456 mL 0.6140 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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5'-Guanylic acid disodium salt Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5'-Guanylic acid disodium5550-12-95'-GMP disodium5'-guanosine monophosphate disodiumEndogenous MetaboliteInhibitorinhibitorinhibit

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