Cy5-Paclitaxel

Cat. No.: HY-D2422B: FAQs
Data Sheet Handling Instructions

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Cy5-Paclitaxel is a CY5 (HY-D0821) labeled Paclitaxel (HY-B0015) conjugate. Cy5 is a Cyanine dye (with a long wavelength about 662nm) that can be used for molecular labeling and microscopy imaging. Paclitaxel stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy.

For research use only. We do not sell to patients.

Cy5-Paclitaxel Chemical Structure

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Description	Cy5-Paclitaxel is a CY5 (HY-D0821) labeled Paclitaxel (HY-B0015) conjugate. Cy5 is a Cyanine dye (with a long wavelength about 662nm) that can be used for molecular labeling and microscopy imaging. Paclitaxel stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Paclitaxel also induces autophagy^[1].
Molecular Weight	1533.84
Formula	C₉₃H₁₀₄N₄O₁₆⁺
SMILES	CC1(C)C2=C3C(C=CC=C3)=CC=C2[N+](C)C1/C=C/C=C/C=C4C(C)(C)C5=C(C=CC=C6)C6=CC=C5N\4CCCCCC(NCCCCCC(O[C@@H](C(O[C@H]7C[C@@]([C@H]([C@]([C@](C([C@@H]8OC(C)=O)=O)([C@H]9O)C)([H])[C@]%10([C@@H](C9)OC%10)OC(C)=O)OC(C%11=CC=CC=C%11)=O)(C(C)(C8=C7C)C)O)=O)[C@@H](NC(C%12=CC=CC=C%12)=O)C%13=CC=CC=C%13)=O)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (268 KB) Handling Instructions (2659 KB)
References	[1]. Xu C, et al. Photo-controlled release of paclitaxel and model drugs from RNA pyramids. Nano Res. 2019 Jan;12(1):41-48. [Content Brief]

Cy5-Paclitaxel Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cy5-PaclitaxelFluorescent DyeMicrotubule/TubulinCY5Paclitaxelmolecular labelingmicroscopy imagingapoptoticInhibitorinhibitorinhibit

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Cy5-Paclitaxel

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